Identification
NameDiphenhydramine
Accession NumberDB01075  (APRD00587, DB06975)
TypeSmall Molecule
GroupsApproved
Description

A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.

Structure
Thumb
Synonyms
2-(Benzhydryloxy)-N,N-dimethylethylamine
2-diphenylmethoxy-N,N-demthylethanamine
alpha-(2-Dimethylaminoethoxy)diphenylmethane
beta-Dimethylaminoethanol diphenylmethyl ether
beta-Dimethylaminoethyl benzhydryl ether
Difenhidramina
Diphenhydraminum
N-(2-(Diphenylmethoxy)ethyl)-N,N-dimethylamine
O-benzhydryldimethylaminoethanol
β-dimethylaminoethyl benzhydryl ether
External IDs Not Available
Product Ingredients
IngredientUNIICASInChI KeyDetails
Diphenhydramine citrate4OD433S209 88637-37-0SPCKHVPPRJWQRZ-UHFFFAOYSA-NDetails
Diphenhydramine hydrochlorideTC2D6JAD40 147-24-0PCHPORCSPXIHLZ-UHFFFAOYSA-NDetails
Diphenhydramine methylbromideUJO67AO8YI 31065-89-1BDQPXVWYFLTETB-UHFFFAOYSA-MDetails
Diphenhydramine salicylate707L3YC54L 7491-10-3RTSZUSOHOIFYSY-UHFFFAOYSA-NDetails
Product Images
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Benadryl Inj. 50mg/mlLiquid50 mgIntramuscular; IntravenousWarner Lambert Canada Inc.1994-12-312000-11-27Canada
Diphenhydramine HCl Inj USP 50mg/mlLiquid50 mgIntravenousInternational Medication Systems, Limited1974-12-311997-08-15Canada
Diphenhydramine HCl Injection, USPSolution50 mgIntramuscular; IntravenousSterimax Inc1994-12-31Not applicableCanada
Diphenhydramine Hydrochloride InjectionSolution50 mgIntramuscular; IntravenousFresenius Kabi2012-02-17Not applicableCanada
Diphenhydramine Hydrochloride Injection USPLiquid50 mgIntramuscular; IntravenousSandoz Canada Incorporated1983-12-31Not applicableCanada
Diphenist 50mg/mlLiquid50 mgIntramuscular; IntravenousOmega Laboratories Ltd1997-10-28Not applicableCanada
PMS-diphenhydramine Hydrochloride Inj 50mg/mlLiquid50 mgIntramuscular; IntravenousPharmascience Inc1991-12-31Not applicableCanada
Scheinpharm Diphenhydramine Inj.50mg/mlSolution50 mgIntramuscular; IntravenousSchein Pharmaceutical Canada Inc.1996-09-302004-07-26Canada
Approved Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Diphendydramine HydrochlorideCapsule25 mg/1OralRemedy Repack2010-12-172017-06-20Us66424 0020 01 nlmimage10 1a038d6c
DiphenhydramineInjection, solution50 mg/mLIntramuscular; IntravenousFresenius Kabi2002-08-01Not applicableUs
DiphenhydramineInjection, solution50 mg/mLIntravenousRemedy Repack2013-06-132017-01-24Us
Diphenhydramine HydrochlorideCapsule50 mg/1OralCardinal Health2011-01-20Not applicableUs
Diphenhydramine HydrochlorideInjection50 mg/mLIntramuscular; IntravenousA S Medication Solutions1972-11-272017-06-20Us
Diphenhydramine HydrochlorideInjection50 mg/mLIntramuscular; IntravenousRemedy Repack2017-01-06Not applicableUs
Diphenhydramine HydrochlorideInjection50 mg/mLIntramuscular; IntravenousWest Ward Pharmaceutical1972-11-27Not applicableUs
Diphenhydramine HydrochlorideInjection, solution50 mg/mLIntramuscular; IntravenousMylan Institutional2013-05-09Not applicableUs
Diphenhydramine HydrochlorideElixir12.5 mg/5mLOralCardinal Health1982-02-10Not applicableUs
Diphenhydramine HydrochlorideInjection, solution50 mg/mLIntramuscular; IntravenousHospira, Inc.1988-11-20Not applicableUs
Diphenhydramine HydrochlorideInjection, solution50 mg/mLIntramuscular; IntravenousFresenius Kabi2013-03-26Not applicableUs
Diphenhydramine HydrochlorideInjection50 mg/mLIntramuscular; IntravenousDispensing Solutions, Inc.1972-11-27Not applicableUs
Diphenhydramine HydrochlorideInjection, solution50 mg/mLIntramuscular; IntravenousGeneral Injectables & Vaccines2010-03-01Not applicableUs
Diphenhydramine HydrochlorideInjection50 mg/mLIntramuscular; IntravenousCardinal Health2002-05-28Not applicableUs
Diphenhydramine HydrochlorideInjection, solution50 mg/mLIntramuscular; IntravenousCardinal Health1988-11-20Not applicableUs
Diphenhydramine HydrochlorideSolution12.5 mg/5mLOralPharmaceutical Associates, Inc.1982-02-10Not applicableUs
Diphenhydramine HydrochlorideInjection50 mg/mLIntramuscular; IntravenousRebel Distributors1972-11-27Not applicableUs
Diphenhydramine HydrochlorideInjection50 mg/mLIntramuscular; IntravenousTYA Pharmaceuticals1972-11-27Not applicableUs
Diphenhydramine HydrochlorideInjection, solution50 mg/mLIntramuscular; IntravenousGeneral Injectables & Vaccines2017-06-13Not applicableUs
Diphenhydramine HydrochlorideInjection, solution50 mg/mLIntramuscular; IntravenousGeneral Injectables & Vaccines2010-07-01Not applicableUs
Diphenhydramine HydrochlorideInjection50 mg/mLIntramuscular; IntravenousSina Health Inc1972-11-27Not applicableUs
Diphenhydramine HydrochlorideInjection50 mg/mLIntramuscularRemedy Repack2013-06-132016-12-15Us
Diphenhydramine HydrochlorideInjection50 mg/mLIntramuscular; IntravenousCardinal Health2011-06-28Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1OralRemedy Repack2013-03-252016-04-05Us
Diphenhydramine HydrochlorideCapsule50 mg/1OralContract Pharmacy Services Pa2010-08-05Not applicableUs00555 0059 02 nlmimage10 a62dd30e
Diphenhydramine HydrochlorideElixir25 mg/10mLOralCardinal Health1982-02-10Not applicableUs
Diphenhydramine HydrochlorideInjection50 mg/mLIntramuscularRemedy Repack2013-06-102017-12-08Us
Diphenhydramine HydrochlorideSolution12.5 mg/5mLOralPharmaceutical Associates, Inc.1982-02-10Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1OralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
Approved Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
7 Select AllergyTablet25 mg/1Oral7 Eleven2014-04-22Not applicableUs
7 Select Allergy ChildrensSolution12.5 mg/5mLOral7 Eleven2014-08-05Not applicableUs
7 Select Night Time Sleep AidLiquid50 mg/30mLOral7 Eleven2014-04-22Not applicableUs
Adult AllergySolution50 mg/20mLOralChain Drug Consortium2015-05-04Not applicableUs
Adult Allergy ReliefSolution50 mg/20mLOralWalmart Stores2017-05-03Not applicableUs
After Bite OutdoorGel20 mg/mLTopicalTender Corporation2016-11-01Not applicableUs
After Bite PlusCream20 mg/mLTopicalTender Corporation2012-07-03Not applicableUs
After Bite XtraGel20 mg/mLTopicalTender Corporation2016-11-01Not applicableUs
After StingGel20 mg/mLTopicalTender Corporation2016-11-01Not applicableUs
AfterBite with AntihistimineCream2 mL/100mLTopicalTender Corporation2012-07-032016-11-03Us
Alka-Seltzer Plus AllergyTablet25 mg/1OralBayer Health Care Llc, Consumer Care2011-11-07Not applicableUs
Aller-aideTablet25 mgOralTeva1996-05-02Not applicableCanada
Aller-aide ElixirElixir12.5 mgOralTeva1995-12-31Not applicableCanada
Aller-aide PlusTablet50 mgOralTeva1997-02-21Not applicableCanada
Aller-aide Plus Capsules 50mgCapsule50 mgOralTechnilab Pharma Inc.1996-12-311997-08-22Canada
Aller-G-timeTablet, film coated25 mg/1OralTime Cap Laboratories2012-05-01Not applicableUs
Allerdryl Cap 25mgCapsule25 mgOralValeant Canada Lp Valeant Canada S.E.C.1976-12-312014-07-30Canada
Allerdryl Cap 50mgCapsule50 mgOralValeant Canada Lp Valeant Canada S.E.C.1973-12-312014-07-30Canada
Allergies ReliefTablet, film coated25 mg/1OralMedex Merchandising, Llc2015-10-012018-04-02Us
AllergyCapsule25 mg/1OralCardinal Health (Leader) 497812016-01-31Not applicableUs
AllergySolution12.5 mg/5mLOralHyvee1992-11-11Not applicableUs
AllergyCapsule25 mg/1OralMc Kesson2016-11-25Not applicableUs
AllergyTablet25 mg/1OralCvs Health1991-08-14Not applicableUs
AllergyCapsule25 mg/1OralPublix Supermarkets, Inc.1993-08-31Not applicableUs
AllergyLiquid12.5 mg/5mLOralAccudial Pharmaceutical, Inc.2009-10-26Not applicableUs
AllergyCapsule25 mg/1OralTopcare (Topco Associates Llc)2016-07-15Not applicableUs
AllergyTablet25 mg/1OralPublix Supermarkets, Inc.1998-05-07Not applicableUs
AllergyTablet, coated25 mg/1OralDiscount Drug Mart2016-09-30Not applicableUs
AllergyTablet, coated25 mg/1OralFred's1990-03-02Not applicableUs
AllergyTablet25 mg/1OralWestern Family Foods2003-02-25Not applicableUs
AllergyTablet25 mg/1OralGreenbrier International, Inc.1990-03-02Not applicableUs
AllergyCapsule25 mg/1OralMedicine Shoppe International1990-03-15Not applicableUs
AllergyTablet25 mg/1OralVelocity Pharma2012-05-12Not applicableUs
AllergyLiquid12.5 mgOralAccudial Pharmaceutical, Inc.2010-01-11Not applicableCanada
AllergyCapsule25 mg/1OralHyvee1988-12-15Not applicableUs
AllergyTablet25 mg/1OralMc Kesson2016-11-25Not applicableUs
AllergyCapsule25 mg/1OralKroger1990-08-15Not applicableUs
AllergyLiquid12.5 mg/5mLOralAccudial Pharmaceutical, Inc.2013-02-01Not applicableUs
AllergyTablet25 mg/1OralAllegiant Health2014-12-15Not applicableUs
AllergyTablet25 mg/1OralKroger1987-09-15Not applicableUs
AllergyTablet25 mg/1OralMc Kesson2016-11-25Not applicableUs
AllergyCapsule25 mg/1OralMeijer Distribution1991-01-15Not applicableUs
AllergyCapsule25 mg/1OralCvs Health1987-12-15Not applicableUs
AllergyTablet25 mg/1OralMc Kesson2012-05-17Not applicableUs
AllergySolution12.5 mg/5mLOralH.E.B.1987-07-15Not applicableUs
AllergyLiquid12.5 mg/5mLOralKroger1987-07-15Not applicableUs
AllergyTablet25 mg/1OralMeijer Distribution1991-09-06Not applicableUs
AllergyCapsule25 mg/1OralWestern Family Foods2003-04-09Not applicableUs
AllergyCapsule25 mg/1OralMc Kesson2016-11-25Not applicableUs
AllergyTablet25 mg/1OralHyvee2016-03-01Not applicableUs
AllergyCapsule25 mg/1OralTopcare (Topco Associates Llc)2013-11-30Not applicableUs
Allergy AntihistamineCapsule25 mg/1OralValu Merchandisers Company (Best Choice)2010-08-10Not applicableUs
Allergy AntihistamineTablet25 mg/1OralCardinal Health (Leader)2012-10-30Not applicableUs
Allergy AntihistamineCapsule25 mg/1OralCardinal Health (Leader)2012-08-30Not applicableUs
Allergy AntihistamineTablet25 mg/1OralSuper Valu (Equaline)2010-07-22Not applicableUs
Allergy AntihistamineTablet25 mg/1OralP & L Development, LLC2013-08-27Not applicableUs
Allergy AntihistamineTablet25 mg/1OralSelect Corporation2012-10-15Not applicableUs
Allergy AntihistamineTablet25 mg/1OralValu Merchandisers Company (Best Choice)2010-08-27Not applicableUs
Allergy AntihistamineTablet25 mg/1OralSuper Valu (Equaline)2010-07-22Not applicableUs
Allergy Attack Relief to GoPowder25 mg/1OralBreakthrough Products Inc.2012-10-01Not applicableUs
Allergy Capsules Extra StrengthCapsule50 mgOralTanta Pharmaceuticals IncNot applicableNot applicableCanada
Allergy ChildrensLiquid12.5 mg/5mLOralWe Care Distributors Inc.2016-06-21Not applicableUs
Allergy ChildrensLiquid12.5 mg/5mLOralH.E.B.2016-02-29Not applicableUs
Allergy ChildrensLiquid12.5 mg/5mLOralCvs Health1987-07-15Not applicableUs
Allergy ChildrensSolution12.5 mg/5mLOralMeijer Distribution1987-11-15Not applicableUs
Allergy Childrens AllergyLiquid12.5 mg/5mLOralDolgencorp, Inc. (Dollar General & Rexall)2015-06-30Not applicableUs
Allergy Complete ReliefCapsule25 mg/1OralNash Finch1990-03-15Not applicableUs
Allergy Complete ReliefCapsule, liquid filled25 mg/1OralNash Finch2001-09-13Not applicableUs
Allergy Complete ReliefTablet25 mg/1OralNash Finch1990-03-02Not applicableUs
Allergy Dye-freeSolution12.5 mgOralAccudial Pharmaceutical, Inc.2012-06-01Not applicableCanada
Allergy ElixirElixir12.5 mgOralTanta Pharmaceuticals Inc1991-12-31Not applicableCanada
Allergy FormulaSolution12.5 mgOralJuno Otc IncNot applicableNot applicableCanada
Allergy FormulaTablet25 mgOralPharmascience IncNot applicableNot applicableCanada
Allergy FormulaTablet25 mgOralVita Health Products Inc1997-04-01Not applicableCanada
Allergy FormulaTablet25 mgOralGenvion CorporationNot applicableNot applicableCanada
Allergy FormulaTablet25 mgOralTeva2010-07-21Not applicableCanada
Allergy FormulaTablet25 mgOralPharmetics (2011) Inc.2009-05-08Not applicableCanada
Allergy FormulaTablet25 mgOralLaboratoires Trianon Inc2016-09-15Not applicableCanada
Allergy Formula CapletsTablet25 mgOralPerrigo International1997-09-29Not applicableCanada
Allergy Formula ElixirSolution12.5 mgOralTeva2016-10-19Not applicableCanada
Allergy Formula Junior StrengthTablet, chewable12.5 mgOralPharmetics (2011) Inc.Not applicableNot applicableCanada
Allergy Formula LiquidLiquid12.5 mgOralPerrigo International1997-09-29Not applicableCanada
Allergy Formula Liquid CapsulesCapsule25 mgOralVita Health Products Inc2008-07-11Not applicableCanada
Allergy Formula Liquid GelsCapsule25 mgOralAccucaps Industries LimitedNot applicableNot applicableCanada
Allergy Get ReliefTablet25 mg/1OralEagle Distributors,Inc.2012-06-30Not applicableUs
Allergy Liquid Gel CapsulesCapsule25 mgOralApotex CorporationNot applicableNot applicableCanada
Allergy MedicineCapsule25 mg/1OralL&R Distributors, Inc.1990-03-15Not applicableUs
Allergy MedicineTablet, film coated25 mg/1OralL&R Distributors, Inc.1990-03-02Not applicableUs
Allergy MedicineTablet25 mg/1OralCostco Wholesale1990-03-02Not applicableUs
Allergy Rapid Melts ChildrensTablet, chewable12.5 mg/1OralChain Drug Consortium2011-04-25Not applicableUs
Allergy ReilefCapsule25 mg/1OralChain Drug Consortium1990-03-15Not applicableUs
Allergy ReliefCapsule25 mg/1OralMc Kesson (Health Mart)1990-03-15Not applicableUs
Allergy ReliefCapsule25 mg/1OralArmy + Air Force Exchange Service1990-03-15Not applicableUs
Allergy ReliefCapsule25 mg/1OralValu Merchandisers Company (Best Choice)2015-09-30Not applicableUs
Allergy ReliefCapsule25 mg/1OralFred's2015-12-18Not applicableUs
Allergy ReliefTablet25 mg/1OralDolgencorp, Inc. (Dollar General & Rexall)2015-03-31Not applicableUs
Allergy ReliefCapsule25 mg/1OralSupervalu1990-03-15Not applicableUs
Allergy ReliefCapsule, liquid filled25 mg/1OralTarget Corporation.2015-06-30Not applicableUs
Allergy ReliefTablet25 mg/1OralCvs Health2016-08-19Not applicableUs
Allergy ReliefCapsule, liquid filled25 mg/1OralArmy + Air Force Exchange Service2001-09-13Not applicableUs
Allergy ReliefTablet, coated25 mg/1OralCardinal Health1990-03-02Not applicableUs
Allergy ReliefTablet25 mg/1OralWe Care Distributor Inc.2016-01-11Not applicableUs
Allergy ReliefCapsule, liquid filled25 mg/1OralPreferred Plus (Kinray)2013-11-25Not applicableUs
Allergy ReliefCapsule, liquid filled25 mg/1OralPura Cap Pharmaceutical Llc.2016-07-14Not applicableUs
Allergy ReliefCapsule25 mg/1OralMc Kesson (Health Mart)2015-10-31Not applicableUs
Allergy ReliefCapsule25 mg/1OralWalmart Stores1990-03-15Not applicableUs
Allergy ReliefCapsule25 mg/1OralSunmark (Mckesson)2011-08-26Not applicableUs
Allergy ReliefTablet25 mg/1OralMeijer2017-07-12Not applicableUs
Allergy ReliefTablet25 mg/1OralTopcare (Topco Associates Llc)2013-03-31Not applicableUs
Allergy ReliefTablet, film coated25 mg/1OralRite Aid1990-03-02Not applicableUs
Allergy ReliefTablet25 mg/1OralHealth Life Of Usa2012-05-12Not applicableUs
Allergy ReliefTablet25 mg/1OralCvs Health2015-07-212018-04-30Us
Allergy ReliefTablet, film coated25 mg/1OralTarget Corporation.1990-03-02Not applicableUs
Allergy ReliefCapsule25 mg/1OralChain Drug Marketing Association2008-11-10Not applicableUs
Allergy ReliefTablet, film coated25 mg/1OralDolgencorp1990-03-02Not applicableUs
Allergy ReliefCapsule25 mg/1OralFreds, Inc.2008-09-01Not applicableUs
Allergy ReliefTablet25 mg/1OralNavarro Discount Pharmacies, LLC2013-01-01Not applicableUs
Allergy ReliefTablet25 mg/1OralKareway Product, Inc.2011-08-18Not applicableUs
Allergy ReliefTablet, film coated25 mg/1OralSpirit Pharmaceuticals, Llc2016-08-18Not applicableUs
Allergy ReliefCapsule25 mg/1OralShopko Stores Operating2016-10-07Not applicableUs
Allergy ReliefCapsule25 mg/1OralSunmark (Mckesson)1990-03-15Not applicableUs
Allergy ReliefCapsule25 mg/1OralAldi, Inc1990-03-15Not applicableUs
Allergy ReliefCapsule25 mg/1OralH.E.B.2016-02-29Not applicableUs
Allergy ReliefTablet25 mg/1OralHealthy Accents (DZA Brands, LLC)2013-12-30Not applicableUs
Allergy ReliefTablet, film coated25 mg/1OralMeijer Distribution1990-03-02Not applicableUs
Allergy ReliefTablet25 mg/1OralMc Kesson (Health Mart)1990-03-02Not applicableUs
Allergy ReliefTablet, chewable12.5 mg/1OralAmerisource Bergen2011-04-25Not applicableUs
Allergy ReliefTablet, film coated25 mg/1OralLnk International, Inc.1990-03-02Not applicableUs50844 0329 07 nlmimage10 aa35d51e
Allergy ReliefCapsule, liquid filled25 mg/1OralPura Cap Pharmaceutical Llc.2017-07-14Not applicableUs
Allergy ReliefTablet, coated25 mg/1OralSunmark (Mckesson)1990-03-02Not applicableUs
Allergy ReliefTablet, film coated25 mg/1OralCvs Health2014-11-21Not applicableUs
Allergy ReliefTablet, film coated25 mg/1OralHarmon Store Inc.1990-03-02Not applicableUs
Allergy ReliefCapsule25 mg/1OralMeijer2014-10-31Not applicableUs
Allergy ReliefTablet25 mg/1OralShopko Stores Operating2013-09-09Not applicableUs
Allergy ReliefCapsule25 mg/1OralFamily Dollar (FAMILY WELLNESS)2016-06-30Not applicableUs
Allergy ReliefCapsule, liquid filled25 mg/1OralRite Aid2001-09-13Not applicableUs
Allergy ReliefTablet, coated25 mg/1OralWalmart Stores1990-03-02Not applicableUs
Allergy ReliefTablet, film coated25 mg/1OralCvs Health1990-03-02Not applicableUs
Allergy ReliefCapsule25 mg/1OralFamily Dollar Services1990-03-152019-10-25Us
Allergy ReliefTablet25 mg/1OralArmy + Air Force Exchange Service1990-03-02Not applicableUs
Allergy reliefCapsule25 mg/1OralSuper Valu (Equaline)2011-08-15Not applicableUs
Allergy ReliefCapsule25 mg/1OralSunmark (Mckesson)2015-09-30Not applicableUs
Allergy ReliefTablet25 mg/1OralInternational Laboratories, Llc2016-05-27Not applicableUs
Allergy ReliefCapsule, liquid filled25 mg/1OralFoodhold U.S.A.2016-10-03Not applicableUs
Allergy ReliefCapsule25 mg/1OralRite Aid1990-03-15Not applicableUs
Allergy ReliefSolution12.5 mg/5mLOralBio Pharm, Inc.2007-12-06Not applicableUs
Allergy ReliefCapsule25 mg/1OralMeijer2015-10-31Not applicableUs
Allergy ReliefTablet25 mg/1OralLnk International, Inc.1990-03-02Not applicableUs
Allergy ReliefTablet, film coated25 mg/1OralSupervalu1990-03-02Not applicableUs
Allergy ReliefCapsule, liquid filled25 mg/1OralHyvee2015-11-30Not applicableUs
Allergy ReliefTablet25 mg/1OralBetter Living Brands1990-03-02Not applicableUs
Allergy ReliefCapsule, liquid filled25 mg/1OralP & L Development, LLC2015-09-30Not applicableUs
Allergy ReliefCapsule25 mg/1OralCvs Health1990-03-15Not applicableUs
Allergy ReliefCapsule25 mg/1OralLnk International, Inc.1990-03-15Not applicableUs
Allergy ReliefTablet, coated25 mg/1OralChain Drug Marketing Association2014-06-13Not applicableUs
Allergy ReliefTablet25 mg/1OralLidl Us Llc2017-03-20Not applicableUs
Allergy ReliefCapsule25 mg/1OralBetter Living Brands1990-03-15Not applicableUs
Allergy ReliefTablet25 mg/1OralFamily Dollar Services1990-03-02Not applicableUs
Allergy Relief AntihistamineTablet25 mg/1OralSunmark (Mckesson)2011-09-28Not applicableUs
Allergy Relief AntihistamineTablet25 mg/1OralPld Acquisitions Llc Dba Avéma Pharma Solutions2010-01-02Not applicableUs
Allergy Relief AntihistamineCapsule, liquid filled25 mg/1OralP And L Development Of New York Corporation (Ready In Case)2013-02-07Not applicableUs
Allergy Relief AntihistamineCapsule, liquid filled25 mg/1OralGood Sense (Geiss, Destin & Dunn, Inc.)2013-06-06Not applicableUs
Allergy Relief AntihistamineTablet25 mg/1OralFred's2010-07-22Not applicableUs
Allergy Relief AntihistamineCapsule, liquid filled25 mg/1OralDolgencorp, Inc. (Dollar General & Rexall)2013-05-30Not applicableUs
Allergy Relief AntihistamineCapsule, liquid filled25 mg/1OralSMART SENSE (Kmart)2013-04-01Not applicableUs
Allergy Relief AntihistamineTablet25 mg/1OralPreferred Plus (Kinray)2010-10-26Not applicableUs
Allergy Relief AntihistamineCapsule, liquid filled25 mg/1OralTopcare (Topco Associates Llc)2013-05-30Not applicableUs
Allergy Relief AntihistamineCapsule, liquid filled25 mg/1OralFred's2013-04-08Not applicableUs
Allergy Relief AntihistamineTablet25 mg/1OralSIMPLY RIGHT (Sam's West, Inc.)2011-10-30Not applicableUs
Allergy Relief AntihistamineTablet25 mg/1OralCardinal Health (Leader) 497812011-09-28Not applicableUs
Allergy Relief ChildrensTablet, chewable12.5 mg/1OralMeijer Distribution2011-04-25Not applicableUs
Allergy Relief ChildrensLiquid12.5 mg/5mLOralASSURED / DOLLAR TREE (Greenbrier International, Inc.)2016-06-30Not applicableUs
Allergy Relief ChildrensTablet, chewable12.5 mg/1OralSupervalu2009-03-20Not applicableUs
Allergy Relief ChildrensSolution12.5 mg/5mLOralCvs Health2015-09-03Not applicableUs
Allergy Relief CompleteTablet25 mg/1OralWin Co Foods, Llc,1990-03-02Not applicableUs
Allergy Relief CompleteCapsule25 mg/1OralWin Co Foods, Llc,1990-03-15Not applicableUs
Allergy Relief Dye FreeCapsule, liquid filled25 mg/1OralWestern Family Foods2015-09-30Not applicableUs
Allergy Relief Dye FreeCapsule, liquid filled25 mg/1OralSMART SENSE (Kmart)2016-07-31Not applicableUs
Allergy Relief Dye FreeCapsule, liquid filled25 mg/1OralKroger2016-12-31Not applicableUs
Allergy Relief Dye FreeCapsule, liquid filled25 mg/1OralGood Sense (Geiss, Destin & Dunn, Inc.)2016-03-31Not applicableUs
Allergy Relief Dye FreeCapsule, liquid filled25 mg/1OralDolgencorp, Inc. (Dollar General & Rexall)2017-05-31Not applicableUs
Allergy Relief Dye FreeCapsule, liquid filled25 mg/1OralDolgencorp, Inc. (Dollar General & Rexall)2015-10-31Not applicableUs
Allergy Relief Dye FreeCapsule, liquid filled25 mg/1OralTopcare (Topco Associates Llc)2016-02-29Not applicableUs
Allergy Relief DYE-FREECapsule, liquid filled25 mg/1OralAmerisource Bergen2015-03-01Not applicableUs
Allergy Relief Dye-FreeCapsule, liquid filled25 mg/1OralChain Drug Marketing Association2015-03-01Not applicableUs
Allergy Relief Dye-FreeCapsule, liquid filled25 mg/1OralWalmart Stores2015-03-01Not applicableUs
Allergy Relief Dye-FreeCapsule, liquid filled25 mg/1OralHarmon Store Inc.2015-03-01Not applicableUs
Allergy Relief Dye-FreeCapsule, liquid filled25 mg/1OralCardinal Health2015-03-01Not applicableUs
Allergy Relief Dye-FreeTablet25 mg/1OralCvs Health2013-02-07Not applicableUs
Allergy Relief Dye-FreeCapsule, liquid filled25 mg/1OralCvs Health2015-03-01Not applicableUs
Allergy Relief Dye-Free Liquid GelsCapsule, liquid filled25 mg/1OralArmy + Air Force Exchange Service2015-03-01Not applicableUs
Allergy Relief ElixirElixir12.5 mgOralPharmetics (2011) Inc.Not applicableNot applicableCanada
Allergy Relief Extra Strength NighttimeTablet50 mg/1OralP & L Development, LLC2015-09-30Not applicableUs
Allergy Relief Extra Strength NighttimeTablet50 mg/1OralHyvee2014-11-30Not applicableUs
Allergy Relief NighttimeTablet25 mg/1OralMeijer2015-01-20Not applicableUs
Allergy Relief NighttimeTablet, film coated25 mg/1OralWalgreen2015-01-20Not applicableUs
Allergy SoftgelCapsule, liquid filled25 mg/1OralAllegiant Health2014-12-15Not applicableUs
Allergy SoftgelCapsule, liquid filled25 mg/1OralAi Ping Pharmaceutical, Inc.2015-01-31Not applicableUs
Allergy Tablets 25mgTablet25 mgOralTanta Pharmaceuticals Inc1992-12-31Not applicableCanada
Allergy Tablets Extra StrengthTablet50 mgOralTanta Pharmaceuticals Inc1997-04-21Not applicableCanada
AllernixTablet25 mgOralTeva1995-12-31Not applicableCanada
Allernix Cap 50mg UCapsule50 mgOralTechnilab Pharma Inc.1991-12-311997-08-22Canada
Allernix ElixirSolution12.5 mgOralTeva1991-12-31Not applicableCanada
Allernix Extra StrengthTablet50 mgOralTeva1995-12-31Not applicableCanada
Allernix HCl Cap 25mg UCapsule25 mgOralTechnilab Pharma Inc.1991-12-311997-08-22Canada
Anti-ItchGel2 g/100gTopicalNavarro Discount Pharmacies, LLC2013-01-18Not applicableUs
Anti-itch CreamCream2 %TopicalTaro Pharmaceuticals, Inc.2007-12-20Not applicableCanada
Anti-itch Diphenhydramine Hydrochloride CreamCream2.0 %TopicalCrlsNot applicableNot applicableCanada
Antihistamine AllergyCapsule25 mg/1OralH.E.B.2011-03-23Not applicableUs
Antihistamine AllergyCapsule25 mg/1OralH.E.B.1989-07-15Not applicableUs
Antihistamine AllergyTablet, coated25 mg/1OralH.E.B.1990-03-02Not applicableUs
Antihistamine AllergyTablet25 mg/1OralH.E.B.1989-08-15Not applicableUs
Antihistamine AllergyTablet25 mg/1OralH.E.B.2011-12-01Not applicableUs
Antihistimine AllergyTablet, coated25 mg/1OralAvema Pharma Solutions2012-04-302017-04-14Us
AphenapTablet25 mg/1OralA P J Laboratories Limited2013-03-01Not applicableUs
Assured Allergy ReliefTablet, film coated25 mg/1OralSpirit Pharmaceuticals, Llc2016-07-01Not applicableUs
Aurodryl Childrens AllergySolution12.5 mg/5mLOralAurohealth LLC2014-09-10Not applicableUs
Aurodryl childrens AllergySolution12.5 mg/5mLOralAurohealth LLC2015-05-13Not applicableUs
AuroZzil NIGHTTIME SLEEP-AIDSolution50 mg/30mLOralAurohealth LLC2015-05-15Not applicableUs
Bactimicina Childrens AllergyLiquid12.5 mg/5mLOralDLC Laboratories, Inc.2015-06-17Not applicableUs
BanophenCapsule50 mg/1OralUnit Dose Services2009-01-02Not applicableUs
BanophenLiquid12.5 mg/5mLOralNu Care Pharmaceuticals,inc.2006-11-20Not applicableUs
BanophenTablet25 mg/1OralMajor1990-03-02Not applicableUs
BanophenCapsule25 mg/1OralMajor1990-03-15Not applicableUs
BanophenTablet25 mg/1OralCardinal Health1990-03-02Not applicableUs
BanophenCapsule50 mg/1OralMajor2009-11-02Not applicableUs
BanophenLiquid12.5 mg/5mLOralMajor2006-11-20Not applicableUs
BanophenTablet25 mg/1OralCarilion Materials Management1990-03-02Not applicableUs00904 5551 59 nlmimage10 e93ff4df
BanophenCapsule50 mg/1OralRemedy Repack2015-12-232017-04-26Us
BanophenLiquid12.5 mg/5mLOralAtlantic Biologicals Corps.2012-08-24Not applicableUs
BanophenTablet25 mg/1OralRemedy Repack2017-03-06Not applicableUs
BanophenLiquid12.5 mg/5mLOralMajor2012-08-24Not applicableUs
BanophenLiquid12.5 mg/5mLOralProficient Rx LP2006-11-20Not applicableUs
Basic Care Allergy ReliefTablet25 mg/1OralL. Perrigo Company2017-08-10Not applicableUs
Basic Care Childrens Allergy ReliefSolution12.5 mg/5mLOralL. Perrigo Company2017-08-29Not applicableUs
BenadrylTablet, film coated25 mg/1OralJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2008-09-01Not applicableUs
BenadrylCapsule, liquid filled25 mg/1OralCentral Texas Community Health Centers2009-03-01Not applicableUs
BenadrylTablet, film coated25 mg/1OralMechanical Servants, Llc2008-09-01Not applicableUs
BenadrylTablet, film coated25 mg/1OralLil' Drug Store Products, Inc.2010-09-16Not applicableUs
BenadrylTablet, film coated25 mg/1OralRemedy Repack2016-08-31Not applicableUs
BenadrylKitJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2017-06-12Not applicableUs
Benadryl 25mg CapletsTablet25 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc1993-12-31Not applicableCanada
Benadryl AllergySolution12.5 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Benadryl AllergyTablet, coated25 mg/1OralRebel Distributors2009-01-01Not applicableUs
Benadryl Allergy Liqui-GelsCapsule, liquid filled25 mg/1OralJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2009-03-01Not applicableUs
Benadryl Allergy LiquigelsCapsule25 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2008-05-05Not applicableCanada
Benadryl Allergy Quick Dissolve StripsStrip25 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Benadryl Allergy TabletsTablet, chewable12.5 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc1998-03-06Not applicableCanada
Benadryl Capsules 50mgCapsule50 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc1994-12-312016-01-22Canada
Benadryl Childrens Liquid 6.25mg/5mlLiquid6.25 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc1991-12-31Not applicableCanada
Benadryl Cream 2%Cream2 %TopicalMcneil Consumer Healthcare Division Of Johnson & Johnson Inc1993-12-31Not applicableCanada
Benadryl ElixirElixir12.5 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc1994-12-31Not applicableCanada
Benadryl Extra Strength CapletsTablet50 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc1999-04-06Not applicableCanada
Benadryl Extra Strength Itch StoppingGel20 mg/mLTopicalJohnson & Johnson2013-10-01Not applicableUs
Benadryl Extra Strength Itch StoppingGel20 mg/mLTopicalJohnson & Johnson2013-02-132019-09-01Us
Benadryl Fast MeltsTablet, chewable25 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Benadryl Itch Stopping GelGel2 %TopicalMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Benadryl UltratabsTablet25 mg/1OralNavajo Manuracturing Company2016-09-22Not applicableUs
BenaldrylTablet25 mg/250mgOralAjes Pharmaceuticals,LLC2012-09-01Not applicableUs
Benylin Cough and Cold Night StripsStrip25 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Benylin Night CoughCapsule25 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2007-10-012009-08-06Canada
Benylin Night for ChildrenLiquid6.25 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2013-01-28Not applicableCanada
Benylin Sleep TimeLiquid12.5 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2012-08-31Not applicableCanada
Berkley and Jensen AllergyTablet25 mg/1OralBJWC2008-10-31Not applicableUs
Berkley and Jensen Allergy ReliefTablet25 mg/1OralBJWC2013-12-10Not applicableUs
Calmex Tab 25mgTablet25 mgOralNovopharm Limited1981-12-312015-10-26Canada
CAREALL DiphenhydramineTablet, coated25 mg/1OralNew World Imports2016-04-28Not applicableUs
Careone AllergyCapsule25 mg/1OralAmerican Sales Company2004-07-27Not applicableUs
CareOne Allergy MedicationTablet25 mg/1OralAmerican Sales Company2004-05-24Not applicableUs
CareOne Allergy ReliefCapsule25 mg/1OralAmerican Sales Company2016-10-28Not applicableUs
CareOne Childrens AllergySolution12.5 mg/5mLOralAmerican Sales Company2015-10-28Not applicableUs
CareOne Childrens Allergy ReliefSolution12.5 mg/5mLOralAmerican Sales Company2016-04-12Not applicableUs
Careone Nighttime Sleep AidTablet25 mg/1OralAmerican Sales Company2004-04-13Not applicableUs
CareOne Nighttime Sleep AidCapsule, liquid filled25 mg/1OralAmerican Sales Company2014-01-28Not applicableUs
Children's Allergy FormulaSyrup6.25 mgOralPharmascience Inc2004-11-01Not applicableCanada
Children's Allergy FormulaLiquid6.25 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.2000-05-022002-07-31Canada
Children's Allergy Relief LiquidLiquid6.25 mgOralPharmetics (2011) Inc.Not applicableNot applicableCanada
Children's Benadryl Allergy FastmeltTablet19 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Children's Benadryl Allergy StripsStrip12.5 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Children's Cough, Cold & Allergy StripsStrip19 mgOralVita Health Products Inc2007-09-072011-07-20Canada
Children's Liquid Allergy FormulaLiquid6.25 mgOralJamp Pharma Corporation2004-06-25Not applicableCanada
Childrens AllergyLiquid12.5 mg/5mLOralAafes/Your Military Exchanges2015-09-30Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralHarris Teeter2010-01-19Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralSelect Brand Dist.2015-12-31Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralRite Aid2009-09-04Not applicableUs
Childrens AllergySolution12.5 mg/5mLOralDolgencorp2017-03-18Not applicableUs
Childrens AllergyTablet, chewable12.5 mg/1OralL&R Distributors, Inc.2009-03-202017-05-16Us
Childrens AllergyLiquid12.5 mg/5mLOralDe Moulas Market Basket2012-09-11Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralValu Merchandisers Company (Best Choice)2015-03-31Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralQuality Choice (Chain Drug Marketing Association, Inc.)2014-05-30Not applicableUs
Childrens AllergySolution12.5 mg/5mLOralAmerisource Bergen2016-05-20Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralBest Choice2009-04-282017-04-14Us
Childrens AllergyLiquid12.5 mg/5mLOralP & L Development, LLC2015-03-31Not applicableUs
Childrens AllergyTablet12.5 mg/1OralCapricorn Pharma Inc.2010-09-29Not applicableUs
Childrens AllergySolution12.5 mg/5mLOralChain Drug Consortium2015-05-04Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralSafeway2009-02-03Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralDiscount Drug Mart2015-01-12Not applicableUs
Childrens AllergySolution12.5 mg/5mLOralPublix Supermarkets, Inc.2014-02-11Not applicableUs
Childrens AllergySolution12.5 mg/5mLOralMeijer Distribution2017-07-12Not applicableUs
Childrens AllergySyrup12.5 mg/5mLOralTarget Corporation.2016-07-31Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralDollar General2000-01-012017-05-26Us
Childrens AllergyLiquid12.5 mg/5mLOralFred's2015-04-30Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralQuality Choice (Chain Drug Marketing Association, Inc.)2014-06-30Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralChain Drug Consortium2012-09-24Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralRite Aid2009-07-30Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralChain Drug Consortium2012-09-11Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralFamily Dollar (FAMILY WELLNESS)2015-02-28Not applicableUs
Childrens AllergySolution12.5 mg/5mLOralCdma2014-09-10Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralFamily Dollar2009-06-302017-06-29Us
Childrens AllergyLiquid12.5 mg/5mLOralAmerican Sales Company2009-08-292017-05-04Us
Childrens AllergyLiquid12.5 mg/5mLOralP & L Development, LLC2009-07-29Not applicableUs
Childrens AllergyLiquid12.5 mg/5mLOralNash Finch2000-01-012017-06-20Us
Childrens AllergyLiquid12.5 mg/5mLOralH.E.B.2010-03-022017-06-29Us
childrens Allergy Dye Free Wal DrylLiquid12.5 mg/5mLOralWalgreen2017-08-31Not applicableUs
Childrens Allergy MeltsTablet, chewable12.5 mg/1OralTarget Corporation.2011-04-25Not applicableUs
Childrens Allergy MeltsTablet, chewable12.5 mg/1OralTarget Corporation.2009-03-20Not applicableUs
Childrens Allergy ReliefLiquid12.5 mg/5mLOralMarc Glassman, Inc.2014-12-02Not applicableUs
Childrens Allergy ReliefLiquid12.5 mg/5mLOralApta Pharma Inc.2013-08-21Not applicableUs
Childrens Allergy ReliefTablet, chewable12.5 mg/1OralCvs Health2009-03-20Not applicableUs
Childrens Allergy ReliefSolution12.5 mg/5mLOralShopko Stores Operating2013-09-12Not applicableUs
Childrens Allergy ReliefSolution12.5 mg/5mLOralLidl Us Llc2017-05-18Not applicableUs
Childrens Allergy ReliefLiquid12.5 mg/5mLOralRite Aid2013-11-18Not applicableUs
Childrens Allergy ReliefTablet, chewable12.5 mg/1OralWalmart Stores2011-04-25Not applicableUs
Childrens Allergy ReliefTablet, chewable12.5 mg/1OralRite Aid2011-04-25Not applicableUs
Childrens Allergy ReliefSolution12.5 mg/5mLOralKroger2014-02-04Not applicableUs
Childrens allergy reliefLiquid12.5 mg/5mLOralMc Kesson2013-08-08Not applicableUs
Childrens Allergy ReliefSolution12.5 mg/5mLOralCardinal Health2017-05-02Not applicableUs
Childrens Allergy Relief Dye FreeTablet, chewable12.5 mg/1OralCvs Health2015-03-01Not applicableUs
Childrens Allergy Relief Dye Free CherryLiquid12.5 mg/5mLOralWin Co Foods, Llc,2014-12-12Not applicableUs
Childrens Benadryl ALLERGYSolution12.5 mg/5mLOralJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2008-07-01Not applicableUs
Childrens Benadryl ChewablesTablet, chewable12.5 mg/1OralJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2016-07-11Not applicableUs
Childrens Benadryl DYE-FREE ALLERGYSolution12.5 mg/5mLOralJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2008-07-01Not applicableUs
Childrens Complete AllergySolution12.5 mg/5mLOralWestern Family Foods1993-09-08Not applicableUs
Childrens Dye Free AllergyLiquid12.5 mg/5mLOralP & L Development, LLC2015-02-28Not applicableUs
Childrens Dye Free Allergy ReliefSolution12.5 mg/5mLOralCardinal Health2017-05-02Not applicableUs
Childrens Wal-Dryl AllergyTablet, chewable12.5 mg/1OralWalgreen2011-04-25Not applicableUs
Childrens Wal-Dryl AllergyTablet, chewable12.5 mg/1OralWalgreen2009-03-20Not applicableUs
Childrens WAL-DRYL Single-Use AllergyLiquid12.5 mg/5mLOralWalgreen2011-08-25Not applicableUs
Circle K Allergy AntihistamineTablet25 mg/1OralLil' Drug Store Products, Inc.2014-11-01Not applicableUs
Circle K Allergy AntihistamineTablet25 mg/1OralLil' Drug Store Products, Inc.2014-11-01Not applicableUs
Circle K Allergy AntihistamineTablet25 mg/1OralLil' Drug Store Products, Inc.2014-11-01Not applicableUs
Clear Allergy Formula for Children and AdultsLiquid6.25 mgOralPerrigo International1997-09-292001-03-09Canada
Clear TimeTablet, film coated25 mg/1OralHyvee2015-02-16Not applicableUs
CleartimeTablet, film coated25 mg/1OralWestern Family Foods2015-03-04Not applicableUs
Complete AllergyTablet25 mg/1OralGreat Lakes Wholesale, Marketing, and Sales, Inc.1990-03-02Not applicableUs
Complete AllergyCapsule, liquid filled25 mg/1OralWestern Family Foods2013-12-30Not applicableUs
Complete AllergyTablet, film coated25 mg/1OralChain Drug Consortium1990-03-02Not applicableUs
Complete Allergy AntihistamineTablet25 mg/1OralChain Drug Consortium2010-07-13Not applicableUs
Complete Allergy MedicineCapsule25 mg/1OralChain Drug Consortium2011-03-23Not applicableUs
Complete Allergy MedicineCapsule25 mg/1OralSalado Sales, Inc.1990-03-15Not applicableUs
Complete Allergy MedicineTablet25 mg/1OralSave A Lot Food Stores, Ltd.1990-03-02Not applicableUs
Complete Allergy MedicineCapsule25 mg/1OralChain Drug Consortium2011-03-23Not applicableUs
Complete Allergy ReliefTablet, coated25 mg/1OralNew World Imports2010-11-112017-09-01Us
Complete Allergy SoftgelCapsule, liquid filled25 mg/1OralChain Drug Consortium2014-12-29Not applicableUs
Compoz MAXIMUM STRENGTH nighttime sleep aidCapsule, liquid filled50 mg/1OralMedtech Laboratories, Inc.2016-01-15Not applicableUs
ConRx AllergyTablet25 mg/1OralEagle Distributors,Inc.2013-02-15Not applicableUs
Correct Dose Childrens Allergy ReliefLiquid12.5 mg/5mLOralBfs Pharma, Inc.2011-06-15Not applicableUs
CVS Health Childrens Allergy ReliefLiquid12.5 mg/5mLOralCvs Health2015-09-07Not applicableUs
CVS Health Nighttime Sleep-AidLiquid50 mg/30mLOralCvs Health2015-02-11Not applicableUs
Cvs Maximum Strength Itch ReliefGel20.5 mg/mLTopicalCvs Health2011-08-10Not applicableUs
CVS Pharmacy Pre-measured spoon Childrens ALLERGY MEDICATIONLiquid12.5 mg/5mLOralCvs Health2011-08-25Not applicableUs
Dalay Maximum StrengthTablet25 mg/1OralGenomma Labs2015-04-21Not applicableUs
Dg Health AllergyCapsule25 mg/1OralDolgencorp2010-02-22Not applicableUs
DG Health AllergyTablet25 mg/1OralDolgencorp2010-01-30Not applicableUs
Dg Health Allergy ChildrensSolution12.5 mg/5mLOralDolgencorp2010-01-29Not applicableUs
DG Health Maximum Strength Sleep AidCapsule, liquid filled50 mg/1OralDolgencorp, Inc. (Dollar General & Rexall)2012-11-29Not applicableUs
Dg Health Sleep AidTablet25 mg/1OralDolgencorp2010-01-24Not applicableUs
Dg Health Sleep AidSolution50 mg/30mLOralDolgencorp2015-05-11Not applicableUs
DG Health Sleep AidTablet25 mg/1OralDolgencorp2009-12-04Not applicableUs
Dimetane Allergy TabletsTablet38.0 mgOralPfizer Laboratories Div Pfizer Inc.2009-01-20Not applicableCanada
Diphendydramine HydrochlorideCapsule25 mg/1OralContract Pharmacy Services Pa2010-08-05Not applicableUs
Diphendydramine HydrochlorideCapsule50 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2009-01-02Not applicableUs
Diphendydramine HydrochlorideCapsule50 mg/1OralContract Pharmacy Services Pa2010-08-05Not applicableUs
DiphenhistTablet25 mg/1OralRugby2006-09-26Not applicableUs
DiphenhistCapsule25 mg/1OralRugby2014-03-17Not applicableUs
DiphenhistCapsule25 mg/1OralRugby2006-05-30Not applicableUs
DiphenhistLiquid12.5 mg/5mLOralRebel Distributors2009-09-26Not applicableUs
DiphenhistLiquid12.5 mg/5mLOralRugby2009-09-26Not applicableUs
DiphenhydramineTablet, coated25 mg/1OralAAA Pharmaceutical, Inc.2012-12-22Not applicableUs
DiphenhydramineTablet, coated25 mg/1OralSam's West, Inc1990-03-02Not applicableUs
DiphenhydramineCapsule25 mg/1OralPurine Pharma Llc2014-07-31Not applicableUs
DiphenhydramineCapsule, coated25 mg/1OralSam's West, Inc1990-03-02Not applicableUs
DiphenhydramineCapsule25 mg/1OralRebel Distributors2007-01-01Not applicableUs66424 0021 10 nlmimage10 18158c4c
DiphenhydramineCapsule25 mg/1OralRebel Distributors2007-01-01Not applicableUs
DiphenhydramineTablet25 mgOralRanbaxy Inc.Not applicableNot applicableCanada
DiphenhydramineCapsule50 mg/1OralPurine Pharma Llc2014-07-31Not applicableUs
DiphenhydramineSolution12.5 mg/5mLOralCentral Texas Community Health Centers2003-08-21Not applicableUs
DiphenhydramineTablet, coated25 mg/1OralNew World Imports2010-09-092020-08-01Us
DiphenhydramineCapsule25 mg/1OralAAA Pharmaceutical, Inc.2012-12-22Not applicableUs
DiphenhydramineCapsule50 mg/1OralH.J. Harkins Company2011-08-17Not applicableUs
Diphenhydramine HCLCapsule25 mg/1OralNucare Pharmaceuticals, Inc.2010-01-27Not applicableUs
Diphenhydramine HCLCapsule25 mg/1OralBlenheim Pharmacal, Inc.2010-05-12Not applicableUs
Diphenhydramine HCLCapsule50 mg/1OralSda Laboratories2010-01-27Not applicableUs
Diphenhydramine HCLCapsule25 mg/1OralPreferreed Pharmaceuticals Inc.2013-03-27Not applicableUs
Diphenhydramine HClTablet25 mg/1OralContract Pharmacal Corporation2004-01-01Not applicableUs
Diphenhydramine HClCapsule50 mg/1OralCardinal Health2009-01-02Not applicableUs
Diphenhydramine HCLCapsule50 mg/1OralNucare Pharmaceuticals, Inc.2010-01-27Not applicableUs
Diphenhydramine HClTablet50 mg/1OralRugby2007-07-13Not applicableUs
Diphenhydramine HClCapsule, liquid filled20 mg/1OralAi Ping Pharmaceutical, Inc.2015-01-31Not applicableUs
Diphenhydramine HCLCapsule50 mg/1OralNucare Pharmaceuticals, Inc.2010-01-27Not applicableUs
Diphenhydramine HCLCapsule50 mg/1OralPreferreed Pharmaceuticals Inc.2010-01-27Not applicableUs
Diphenhydramine HclCapsule, liquid filled25 mg/1OralAgile Pharmachem2013-10-15Not applicableUs
Diphenhydramine HClTablet50 mg/1OralContract Pharmacal Corporation2004-01-01Not applicableUs
Diphenhydramine HCLCapsule25 mg/1OralNucare Pharmaceuticals, Inc.2010-01-27Not applicableUs
Diphenhydramine HClCapsule25 mg/1OralCardinal Health2011-06-03Not applicableUs
Diphenhydramine HCLCapsule25 mg/1OralRemedy Repack2017-03-02Not applicableUs
Diphenhydramine HCLCapsule25 mg/1OralPhysicians Total Care, Inc.2010-01-27Not applicableUs
Diphenhydramine HCLCapsule50 mg/1OralRemedy Repack2017-05-11Not applicableUs
Diphenhydramine HCLCapsule50 mg/1OralProficient Rx LP2010-01-27Not applicableUs
Diphenhydramine HClCapsule, liquid filled25 mg/1OralSoftech Pharma Pvt. Ltd.2013-01-01Not applicableUs
Diphenhydramine HCLCapsule25 mg/1OralSda Laboratories2010-01-27Not applicableUs
Diphenhydramine HCl 25 mgCapsule25 mg/1OralReliable 1 Laboratories2015-11-01Not applicableUs
Diphenhydramine HCL 25 mgTablet25 mg/1OralReliable 1 Laboratories2015-11-01Not applicableUs
Diphenhydramine HCl 25mg 24ct BlisterCapsule, gelatin coated25 mg/1OralAccucaps Industries Limited2016-09-21Not applicableUs
Diphenhydramine HCl Allergy AntihistamineTablet25 mg/1OralMedline Industries2013-03-30Not applicableUs
Diphenhydramine HCl Children's LiquidSyrup6.25 mgOralLaboratoires Confab Inc2002-06-19Not applicableCanada
Diphenhydramine HydrochlorideCapsule25 mg/1OralA S Medication Solutions2007-05-242017-06-20Us
Diphenhydramine HydrochlorideCapsule50 mg/1OralLake Erie Medical Dba Quality Care Produts Llc2011-12-05Not applicableUs
Diphenhydramine HydrochlorideSolution50 mg/20mLOralCvs Health2015-11-02Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralA S Medication Solutions2009-01-022017-06-20Us
Diphenhydramine HydrochlorideTablet, film coated25 mg/1OralAurohealth LLC2016-03-01Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1Oralbryant ranch prepack2007-05-24Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralCardinal Health2017-01-13Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1OralAdvance Pharmaceutical Inc.1989-10-05Not applicableUs
Diphenhydramine HydrochlorideTablet, film coated25 mg/1OralHIMPRIT PHARMACHEM PVT LTD2010-03-01Not applicableUs
Diphenhydramine HydrochlorideCapsule, liquid filled50 mg/1OralHumanwell Pura Cap Pharmaceutical (Wuhan), Ltd.2014-08-13Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1OralRemedy Repack2015-03-242017-06-09Us
Diphenhydramine HydrochlorideCapsule25 mg/1OralEpic Pharma, LLC2016-11-22Not applicableUs
Diphenhydramine HydrochlorideSolution50 mg/20mLOralAmerisource Bergen2016-05-18Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralCvs Health2017-08-18Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralNucare Pharmaceuticals, Inc.2007-05-24Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1OralMajor2009-01-02Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1OralQualitest2007-05-242018-06-30Us
Diphenhydramine HydrochlorideCapsule25 mg/1Oralbryant ranch prepack2000-05-01Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1OralPhysicians Total Care, Inc.2000-05-01Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralAdvance Pharmaceutical Inc.1989-09-12Not applicableUs
Diphenhydramine HydrochlorideTablet, film coated25 mg/1OralHIMPRIT PHARMACHEM PVT LTD2010-03-01Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralContract Pharmacy Services Pa2010-08-30Not applicableUs
Diphenhydramine HydrochlorideCapsule, liquid filled25 mg/1OralHumanwell Pura Cap Pharmaceutical (Wuhan), Ltd.2013-09-15Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralRemedy Repack2015-03-262017-04-08Us
Diphenhydramine HydrochlorideCapsule50 mg/1OralRichmond Pharmaceuticals2000-02-15Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1OralWalgreens2017-07-20Not applicableUs
Diphenhydramine HydrochlorideSolution50 mg/20mLOralAurohealth LLC2015-08-01Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2009-01-02Not applicableUs
Diphenhydramine HydrochlorideCapsule, liquid filled25 mg/1OralRite Aid2016-09-30Not applicableUs
Diphenhydramine HydrochlorideSolution50 mg/20mLOralDolgencorp2016-02-22Not applicableUs
Diphenhydramine HydrochlorideTablet25 mg/1OralAAA Pharmaceutical, Inc.2012-12-15Not applicableUs
Diphenhydramine HydrochlorideCapsule, liquid filled50 mg/1OralSpirit Pharmaceuticals, Llc2010-06-01Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralLake Erie Medical Dba Quality Care Produts Llc2000-05-01Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1OralClinical Solutions Wholsesale2007-05-242017-07-03Us
Diphenhydramine HydrochlorideCapsule25 mg/1OralProficient Rx LP2007-05-24Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralRemedy Repack2017-04-19Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralRemedy Repack2012-06-072017-01-13Us
Diphenhydramine HydrochlorideCapsule25 mg/1OralA S Medication Solutions2007-05-242017-06-20Us
Diphenhydramine HydrochlorideCapsule50 mg/1OralPreferreed Pharmaceuticals Inc.2013-03-19Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralA S Medication Solutions2007-05-24Not applicableUs
Diphenhydramine HydrochlorideSolution50 mg/30mLOralFred's2015-01-31Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1OralLake Erie Medical Dba Quality Care Produts Llc2007-05-24Not applicableUs
Diphenhydramine HydrochlorideCapsule, liquid filled25 mg/1OralHumanwell Pura Cap Pharmaceutical (Wuhan), Ltd.2013-04-15Not applicableUs
Diphenhydramine HydrochlorideTablet, coated25 mg/1OralAAA Pharmaceutical, Inc.2012-12-15Not applicableUs
Diphenhydramine HydrochlorideSolution25 mg/10mLOralAurohealth LLC2014-11-26Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralAventura Pharmaceuticals, Llc2015-10-14Not applicableUs
Diphenhydramine HydrochlorideTablet25 mg/1OralAdvance Pharmaceutical Inc.2006-09-26Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralUnit Dose Services2007-05-24Not applicableUs
Diphenhydramine HydrochlorideCapsule, liquid filled25 mg/1OralHumanwell Pura Cap Pharmaceutical (Wuhan), Ltd.2014-10-14Not applicableUs
Diphenhydramine HydrochlorideTablet, coated25 mg/1OralAvema Pharma Solutions2010-01-022017-04-14Us
Diphenhydramine HydrochlorideCapsule50 mg/1OralEpic Pharma, LLC2016-11-22Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1OralProficient Rx LP2007-05-24Not applicableUs
Diphenhydramine hydrochlorideCapsule25 mg/1OralCentral Texas Community Health Centers1990-03-15Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralMajor2009-01-02Not applicableUs
Diphenhydramine HydrochlorideTablet25 mg/1OralSimpex Pharma Pvt. Ltd2012-11-15Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralEon Labs, Inc.2000-05-01Not applicableUs
Diphenhydramine HydrochlorideLiquid12.5 mg/5mLOralPhysicians Total Care, Inc.2002-10-22Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1OralDirectrx2014-01-01Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralRed Pharm Drug, Inc.2000-05-01Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1OralA S Medication Solutions2007-05-242017-06-20Us
Diphenhydramine HydrochlorideSolution50 mg/20mLOralAhold U.S.A., Inc.2015-08-10Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralRemedy Repack2016-12-132017-08-09Us
Diphenhydramine HydrochlorideCapsule50 mg/1OralA S Medication Solutions2007-05-242017-06-20Us
Diphenhydramine HydrochlorideTablet, coated25 mg/1OralBonita Pharmaceuticals LLC2013-05-21Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralA S Medication Solutions2007-05-242017-06-20Us
Diphenhydramine HydrochlorideCapsule25 mg/1OralTYA Pharmaceuticals2007-05-24Not applicableUs
Diphenhydramine HydrochlorideCapsule, liquid filled50 mg/1OralHumanwell Pura Cap Pharmaceutical (Wuhan), Ltd.2013-04-15Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralRichmond Pharmaceuticals2000-02-15Not applicableUs
Diphenhydramine HydrochlorideSolution50 mg/20mLOralAurohealth LLC2014-11-26Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralProficient Rx LP2009-01-02Not applicableUs
Diphenhydramine HydrochlorideSolution50 mg/20mLOralDiscount Drug Mart2016-02-11Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralDirectrx2015-01-01Not applicableUs
Diphenhydramine HydrochlorideTablet25 mg/1OralAAA Pharmaceutical, Inc.2012-12-15Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralLake Erie Medical Dba Quality Care Produts Llc2007-05-24Not applicableUs
Diphenhydramine HydrochlorideTablet, coated25 mg/1OralTime Cap Laboratories2010-03-01Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralQualitest2007-05-242020-03-30Us
Diphenhydramine HydrochlorideCapsule25 mg/1OralRemedy Repack2016-11-07Not applicableUs
Diphenhydramine HydrochlorideCapsule50 mg/1OralEon Labs, Inc.2000-05-01Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralPreferreed Pharmaceuticals Inc.2013-03-19Not applicableUs
Diphenhydramine HydrochlorideLiquid12.5 mg/5mLOralPhysicians Total Care, Inc.2006-06-29Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralA S Medication Solutions2007-05-24Not applicableUs
Diphenhydramine HydrochlorideCapsule25 mg/1OralClinical Solutions Wholsesale2007-05-242017-07-03Us00603 3339 21 nlmimage10 44392249
Diphenhydramine Hydrochloride 25 Mg CapletTablet25 mgOralJamp Pharma Corporation2005-09-12Not applicableCanada
Diphenhydramine Hydrochloride 25 Mg TabletTablet25 mgOralNobel Pharm Enr.2000-02-012014-05-27Canada
Diphenhydramine Hydrochloride 25mgCapsule25 mgOralStrides Pharma IncNot applicableNot applicableCanada
Diphenhydramine Hydrochloride 50 Mg CapletTablet50 mgOralNobel Pharm Enr.2000-02-012014-05-27Canada
Diphenhydramine Hydrochloride 50 Mg CapsuleCapsule50 mgOralNobel Pharm Enr.1983-12-312016-08-25Canada
Diphenhydramine Hydrochloride 50 Mg Capsules USP Extra Strength Sleep AidCapsule50 mgOralPharmetics (2011) Inc.2008-07-022010-07-12Canada
Diphenhydramine Hydrochloride 50mg CapletTablet50 mgOralJamp Pharma Corporation2005-09-12Not applicableCanada
Diphenhydramine Hydrochloride 50mg USPCapsule50 mgOralStrides Pharma IncNot applicableNot applicableCanada
Diphenhydramine Hydrochloride Caplets 25mgTablet25 mgOralMarcan Pharmaceuticals IncNot applicableNot applicableCanada
Diphenhydramine Hydrochloride Caplets 50 mgTablet50 mgOralMarcan Pharmaceuticals IncNot applicableNot applicableCanada
Diphenhydramine Hydrochloride Elixir U.S.P.Elixir12.5 mgOralLaboratoires Confab Inc2004-04-012015-12-16Canada
Diphenhydramine Hydrochloride Elixir USPElixir12.5 mgOralJamp Pharma Corporation2009-01-30Not applicableCanada
Diphenhydramine Oral LiquidLiquid12.5 mg/5mLOralRij Pharmaceutical Corporation1999-03-16Not applicableUs
Dorm-L Tab 25mgTablet25 mgOralNutribon (1986) Inc.1995-12-311996-09-30Canada
DormaxTablet50 mgOralNobel Pharm Enr.2004-06-112013-07-18Canada
DorminCapsule25 mg/1OralRandob Labs,ltd.1992-01-01Not applicableUs
Dormiphen ComprimeTablet25 mgOralLaboratoire Lalco Inc.1998-06-05Not applicableCanada
Dormiphen Extra-fort CapsuleCapsule50 mgOralLaboratoire Lalco Inc.1980-12-31Not applicableCanada
Dormiphen Extra-fort ComprimeTablet50 mgOralLaboratoire Lalco Inc.1998-06-05Not applicableCanada
Dormirax 25Tablet25 mgOralLaboratoire Riva IncNot applicableNot applicableCanada
Dormirax 50Tablet50 mgOralLaboratoire Riva IncNot applicableNot applicableCanada
Dreamol Extra StrengthTablet50 mgOralGenvion Corporation2016-04-12Not applicableCanada
Dye Free Allergy childrensLiquid12.5 mg/5mLOralQuality Choice (Chain Drug Marketing Association, Inc.)2016-02-29Not applicableUs
Dye Free Wal Dryl Allergy childrensLiquid12.5 mg/5mLOralWalgreens2015-03-31Not applicableUs
Dye-Free Adult ALLERGYSolution50 mg/20mLOralCvs Health2014-11-26Not applicableUs
Dye-free AllergyCapsule, liquid filled25 mg/1OralPura Cap Pharmaceutical Llc.2016-06-27Not applicableUs
Dye-Free ALLERGYSolution25 mg/10mLOralCvs Health2014-11-26Not applicableUs
Dye-Free AllergyCapsule, liquid filled25 mg/1OralWoonsocket Prescription Center, Incorporated2001-09-13Not applicableUs
Dye-Free Allergy ReliefCapsule, liquid filled25 mg/1OralChain Drug Marketing Association2001-09-13Not applicableUs
Dye-free Allergy ReliefCapsule, liquid filled25 mg/1OralPura Vation Pharmaceuticals Inc2013-09-122017-01-04Us
Dye-Free Wal-DrylCapsule, liquid filled25 mg/1OralWalgreen2001-09-13Not applicableUs
Each Relief EquateGel2 g/100mLTopicalWalmart2017-04-03Not applicableUs
Equaline AllergyTablet25 mg/1OralSupervalu2004-08-30Not applicableUs
Equaline AllergyCapsule25 mg/1OralSupervalu2004-08-10Not applicableUs
Equaline AllergySolution12.5 mg/5mLOralSupervalu2004-08-10Not applicableUs
Equaline Night Time Sleep AidCapsule, liquid filled25 mg/1OralSupervalu2014-03-07Not applicableUs
Equaline Night Time Sleep AidSolution50 mg/30mLOralSupervalu2013-06-28Not applicableUs
Equate Allergy ReliefTablet25 mg/1OralWalmart Stores1999-07-30Not applicableUs
Equate Allergy ReliefSolution12.5 mg/5mLOralWalmart Stores1990-08-15Not applicableUs
Equate Nighttime Sleep AidTablet25 mg/1OralWalmart Stores2000-05-16Not applicableUs
Extra Strength Allergy Formula Liquid CapsulesCapsule50 mgOralVita Health Products Inc2009-11-05Not applicableCanada
Extra Strength Allergy Formula NighttimeCapsule50 mgOralActavis Pharma CompanyNot applicableNot applicableCanada
Extra Strength Benadryl Allergy NighttimeCapsule50 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2008-05-05Not applicableCanada
Extra Strength Dormex CapletsTablet50 mgOralVita Health Products Inc2013-11-06Not applicableCanada
Extra Strength Dormex CapsulesCapsule50 mgOralVita Health Products Inc2013-11-06Not applicableCanada
Extra Strength Nighttime Allergy Liquid Gel CapsulesCapsule50 mgOralApotex CorporationNot applicableNot applicableCanada
Extra Strength Nytol QuickgelsCapsule50 mgOralMedtech Laboratories, Inc.1999-01-08Not applicableCanada
Extra Strength Nytol Tab 50mgTablet50 mgOralMedtech Laboratories, Inc.1983-12-31Not applicableCanada
Extra Strength Simply Sleep Liqui-gelsCapsule50 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Extra Strength Sleep AidTablet50 mgOralVita Health Products IncNot applicableNot applicableCanada
Extra Strength Sleep AidTablet50 mgOralPendopharm Division Of De Pharmascience Inc2007-06-01Not applicableCanada
Extra Strength Sleep Aid FastCapsule50 mgOralBanner Pharmacaps2003-11-072014-09-10Canada
Extra Strength Sleep Aid Liquid GelsCapsule50 mgOralAccucaps Industries LimitedNot applicableNot applicableCanada
EZ Nite SleepCapsule, liquid filled25 mg/1OralPreferred Plus (Kinray)2014-02-12Not applicableUs
EZ Nite SleepLiquid50 mg/30mLOralSafeway2015-06-30Not applicableUs
EZ Nite SleepCapsule, liquid filled25 mg/1OralP & L Development Of New York Corporation2013-11-30Not applicableUs
EZ Nite SleepLiquid50 mg/30mLOralKroger2015-03-31Not applicableUs
EZ Nite SleepLiquid50 mg/30mLOralDolgencorp, Inc. (Dollar General & Rexall)2013-01-01Not applicableUs
EZ Nite SleepLiquid50 mg/30mLOralP & L Development, LLC2013-01-01Not applicableUs
EZ Nite SleepLiquid50 mg/30mLOralQuality Choice (Chain Drug Marketing Association, Inc.)2015-06-30Not applicableUs
EZ Nite SleepCapsule, liquid filled25 mg/1OralKroger2014-12-31Not applicableUs
EZ Nite Sleep AidLiquid50 mg/30mLOralEQUATE (Walmart Stores, Inc.)2015-10-31Not applicableUs
EZ Nite Sleep AidLiquid50 mg/30mLOralAafes/Your Military Exchanges2015-08-31Not applicableUs
EZ Nite Sleep BerryLiquid50 mg/30mLOralExchange Select2013-11-21Not applicableUs
EZ Nite Sleep Nighttime Sleep AidCapsule, liquid filled25 mg/1OralFamily Dollar (FAMILY WELLNESS)2013-10-30Not applicableUs
EZ Nite Sleep Nighttime Sleep AidCapsule, liquid filled25 mg/1OralFamily Dollar (FAMILY WELLNESS)2014-07-31Not applicableUs
EZ Nite Sleep Nighttime Sleep-AidCapsule, liquid filled25 mg/1OralKroger2013-04-11Not applicableUs
EZ Nite Sleep Nighttime Sleep-AidCapsule, liquid filled25 mg/1OralQuality Choice (Chain Drug Marketing Association, Inc.)2013-03-11Not applicableUs
EZ Nite Sleep Nighttime Sleep-AidCapsule, liquid filled25 mg/1OralQuality Choice (Chain Drug Marketing Association, Inc.)2014-07-31Not applicableUs
First Aid Shot Therapy Allergy ReliefSolution50 mg/40mLOralFirst Aid Beverages, Inc.2016-07-01Not applicableUs
First Aid Shot Therapy Sleep AidSolution50 mg/40mLOralFirst Aid Beverages, Inc.2016-07-01Not applicableUs
Formule Allergie LiquideElixir12.5 mgOralProdemdis Enr.Not applicableNot applicableCanada
Geri-Dryl allergy reliefTablet, coated25 mg/1OralGericare Pharmaceuticals2011-09-01Not applicableUs
Good Neighbor Pharmacy allergyTablet25 mg/1OralAmerisource Bergen1991-08-30Not applicableUs
Good Neighbor Pharmacy AllergyCapsule25 mg/1OralAmerisource Bergen1989-10-15Not applicableUs
Good Neighbor Pharmacy AllergyCapsule25 mg/1OralRebel Distributors1989-10-15Not applicableUs
Good Neighbor Pharmacy Childrens AllergySolution12.5 mg/5mLOralAmerisource Bergen1989-08-15Not applicableUs
Good Neighbor Pharmacy Childrens AllergySolution12.5 mg/5mLOralLake Erie Medical Dba Quality Care Produts Llc1989-08-15Not applicableUs
Good Neighbor Pharmacy CleartimeTablet, film coated25 mg/1OralAmerisource Bergen2015-03-25Not applicableUs
Good Neighbor Pharmacy Sleep AidTablet25 mg/1OralAmerisource Bergen2001-04-14Not applicableUs
Good Neighbor Pharmacy Sleep TimeCapsule, liquid filled25 mg/1OralAmerisource Bergen2014-01-30Not applicableUs
Good Neighbor Pharmacy Sleep TimeSolution50 mg/30mLOralAmerisource Bergen2013-07-22Not applicableUs
Good Sense AllergySolution12.5 mg/5mLOralL. Perrigo Company1989-09-15Not applicableUs
Good Sense Allergy ReliefCapsule25 mg/1OralL. Perrigo Company1989-09-15Not applicableUs
Good Sense Allergy ReliefTablet25 mg/1OralL. Perrigo Company1991-08-20Not applicableUs
Good Sense Allergy ReliefCapsule25 mg/1OralProficient Rx LP1989-09-15Not applicableUs
Good Sense Nighttime Sleep AidTablet25 mg/1OralL. Perrigo Company2009-09-02Not applicableUs
Good Sense Nighttime Sleep AidTablet25 mg/1OralL. Perrigo Company2001-04-25Not applicableUs
Good Sense Sleep TimeCapsule, liquid filled25 mg/1OralL. Perrigo Company2014-02-06Not applicableUs
Good Sense Sleep TimeSolution50 mg/30mLOralL. Perrigo Company2013-07-02Not applicableUs
Handy Solutions Allergy ReliefTablet25 mg/1OralNavajo Manuracturing Company2016-10-22Not applicableUs
Harris Teeter Childrens AllergySolution12.5 mg/5mLOralHarris Teeter2015-06-24Not applicableUs
Health mart allergy childrensLiquid12.5 mg/5mLOralMc Kesson2012-01-11Not applicableUs
Health Mart Childrens Allergy ReliefSolution12.5 mg/5mLOralMc Kesson2016-03-15Not applicableUs
Health Mart Maximum Strength Sleep AidCapsule, liquid filled50 mg/1OralMc Kesson2012-04-06Not applicableUs
Health Mart Nighttime Sleep AidTablet25 mg/1OralMc Kesson2013-08-13Not applicableUs
Health Mart Z SleepSolution50 mg/30mLOralMc Kesson2013-07-16Not applicableUs
Health Mart z-sleepCapsule, liquid filled25 mg/1OralMc Kesson2014-01-31Not applicableUs
Healthy Accents AllergySolution12.5 mg/5mLOralDza Brands,2008-04-01Not applicableUs
Healthy Accents Allergy ReliefCapsule25 mg/1OralDza Brands,2008-01-29Not applicableUs
Healthy Accents Allergy ReliefTablet25 mg/1OralDza Brands,2008-01-29Not applicableUs
Healthy Accents Nighttime Sleep AidTablet25 mg/1OralDza Brands,2008-02-24Not applicableUs
Healthy Accents SleeptimeCapsule, liquid filled25 mg/1OralDza Brands,2016-05-11Not applicableUs
Healthy Accents SleeptimeSolution50 mg/30mLOralDza Brands,2014-05-09Not applicableUs
Helath Mart Childrens allergy relief dye freeLiquid12.5 mg/5mLOralMc Kesson2014-09-09Not applicableUs
Help I Can't SleepTablet25 mgOralHelp Remedies, Inc.Not applicableNot applicableCanada
Help I cant SleepTablet25 mg/1OralHelp Remedies, Inc.2009-07-01Not applicableUs
HistaprinTablet25 mg/1OralNor Med2009-01-01Not applicableUs
InsomnalTablet50 mgOralTeva2011-02-14Not applicableCanada
Insomnal Cap 25mgCapsule25 mgOralWelcker Lyster Ltd., Division Of Technilab Inc.1979-12-312004-08-03Canada
Insomnal DSCapsule50 mgOralRougier Pharma Division Of Ratiopharm Inc1996-12-312015-10-01Canada
Itch ReliefLiquid20.3 g/LTopicalSafetec Of America Inc2013-05-02Not applicableUs
Itch ReliefSpray2 g/100mLTopicalWater Jel Technologies2010-09-25Not applicableUs
Itch ReliefLiquid20.3 g/LTopicalCintas First Aid & Safety2013-05-13Not applicableUs
Itch Relief CreamCream2 %TopicalPharmetics (2011) Inc.Not applicableNot applicableCanada
Itch Relif CvsGel2 g/100mLTopicalCvs Health2014-02-14Not applicableUs
Jack & Jill BedtimeLiquid6.25 mgOralThe Buckley's Company2000-08-082016-08-02Canada
Jack & Jill Thin Strips Cough & ColdStrip12.5 mgOralThe Buckley's Company2005-08-082010-06-21Canada
Jamp Diphenhydramine Children's SyrupSyrup6.25 mgOralJamp Pharma CorporationNot applicableNot applicableCanada
Junior Strength Allergy FormulaTablet12.5 mgOralTeva2010-12-10Not applicableCanada
Junior Strength Allergy TabletsTablet12.5 mgOralTanta Pharmaceuticals IncNot applicableNot applicableCanada
Kids-EEZE AllergyTablet, orally disintegrating12.5 mg/1OralPro Phase Labs, Inc.2010-09-01Not applicableUs
Leader AllergyTablet25 mg/1OralCardinal Health2014-12-22Not applicableUs
Leader allergyTablet25 mg/1OralCardinal Health1992-05-11Not applicableUs
Leader AllergyCapsule25 mg/1OralCardinal Health2015-01-02Not applicableUs
Leader AllergyCapsule25 mg/1OralCardinal Health1990-04-15Not applicableUs
Leader Childrens AllergySolution12.5 mg/5mLOralCardinal Health1990-05-15Not applicableUs
Leader Maximum Strength Sleep AidCapsule, liquid filled50 mg/1OralCardinal Health2012-06-05Not applicableUs
LEADER Nighttime Sleep-AidLiquid50 mg/30mLOralCardinal Health2017-01-17Not applicableUs
Leader Restfully SleepTablet25 mg/1OralCardinal Health2000-09-15Not applicableUs
Leader Sleep AidSolution50 mg/30mLOralCardinal Health2017-08-04Not applicableUs
Leader SleepTimeSolution50 mg/30mLOralCardinal Health2013-10-11Not applicableUs
Leader SleepTimeCapsule, liquid filled25 mg/1OralCardinal Health2013-12-02Not applicableUs
Lil Drug Store Nighttime Sleep-AidTablet25 mg/1OralLil' Drug Store Products, Inc.2011-06-022017-02-02Us
Lil Drug Store Nighttime Sleep-AidTablet25 mg/1OralLil' Drug Store Products, Inc.2011-06-022017-02-02Us
Lil Drug Store Products Allergy AntihistamineTablet25 mg/1OralLil' Drug Store Products, Inc.2015-01-10Not applicableUs
Lil Drug Store Products Allergy AntihistamineTablet25 mg/1OralLil' Drug Store Products, Inc.2015-01-10Not applicableUs
Lil Drug Store Products Allergy AntihistamineTablet25 mg/1OralLil' Drug Store Products, Inc.2015-01-10Not applicableUs
MAXIMUM STRENGTH Nighttime Sleep AidCapsule, liquid filled50 mg/1OralPura Cap Pharmaceutical Llc.2016-07-12Not applicableUs
Medique DiphenTablet, film coated25 mg/1OralUnifirst First Aid2012-01-01Not applicableUs
Medique DiphenTablet, film coated25 mg/1OralUnifirst First Aid2012-01-01Not applicableUs
Multi-symptom AllergyCapsule25 mg/1OralMc Kesson (Health Mart)2012-02-14Not applicableUs
Nadryl 25mgTablet25 mgOralLaboratoire Riva Inc2002-02-14Not applicableCanada
Nadryl 50mgTablet50 mgOralLaboratoire Riva Inc2002-02-14Not applicableCanada
NaraminSolution12.5 mg/5mLOralNational Pharma Industries Inc2014-05-28Not applicableUs
Neocitran Thin Strips Nighttime CoughLozenge25 mgOralNovartis2004-11-192013-07-31Canada
Night Cough Liquid FastgelsCapsule25 mgOralVita Health Products Inc2008-10-14Not applicableCanada
Night Time Sleep AidCapsule, liquid filled25 mg/1OralHarmon Stores2015-02-28Not applicableUs
Night Time Sleep AidCapsule50 mg/1OralHyvee2014-02-01Not applicableUs
Night Time Sleep AidSolution50 mg/30mLOralHyvee2013-07-08Not applicableUs
Night Time Sleep AidLiquid50 mg/30mLOralDolgencorp, Inc. (Dollar General & Rexall)2015-03-31Not applicableUs
Night Time Sleep AidCapsule, liquid filled25 mg/1OralPura Cap Pharmaceutical Llc.2016-05-05Not applicableUs
Night Time Sleep-aidLiquid50 mg/30mLOralDiscount Drug Mart2013-12-10Not applicableUs
Nightime Sleep AidCapsule, liquid filled50 mg/1OralVelocity Pharma2014-03-31Not applicableUs
Nightime Sleep AidCapsule, liquid filled50 mg/1OralAgile Pharmachem2014-03-31Not applicableUs
NighttimeTablet25 mg/1OralWestern Family Foods2001-01-28Not applicableUs
Nighttime AllergyTablet50 mgOralPharmetics (2011) Inc.Not applicableNot applicableCanada
Nighttime Allergy Relief Extra StrengthTablet50 mg/1OralMeijer2014-06-30Not applicableUs
Nighttime Allergy Relief Extra StrengthTablet50 mg/1OralTopcare (Topco Associates Llc)2014-07-31Not applicableUs
Nighttime Liquigel Sleep-aidCapsule25 mgOralActavis Pharma CompanyNot applicableNot applicableCanada
Nighttime SleepTablet, film coated25 mg/1OralSafeway2000-06-10Not applicableUs
Nighttime Sleep AidSolution50 mg/30mLOralMeijer Distribution2014-12-04Not applicableUs
Nighttime Sleep AidTablet25 mg/1OralWin Co Foods, Llc,2000-06-10Not applicableUs
Nighttime Sleep AidTablet25 mg/1OralChain Drug Consortium2010-07-08Not applicableUs
Nighttime Sleep AidCapsule25 mgOralApotex Corporation2014-01-24Not applicableCanada
Nighttime Sleep AidCapsule, liquid filled25 mg/1OralWin Co Foods, Llc,2014-12-31Not applicableUs
Nighttime Sleep AidTablet, coated25 mg/1OralHealth Life Of Usa2012-05-12Not applicableUs
Nighttime Sleep AidTablet25 mg/1OralH.E.B.2009-10-09Not applicableUs
Nighttime Sleep AidCapsule, liquid filled50 mg/1OralWoonsocket Prescription Center, Incorporated2004-04-08Not applicableUs
Nighttime Sleep AidTablet25 mg/1OralKroger2001-02-05Not applicableUs
Nighttime Sleep AidSolution50 mg/30mLOralH.E.B.2013-10-30Not applicableUs
Nighttime Sleep AidTablet25 mg/1OralKroger2012-11-02Not applicableUs
Nighttime Sleep AidSolution50 mgOralJuno Otc IncNot applicableNot applicableCanada
Nighttime Sleep AidCapsule50 mg/1OralSuper Valu (Equaline)2012-01-03Not applicableUs
Nighttime Sleep AidTablet25 mg/1OralChain Drug Marketing Association2007-06-25Not applicableUs
Nighttime Sleep AidCapsule, liquid filled25 mg/1OralSafeway2013-05-31Not applicableUs
Nighttime Sleep AidCapsule50 mg/1OralGood Sense (Geiss, Destin & Dunn, Inc.)2013-04-15Not applicableUs
Nighttime Sleep AidLiquid50 mg/30mLOralCare One (American Sales Company)2015-06-30Not applicableUs
Nighttime Sleep AidCapsule, liquid filled25 mg/1OralH.E.B.2013-09-30Not applicableUs
Nighttime SLEEP AIDCapsule, liquid filled25 mg/1OralPura Cap Pharmaceutical Llc.2016-06-27Not applicableUs
Nighttime Sleep AidTablet25 mg/1OralSuper Valu (Equaline)2012-10-31Not applicableUs
Nighttime Sleep AidTablet, film coated25 mg/1OralSupervalu2000-06-10Not applicableUs
Nighttime Sleep AidTablet, film coated25 mg/1OralMc Kesson (Health Mart)2000-06-10Not applicableUs
Nighttime Sleep AidCapsule, liquid filled25 mg/1OralASSURED / DOLLAR TREE (Greenbrier International, Inc.)2017-05-31Not applicableUs
Nighttime Sleep AidTablet, film coated25 mg/1OralTarget Corporation.2000-06-10Not applicableUs
Nighttime Sleep AidTablet, film coated25 mg/1OralSunmark (Mckesson)2000-06-10Not applicableUs
Nighttime Sleep AidCapsule50 mg/1OralValu Merchandisers Company (Best Choice)2010-07-26Not applicableUs
Nighttime Sleep AidTablet25 mg/1OralWestern Family Foods2010-07-12Not applicableUs
Nighttime Sleep AidTablet25 mg/1OralWe Care Distributor Inc.2016-02-04Not applicableUs
Nighttime Sleep AidCapsule, liquid filled25 mg/1OralFred's2014-11-30Not applicableUs
Nighttime Sleep AidCapsule, liquid filled25 mg/1OralMeijer Distribution2016-02-07Not applicableUs
Nighttime Sleep AidTablet25 mg/1OralEQUATE (Walmart Stores, Inc.)2013-09-30Not applicableUs
Nighttime Sleep AidTablet25 mg/1OralAvema Pharma Solutions2011-01-162017-04-14Us
Nighttime Sleep AidCapsule, liquid filled25 mg/1OralNash Finch Company (Our Family)2013-11-30Not applicableUs
Nighttime Sleep AidCapsule, liquid filled25 mg/1OralPura Cap Pharmaceutical Llc.2016-07-26Not applicableUs
Nighttime Sleep AidLiquid50 mg/30mLOralFred's2013-10-23Not applicableUs
Nighttime Sleep AidCapsule, liquid filled25 mg/1OralH.E.B.2014-12-31Not applicableUs
Nighttime Sleep AidCapsule, liquid filled50 mg/1OralPura Vation Pharmaceuticals Inc2013-04-152017-01-04Us
Nighttime Sleep AidTablet, film coated25 mg/1OralCvs Health2000-06-10Not applicableUs
Nighttime Sleep AidCapsule50 mg/1OralChain Drug Consortium2010-07-08Not applicableUs
Nighttime Sleep AidCapsule, liquid filled25 mg/1OralHyvee2014-11-24Not applicableUs
Nighttime Sleep AidCapsule, liquid filled50 mg/1OralTopco Associates2016-07-19Not applicableUs
Nighttime Sleep AidCapsule, liquid filled50 mg/1OralCvs Health2015-03-01Not applicableUs
Nighttime sleep aidCapsule, liquid filled50 mg/1OralValu Merchandisers Company (Best Choice)2014-02-01Not applicableUs
Nighttime Sleep AidCapsule, liquid filled50 mg/1OralPura Cap Pharmaceutical Llc.2016-06-01Not applicableUs
Nighttime Sleep AidCapsule50 mg/1OralWestern Family Foods2010-07-01Not applicableUs
Nighttime Sleep Aid Alcohol FreeLiquid50 mg/30mLOralWalmart Stores2016-09-12Not applicableUs
Nighttime Sleep Aid LiquidSolution50 mgOralPerrigo International2015-05-13Not applicableCanada
Nighttime Sleep Aid Maximum StrengthCapsule50 mg/1OralNash Finch Company (Our Family)2014-02-01Not applicableUs
Nighttime Sleep Aid Maximum StrengthCapsule, liquid filled50 mg/1OralDolgencorp, Inc. (Dollar General & Rexall)2014-02-01Not applicableUs
Nighttime Sleep Aid maximum strengthCapsule50 mg/1OralEQUATE (Walmart Stores, Inc.)2010-07-06Not applicableUs
Nighttime Sleep Aid Maximum StrengthCapsule, liquid filled50 mg/1OralP & L Development, LLC2011-09-022016-12-31Us
Nighttime Sleep Aid maximum strengthCapsule50 mg/1OralLIVE BETTER (The Great Atlantic & Pacific Tea Company)2010-07-26Not applicableUs
Nighttime Sleep Aid Maximum StrengthCapsule50 mg/1OralWestern Family Foods2014-02-01Not applicableUs
Nighttime Sleep Aid Maximum StrengthCapsule50 mg/1OralCvs Health2014-02-01Not applicableUs
Nighttime Sleep Aid Maximum StrengthCapsule50 mg/1OralChain Drug Consortium2014-02-01Not applicableUs
Nighttime sleep aid Maximum StrengthCapsule, liquid filled50 mg/1OralGood Sense (Geiss, Destin & Dunn, Inc.)2014-02-01Not applicableUs
NightTime Sleep Aid Maximum StrengthCapsule, liquid filled50 mg/1OralLIVE BETTER (The Great Atlantic & Pacific Tea Company)2014-02-01Not applicableUs
Nighttime Sleep Aid Maximum StrengthCapsule50 mg/1OralMc Kesson (Health Mart)2014-02-01Not applicableUs
Nighttime Sleep Aid Maximum StrengthCapsule50 mg/1OralWalgreens2014-02-01Not applicableUs
NIGHTTIME SLEEP AID Maximum StrengthCapsule, liquid filled50 mg/1OralEQUATE (Walmart Stores, Inc.)2013-10-31Not applicableUs
Nighttime Sleep Aid Maximum StrengthTablet, film coated50 mg/1OralWalgreen2016-07-31Not applicableUs
Nighttime Sleep Aid Non Habit FormingCapsule, liquid filled25 mg/1OralFred's2013-04-11Not applicableUs
Nighttime Sleep Aid SoftgelsCapsule, gelatin coated25 mg/1OralCvs Health2015-07-14Not applicableUs
Nighttime Sleep EasyTablet25 mg/1OralP And L Development Of New York Corporation (Ready In Case)2012-12-04Not applicableUs
Nighttime Sleep-aidLiquid50 mgOralTeva2015-02-12Not applicableCanada
Nighttime Sleep-AidCapsule, liquid filled25 mg/1OralPura Cap Pharmaceutical Llc.2015-05-26Not applicableUs
Nighttime Sleep-AidTablet25 mg/1OralWoonsocket Prescription Center, Incorporated2013-05-072017-02-26Us
Nighttime Sleep-AidLiquid50 mg/30mLOralDe Moulas Market Basket2013-09-19Not applicableUs
Nighttime Sleep-aidTablet25 mg/1OralGericare Pharmaceuticals2004-01-01Not applicableUs
Nighttime Sleep-AidCapsule, liquid filled25 mg/1OralLil' Drug Store Products, Inc.2014-09-05Not applicableUs
Nighttime Sleep-AidCapsule25 mg/1OralSafeway2014-12-31Not applicableUs
Nighttime Sleep-Aid Maximum StrengthCapsule50 mg/1OralSMART SENSE (Kmart)2013-03-31Not applicableUs
Nighttime Sleep-Aid SoftgelCapsule, liquid filled50 mg/21OralAi Ping Pharmaceutical, Inc.2015-01-31Not applicableUs
Nighttime SleepaidCapsule, gelatin coated50 mg/21OralKareway Product, Inc.2014-10-22Not applicableUs
Nighttime SnoozeCapsule25 mgOralVita Health Products IncNot applicableNot applicableCanada
Nite Time Sleep Aid LiquidGelsCapsule, liquid filled25 mg/1OralDolgencorp, Inc. (Dollar General)2013-04-11Not applicableUs
North AntihistamineTablet25 mg/1OralNorth Safety Products2011-12-02Not applicableUs
NytolTablet25 mg/1OralMedtech Laboratories, Inc.2012-06-01Not applicableUs
Nytol Extra Strength Sleep Aid Caplet 50mgTablet50 mgOralMedtech Laboratories, Inc.1991-12-31Not applicableCanada
Nytol QuickCapsTablet, film coated25 mg/1OralGlaxo Smith Kline Consumer Heathcare Lp2011-08-12Not applicableUs
Nytol Tablet 25mgTablet25 mgOralMedtech Laboratories, Inc.1979-12-31Not applicableCanada
On The GO-DoseSolution12.5 mg/5mLOralPerfect Measure Llc2014-05-28Not applicableUs
Pdp-diphenhydramineCapsule25 mgOralPendopharm Division Of De Pharmascience Inc1990-12-31Not applicableCanada
Pdp-diphenhydramineCapsule50 mgOralPendopharm Division Of De Pharmascience Inc1990-12-31Not applicableCanada
Pediacare Childrens AllergyLiquid12.5 mg/5mLOralBlacksmith Brands, Inc.2009-10-29Not applicableUs
Pediacare Childrens AllergyLiquid12.5 mg/5mLOralBlacksmith Brands, Inc.2010-02-01Not applicableUs
PharbedrylCapsule25 mg/1OralContract Pharmacy Services Pa2006-10-11Not applicableUs
PharbedrylCapsule25 mg/1OralA S Medication Solutions2006-10-112017-06-20Us
PharbedrylCapsule50 mg/1OralContract Pharmacy Services Pa2006-10-11Not applicableUs
PharbedrylCapsule25 mg/1OralA S Medication Solutions2006-10-112017-06-20Us
PharbedrylCapsule50 mg/1OralPharbest Pharmaceuticals, Inc.2006-10-11Not applicableUs
PharbedrylCapsule25 mg/1OralA S Medication Solutions2006-10-112017-06-20Us
PharbedrylCapsule25 mg/1OralPharbest Pharmaceuticals, Inc.2006-10-11Not applicableUs
PharbedrylCapsule50 mg/1OralA S Medication Solutions2006-10-112017-06-20Us
Plus PharmaTablet, film coated25 mg/1OralGemini Pharmaceuticals, Inc. dba Plus Pharma2015-06-12Not applicableUs
PMS-diphenhydramine Elixir 2.5mg/mlElixir2.5 mgOralPharmascience Inc1990-12-31Not applicableCanada
Preferred Plus Complete Allergy MedicineCapsule25 mg/1OralKinray2013-05-07Not applicableUs
Premier Value Nighttime Sleep Aid SoftgelsCapsule, gelatin coated50 mg/21OralChain Drug Consortium2014-11-14Not applicableUs
Premier Value Nighttime Sleep-Aid Liquid Sleep-AidLiquid50 mg/30mLOralChain Drug Consortium2012-12-10Not applicableUs
Premier Value Sleep-AidCapsule50 mg/1OralChain Drug Consortium2013-05-31Not applicableUs
Q-drylCapsule25 mg/1OralQualitest2007-05-242018-05-31Us
Qdryl AllergySolution12.5 mg/5mLOralPreferreed Pharmaceuticals Inc.1997-12-01Not applicableUs
Qdryl AllergySolution12.5 mg/5mLOralLake Erie Medical Dba Quality Care Produts Llc1997-12-01Not applicableUs
Qdryl AllergySolution12.5 mg/5mLOralAtlantic Biologicals Corp.1997-12-01Not applicableUs
Qdryl AllergySolution12.5 mg/5mLOralA S Medication Solutions1997-12-012017-06-20Us
Qdryl AllergySolution12.5 mg/5mLOralRemedy Repack2015-03-042017-03-16Us
Qdryl AllergySolution12.5 mg/5mLOralA S Medication Solutions1997-12-012019-10-31Us
Qdryl AllergySolution12.5 mg/5mLOralQualitest1997-12-012019-10-31Us
Quenalin CoughSyrup12.5 mg/5mLOralQualitest1993-12-032016-11-15Us
Regular Strength Dormex CapsulesCapsule25 mgOralVita Health Products Inc2013-11-06Not applicableCanada
Regular Strength Sleep AidCapsule25 mgOralVita Health Products Inc2011-03-31Not applicableCanada
Rest SimplyTablet, film coated25 mg/1OralNash Finch2000-06-10Not applicableUs
Rest SimplyTablet, coated25 mg/1OralChain Drug Marketing Association2014-06-13Not applicableUs
Rest SimplyTablet, film coated25 mg/1OralGreat Lakes Wholesale, Marketing, and Sales, Inc.2000-06-10Not applicableUs
Rest SimplyTablet, coated25 mg/1OralFreds, Inc.2008-09-01Not applicableUs
Rest SimplyTablet, film coated25 mg/1OralChain Drug Consortium2000-06-10Not applicableUs
Restfully SleepTablet, film coated25 mg/1OralCardinal Health2000-06-102020-08-10Us
Rexall Childrens AllergyLiquid12.5 mg/5mLOralDolgencorp2013-07-26Not applicableUs
Rexall Sleep AidTablet25 mg/1OralDolgencorp2010-09-29Not applicableUs
Rite Aid Maximum Strength Itch ReliefGel20.5 mg/mLTopicalRite Aid2011-08-10Not applicableUs
Rugby DiphenhistTablet, film coated25 mg/1OralRugby2014-12-13Not applicableUs
SedamoTablet25 mgOralViva Pharmaceutical Inc.Not applicableNot applicableCanada
Sedicin Tablets 25mgTablet25 mgOralCrombie Kennedy Nasmark Inc.1960-12-312000-07-19Canada
Select Brand Extra Strength Itch StoppingGel.2 g/10mLTopicalSelect Brand2012-07-11Not applicableUs
Select Health Allergy Relief CherryLiquid12.5 mg/5mLOralAxcentria Pharmaceuticals, Llc2011-09-01Not applicableUs
ShopRite Allergy ReliefCapsule25 mg/1OralWakfern Food Corporation2016-09-12Not applicableUs
ShopRite Allergy ReliefTablet25 mg/1OralWakfern Food Corporation2016-09-13Not applicableUs
ShopRite Childrens AllergySolution12.5 mg/5mLOralWakfern Food Corporation2016-01-11Not applicableUs
ShopRite Sleep AidSolution50 mg/30mLOralWakfern Food Corporation2013-07-17Not applicableUs
Siladryl Allergy MedicineLiquid12.5 mg/5mLOralSilarx Pharmaceuticals, Inc.1997-01-01Not applicableUs
Siladryl Allergy MedicineLiquid12.5 mg/5mLOralRebel Distributors1997-01-01Not applicableUs
SilphenSyrup12.5 mg/5mLOralSilarx Pharmaceuticals, Inc.1993-12-03Not applicableUs
Simply Right Diphenhydramine Hydrochloride Allergy ReliefTablet25 mg/1OralSam's West, Inc2012-01-27Not applicableUs
Simply SleepTablet25 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2000-03-292016-01-22Canada
Simply SleepTablet, film coated25 mg/1OralJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2004-02-01Not applicableUs
Simply Sleep Liqui-gelsCapsule25 mgOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
SleepTablet25 mg/1OralSalado Sales, Inc.1990-04-10Not applicableUs
Sleep AidTablet25 mg/1OralCvs Health2000-10-03Not applicableUs
Sleep AidCapsule, liquid filled50 mg/1OralLnk International, Inc.2015-03-01Not applicableUs
Sleep AidTablet25 mg/1OralAllegiant Health2015-03-03Not applicableUs
Sleep AidCapsule, liquid filled25 mg/1OralPura Vation Pharmaceuticals Inc2013-04-152017-01-04Us
Sleep AidTablet, film coated25 mg/1OralCardinal Health2000-06-10Not applicableUs
Sleep AidCapsule50 mg/1OralRite Aid2017-02-28Not applicableUs
Sleep AidTablet25 mg/1OralMedicine Shoppe International2001-06-19Not applicableUs
Sleep AidTablet25 mg/1OralMeijer Distribution2004-10-17Not applicableUs
Sleep AidTablet, film coated25 mg/1OralHarmon Store Inc.2013-07-01Not applicableUs
Sleep AidTablet, film coated25 mg/1OralLnk International, Inc.2000-06-10Not applicableUs
Sleep AidTablet, film coated25 mg/1OralRite Aid2000-06-10Not applicableUs
Sleep AidTablet25 mg/1OralChain Drug Consortium2010-07-12Not applicableUs
Sleep AidCapsule, liquid filled25 mg/1OralPura Cap Pharmaceutical Llc.2016-07-20Not applicableUs
Sleep AidCapsule, liquid filled50 mg/1OralCardinal Health2015-03-01Not applicableUs
Sleep AidTablet25 mg/1OralKareway Product, Inc.2011-08-18Not applicableUs
Sleep AidTablet25 mg/1OralSMART SENSE (Kmart)2014-03-31Not applicableUs
Sleep AidCapsule50 mg/1OralKroger2010-07-12Not applicableUs
Sleep AidTablet50 mgOralVita Health Products Inc1997-06-10Not applicableCanada
Sleep AidTablet, film coated25 mg/1OralHyvee2001-02-23Not applicableUs
Sleep AidTablet25 mg/1OralChain Drug Consortium1998-11-07Not applicableUs
Sleep AidTablet25 mg/1OralRite Aid1990-04-10Not applicableUs
Sleep AidCapsule, liquid filled50 mg/1OralLnk International, Inc.2004-04-08Not applicableUs50844 0293 19 nlmimage10 963bcb4e
Sleep AidTablet, film coated25 mg/1OralHarmon Store Inc.2000-06-10Not applicableUs
Sleep AidTablet, film coated25 mg/1OralMeijer Distribution2000-06-10Not applicableUs
Sleep AidCapsule, liquid filled25 mg/1OralLnk International, Inc.2015-02-28Not applicableUs
Sleep AidSolution50 mg/30mLOralRite Aid2016-07-07Not applicableUs
Sleep AidCapsule, liquid filled25 mg/1OralCardinal Health2015-02-28Not applicableUs
Sleep AidTablet25 mg/1OralValu Merchandisers Company (Best Choice)2014-04-30Not applicableUs
Sleep AidTablet25 mg/1OralNavarro Discount Pharmacies, LLC2013-02-01Not applicableUs
Sleep AidTablet, film coated25 mg/1OralRite Aid2015-07-24Not applicableUs
Sleep AidTablet25 mg/1OralPublix Supermarkets, Inc.2001-07-24Not applicableUs
Sleep AidCapsule50 mg/1OralFred's2014-02-01Not applicableUs
Sleep Aid (extra Strength) Tab 50mgTablet50 mgOralTanta Pharmaceuticals Inc1997-03-04Not applicableCanada
Sleep Aid (regular Strength) Tab 25mgTablet25 mgOralTanta Pharmaceuticals Inc1993-12-31Not applicableCanada
Sleep Aid CapletsTablet25 mgOralPharmetics (2011) Inc.Not applicableNot applicableCanada
Sleep Aid Dye-Free NIghttimeTablet, film coated25 mg/1OralWalgreen2013-07-01Not applicableUs
Sleep Aid Extra StrengthCapsule50 mgOralApotex CorporationNot applicableNot applicableCanada
Sleep Aid Extra StrengthCapsule50 mgOralPharmetics (2011) Inc.Not applicableNot applicableCanada
Sleep Aid Liquid FastgelsCapsule50 mgOralVita Health Products Inc2001-09-01Not applicableCanada
Sleep Aid Liquid GelsCapsule25 mgOralAccucaps Industries LimitedNot applicableNot applicableCanada
Sleep Aid Liquid GelsCapsule50 mgOralPerrigo International2001-08-222006-05-15Canada
Sleep Aid Maximum StrengthCapsule50 mg/1OralSuper Valu (Equaline)2014-02-01Not applicableUs
Sleep Aid Maximum StrengthCapsule50 mg/1OralP & L Development, LLC2014-02-01Not applicableUs
Sleep Aid Maximum StrengthCapsule50 mg/1OralTopcare (Topco Associates Llc)2013-05-31Not applicableUs
Sleep Aid maximum strengthCapsule50 mg/1OralCare One (American Sales Company)2010-07-01Not applicableUs
Sleep Aid Maximum StrengthCapsule, liquid filled50 mg/1OralGreenbrier International, Inc.2004-04-08Not applicableUs
Sleep Aid Maximum StrengthCapsule50 mg/1OralSelect Brand Dist.2014-04-30Not applicableUs
Sleep Aid Maximum StrengthCapsule, liquid filled50 mg/1OralSafeway2014-02-01Not applicableUs
Sleep Aid Maximum StrengthCapsule50 mg/1OralKroger2014-02-01Not applicableUs
Sleep Aid Maximum StrengthCapsule, liquid filled50 mg/1OralSam's West, Inc2014-02-01Not applicableUs
Sleep Aid Maximum StrengthCapsule, liquid filled50 mg/1OralMeijer2014-02-01Not applicableUs
Sleep Aid maximum strengthCapsule50 mg/1OralSunmark (Mckesson)2010-07-09Not applicableUs
Sleep Aid Maximum StrengthCapsule, liquid filled50 mg/1OralSMART SENSE (Kmart)2014-02-01Not applicableUs
Sleep Aid Maximum StrengthCapsule50 mg/1OralCardinal Health (Leader) 497812014-02-01Not applicableUs
Sleep Aid Maximum StrengthCapsule, liquid filled50 mg/1OralTopcare (Topco Associates Llc)2014-02-01Not applicableUs
Sleep Aid Maximum StrengthCapsule50 mg/1OralCare One (American Sales Company)2014-02-01Not applicableUs
Sleep Aid Maximum StrengthCapsule50 mg/1OralTarget Corporation.2014-02-01Not applicableUs
Sleep Aid Maximum StrengthCapsule50 mg/1OralASSURED / DOLLAR TREE (Greenbrier International, Inc.)2014-02-01Not applicableUs
Sleep Aid Maximum StrengthCapsule50 mg/1OralH.E.B.2014-05-30Not applicableUs
Sleep Aid maximum strengthCapsule, liquid filled50 mg/1OralEQUATE (Walmart Stores, Inc.)2014-02-01Not applicableUs
Sleep aid Maximum StrengthCapsule, liquid filled50 mg/1OralQuality Choice (Chain Drug Marketing Association, Inc.)2014-02-01Not applicableUs
Sleep Aid Maximum StrengthCapsule, liquid filled50 mg/1OralSafeway2013-04-30Not applicableUs
Sleep Aid Maximum StrengthCapsule, liquid filled50 mg/1OralGreenbrier International, Inc.2015-03-01Not applicableUs
Sleep Aid Maximum StrengthCapsule50 mg/1OralDolgencorp, Inc. (Dollar General & Rexall)2014-02-01Not applicableUs
Sleep Aid Maximum StrengthCapsule50 mg/1OralSunmark (Mckesson)2014-02-01Not applicableUs
Sleep Aid Maximum StrengthCapsule50 mg/1OralHarris Teeter2015-02-28Not applicableUs
Sleep Aid Maximum Strength NighttimeCapsule, liquid filled50 mg/1OralWin Co Foods, Llc,2014-12-31Not applicableUs
Sleep Aid NightTimeLiquid50 mg/30mLOralTarget Corporation.2016-07-31Not applicableUs
Sleep Aid NightTimeCapsule, liquid filled25 mg/1OralP & L Development, LLC2016-03-31Not applicableUs
Sleep Aid NightTimeTablet, film coated25 mg/1OralWalmart Stores2015-07-24Not applicableUs
Sleep Aid NighttimeCapsule, liquid filled25 mg/1OralTarget Corporation.2015-02-28Not applicableUs
Sleep Aid NightTimeLiquid50 mg/30mLOralFamily Dollar (FAMILY WELLNESS)2017-07-31Not applicableUs
Sleep Aid NighttimeTablet25 mg/1OralCvs Health2013-08-15Not applicableUs
Sleep Aid NighttimeTablet, film coated25 mg/1OralWalmart Stores2000-06-10Not applicableUs
Sleep Aid NighttimeTablet, film coated25 mg/1OralWalgreen2000-06-10Not applicableUs
Sleep Aid NightTimeTablet25 mg/1OralTarget Corporation.2016-07-31Not applicableUs
Sleep Aid NighttimeTablet, film coated25 mg/1OralGreenbrier International, Inc.2000-06-10Not applicableUs
Sleep Aid NighttimeCapsule50 mg/1OralFamily Dollar (FAMILY WELLNESS)2014-02-01Not applicableUs
Sleep Aid NighttimeTablet, film coated25 mg/1OralL&R Distributors, Inc.2000-06-10Not applicableUs
Sleep Aid NightTimeCapsule, liquid filled25 mg/1OralWalmart Stores2015-02-28Not applicableUs
Sleep Aid NightTimeTablet25 mg/1OralFamily Dollar (FAMILY WELLNESS)2016-07-31Not applicableUs
Sleep Aid NightTimeLiquid50 mg/30mLOralWin Co Foods, Llc,2016-06-30Not applicableUs
Sleep Aid NightTimeLiquid50 mg/30mLOralP & L Development, LLC2016-08-31Not applicableUs
Sleep Aid NighttimeTablet, film coated25 mg/1OralBetter Living Brands2000-06-10Not applicableUs
Sleep Aid NighttimeTablet, film coated25 mg/1OralFamily Dollar Services2000-06-10Not applicableUs
Sleep Aid NighttimeTablet25 mg/1OralPld Acquisitions Llc Dba Avéma Pharma Solutions2010-01-02Not applicableUs
Sleep Aid NighttimeCapsule, liquid filled25 mg/1OralArmy + Air Force Exchange Service2015-02-28Not applicableUs
Sleep Aid NighttimeTablet25 mg/1OralH.E.B.2014-08-31Not applicableUs
Sleep Aid Nite TimeTablet, film coated25 mg/1OralDolgencorp2000-06-102017-05-20Us
Sleep Aid Regular StrengthTablet25 mg/1OralGood Sense (Geiss, Destin & Dunn, Inc.)2014-02-28Not applicableUs
Sleep Aid Regular strengthTablet25 mg/1OralGeiss, Destin & Dunn, Inc (Goodsense)2010-08-03Not applicableUs
Sleep EasyTablet, coated25 mg/1OralAvema Pharma Solutions2010-01-022017-04-14Us
Sleep Eze D Caplet 25mgTablet25 mgOralWhitehall Robins Inc.1993-12-311997-08-07Canada
Sleep Eze D Extra Strength Cap 50mgCapsule50 mgOralWhitehall Robins Inc.1993-12-311997-08-07Canada
Sleep Eze D Extra Strength Caplet 50mgTablet50 mgOralWhitehall Robins Inc.1993-12-311997-08-07Canada
Sleep II Nighttime Sleep AidTablet25 mg/1OralWalgreen1990-04-10Not applicableUs
Sleep Nighttime Sleep AidTablet25 mg/1OralWestern Family Foods2014-02-28Not applicableUs
Sleep original formulaTablet25 mg/1OralValu Merchandisers Company (Best Choice)2010-07-16Not applicableUs
Sleep TabsTablet25 mg/1OralL&R Distributors, Inc.1990-04-10Not applicableUs
Sleep TabsTablet25 mg/1OralMajor1992-12-25Not applicableUs
Sleep Tabs For Nighttime useTablet25 mg/1OralAllegiant Health2015-04-28Not applicableUs
Sleep TimeCapsule, liquid filled25 mg/1OralHyvee2014-02-01Not applicableUs
Sleep TimeLiquid50 mg/30mLOralHyvee2013-07-08Not applicableUs
Sleep TimeSolution50 mg/30mLOralLidl Us Llc2017-05-18Not applicableUs
Sleep- Aid NighttimeCapsule25 mg/1OralCvs Health2016-07-31Not applicableUs
Sleep-aidTablet25 mg/1OralInternational Laboratories, Llc2016-05-27Not applicableUs
Sleep-AidTablet25 mg/1OralArmy + Air Force Exchange Service1990-04-10Not applicableUs
Sleep-aid Extra StrengthTablet50 mgOralTeva1997-02-06Not applicableCanada
Sleep-Aid Maximum StrengthCapsule50 mg/1OralASSURED / DOLLAR TREE (Greenbrier International, Inc.)2010-07-06Not applicableUs
Sleep-Aid Maximum StrengthCapsule50 mg/1OralFred's2013-03-15Not applicableUs
Sleep-Aid NighttimeTablet, film coated25 mg/1OralCvs Health2015-07-24Not applicableUs
Sleep-Aid Regular StrengthTablet25 mg/1OralCvs Health1990-04-10Not applicableUs
Sleep-ezeTablet25 mgOralPrestige Brands Inc2010-08-03Not applicableCanada
Sleep-eze D Extra Strength CapsulesCapsule50 mgOralMedtech Laboratories, Inc.1998-08-072014-03-20Canada
Sleep-eze Extra Strength CapletsTablet50 mgOralMedtech Laboratories, Inc.1997-11-12Not applicableCanada
Sleep-eze Extra Strength GelcapsCapsule50 mgOralMedtech Laboratories, Inc.1999-12-14Not applicableCanada
Sleep-eze Eze-liquidSolution50 mgOralMedtech Laboratories, Inc.2015-03-30Not applicableCanada
Sleep-eze Regular Strength CapletsTablet25 mgOralMedtech Laboratories, Inc.1997-11-12Not applicableCanada
Sleepaid Extra Strength CapsulesCapsule50 mgOralTanta Pharmaceuticals IncNot applicableNot applicableCanada
SleepinalCapsule50 mg/1OralBlairex Laboratories, Inc.1999-10-01Not applicableUs
SleepTimeCapsule, liquid filled25 mg/1OralShopko Stores Operating2016-07-27Not applicableUs
SleeptimeSolution50 mg/30mLOralShopko Stores Operating2016-07-27Not applicableUs
Sleeptime Dry CoughSolution12.5 mgOralPerrigo InternationalNot applicableNot applicableCanada
SleepwellTablet25 mgOralStella Pharmaceutical Canada Inc.2001-11-202008-06-26Canada
Smart Sense AllergyTablet25 mg/1OralKmart Corporation2011-01-06Not applicableUs
Smart Sense AllergyLiquid12.5 mg/5mLOralKmart Corporation2011-01-13Not applicableUs
Smart Sense AllergyCapsule25 mg/1OralKmart Corporation1996-01-23Not applicableUs
smart sense Allergy ReliefTablet25 mg/1OralKmart Corporation2014-02-20Not applicableUs
Smart Sense Allergy ReliefCapsule25 mg/1OralKmart Corporation2014-02-10Not applicableUs
Smart Sense Childrens allergy reliefSolution12.5 mg/5mLOralKmart Corporation2014-02-21Not applicableUs
Smart Sense Nightime Sleep AidTablet25 mg/1OralKmart Corporation2007-06-29Not applicableUs
Smart Sense Nighttime Sleep AidSolution50 mg/30mLOralKmart Corporation2015-10-21Not applicableUs
Smart Sense Nighttime Sleep AidCapsule, liquid filled25 mg/1OralKmart Corporation2015-10-21Not applicableUs
Smart Sense Sleep AidTablet25 mg/1OralKmart Corporation2014-04-18Not applicableUs
SnoozEase Nighttime Sleep-AidCapsule, liquid filled25 mg/1OralP & L Development Of New York Corporation2013-04-11Not applicableUs
SohMed AllergyTablet25 mg/1OralSOHM Inc.2013-08-25Not applicableUs
SominexTablet25 mg/1OralGlaxo Smith Kline Consumer Heathcare Lp2010-11-08Not applicableUs
SominexTablet25 mg/1OralMedtech Laboratories, Inc.2012-06-01Not applicableUs
SominexTablet25 mg/1OralNavajo Manuracturing Company2016-09-22Not applicableUs
Sominex Extra Strength Caplet 50mgTablet50 mgOralGlaxosmithkline Inc1992-12-312012-06-13Canada
Sominex MaxTablet50 mg/1OralMedtech Laboratories, Inc.2012-06-01Not applicableUs
Sominex Tablets 25mgTablet25 mgOralGlaxosmithkline Inc1992-12-312012-06-13Canada
Somnapure Clinical StrengthTablet, coated50 mg/1OralNutra Click, Llc2015-04-09Not applicableUs
Somnapure Clinical StrengthTablet, coated50 mg/1OralNutra Click, Llc2015-05-26Not applicableUs
SomnitabsTablet25 mg/1OralFred's1990-04-10Not applicableUs
SomnitabsTablet25 mg/1OralGreat Lakes Wholesale, Marketing, and Sales, Inc.1992-12-25Not applicableUs
Sound Body Childrens Allergy ReliefSolution12.5 mg/5mLOralBig Lots Stores, Inc.2016-01-12Not applicableUs
Sound Body Nighttime Sleep AidSolution50 mg/30mLOralBig Lots Stores, Inc.2015-04-21Not applicableUs
Sound Body Sleep AidCapsule25 mg/1OralAllegiant Health2015-03-03Not applicableUs
Sun Mark allergy reliefCapsule25 mg/1OralMc Kesson2003-07-03Not applicableUs
SunMark Allergy ReliefTablet25 mg/1OralMc Kesson2003-08-21Not applicableUs
Sunmark Allergy Relief AntihistamineSolution12.5 mg/5mLOralMc Kesson2003-08-21Not applicableUs
Sunmark Allergy Relief AntihistamineSolution12.5 mg/5mLOralNucare Pharmaceuticals, Inc.2003-08-21Not applicableUs
SunMark Night Time Sleep AidTablet25 mg/1OralMc Kesson2003-08-21Not applicableUs
Sunmark z sleepSolution50 mg/30mLOralMc Kesson2013-07-16Not applicableUs
Sunmark z-sleepCapsule, liquid filled25 mg/1OralMc Kesson2014-01-31Not applicableUs
TexaClear Nighttime Sleep-AidLiquid50 mg/30mLOralGm Pharmaceuticals2016-06-15Not applicableUs
The Itch Eraser Max StrengthGel20 mg/gTopicalTender Corporation2015-11-17Not applicableUs
The Itch Eraser Max StrengthSpray20 mg/mLTopicalTender Corporation2015-12-04Not applicableUs
The Itch Eraser With AntihistamineCream2 %TopicalTender CorporationNot applicableNot applicableCanada
Topcare AllergyTablet25 mg/1OralTopco Associates1993-12-142016-10-29Us
Topcare AllergyCapsule25 mg/1OralTopco Associates1988-01-15Not applicableUs
Topcare childrens allergySolution12.5 mg/5mLOralTopco Associates1987-12-15Not applicableUs
Topcare Clear TimeTablet, film coated25 mg/1OralTopco Associates2015-01-14Not applicableUs
Topcare Sleep AidTablet25 mg/1OralTopco Associates2010-11-03Not applicableUs
Topcare Sleep Aid NighttimeTablet25 mg/1OralTopco Associates2001-09-11Not applicableUs
Topcare ZZZ SleepSolution50 mg/30mLOralTopco Associates2013-08-20Not applicableUs
Topcare ZZZ SleepCapsule, liquid filled25 mg/1OralTopco Associates2014-01-28Not applicableUs
Tranquil NighttimeTablet25 mg/1OralAlva Amco Pharmacal Companies, Inc.2010-08-30Not applicableUs
Triaminic Thin Strips Cough & Runny NoseStrip12.5 mgOralGlaxosmithkline Inc2004-11-19Not applicableCanada
UnisomTablet50 mgOralPaladin Labs Inc1982-12-31Not applicableCanada
Unisom C Nightime Sleep Aid Cap 50mgCapsule50 mgOralPfizer Canada Inc., Consumer Healthcare Division1989-12-311998-08-12Canada
Unisom Sleep GelsCapsule25 mgOralPaladin Labs Inc2012-03-20Not applicableCanada
Unisom Sleep Gels Extra StrengthCapsule50 mgOralPaladin Labs Inc1996-09-05Not applicableCanada
Unisom SleepGels Nighttime Sleep-AidCapsule, liquid filled50 mg/1OralChattem, Inc.2007-01-01Not applicableUs
Unisom SleepMelts Nighttime Sleep-AidTablet, chewable25 mg/1OralChattem, Inc.2008-01-01Not applicableUs
Unisom SleepMinis Nighttime Sleep-AidCapsule25 mg/1OralChattem, Inc.2015-04-01Not applicableUs
Unisom Warming CherryLiquid50 mg/30mLOralChattem, Inc.2013-12-02Not applicableUs
Up and Up Allergy ReliefTablet25 mg/1OralTarget Corporation.2009-06-12Not applicableUs
Up and Up Allergy ReliefCapsule25 mg/1OralTarget Corporation.2009-06-10Not applicableUs
Up and Up Childrens allergy medicationLiquid12.5 mg/5mLOralTarget Corporation.2009-07-08Not applicableUs
Up and Up Dye-free Childrens AllergySyrup12.5 mg/5mLOralTarget Corporation.2015-02-12Not applicableUs
Up and Up Nighttime Sleep-aidLiquid50 mg/30mLOralTarget Corporation.2015-10-20Not applicableUs
Vanamine PDLiquid6.25 mg/mLOralGm Pharmaceuticals2016-04-04Not applicableUs
Vicks QlearQuil Nighttime Allergy ReliefTablet25 mg/1OralProcter And Gamble2014-03-01Not applicableUs
Vicks ZzzQuil Liquid and Liquicaps ComboKitOralProcter And Gamble2013-05-01Not applicableUs
Wal DrylSolution50 mg/20mLOralWalgreen2016-04-25Not applicableUs
Wal Dryl Allergy ChildrensSolution12.5 mg/5mLOralWalgreen1989-07-15Not applicableUs
Wal Dryl Childrens AllergyLiquid12.5 mg/5mLOralWalgreens2015-04-30Not applicableUs
Wal Som Nighttime Sleep AidCapsule25 mg/1OralWalgreen2016-04-04Not applicableUs
Wal-DrylCapsule25 mg/1OralWalgreen1990-03-15Not applicableUs
Wal-Dryl AllergyLiquid25 mg/10mLOralWalgreens2014-08-31Not applicableUs
Wal-dryl AllergyTablet25 mg/1OralWalgreen1990-03-02Not applicableUs
Wal-Dryl Allergy Dye-FreeCapsule, liquid filled25 mg/1OralWalgreen2015-03-01Not applicableUs
Wal-Sleep ZTablet, film coated25 mg/1OralWalgreen2015-07-24Not applicableUs
Wal-Sleep ZCapsule, liquid filled25 mg/1OralWalgreen2015-02-28Not applicableUs
Wal-Sleep Z Diphenhydramine HCl / Sleep AidCapsule, gelatin coated50 mg/21OralWalgreen2011-12-08Not applicableUs
Wal-Sleep Z NighttimeLiquid50 mg/30mLOralWalgreen2016-09-12Not applicableUs
Wal-SomTablet25 mg/1OralWalgreen2012-08-22Not applicableUs
Welby Allergy ReliefTablet25 mg/1OralAldi, Inc2017-07-14Not applicableUs
X3 On-the-GO First Aid Topical Analgesic Itch Relief SpraySpray2.0 %TopicalNatural Essentials, Inc2012-04-24Not applicableCanada
Z-sleepCapsule, liquid filled25 mg/1OralMc Kesson (Health Mart)2015-02-28Not applicableUs
Zzz SleepSolution50 mg/30mLOralWestern Family Foods2013-08-29Not applicableUs
Zzz SleepCapsule, liquid filled25 mg/1OralWestern Family Foods2014-01-28Not applicableUs
Zzz TimeCapsule, liquid filled25 mg/1OralMeijer Distribution2014-02-07Not applicableUs
ZzzquilCapsule25 mgOralProcter And Gamble2013-02-12Not applicableCanada
ZzzQuilCapsule, liquid filled50 mg/21OralLil' Drug Store Products, Inc.2015-12-23Not applicableUs
Zzzquil Alcohol FreeLiquid50 mgOralProcter And GambleNot applicableNot applicableCanada
ZzzQuil Alcohol Free Nighttime Sleep-AidSolution50 mg/30mLOralProcter And Gamble2015-02-03Not applicableUs
Zzzquil LiquidLiquid50 mgOralProcter And Gamble2014-08-15Not applicableCanada
ZZZQuil Nightime Sleep-AidCapsule, gelatin coated25 mg/1OralNavajo Manuracturing Company2016-09-29Not applicableUs
ZzzQuil Nighttime Sleep-AidCapsule, gelatin coated50 mg/21OralProcter And Gamble2011-12-08Not applicableUs
ZzzQuil Nighttime Sleep-AidLiquid50 mg/30mLOralProcter And Gamble2011-12-08Not applicableUs
ZzzQuil Nighttime Sleep-AidSolution50 mg/30mLOralProcter And Gamble2015-02-03Not applicableUs
ZzzSleepCapsule, liquid filled25 mg/1OralVelocity Pharma2013-10-15Not applicableUs
ZZZTimeLiquid50 mg/30mLOralMeijer Distribution2013-07-08Not applicableUs
Unapproved/Other Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
DicopanolKitOralFusion Pharmaceuticals LLC2010-02-08Not applicableUs
DicopanolKitOralCalifornia Pharmaceuticals, Llc2016-01-01Not applicableUs
Diphenhydramine HClCapsule25 mg/1OralCardinal Health2011-06-032017-07-18Us
Diphenhydramine HClTablet25 mg/1OralCardinal Health2011-06-03Not applicableUs
International Brands
NameCompany
AlerylNot Available
AlledrylNot Available
AllerdrylValeant
BaramineNot Available
BeldinNot Available
BelixNot Available
BenylanBiogen
DermodrinMontavit
DesentolMeda
DibondrinMontavit
DimedrolZdorovie
DiphenWockhardt
Dormarex 2Not Available
GenahistNot Available
HistaxinMeda
HyrexinHyrex
Nytol QuickgelsGlaxoSmithKline
RestaminKowa Souyaku
SiladrylNot Available
Silphen CoughNot Available
Brand mixtures
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
7 Select Ibuprofen PMTablet, coatedOral7 Eleven2014-08-05Not applicableUs
7 Select Night Time Severe Cold Cough and FluPowder, for solutionOral7 Eleven2016-01-25Not applicableUs
7 Select Night Time severe cold, cough and fluPowder, for solutionOral7 Eleven2015-11-12Not applicableUs
7 Select Pain Relief PMTablet, film coatedOral7 Eleven2014-09-04Not applicableUs
7-Select Advil PMTablet, coatedOralLil' Drug Store Products, Inc.2011-06-01Not applicableUs
Aceta-gesicTablet, coatedOralRugby2014-06-30Not applicableUs
AcetadrylTablet, film coatedOralPhysicians Science & Nature Inc.2011-07-21Not applicableUs
Acetaminophen / Diphenhydramine 500/25 mgTabletOralReliable 1 Laboratories2015-11-01Not applicableUs
Acetaminophen and Diphenhydramine HClTabletOralRugby2010-10-06Not applicableUs
Acetaminophen and Diphenhydramine HydrochlorideTablet, film coatedOralWalmart Stores2014-06-01Not applicableUs
Acetaminophen Diphenhydramine HClTabletOralChain Drug Consortium2016-02-25Not applicableUs
Acetaminophen Extra StrengthTablet, film coatedOralSave A Lot Food Stores, Ltd.1994-05-15Not applicableUs
Acetaminophen PMTablet, coatedOralRite Aid2001-10-02Not applicableUs
Acetaminophen PM Extra StrengthTablet, coatedOralSafeway2015-05-31Not applicableUs
Acetaminophen PM Rapid ReleaseTablet, coatedOralAAA Pharmaceutical, Inc.2014-03-26Not applicableUs
Acetaminophen PMExtra Strength Extra StrengthTablet, coatedOralMc Kesson (Health Mart)2012-10-192016-12-31Us
Acetaminophen With Antihistamine NighttimeTabletOralLaboratoires Trianon IncNot applicableNot applicableCanada
Acetaminophen, Diphenhydramine HydrochlorideTablet, coatedOralAAA Pharmaceutical, Inc.2012-12-22Not applicableUs
Acetaminophen, Diphenhydramine Hydrochloride, Phenylephrine HydrochlorideTablet, coatedOralAAA Pharmaceutical, Inc.2012-12-22Not applicableUs
Acetaminophen, Diphenhydramine Hyhrochloride, Phenylephrine HydrochlorideTablet, coatedOralAAA Pharmaceutical, Inc.2012-12-22Not applicableUs
Added Strength PMTablet, film coatedOralWestern Family Foods1997-11-25Not applicableUs
Advil Cold & FluTabletOralPfizer Laboratories Div Pfizer Inc.2011-10-27Not applicableCanada
Advil Cold, Cough & Flu NighttimeCapsuleOralPfizer Laboratories Div Pfizer Inc.2013-08-06Not applicableCanada
Advil Day/night Convenience PackCapsule; KitOralPfizer Laboratories Div Pfizer Inc.2014-06-02Not applicableCanada
Advil NighttimeCapsuleOralPfizer Laboratories Div Pfizer Inc.2011-01-03Not applicableCanada
Advil Pain & Head Cold NightTabletOralPfizer Laboratories Div Pfizer Inc.Not applicableNot applicableCanada
Advil PMTablet, coatedOralLil' Drug Store Products, Inc.2010-05-11Not applicableUs
AiracofLiquidOralCenturion Labs2010-01-082016-10-13Us
Alahist LQLiquidOralPoly Pharmaceuticals2007-12-20Not applicableUs
Aleve NighttimeTabletOralBayer Inc Consumer Care2016-02-24Not applicableCanada
Aleve PMTablet, film coatedOralBayer Health Care Llc.2014-09-09Not applicableUs
Alka-Seltzer Plus Night Severe Cold, Cough And FluPowderOralBayer Health Care Llc, Consumer Care2012-07-31Not applicableUs
Allegra Cooling Relief Anti-ItchCreamTopicalChattem, Inc.2012-12-01Not applicableUs
Allegra Intensive Relief Anti-ItchCreamTopicalChattem, Inc.2012-12-01Not applicableUs
Allergic Itch ReliefCreamTopicalValue Merchandisers2011-12-01Not applicableUs
AllergyTabletOralFred's2005-06-06Not applicableUs
Allergy and ColdCapsule, gelatin coatedOralWoonsocket Prescription Center, Incorporated2009-07-10Not applicableUs
Allergy and Cold PETablet, coatedOralSelect Brand2008-10-09Not applicableUs
Allergy and Cold ReliefCapsuleOralTarget Corporation.2009-07-10Not applicableUs
Allergy and Sinus HeadacheTablet, film coatedOralWalmart Stores2005-06-152017-08-19Us
Allergy and Sinus Headache Relief CompleteTabletOralWin Co Foods, Llc,2005-06-15Not applicableUs
Allergy CreamCreamTopicalGw Pharmaceuticals Ltd.2003-07-222011-08-22Canada
Allergy DTabletOralCvs Health2005-08-10Not applicableUs
Allergy Plus Severe Sinus HeadacheTablet, coatedOralAmerisource Bergen2011-06-29Not applicableUs
Allergy Plus Sinus HeadacheTablet, coatedOralTop Care2013-07-01Not applicableUs
Allergy Plus Sinus ReliefTabletOralRite Aid2005-08-10Not applicableUs
Allergy Relief Plus Sinus HeadacheTablet, coatedOralChain Drug Marketing Association2007-11-28Not applicableUs
Allergy SevereTabletOralL&R Distributors, Inc.2005-06-06Not applicableUs
Allergy Sinus Headache CapletsTabletOralTanta Pharmaceuticals Inc2002-01-04Not applicableCanada
Allergy Sinus Nighttime ReliefTabletOralVita Health Products Inc2012-01-12Not applicableCanada
Allergy, Sinus and Headache Relief MedicationTabletOralPharmetics (2011) Inc.Not applicableNot applicableCanada
Anti ItchCreamTopicalMeijer Distribution2010-03-17Not applicableUs
Anti Itch and Skin ProtectantCreamTopicalRite Aid2005-07-30Not applicableUs
Anti Itch CreamCreamTopicalNeopharm Co., Ltd2010-09-07Not applicableUs
Anti Itch SpraySprayTopicalH.J. Sutton Industries Ltd.Not applicableNot applicableCanada
Anti itch Topical AnalgesicCreamTopicalChain Drug Marketing Association2014-02-20Not applicableUs
Anti-ItchCreamTopicalAmerisource Bergen2005-09-20Not applicableUs
Anti-Itch CreamCreamTopicalTrifecta Pharmaceuticals Usa, Llc.2016-12-29Not applicableUs
Anti-Itch Extra StrengthCreamTopicalPersonal Care Products2013-07-10Not applicableUs
Anti-Itch Maximum StrengthCreamTopicalFred's2008-08-08Not applicableUs
Anti-itch Plus CreamCreamTopicalTaro Pharmaceuticals, Inc.Not applicableNot applicableCanada
Anti-Itch Wal-DrylSprayTopicalWalgreens2011-07-08Not applicableUs
Antiphlamine Coin PlasterPatchTopicalHanul Trading Co., Ltd.2016-10-102017-02-11Us
Army and Airforce Exchange Ibuprofen PMTablet, coatedOralArmy + Air Force Exchange Service2015-08-28Not applicableUs
Assured Headache PM (Aspirin Free)Tablet, coatedOralSpirit Pharmaceuticals, Llc2016-08-12Not applicableUs
Assured Night time Cold and CoughLiquidOralBio Pharm, Inc.2011-11-01Not applicableUs
Atopalm Itch ReliefCreamTopicalNeopharm Co., Ltd2011-03-16Not applicableUs
AuroFlu Flu and Sore Throat Warming ReliefSyrupOralAurohealth LLC2015-02-21Not applicableUs
AuroFlu Night Time Severe Cold and CoughSyrupOralAurohealth LLC2016-06-09Not applicableUs
AuroFlu Night Time Severe Cold and Cough Warming ReliefSyrupOralAurohealth LLC2015-02-21Not applicableUs
Aurophen Daytime NighttimeKitAurohealth LLC2015-11-04Not applicableUs
Aurophen Pain Away plus Sleep aidLiquidOralAurohealth LLC2015-03-27Not applicableUs
Aurophen PM Extra StrengthTabletOralAurohealth LLC2016-02-24Not applicableUs
Balminil Codeine Night Time + ExpectorantLiquidOralRougier Pharma Division Of Ratiopharm Inc2003-06-032015-10-01Canada
Balminil Night-timeSyrupOralTeva2001-03-20Not applicableCanada
BanophenCreamTopicalMajor2009-06-19Not applicableUs
Bayer PMTablet, coatedOralBayer Health Care Llc, Consumer Care2015-01-12Not applicableUs
Benadryl Allergy & Cold CapletsTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Benadryl Allergy & SinusSyrupOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Benadryl Allergy Plus CongestionTablet, film coatedOralJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2017-06-19Not applicableUs
Benadryl Allergy Rapid ReleaseTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Benadryl Allergy Sinus CapletsTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc1997-03-032016-01-22Canada
Benadryl Allergy Sinus HeadacheTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Benadryl Bug Bite ReliefLiquidTopicalMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2007-03-09Not applicableCanada
Benadryl Decongestant TabletsTabletOralWarner Lambert Canada Inc.1987-12-311997-08-26Canada
BENADRYL Extra Strength Itch CoolingSprayTopicalJohnson & Johnson2012-03-22Not applicableUs
Benadryl Extra Strength Itch ReliefSolutionTopicalJohnson & Johnson2012-04-01Not applicableUs
Benadryl Extra Strength Itch StoppingCreamTopicalJohnson & Johnson2012-10-15Not applicableUs
Benadryl Original Strength Itch StoppingCreamTopicalJohnson & Johnson2012-10-15Not applicableUs
Benadryl PE Total Extra StrengthTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Benadryl PE Total Regular StrengthTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Benadryl ReadyMist Itch StoppingSprayTopicalJohnson & Johnson2014-10-062016-12-01Us
Benadryl SpraySprayTopicalMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2007-03-09Not applicableCanada
Benadryl TotalTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2004-10-15Not applicableCanada
Benylin All-IN-one Cold and Flu Night Extra StrengthTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2005-09-23Not applicableCanada
Benylin All-IN-one Cold and Flu Night PE CapletsTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2006-09-132016-01-22Canada
Benylin Cold and Sinus Night CapletsTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Benylin for Children All-IN-one Cold & Fever NightimeSuspensionOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2008-09-01Not applicableCanada
Berkley and Jensen Ibuprofen PMTablet, coatedOralBJWC2009-04-27Not applicableUs
Best Choice Nighttime Severe Cold and Cough Honey Lemon infused with Chamomile and White Tea FlavorsGranule, for solutionOralQuality Home Products2013-11-19Not applicableUs
Bi Electro Extra StrengthTabletOralGenomma Lab2015-04-27Not applicableUs
Bite and ItchLotionTopicalWeeks & Leo Co., Inc.2000-01-062016-10-13Us
Buckley's Complete Cough, Cold & Flu NightTabletOralThe Buckley's CompanyNot applicableNot applicableCanada
Buckley's Complete PM - NighttimeLiquidOralThe Buckley's Company2012-10-04Not applicableCanada
Buckley's Night Time MixtureSyrupOralThe Buckley's Company1997-06-23Not applicableCanada
Bye Bye Bite LotLotionTopicalDavid D. Daniels Ltd.1990-12-311998-01-16Canada
CalmylinLiquidOralTeva1981-12-31Not applicableCanada
Calmylin #4 SyrSyrupOralTechnilab Pharma Inc.1992-12-312003-09-24Canada
Care One Flu and Severe Cold and Cough NighttimePowder, for solutionOralAmerican Sales Company2010-11-07Not applicableUs
Care One Ibuprofen PMTablet, coatedOralAmerican Sales Company2009-02-20Not applicableUs
Care One Pain Relief and Pain Relief PMKitAmerican Sales Company2006-09-30Not applicableUs
Care One Pain Relief PM Extra StrengthTablet, film coatedOralAmerican Sales Company2004-04-13Not applicableUs
CAREALL Non-Aspirin PM Extra StrengthTabletOralNew World Imports2016-03-01Not applicableUs
CareOne Acetaminophen PMTablet, coatedOralAmerican Sales Company2016-09-02Not applicableUs
Careone AllergyCreamTopicalAmerican Sales Company2012-03-01Not applicableUs
CareOne Day Time Severe Cold Night Time Cold and FluKitAmerican Sales Company2014-08-26Not applicableUs
Careone Ibuprofen PMTablet, coatedOralAmerican Sales Company2011-12-08Not applicableUs
Careone night time severe cold and cough honey lemon infused with chamomile and white tea flavorsGranule, for solutionOralQuality Home Products2013-10-24Not applicableUs
CareOne Pain Relief Pain Relief PMKitAmerican Sales Company2013-11-02Not applicableUs
Careone Pain Relief PMTablet, film coatedOralAmerican Sales Company2012-02-03Not applicableUs
CareOne Triacting Night Time Cold and Cough ChildrensSolutionOralAmerican Sales Company2009-06-05Not applicableUs
Children's Allergy and Sinus Medication Liquid SuspensionSuspensionOralPharmetics (2011) Inc.Not applicableNot applicableCanada
Children's Benadryl-D Allergy & SinusLiquidOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Children's Benadryl-D SyrupSyrupOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2014-03-03Not applicableCanada
Children's Tylenol Allergy - D Chewable TabletsTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2000-03-152002-07-19Canada
Children's Tylenol Allergy-D SuspensionSuspensionOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2000-06-152005-07-22Canada
Children's Tylenol Cold and Cough NighttimeSuspensionOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2006-08-31Not applicableCanada
Children's Tylenol Complete Cold, Cough & Fever NighttimeSuspensionOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2014-06-15Not applicableCanada
Childrens Allergy Plus CongestionLiquidOralHyvee2015-04-30Not applicableUs
Childrens Benadryl Allergy Plus CongestionSolutionOralJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2014-09-30Not applicableUs
Childrens Benadryl-D ALLERGY and SINUSSolutionOralJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2008-08-012016-10-13Us
Childrens Cold and Cough NighttimeLiquidOralWalgreens2014-08-31Not applicableUs
Childrens Cough and Cold NighttimeSolutionOralCvs Health2015-07-22Not applicableUs
Childrens Delsym Cough Plus Cold Night TimeSolutionOralReckitt Benckiser2013-03-18Not applicableUs
Childrens Dimetapp Multi-Symptom Cold and FluLiquidOralRichmond Division of Wyeth2014-07-01Not applicableUs
Childrens Dimetapp Nighttime Cold and CongestionLiquidOralRichmond Division Of Wyeth Llc, A Subsidiary Of Pfizer Inc.2007-11-01Not applicableUs
Childrens Mucinex Multi Symptom Cold and Childrens Mucinex Night Time Multi Symptom ColdKitReckitt Benckiser2014-04-01Not applicableUs
Childrens Mucinex Night Time Multi-Symptom ColdSolutionOralReckitt Benckiser2013-03-25Not applicableUs
Childrens Night Time Cold and CoughLiquidOralValu Merchandisers Company (Best Choice)2014-07-31Not applicableUs
Childrens Night Time COUGH and COLD RELIEFLiquidOralChain Drug Consortium2012-09-01Not applicableUs
Childrens Nighttime Cold and CoughLiquidOralFamily Dollar (FAMILY WELLNESS)2014-07-31Not applicableUs
Childrens TriactingSolutionOralWestern Family Foods2007-08-30Not applicableUs
Childrens Triacting Night Time Cold and CoughLiquidOralAmerisource Bergen (Good Neighbor Pharmacy) 461222015-09-30Not applicableUs
Childrens Triacting Nighttime Cold and CoughLiquidOralQuality Choice (Chain Drug Marketing Association, Inc.)2014-11-30Not applicableUs
Childrens Triacting Nighttime Cold and Cough ReadyInCaseLiquidOralP & L Development, LLC2014-11-30Not applicableUs
Cold & Flu-IN-oneKit; TabletOralVita Health Products Inc2012-04-25Not applicableCanada
Cold and Congestion Childrens NighttimeLiquidOralWalgreens2016-03-31Not applicableUs
Cold and CoughSolutionOralMeijer Distribution2007-10-31Not applicableUs
Cold and Cough MULTI-SYMPTOM DAYTIME / NIGHTTIMEKitWalgreen2005-07-21Not applicableUs
Cold and FluTablet, film coatedOralHyvee2015-01-11Not applicableUs
Cold and Flu NighttimeTablet, film coatedOralWestern Family Foods2014-09-26Not applicableUs
Cold and Flu ReliefPowderOralPharmetics (2011) Inc.2015-10-02Not applicableCanada
Cold-EEZE Childrens Nighttime Cold and Cough ReliefLiquidOralPro Phase Labs, Inc.2016-01-01Not applicableUs
Cold-EEZE Nighttime Cold and FluLiquidOralPro Phase Labs, Inc.2016-01-01Not applicableUs
Complete One Cold and Flu Nightime Extra Strength TabletsTabletOralTanta Pharmaceuticals IncNot applicableNot applicableCanada
Complete One Cold and Flu PE NightTabletOralPharmetics (2011) Inc.Not applicableNot applicableCanada
ConRx PMTabletOralEagle Distributors,Inc.2013-02-15Not applicableUs
Contac ColdTabletOralGlaxosmithkline IncNot applicableNot applicableCanada
Contac Cold and Fever CapletsTabletOralGlaxosmithkline Inc2000-12-012008-08-01Canada
Contac Day & Night Sinus/allergy CapletTabletOralSmithkline Beecham Consumer Healthcare, Division Of Smithkline Beecham Inc.1994-12-311996-09-13Canada
Contac Night CapletsTabletOralGlaxosmithkline Inc1999-05-132008-08-01Canada
Contac-C Ext.stren.night Time Cough,cold&fluTabletOralSmithkline Beecham Consumer Healthcare, Division Of Smithkline Beecham Inc.1996-12-311997-08-15Canada
Contrast Allergy PreMed PackKitShertech Laboratories, Llc2016-09-13Not applicableUs
Coricidin II Night Time Cold and FluTabletOralSchering Plough Healthcare Products Canada, A Division Of Schering Canada Inc.Not applicableNot applicableCanada
Cough Syr W Codeine Diphenhyd HCl & Ammon ClSyrupOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1989-12-311997-08-08Canada
Cough SyrupSyrupOralTeva1986-12-31Not applicableCanada
Cough, Cold & FluKit; TabletOralVita Health Products Inc2012-09-13Not applicableCanada
Cough, Cold and Flu Nightime CapletsTabletOralVita Health Products Inc2003-11-21Not applicableCanada
Cough, Cold and Flu Relief Complete Night Super StrengthTabletOralPharmetics (2011) Inc.Not applicableNot applicableCanada
CounterAct NightTablet, coatedOralMelaleuca, Inc.2011-08-01Not applicableUs
CounterAct PMTabletOralMelaleuca, Inc.2011-04-01Not applicableUs
CVS cough and severe cold night time honey lemon infused with chamomile and white tea flavorsGranule, for solutionOralQuality Home Products2009-10-31Not applicableUs
Cvs Effervescent Pain Relief PMTabletOralCvs Health2015-02-02Not applicableUs
CVS Extra Strength Itch ReliefOintmentTopicalCvs Health2010-09-13Not applicableUs
CVS Health Medication and Topical Refill PouchKitTopicalCvs Health2016-12-28Not applicableUs
CVS Health Nighttime Severe Cough and Cold Nighttime Severe Cold and CoughPowder, for solutionOralCvs Health2015-08-17Not applicableUs
CVS Pharmacy Nighttime Severe Cough and Cold honey lemon infused with chamomile and white tea flavorsGranule, for solutionOralCvs Health2013-03-25Not applicableUs
Damylin Avec Codeine SiropSyrupOralLaboratoire Atlas IncNot applicableNot applicableCanada
Damylin With Codeine SyrupSyrupOralLaboratoire Riva Inc2002-09-13Not applicableCanada
Day and Night ColdKitAAA Pharmaceutical, Inc.2012-12-28Not applicableUs
Day and Night Cold PEKitMeijer2011-08-012015-12-31Us
Day and Night Sinus Maximum StrengthKitWalmart Stores2014-06-30Not applicableUs
Daytime and Nighttime Pain ReliefKitCvs Health2015-11-13Not applicableUs
Daytime Cold and Cough and NightTime Cold and Congestion ChildrensKitTarget Corporation.2015-07-31Not applicableUs
Daytime Mucus Relief Nighttime Cold and FluKitHyvee2015-09-08Not applicableUs
Daytime Nighttime Cold and Cough ChildrensKitWalgreens2014-09-30Not applicableUs
Daytime Nighttime Severe Cough and ColdKitCvs Health2015-09-15Not applicableUs
DAYTIME SEVERE COLD and COUGH NIGHTTIME SEVERE COLD and COUGHKitCvs Health2015-12-09Not applicableUs
Daytime Sinus Nighttime Sinus Maximum StrengthKitTarget Corporation.2013-06-30Not applicableUs
Delsym Childrens Night Time Cough and ColdLiquidOralReckitt Benckiser2011-08-102017-01-24Us
Delsym Cough Plus Cold Night TimePowder, for solutionOralReckitt Benckiser2014-04-01Not applicableUs
Delsym Night Time Cough and ColdLiquidOralReckitt Benckiser2011-07-012017-01-24Us
Dermamine Extra Strength Itch StoppingCreamTopicalNatureplex, LLC2014-03-01Not applicableUs
Dermarest Plus - GelGelTopicalDel Pharmaceuticals Inc.1998-01-012008-12-16Canada
Dg Health Anti ItchCreamTopicalDolgencorp2010-03-16Not applicableUs
Dg Health Flu and Severe Cold and CoughPowder, for solutionOralDolgencorp2014-03-15Not applicableUs
Dg Health Headache Relief PMTablet, film coatedOralDolgencorp2010-02-14Not applicableUs
dg health Ibuprofen pmTablet, coatedOralDolgencorp2010-01-24Not applicableUs
Dg Health Pain Relief PMTablet, film coatedOralDolgencorp2011-01-27Not applicableUs
Dg Health Pain Relief PM Extra StrengthTablet, film coatedOralDolgencorp2009-11-21Not applicableUs
Dg Health Triacting Night Time Cold and CoughSolutionOralDolgencorp2009-11-14Not applicableUs
DG Health TussinSolutionOralDolgencorp2016-08-01Not applicableUs
Diabetic Tussin Nighttime Cold and FluLiquidOralHealth Care Products2010-08-01Not applicableUs
DiphenhydramineCreamTopicalPhysicians Total Care, Inc.2008-04-23Not applicableUs
Diphenhydramine DCreamTopicalNexmed Usa Inc2011-08-29Not applicableUs
Diphenhydramine HCl and Zinc AcetateCreamTopicalPerrigo New York Inc.2005-12-05Not applicableUs
Diphenhydramine Hydrochloride and Zinc AcetateCreamTopicalTaro Pharmaceuticals U.S.A., Inc.2005-09-20Not applicableUs
DM Cough SyrupSyrupOralProdemdis Enr.1992-12-312010-07-15Canada
DM Plus Cough SyrupSyrupOralTechnilab Pharma Inc.1995-12-312005-08-05Canada
DM SyrupSyrupOralTechnilab Pharma Inc.1986-12-311997-08-22Canada
Doctor Manzanilla Allergy and Decongestant ReliefSyrupOralMid Valley Pharmaceuticals Llc2017-01-12Not applicableUs
Doctor Manzanilla Cough and ColdSyrupOralMid Valley Pharmaceuticals Llc2017-01-09Not applicableUs
Doctor Manzanilla Cough Suppressant and Nasal DecongestantSolutionOralMid Valley Pharmaceuticals Llc2014-03-04Not applicableUs
Dr. Cocoa for Children Nighttime Cough + ColdSyrupOralInfirst HealthcareNot applicableNot applicableCanada
Dr. Cocoa Nighttime Cough and ColdLiquidOralInfirst Healthcare2014-06-20Not applicableUs
Dr. Sheffield Anti Itch CreamCreamTopicalFaria Llc Dba Sheffield Pharmaceutcials2008-11-11Not applicableUs
Easy Care First Aid Kit - ComprehensiveKitOral; TopicalTender Corporation2012-01-01Not applicableUs
Equaline Anti ItchCreamTopicalSupervalu2014-03-28Not applicableUs
Equaline Anti-itchCreamTopicalSupervalu2005-09-20Not applicableUs
Equaline Flu and Severe Cold and CoughPowder, for solutionOralSupervalu2014-03-21Not applicableUs
Equaline Ibuprofen PMTablet, coatedOralSupervalu2009-03-02Not applicableUs
Equaline Night Time Cold and Cough ChildrensLiquidOralSupervalu2011-07-14Not applicableUs
Equaline Pain Relief PMTablet, coatedOralSupervalu2004-10-22Not applicableUs
Equaline Pain Relief PM Extra StrengthTablet, film coatedOralSupervalu2004-08-30Not applicableUs
Equate Anti ItchCreamTopicalWalmart Stores2005-06-29Not applicableUs
Equate Flu and Severe Cold and CoughPowder, for solutionOralWalmart Stores2014-02-05Not applicableUs
Equate Ibuprofen PMTablet, coatedOralWalmart Stores2009-04-15Not applicableUs
Equate Night Time Cold and Cough ChildrensLiquidOralWalmart Stores2007-07-19Not applicableUs
Ergodryl CapCapsuleOralErfa Canada 2012 Inc1964-12-312013-07-09Canada
Excedrin PMTabletOralNovartis2010-03-012017-04-14Us
Excedrin PM Triple Action CapletsTablet, coatedOralGlaxo Smith Kline Consumer Healthcare Holdings (Us) Llc2014-09-24Not applicableUs
Extra Strength Acetaminophen PMCapsule, liquid filledOralMc Kesson2012-04-09Not applicableUs
Extra Strength Allergy TotalTabletOralVita Health Products Inc2008-03-11Not applicableCanada
Extra Strength Flu Relief NightimeTabletOralVita Health Products Inc2004-01-07Not applicableCanada
Extra Strength Mapap PMTablet, film coatedOralMajor2011-05-04Not applicableUs
Extra Strength Multi-symptom Relief Sugar FreePowderOralPharmetics (2011) Inc.Not applicableNot applicableCanada
Extra Strength Neocitran Flu SyrupSyrupOralNovartis2006-08-092016-08-02Canada
Extra Strength Neocitran Total Symptom Relief - Sugar FreePowderOralNovartis2009-08-032016-08-02Canada
Extra Strength Night Time Pain MedicineTabletOralGericare Pharmaceuticals1996-01-01Not applicableUs
Extra Strength Nighttime Pain Reliever / Sleep AidTabletOralTevaNot applicableNot applicableCanada
Extra Strength Non-Aspirin PMTablet, film coatedOralSave A Lot Food Stores, Ltd.1994-05-152016-02-18Us
Extra Strength Pain Relief PMTablet, coatedOralDiscount Drug Mart2013-06-20Not applicableUs
Extra Strength Pain Reliever PMTablet, film coatedOralSupervalu1994-05-15Not applicableUs
Extra Strength PM Pain ReliefTablet, film coatedOralDolgencorp1994-05-152017-08-08Us
Extra Strength Sinus Relief NighttimeTabletOralVita Health Products Inc2003-04-252013-06-25Canada
Extra Strength Total Symptom Relief Sugar-freePowderOralPharmetics (2011) Inc.2014-12-04Not applicableCanada
Extra Strength Tylenol Allergy and CoughTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Extra Strength Tylenol Allergy Sinus Nighttime CapletTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2000-05-122016-01-22Canada
Extra Strength Tylenol Complete Cold, Cough & Flu NighttimeTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2011-08-08Not applicableCanada
Extra Strength Tylenol Flu Nighttime GelcapTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc1995-12-312016-01-22Canada
Extra Strength Tylenol NighttimeTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2012-10-02Not applicableCanada
Extra Strength Tylenol Pain and Head Cold NightTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Extra Strength Tylenol Pain and Head Cold Night Rapid ReleaseTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Extra Strength Wal-dryl Itch ReliefSprayTopicalWalgreen2011-01-03Not applicableUs
Facol Cold and Flu Day and NightCapsule, liquid filledOralJw Holdings2015-08-01Not applicableUs
Facol Cold and Flu NightCapsule, liquid filledOralJw Holdings2015-08-01Not applicableUs
Family Care Anti-ItchCreamTopicalUnited Exchange Corporation2014-11-24Not applicableUs
Family Dollar Nighttime Severe Cold and Cough honey lemon infused with chamomile and white tea flavorsGranule, for solutionOralQuality Home Products2015-11-24Not applicableUs
Family WellnessCreamTopicalZhejiang Jingwei Pharmaceutical Co., Ltd.2013-11-01Not applicableUs
Fast Maximum Night Time Cold and FluSolutionOralAmerisource Bergen2016-05-23Not applicableUs
FIRST Dukes Mouthwash CompoundingKitOralCutis Pharma, Inc.2010-12-15Not applicableUs
FIRST Marys Mouthwash CompoundingKitOralCutis Pharma, Inc.2010-12-15Not applicableUs
Flu and Severe Cold and CoughPowder, for solutionOralSafeway2014-08-21Not applicableUs
Flu and Severe Cold and Cough Night TimePowder, for solutionOralMeijer Distribution2010-09-03Not applicableUs
Flu and Severe Cold and Cough NighttimePowder, for solutionOralSafeway2010-11-11Not applicableUs
Flu and Severe Cold and Cough Nite TimePowder, for solutionOralKroger2010-09-02Not applicableUs
Flu and Severe Cold Nighttime ReliefLiquidOralCvs Health2015-05-31Not applicableUs
Flu and Sore ThroatLiquidOralSelect Brand Dist.2010-09-08Not applicableUs
Flu and Sore Throat ReliefLiquidOralChain Drug Consortium2014-07-18Not applicableUs
Flu ReliefKit; TabletOralVita Health Products Inc2012-08-28Not applicableCanada
Flu Relief TherapyLiquidOralWalgreens2009-08-06Not applicableUs
Flu Relief Therapy Night TimeLiquidOralGood Neighbor Pharmacy2009-08-312017-07-01Us
Flu Relief Therapy NighttimeLiquidOralTopcare (Topco Associates Llc)2015-08-31Not applicableUs
Flu Relief Therapy Nighttime Severe ColdLiquidOralSelect Brand Dist.2011-12-28Not applicableUs
Flu Relief Therapy Severe Cough and Cold NighttimeLiquidOralFred's2015-11-30Not applicableUs
Flu, Cough & Cold Complete Day and NightKit; TabletOralVita Health Products Inc2012-07-03Not applicableCanada
Flu, Cough and Sore ThroatLiquidOralCvs Health2016-09-30Not applicableUs
Formu Care Flu and Severe Cold and Cough Night TimePowder, for solutionOralAccess Business Group2010-09-14Not applicableUs
Fulton Street Market Nighttime Flu and Severe Cold and CoughPowder, for solutionOralAccess Business Group2010-09-14Not applicableUs
Good Neighbor Pharmacy Cold and Flu Night TimeTablet, film coatedOralAmerisource Bergen2014-11-09Not applicableUs
Good Neighbor Pharmacy Flu and Severe Cold and CoughPowder, for solutionOralAmerisource Bergen2014-07-31Not applicableUs
Good Neighbor Pharmacy Flu and Severe Cold and Cough NighttimePowder, for solutionOralAmerisource Bergen2011-02-10Not applicableUs
Good Neighbor Pharmacy Headache PMTablet, film coatedOralAmerisource Bergen2000-02-01Not applicableUs
Good Neighbor Pharmacy Ibuprofen PMTablet, coatedOralAmerisource Bergen2009-02-23Not applicableUs
Good Neighbor Pharmacy Itch Relief Extra StrengthAerosol, sprayTopicalAmerisource Bergen Drug Corportaion2011-10-28Not applicableUs
Good Neighbor Pharmacy Mucus Relief Severe Cold Cold and Flu Night TimeKitAmerisource Bergen2015-02-18Not applicableUs
Good Neighbor Pharmacy Pain Relief and Pain Relief PMKitAmerisource Bergen2007-09-05Not applicableUs
Good Neighbor Pharmacy Pain Relief PMTablet, film coatedOralAmerisource Bergen1993-12-27Not applicableUs
Good Neighbor Pharmacy Sinus Relief Day Time Night TimeKitAmerisource Bergen2015-10-23Not applicableUs
Good Sense Flu and Severe Cold and CoughPowder, for solutionOralL. Perrigo Company2014-10-30Not applicableUs
Good Sense Flu and Severe Cold and Cough NighttimePowder, for solutionOralL. Perrigo Company2010-09-17Not applicableUs
Good Sense headache pmTablet, film coatedOralL. Perrigo Company1996-09-12Not applicableUs
Good Sense Ibuprofen PMTablet, coatedOralL. Perrigo Company2009-03-05Not applicableUs
Good Sense Itch ReliefCreamTopicalL. Perrigo Company2006-07-18Not applicableUs
Good Sense Pain Relief PMTablet, film coatedOralL. Perrigo Company2012-01-25Not applicableUs
Good Sense Pain Relief PM Extra StrengthTablet, film coatedOralL. Perrigo Company1992-07-23Not applicableUs
Goodys PM Pain RelieverPowderOralMedtech Laboratories, Inc.2013-09-01Not applicableUs
Harris Teeter Acetaminophen PMTablet, coatedOralHarris Teeter2016-06-13Not applicableUs
Harris Teeter Anti-ItchCreamTopicalHarris Teeter2017-04-21Not applicableUs
Harris Teeter Ibuprofen PMTablet, coatedOralHarris Teeter2015-11-05Not applicableUs
Harris Teeter Sinus ReliefKitHarris Teeter2016-07-31Not applicableUs
Headache Formula PMTablet, film coatedOralSupervalu2004-06-07Not applicableUs
Headache PMTablet, film coatedOralHyvee2015-02-20Not applicableUs
Headache PM Aspirin FreeTablet, film coatedOralGreenbrier International, Inc.2004-06-07Not applicableUs
Headache PM FormulaTablet, film coatedOralHyvee1998-08-30Not applicableUs
Headache Relief PMTabletOralDolgencorp2004-06-072016-02-18Us
Health Mart ibuprofen PMTablet, coatedOralMc Kesson2017-05-30Not applicableUs
Health Mart severe cold cough and fluPowder, for solutionOralMc Kesson2015-10-09Not applicableUs
Healthy Accents Anti ItchCreamTopicalDza Brands,2010-07-21Not applicableUs
Healthy Accents Ibuprofen PMTablet, coatedOralDza Brands,2009-04-15Not applicableUs
Healthy Accents Pain Relief PMTablet, film coatedOralDza Brands,2012-03-08Not applicableUs
Healthy Accents Pain Relief PM Extra StrengthTablet, film coatedOralDza Brands,2008-01-29Not applicableUs
Healthy Accents Severe ColdPowder, for solutionOralDza Brands,2015-09-17Not applicableUs
Healthy Accents Sinus ReliefKitDza Brands,2015-02-06Not applicableUs
Healthy Mama Eazzze The PainTablet, film coatedOralMATERNAL SCIENCE, LLC2013-04-29Not applicableUs
Ibuprofen and Diphenhydramine CitrateTabletOralDr Reddy's Laboratories2010-01-31Not applicableUs
Ibuprofen and Diphenhydramine HClCapsule, liquid filledOralP & L Development Of New York Corporation2011-09-01Not applicableUs
Ibuprofen Daytime, Ibuprofen NighttimeCapsule; KitOralVita Health Products IncNot applicableNot applicableCanada
Ibuprofen NighttimeCapsuleOralVita Health Products Inc2015-01-27Not applicableCanada
Ibuprofen PMTablet, coatedOralWalgreen2009-02-19Not applicableUs
Instant Itch Relief CVSSprayTopicalCvs Health2014-11-13Not applicableUs
Itch Rel Spr CvsSprayTopicalCvs Health2014-02-14Not applicableUs
Itch ReliefCreamTopicalH.E.B.2010-09-15Not applicableUs
Itch Relief CreamCreamTopicalPharmacy Vlaue Alliance Llc2016-07-19Not applicableUs
Itch Relief extra strengthCreamTopicalSafeway2008-11-20Not applicableUs
Itch Relief SprayAerosolTopicalTender CorporationNot applicableNot applicableCanada
Itch Relief StickSolutionTopicalTender CorporationNot applicableNot applicableCanada
Itch StoppingCreamTopicalHyvee2015-09-27Not applicableUs
IvarestCreamTopicalBlistex Corporation2007-12-31Not applicableUs
Jack & Jill Bedtime Cough & ColdSyrupOralThe Buckley's Company2014-08-05Not applicableCanada
Kinkan CoolLinimentTopicalKinkando Co., Ltd.2000-04-26Not applicableUs
KMart - Pain Relief PMSolutionOralKmart Corporation2015-08-17Not applicableUs
Kroger NiteTime Cold and FluLiquidOralKroger2016-04-07Not applicableUs
Kroger NiteTime Flu plus Severe Cold and CoughPowder, for solutionOralKroger2013-06-28Not applicableUs
Leader Anti Itch Maximum StrengthCreamTopicalCardinal Health2012-02-10Not applicableUs
Leader Cold and FluTablet, film coatedOralCardinal Health2015-10-19Not applicableUs
Leader Flu and Severe Cold and CoughPowder, for solutionOralCardinal Health2012-06-13Not applicableUs
Leader Headache PM FormulaTablet, film coatedOralCardinal Health2012-06-25Not applicableUs
Leader Headache Relief PMTablet, film coatedOralCardinal Health2017-05-09Not applicableUs
Leader ibuprofen pmTablet, coatedOralCardinal Health2009-04-27Not applicableUs
Leader Night Time Cough and Cold Childrens TriactingLiquidOralCardinal Health2008-07-24Not applicableUs
Leader Pain Reliever PMTablet, film coatedOralCardinal Health1992-07-07Not applicableUs
Legatrin PMTabletOralLil' Drug Store Products, Inc.2009-11-022017-02-02Us
Live Better Anti-ItchCreamTopicalThe Great Atlantic + Pacific Tea Company2005-09-20Not applicableUs
Lucky Itch StoppingCreamTopicalDelta Brands, Inc2014-11-15Not applicableUs
Meijer Anti-itchCreamTopicalMeijer Distribution2005-09-20Not applicableUs
Meijer Nighttime Severe Cold and Cough Honey Lemon infused with Chamomile and White Tea FlavorsGranule, for solutionOralQuality Home Products2013-09-27Not applicableUs
Midol PMTablet, coatedOralBayer2014-12-15Not applicableUs
Motrin PMTablet, coatedOralJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2010-01-11Not applicableUs
Mountain Series Weekender MedicalKitTender Corporation Dba Adventure Medical Kits2011-08-01Not applicableUs
Mucinex Fast-Max Day Time Severe Cold and Mucinex Fast-Max Night Time Cold and Flu Maximum StrengthKitReckitt Benckiser2014-04-102016-01-15Us
Mucinex Fast-Max Day Time Severe Congestion and Cough - Mucinex Fast-Max Night Time Cold and Flu Maximum StrengthKitReckitt Benckiser2015-08-25Not applicableUs
Mucinex Fast-Max Day Time Severe Congestion and Cough and Mucinex Fast-Max Night Time Cold and Flu Maximum StrengthKitReckitt Benckiser2014-05-09Not applicableUs
Mucinex Fast-Max Night Time Cold and FluPowder, for solutionOralReckitt Benckiser2014-04-012016-11-05Us
Mucinex Fast-Max Night Time Cold and Flu Clear and CoolSolutionOralReckitt Benckiser2016-07-01Not applicableUs
Mucinex Fast-Max Severe Congestion and Cough Clear and Cool and Mucinex Fast-Max Night Time Cold and Flu Clear and CoolKitReckitt Benckiser2016-07-01Not applicableUs
Mucinex Sinus-Max Day Night Maximum StrengthKitReckitt Benckiser2012-09-10Not applicableUs
Mucinex Sinus-Max Day Time Severe Congestion Relief and Mucinex Sinus-Max Night Time Congestion and Cough Maximum StrengthKitReckitt Benckiser2014-04-28Not applicableUs
Mucinex Sinus-Max Night Time Congestion and CoughSolutionOralReckitt Benckiser2014-03-26Not applicableUs
Mucus Relief Day Time and Night TimeKitH.E.B.2015-04-01Not applicableUs
Mucus Relief Daytime/NighttimeKitWalgreen2013-04-07Not applicableUs
Mucus Relief Daytime/Nighttime/Maximum StrengthKitWalgreen2015-07-20Not applicableUs
Mucus Relief Sinus Congestion Daytime Nighttime Maximum StrengthKitWalgreen2013-04-07Not applicableUs
Mucus Relief Sinus Day and NightKitH.E.B.2015-04-01Not applicableUs
Multi Symptom Severe ColdPowder, for solutionOralCvs Health2016-09-14Not applicableUs
Multi Symptom Severe Cold and Nighttime Severe Cold and CoughKitCvs Health2015-09-21Not applicableUs
Multi-Symptom Cold and Cough Daytime NighttimeKitRite Aid2005-07-212019-04-15Us
Multi-Symptom Wal-Phed PETablet, film coatedOralWalgreen2005-06-21Not applicableUs
Neocitran Extra Strength Total Cold NightPowderOralGlaxosmithkline Inc2015-08-04Not applicableCanada
Neocitran Thin Strips Nighttime Cough and ColdStripOralNovartis2007-08-072013-07-31Canada
Neocitran Total Cold NightPowderOralGlaxosmithkline IncNot applicableNot applicableCanada
Night Time Cold & Flu LiquidLiquidOralReckitt BenckiserNot applicableNot applicableCanada
Night Time Cold and Cough ChildrensLiquidOralValu Merchandisers Company (Best Choice)2014-10-31Not applicableUs
Night Time Cough and Cold ReliefLiquidOralChain Drug Consortium2013-01-01Not applicableUs
Night Time Severe Cold and CoughSyrupOralFamily Dollar2016-06-09Not applicableUs
Night Time Severe Cold and Cough ReliefLiquidOralChain Drug Consortium2013-10-04Not applicableUs
NightTime Cold and Cough ChildrenLiquidOralASSURED / DOLLAR TREE (Greenbrier International, Inc.)2017-08-31Not applicableUs
Nighttime Cold and Flu Maximum StrengthLiquidOralWalgreens2015-06-30Not applicableUs
Nighttime Cold and Flu Relief TherapyLiquidOralQuality Choice (Chain Drug Marketing Association, Inc.)2014-06-30Not applicableUs
Nighttime Cold and Flu-IN-one Extra StrengthTabletOralVita Health Products Inc2008-04-21Not applicableCanada
Nighttime Cold, Cough & FluCapsuleOralApotex CorporationNot applicableNot applicableCanada
Nighttime Flu and SeverePowder, for solutionOralTaro Pharmaceuticals U.S.A., Inc.2013-06-28Not applicableUs
Nighttime Flu Relief Therapy Severe ColdLiquidOralAmerisource Bergen (Good Neighbor Pharmacy) 461222015-08-31Not applicableUs
Nighttime Flu, Cough & Cold Complete Relief Extra StrengthTabletOralVita Health Products Inc2014-07-16Not applicableCanada
Nighttime Pain Plus SleepLiquidOralChain Drug Consortium2015-05-05Not applicableUs
Nighttime Pain ReliefCapsuleOralApotex CorporationNot applicableNot applicableCanada
Nighttime Pain RelieverCapsuleOralMarcan Pharmaceuticals IncNot applicableNot applicableCanada
NightTime Pain Reliever PMLiquidOralWalgreen2015-06-08Not applicableUs
Nighttime Severe Cough and ColdPowder, for solutionOralCardinal Health2017-03-03Not applicableUs
Nighttime Super Strength Contac CompleteTabletOralGlaxosmithkline Inc1997-07-082009-07-28Canada
Nighttime Symptom Relief Extra Strength for Symptoms Of Cold and CoughPowderOralPharmetics (2011) Inc.Not applicableNot applicableCanada
Nighttime Total Cold and FluTabletOralVita Health Products Inc2009-03-01Not applicableCanada
Nite Time Cold and CoughLiquidOralAccudial Pharmaceutical, Inc.2009-11-25Not applicableUs
Nite Time Cold and Cough ChildrensSolutionOralKroger2007-08-29Not applicableUs
Non Aspirin PM Extra StrengthTablet, coatedOralFred's2015-12-17Not applicableUs
Non-Aspirin PM Extra StrengthTablet, coatedOralNew World Imports2011-11-172017-08-11Us
Our Family night time severe cold and cough honey lemon infused with chamomile and white tea flavorsGranule, for solutionOralQuality Home Products2009-10-31Not applicableUs
Pain Away plus Sleep aidLiquidOralChain Drug Consortium2015-07-24Not applicableUs
Pain Plus SleepLiquidOralAmerisource Bergen2016-05-19Not applicableUs
Pain Relief Acetaminophen PM Extra StrengthTablet, film coatedOralRite Aid1994-05-15Not applicableUs
Pain Relief and Pain Relief PMKitMeijer Distribution2005-10-19Not applicableUs
Pain Relief Medicine PMTabletOralArmy + Air Force Exchange Service2004-06-07Not applicableUs
Pain Relief Pain Relief PMKitMeijer Distribution2013-12-06Not applicableUs
Pain Relief plus Sleep AidLiquidOralDolgencorp2016-02-29Not applicableUs
Pain Relief PMTabletOralTarget Corporation.2004-06-07Not applicableUs
Pain Relief PM Extra ReliefTabletOralGreenbrier International, Inc.2007-12-17Not applicableUs
Pain Relief PM Extra StrengthTabletOralWalgreens2013-10-30Not applicableUs
Pain Relief PM Extra Strength Aspirin FreeTablet, coatedOralSafeway2013-03-15Not applicableUs
Pain Relief PM Nightime Sleep AidTablet, coatedOralSelect Corporation2012-10-15Not applicableUs
Pain Relief PM Rapid ReleaseCapsule, coatedOralMeijer Distribution2010-07-09Not applicableUs
Pain Reliever Extra Strength PMTabletOralL&R Distributors, Inc.2007-12-17Not applicableUs
Pain Reliever PMTablet, film coatedOralNash Finch1994-05-15Not applicableUs
Pain Reliever PM Extra StrengthTablet, coatedOralWalgreens2013-05-31Not applicableUs
Pain Reliever Sleep Aid Extra strengthTablet, coatedOralFamily Dollar (FAMILY WELLNESS)2013-11-04Not applicableUs
Panadol PMTablet, film coatedOralGlaxo Smith Kline Consumer Healthcare Holdings (Us) Llc2011-03-232017-06-30Us
PediaCare Childrens Allergy and ColdLiquidOralBlacksmith Brands, Inc.2009-10-29Not applicableUs
PediaCare Childrens Nighttime Multi Symptom ColdLiquidOralMedtech Laboratories, Inc.2012-06-20Not applicableUs
Percogesic Extra StrengthCapsule, coatedOralMedtech Laboratories, Inc.2010-07-07Not applicableUs
Percogesic Original StrengthTablet, coatedOralMedtech Laboratories, Inc.2010-03-19Not applicableUs
Plus Pharma Extra Strength Acetaminophen PMTablet, film coatedOralGemini Pharmaceuticals, Inc. dba Plus Pharma2006-03-27Not applicableUs
PM AcetaminophenTabletOralNew World Imports2010-09-302017-08-11Us
PM Get ReliefTabletOralEagle Distributors,Inc.2012-06-30Not applicableUs
PM pain relieverTablet, film coatedOralRite Aid2004-06-072020-02-20Us
Preferred Plus Cold and Flu Night TimeTablet, film coatedOralKinray2014-12-03Not applicableUs
Preferred Plus Severe Cold Cough and FluPowder, for solutionOralKinray2014-09-22Not applicableUs
Preferred Plus Severe Cold Day Time Cold and Flu Night TimeKitKinray2015-02-28Not applicableUs
Preferred Plus Sinus Relief Day Tiime Night TimeKitKinray2014-12-03Not applicableUs
Premier Value AllergyCreamTopicalTAI GUK PHARM. CO., LTD.2010-09-17Not applicableUs
Premier Value night time severe cold and cough honey lemon infused with chamomile and white tea flavorsGranule, for solutionOralQuality Home Products2009-10-31Not applicableUs
Publix allergyCreamTopicalPublix Supermarkets, Inc.2005-09-20Not applicableUs
Pulmorex DM SyrSyrupOralProdemdis Enr.1988-12-312010-07-15Canada
Pulmorex Expectorant LiqSyrupOralNutribon (1986) Inc.1988-12-311996-09-30Canada
Quality Choice Extra Strength Anti ItchCreamTopicalChain Drug Marketing Association2012-02-13Not applicableUs
Quality Choice night time severe cold and cough honey lemon infused with chamomile and white tea flavorsGranule, for solutionOralQuality Home Products2009-10-31Not applicableUs
Quality Choice Nighttime Severe Cold and Cough Honey Lemon infused with Chamomile and White Tea FlavorsGranule, for solutionOralChain Drug Marketing Association2013-12-02Not applicableUs
Rapid Release Acetaminophen PM Extra StrengthTabletOralCostco Wholesale2007-12-17Not applicableUs
Rapid Release Pain Relief PMTabletOralMeijer Distribution2007-12-17Not applicableUs
Reeses Onetab Allergy and SinusTabletOralReese Pharmaceutical Company2010-04-05Not applicableUs
Reeses Onetab Cold and FluTabletOralReese Pharmaceutical Company2010-04-05Not applicableUs
Regular Strength Flu Relief NightimeTabletOralVita Health Products Inc2004-06-042011-07-20Canada
Rite Aid Maximum Strength Itch ReliefSprayTopicalRite Aid2011-08-10Not applicableUs
Rite Aid night time severe cold and cough honey lemon with chamomile and white tea flavorsGranule, for solutionOralQuality Home Products2009-10-31Not applicableUs
Rite Aid Nighttime Severe Cold and Cough ReliefPowder, for solutionOralRite Aid2013-06-28Not applicableUs
Robitussin Night Time Cough and ColdLiquidOralRichmond Division of Wyeth2006-02-092016-10-28Us
Robitussin Peak Cold Nighttime Multi-symptom ColdLiquidOralRichmond Division of Wyeth2011-06-15Not applicableUs
Robitussin Severe Multi-Symptom Cough Cold Flu NighttimeSolutionOralRichmond Division of Wyeth2015-07-01Not applicableUs
Rugby Acetaminophen 500 mg and Diphenhydramine HCl 25 mg Pain Reliever/Sleep AidTablet, film coatedOralRugby2014-08-26Not applicableUs
Rx Act Flu and Severe Cold and Cough NighttimePowder, for solutionOralH.E.B.2010-09-22Not applicableUs
Rx Act Ibuprofen PMTablet, coatedOralH.E.B.2009-03-11Not applicableUs
rx act Pain Relief PMTablet, film coatedOralH.E.B.1996-07-10Not applicableUs
Rx Act Pain Relief PM Extra Strengh Rapid ReleaseCapsule, coatedOralH.E.B.2010-08-26Not applicableUs
Salonpas Medicated PlasterPlasterTopicalHisamitsu Pharmaceutical Co., Inc.1955-12-312002-06-12Canada
SanaTos Severe Cold and Cough NighttimeGranule, for solutionOralPharmadel LLC2014-02-20Not applicableUs
Select Brand Itch ReliefSprayTopicalSelect Brand2012-07-11Not applicableUs
Severe AllergyTabletOralWalgreen2005-06-06Not applicableUs
Severe Allergy And Sinus HeadacheTabletOralRite Aid2007-06-272019-03-30Us
Severe Allergy And Sinus Headache Maximum StrengthTablet, film coatedOralCvs Health2007-06-27Not applicableUs
Severe Allergy Plus Sinus HeadacheTablet, coatedOralTop Care2013-07-01Not applicableUs
Severe Allergy Plus Sinus Headache Maximum StrengthTablet, coatedOralMeijer2011-08-012016-04-30Us
Severe Allergy Relief Plus Sinus HeadacheTablet, coatedOralChain Drug Marketing Association2012-02-22Not applicableUs
Severe ColdTablet, coatedOralChain Drug Marketing Association2012-07-24Not applicableUs
Severe Cold and Cough Night TimeLiquidOralDolgencorp, Inc. (Dollar General & Rexall)2015-06-30Not applicableUs
Severe Cold and Cough Relief NighttimeLiquidOralH.E.B.2015-10-31Not applicableUs
severe cold and sinus relief PETablet, film coatedOralRite Aid2005-06-21Not applicableUs
Severe Cold Cough and FluPowder, for solutionOralHyvee2015-01-11Not applicableUs
Severe Cold Cough and Flu Relief NighttimePowder, for solutionOralRite Aid2015-07-24Not applicableUs
Severe Cold Daytime Cold and Flu NighttimeKitWestern Family Foods2014-10-10Not applicableUs
Severe Cold PETablet, coatedOralSelect Brand2008-09-24Not applicableUs
Severe Cold PE Multi-SymptomTablet, film coatedOralSupervalu2005-06-21Not applicableUs
Severe Cold Relief PETablet, film coatedOralWoonsocket Prescription Center, Incorporated2005-06-21Not applicableUs
Severe Cold, Cold and Flu Maximum Strength, Daytime, NightimeKitCvs Health2017-07-01Not applicableUs
Severe Congestion and Cough, Cold and Flu Daytime and NighttimeKitRite Aid2015-07-20Not applicableUs
Severe Congestion and Cough, Cold and Flu Daytime, NighttimeKitCvs Health2017-07-01Not applicableUs
Severe Congestion and Cough/ Cold and Flu Daytime/nighttimeKitRite Aid2015-07-20Not applicableUs
Severe Congestion and Cough/Cold and Flu Daytime/Nighttime/Maximum StrengthKitCvs Health2015-07-01Not applicableUs
Severe Cough and ColdPowder, for solutionOralCvs Health2010-09-14Not applicableUs
Shopko Anti-ItchCreamTopicalShopko Stores Operating2005-09-20Not applicableUs
ShopRight Childrens Nighttime Cold and CoughLiquidOralWakfern Food Corporation2013-07-02Not applicableUs
ShopRite Anti ItchCreamTopicalWakfern Food Corporation2013-11-18Not applicableUs
Shoprite Ibuprofen PMTablet, coatedOralWakfern Food Corporation2013-06-11Not applicableUs
ShopRite Nighttime Flu Plus Severe Cold and CoughPowder, for solutionOralWakfern Food Corporation2013-06-28Not applicableUs
ShopRite Non AspirinTablet, film coatedOralWakfern Food Corporation2016-01-19Not applicableUs
ShopRite Pain Relief PMTablet, film coatedOralWakfern Food Corporation2013-07-17Not applicableUs
Signature Care Ibuprofen PMTablet, coatedOralSafeway2015-09-01Not applicableUs
Signature Care Itch ReliefCreamTopicalSafeway2015-09-01Not applicableUs
Signature Care severe cold cough and flu NighttimePowder, for solutionOralSafeway2015-10-27Not applicableUs
Sinus ReliefKitKroger2015-04-10Not applicableUs
Sinus Relief Congestion and Cough Maximum StrengthLiquidOralWalgreens2015-06-30Not applicableUs
Sinus Relief Daytime, Nighttime, Maximum StrengthKitCvs Health2017-07-01Not applicableUs
Sinus Relief Maximum Strength Daytime and Nighttime Sinus PainKitCvs Health2013-06-30Not applicableUs
Sinus Relief Nightime CapletsTabletOralPharmetics (2011) Inc.Not applicableNot applicableCanada
Sinutab Daytime/nightime Extra Strength Caplets (combo Pack)TabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Sinutab N.T. Extra Strength CapletsTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc1998-03-05Not applicableCanada
Sinutab N.T. Regular Strength CapletsTabletOralWarner Lambert Canada Inc.1996-02-021999-08-13Canada
Sinutab PE Sinus and AllergyTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Smart Sense Anti Itch Extra StrengthCreamTopicalKmart Corporation2011-02-16Not applicableUs
Smart Sense Childrens Nighttime Cold and CoughSolutionOralKmart Corporation2014-04-18Not applicableUs
Smart Sense Flu and Severe Cold and Cough NighttimePowder, for solutionOralKmart Corporation2010-11-15Not applicableUs
Smart Sense Ibuprofen PMTablet, coatedOralKmart Corporation2010-05-27Not applicableUs
Smart Sense Itch StoppingCreamTopicalKmart Corporation2015-12-23Not applicableUs
Smart sense Nighttime Severe Cold and Cough Honey Lemon infused with Chamomile and White Tea FlavorsGranule, for solutionOralQuality Home Products2013-11-19Not applicableUs
Smart Sense Pain Relief PM Extra StrengthCapsule, coatedOralKmart Corporation2010-07-09Not applicableUs
Smart Sense Sinus ReliefKitKmart Corporation2015-12-29Not applicableUs
Smart Sense Topical Analgesic Skin ProtectantCreamTopicalKmart Corporation2013-12-13Not applicableUs
Smart Sense TriactingLiquidOralKmart Corporation2011-01-26Not applicableUs
SohMed Pain Relief PMTabletOralSOHM Inc.2013-08-25Not applicableUs
Sound Body Pain Relief PMTabletOralAllegiant Health2014-12-23Not applicableUs
Sting Kure - LiqLiquidTopicalWisconsin Pharmacal Company1995-12-312005-08-17Canada
Sting-eze-liqLiquidTopicalWisconsin Pharmacal Company1995-12-312002-04-01Canada
Sudafed PE Cold and CoughTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson IncNot applicableNot applicableCanada
Sudafed PE Day Plus Night Sinus CongestionKitJohnson & Johnson Consumer Inc., Mc Neil Consumer Healthcare Division2017-06-26Not applicableUs
Sudafed Sinus NighttimeTabletOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2015-05-13Not applicableCanada
Sunmark Anti-itchCreamTopicalMc Kesson2005-09-20Not applicableUs
Sunmark Ibuprofen PMTablet, coatedOralMc Kesson2009-02-18Not applicableUs
Sunmark Pain Reliever PM Extra StrengthTablet, film coatedOralMc Kesson2003-08-11Not applicableUs
Suphedrine PETablet, film coatedOralTarget Corporation.2005-06-21Not applicableUs
Suppress Cough Syr W.cod.diphen.hcl Amm.chl.SyrupOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1996-12-312002-07-31Canada
TactCreamTopicalSato Pharmaceutical Inc., Ltd.1997-09-09Not applicableUs
Tact Cool JellyGelTopicalSato Pharmaceutical1997-10-02Not applicableUs
Tecnu CalagelGelTopicalTec Laboratories, Inc.1992-10-09Not applicableUs
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Texaclear Night Time Cough Cold/fluLiquidOralGm Pharmaceuticals2014-10-23Not applicableUs
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Categories
UNII8GTS82S83M
CAS number58-73-1
WeightAverage: 255.3547
Monoisotopic: 255.162314299
Chemical FormulaC17H21NO
InChI KeyZZVUWRFHKOJYTH-UHFFFAOYSA-N
InChI
InChI=1S/C17H21NO/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3-12,17H,13-14H2,1-2H3
IUPAC Name
[2-(diphenylmethoxy)ethyl]dimethylamine
SMILES
CN(C)CCOC(C1=CC=CC=C1)C1=CC=CC=C1
Pharmacology
Indication

For the treatment of symptoms associated with Vertigo/Meniere's disease, nausea and vomiting, motion sickness and insect bite.

Structured Indications
Pharmacodynamics

Diphenhydramine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, diphenhydramine competes with free histamine for binding at HA-receptor sites. Diphenhydramine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of diphenhydramine. This anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown.

Mechanism of action

Diphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding.

TargetKindPharmacological actionActionsOrganismUniProt ID
Histamine H1 receptorProteinyes
antagonist
HumanP35367 details
Muscarinic acetylcholine receptor M2Proteinunknown
antagonist
HumanP08172 details
Related Articles
Absorption

Quickly absorbed with maximum activity occurring in approximately one hour.

Volume of distributionNot Available
Protein binding

98 to 99%

Metabolism

Hepatic and renal

SubstrateEnzymesProduct
Diphenhydramine
N-DesmethyldiphenhydramineDetails
Diphenhydramine
Diphenhydramine N-glucuronideDetails
N-Desmethyldiphenhydramine
N,N-DidesmethyldiphenhydramineDetails
N,N-Didesmethyldiphenhydramine
Not Available
Diphenylmethoxyacetic acidDetails
Route of elimination

Little, if any, is excreted unchanged in the urine; most appears as the degradation products of metabolic transformation in the liver, which are almost completely excreted within 24 hours.

Half life

1-4 hours

ClearanceNot Available
Toxicity

LD50=500 mg/kg (orally in rats). Considerable overdosage can lead to myocardial infarction (heart attack), serious ventricular dysrhythmias, coma and death.

Affected organisms
  • Humans and other mammals
PathwaysNot Available
Pharmacogenomic Effects/ADRs Not Available
Interactions
Drug Interactions
DrugInteractionDrug group
2,5-Dimethoxy-4-ethylamphetamine2,5-Dimethoxy-4-ethylamphetamine may decrease the sedative activities of Diphenhydramine.Experimental, Illicit
3,4-Methylenedioxyamphetamine3,4-Methylenedioxyamphetamine may decrease the sedative activities of Diphenhydramine.Experimental, Illicit
3,4-Methylenedioxymethamphetamine3,4-Methylenedioxymethamphetamine may decrease the sedative activities of Diphenhydramine.Experimental, Illicit
4-Bromo-2,5-dimethoxyamphetamine4-Bromo-2,5-dimethoxyamphetamine may decrease the sedative activities of Diphenhydramine.Experimental, Illicit
4-MethoxyamphetamineThe metabolism of 4-Methoxyamphetamine can be decreased when combined with Diphenhydramine.Experimental, Illicit
7-NitroindazoleThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with 7-Nitroindazole.Experimental
AbirateroneThe serum concentration of Diphenhydramine can be increased when it is combined with Abiraterone.Approved
AcepromazineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Acepromazine.Approved, Vet Approved
AceprometazineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Aceprometazine.Approved
AcetaminophenThe metabolism of Acetaminophen can be decreased when combined with Diphenhydramine.Approved
AcetylcholineThe metabolism of Acetylcholine can be decreased when combined with Diphenhydramine.Approved
AdipiplonThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with adipiplon.Investigational
AgomelatineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Agomelatine.Approved, Investigational
AjmalineThe metabolism of Ajmaline can be decreased when combined with Diphenhydramine.Approved
AlfaxaloneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Alfaxalone.Vet Approved
AlfentanilThe risk or severity of adverse effects can be increased when Alfentanil is combined with Diphenhydramine.Approved, Illicit
AllopregnanoloneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Sage 547.Investigational
AlmotriptanThe metabolism of Almotriptan can be decreased when combined with Diphenhydramine.Approved, Investigational
AlogliptinThe metabolism of Alogliptin can be decreased when combined with Diphenhydramine.Approved
AlphacetylmethadolThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Alphacetylmethadol.Experimental, Illicit
AlprazolamThe risk or severity of adverse effects can be increased when Alprazolam is combined with Diphenhydramine.Approved, Illicit, Investigational
AlprenololThe metabolism of Alprenolol can be decreased when combined with Diphenhydramine.Approved, Withdrawn
AminophenazoneThe metabolism of Aminophenazone can be decreased when combined with Diphenhydramine.Approved, Withdrawn
AmiodaroneDiphenhydramine may increase the QTc-prolonging activities of Amiodarone.Approved, Investigational
AmisulprideThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Amisulpride.Approved, Investigational
AmitriptylineThe metabolism of Amitriptyline can be decreased when combined with Diphenhydramine.Approved
AmobarbitalThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Amobarbital.Approved, Illicit
AmoxapineThe metabolism of Amoxapine can be decreased when combined with Diphenhydramine.Approved
AmperozideThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Amperozide.Experimental
AmphetamineThe metabolism of Amphetamine can be decreased when combined with Diphenhydramine.Approved, Illicit
AmprenavirThe metabolism of Amprenavir can be decreased when combined with Diphenhydramine.Approved
AmsacrineThe metabolism of Amsacrine can be decreased when combined with Diphenhydramine.Approved
AnagrelideDiphenhydramine may increase the QTc-prolonging activities of Anagrelide.Approved
AntipyrineThe metabolism of Antipyrine can be decreased when combined with Diphenhydramine.Approved
AprepitantThe metabolism of Diphenhydramine can be increased when combined with Aprepitant.Approved, Investigational
AprindineThe metabolism of Aprindine can be decreased when combined with Diphenhydramine.Approved
ArformoterolThe metabolism of Arformoterol can be decreased when combined with Diphenhydramine.Approved, Investigational
AripiprazoleThe serum concentration of Aripiprazole can be increased when it is combined with Diphenhydramine.Approved, Investigational
ArmodafinilThe metabolism of Diphenhydramine can be decreased when combined with Armodafinil.Approved, Investigational
Arsenic trioxideDiphenhydramine may increase the QTc-prolonging activities of Arsenic trioxide.Approved, Investigational
ArtemetherDiphenhydramine may increase the QTc-prolonging activities of Artemether.Approved
ArticaineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Articaine.Approved
AsenapineDiphenhydramine may increase the QTc-prolonging activities of Asenapine.Approved
AstemizoleThe metabolism of Astemizole can be decreased when combined with Diphenhydramine.Approved, Withdrawn
AtomoxetineThe metabolism of Diphenhydramine can be decreased when combined with Atomoxetine.Approved
AzaperoneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Azaperone.Vet Approved
AzelastineDiphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.Approved
AzelastineThe metabolism of Azelastine can be decreased when combined with Diphenhydramine.Approved
AzithromycinDiphenhydramine may increase the QTc-prolonging activities of Azithromycin.Approved
BaclofenThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Baclofen.Approved
BarbitalThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Barbital.Illicit
BedaquilineDiphenhydramine may increase the QTc-prolonging activities of Bedaquiline.Approved
BenperidolThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Benperidol.Investigational
BenzatropineThe metabolism of Benzatropine can be decreased when combined with Diphenhydramine.Approved
BenzocaineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Benzocaine.Approved
BenzphetamineBenzphetamine may decrease the sedative activities of Diphenhydramine.Approved, Illicit
Benzyl alcoholThe metabolism of Benzyl alcohol can be decreased when combined with Diphenhydramine.Approved
Benzylpenicilloyl PolylysineDiphenhydramine may decrease effectiveness of Benzylpenicilloyl Polylysine as a diagnostic agent.Approved
BepridilThe metabolism of Bepridil can be decreased when combined with Diphenhydramine.Approved, Withdrawn
BetahistineThe therapeutic efficacy of Betahistine can be decreased when used in combination with Diphenhydramine.Approved
BetaxololThe metabolism of Diphenhydramine can be decreased when combined with Betaxolol.Approved
BisoprololThe metabolism of Bisoprolol can be decreased when combined with Diphenhydramine.Approved
BortezomibThe metabolism of Diphenhydramine can be decreased when combined with Bortezomib.Approved, Investigational
BrexpiprazoleThe serum concentration of Brexpiprazole can be increased when it is combined with Diphenhydramine.Approved
BrimonidineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Brimonidine.Approved
BrimonidineBrimonidine may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine.Approved
BromazepamThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Bromazepam.Approved, Illicit
BrompheniramineThe metabolism of Brompheniramine can be decreased when combined with Diphenhydramine.Approved
BrotizolamThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Brotizolam.Approved, Withdrawn
BufuralolThe metabolism of Bufuralol can be decreased when combined with Diphenhydramine.Experimental, Investigational
BupivacaineThe metabolism of Bupivacaine can be decreased when combined with Diphenhydramine.Approved, Investigational
BuprenorphineDiphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.Approved, Illicit, Investigational, Vet Approved
BupropionThe metabolism of Diphenhydramine can be decreased when combined with Bupropion.Approved
BuspironeThe metabolism of Buspirone can be decreased when combined with Diphenhydramine.Approved, Investigational
ButabarbitalThe risk or severity of adverse effects can be increased when Butabarbital is combined with Diphenhydramine.Approved, Illicit
ButacaineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Butacaine.Vet Approved
ButalbitalThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Butalbital.Approved, Illicit
ButambenThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Butamben.Approved
ButethalThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Butethal.Approved, Illicit
ButorphanolThe risk or severity of adverse effects can be increased when Butorphanol is combined with Diphenhydramine.Approved, Illicit, Vet Approved
CaffeineThe metabolism of Diphenhydramine can be decreased when combined with Caffeine.Approved
CapecitabineThe metabolism of Diphenhydramine can be decreased when combined with Capecitabine.Approved, Investigational
CaptoprilThe metabolism of Captopril can be decreased when combined with Diphenhydramine.Approved
CarbamazepineThe metabolism of Diphenhydramine can be increased when combined with Carbamazepine.Approved, Investigational
CarbinoxamineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Carbinoxamine.Approved
CarfentanilThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Carfentanil.Illicit, Vet Approved
CariprazineThe metabolism of Cariprazine can be decreased when combined with Diphenhydramine.Approved
CarisoprodolThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Carisoprodol.Approved
CarteololThe metabolism of Carteolol can be decreased when combined with Diphenhydramine.Approved
CarvedilolThe metabolism of Carvedilol can be decreased when combined with Diphenhydramine.Approved, Investigational
CelecoxibThe metabolism of Diphenhydramine can be decreased when combined with Celecoxib.Approved, Investigational
CephalexinThe metabolism of Cephalexin can be decreased when combined with Diphenhydramine.Approved, Vet Approved
CeritinibThe serum concentration of Diphenhydramine can be increased when it is combined with Ceritinib.Approved
CetirizineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Cetirizine.Approved
CevimelineThe metabolism of Cevimeline can be decreased when combined with Diphenhydramine.Approved
Chloral hydrateThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Chloral hydrate.Approved, Illicit, Vet Approved
ChloramphenicolThe metabolism of Diphenhydramine can be decreased when combined with Chloramphenicol.Approved, Vet Approved
ChlordiazepoxideThe metabolism of Chlordiazepoxide can be decreased when combined with Diphenhydramine.Approved, Illicit
ChlormezanoneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Chlormezanone.Approved, Withdrawn
ChloroprocaineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Chloroprocaine.Approved
ChloroquineDiphenhydramine may increase the QTc-prolonging activities of Chloroquine.Approved, Vet Approved
ChlorphenamineThe metabolism of Chlorphenamine can be decreased when combined with Diphenhydramine.Approved
ChlorphentermineChlorphentermine may decrease the sedative activities of Diphenhydramine.Illicit, Withdrawn
ChlorpromazineDiphenhydramine may increase the QTc-prolonging activities of Chlorpromazine.Approved, Vet Approved
ChlorprothixeneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Chlorprothixene.Approved, Withdrawn
ChlorzoxazoneThe metabolism of Chlorzoxazone can be decreased when combined with Diphenhydramine.Approved
CholecalciferolThe metabolism of Diphenhydramine can be decreased when combined with Cholecalciferol.Approved, Nutraceutical
CilostazolThe metabolism of Cilostazol can be decreased when combined with Diphenhydramine.Approved
CimetidineThe metabolism of Diphenhydramine can be decreased when combined with Cimetidine.Approved
CinacalcetThe metabolism of Diphenhydramine can be decreased when combined with Cinacalcet.Approved
CinchocaineThe risk or severity of adverse effects can be increased when Cinchocaine is combined with Diphenhydramine.Approved, Vet Approved
CinnarizineThe metabolism of Cinnarizine can be decreased when combined with Diphenhydramine.Approved
CiprofloxacinDiphenhydramine may increase the QTc-prolonging activities of Ciprofloxacin.Approved, Investigational
CisaprideDiphenhydramine may increase the QTc-prolonging activities of Cisapride.Approved, Investigational, Withdrawn
CitalopramDiphenhydramine may increase the QTc-prolonging activities of Citalopram.Approved
ClarithromycinDiphenhydramine may increase the QTc-prolonging activities of Clarithromycin.Approved
ClemastineThe metabolism of Diphenhydramine can be decreased when combined with Clemastine.Approved
ClevidipineThe metabolism of Clevidipine can be decreased when combined with Diphenhydramine.Approved
ClidiniumThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Clidinium.Approved
ClobazamThe metabolism of Diphenhydramine can be decreased when combined with Clobazam.Approved, Illicit
clomethiazoleThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with clomethiazole.Investigational
ClomipramineThe metabolism of Clomipramine can be decreased when combined with Diphenhydramine.Approved, Vet Approved
ClonazepamThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Clonazepam.Approved, Illicit
ClonidineThe metabolism of Clonidine can be decreased when combined with Diphenhydramine.Approved
ClopidogrelThe metabolism of Diphenhydramine can be decreased when combined with Clopidogrel.Approved, Nutraceutical
ClorazepateThe risk or severity of adverse effects can be increased when Clorazepate is combined with Diphenhydramine.Approved, Illicit
ClotrimazoleThe metabolism of Diphenhydramine can be decreased when combined with Clotrimazole.Approved, Vet Approved
ClozapineDiphenhydramine may increase the QTc-prolonging activities of Clozapine.Approved
CobicistatThe serum concentration of Diphenhydramine can be increased when it is combined with Cobicistat.Approved
CocaineThe metabolism of Diphenhydramine can be decreased when combined with Cocaine.Approved, Illicit
CodeineThe therapeutic efficacy of Codeine can be decreased when used in combination with Diphenhydramine.Approved, Illicit
CrizotinibDiphenhydramine may increase the QTc-prolonging activities of Crizotinib.Approved
CyclizineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Cyclizine.Approved
CyclobenzaprineThe metabolism of Cyclobenzaprine can be decreased when combined with Diphenhydramine.Approved
CyclophosphamideThe metabolism of Cyclophosphamide can be decreased when combined with Diphenhydramine.Approved, Investigational
CyclosporineThe metabolism of Diphenhydramine can be decreased when combined with Cyclosporine.Approved, Investigational, Vet Approved
CyproheptadineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Cyproheptadine.Approved
Cyproterone acetateThe serum concentration of Diphenhydramine can be decreased when it is combined with Cyproterone acetate.Approved, Investigational
DabrafenibThe serum concentration of Diphenhydramine can be decreased when it is combined with Dabrafenib.Approved
DantroleneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Dantrolene.Approved
DapagliflozinThe metabolism of Dapagliflozin can be decreased when combined with Diphenhydramine.Approved
DapiprazoleThe risk or severity of adverse effects can be increased when Dapiprazole is combined with Diphenhydramine.Approved
DapoxetineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Dapoxetine.Investigational
DarifenacinThe metabolism of Diphenhydramine can be decreased when combined with Darifenacin.Approved, Investigational
DarunavirThe serum concentration of Diphenhydramine can be increased when it is combined with Darunavir.Approved
DasabuvirThe metabolism of Dasabuvir can be decreased when combined with Diphenhydramine.Approved
DebrisoquinThe metabolism of Debrisoquin can be decreased when combined with Diphenhydramine.Approved
DeferasiroxThe serum concentration of Diphenhydramine can be increased when it is combined with Deferasirox.Approved, Investigational
DelavirdineThe metabolism of Diphenhydramine can be decreased when combined with Delavirdine.Approved
DeramciclaneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with deramciclane.Investigational
DesfluraneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Desflurane.Approved
DesipramineThe metabolism of Desipramine can be decreased when combined with Diphenhydramine.Approved
DesloratadineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Desloratadine.Approved, Investigational
DesvenlafaxineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Desvenlafaxine.Approved
DetomidineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Detomidine.Vet Approved
DexbrompheniramineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Dexbrompheniramine.Approved
DexfenfluramineThe metabolism of Dexfenfluramine can be decreased when combined with Diphenhydramine.Approved, Illicit, Withdrawn
DexmedetomidineThe risk or severity of adverse effects can be increased when Dexmedetomidine is combined with Diphenhydramine.Approved, Vet Approved
DexmethylphenidateThe metabolism of Dexmethylphenidate can be decreased when combined with Diphenhydramine.Approved
DextroamphetamineThe metabolism of Dextroamphetamine can be decreased when combined with Diphenhydramine.Approved, Illicit
DextromethorphanThe metabolism of Dextromethorphan can be decreased when combined with Diphenhydramine.Approved
DextromoramideThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Dextromoramide.Experimental, Illicit
DextropropoxypheneThe risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with Diphenhydramine.Approved, Illicit, Withdrawn
DezocineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Dezocine.Approved
DiazepamThe risk or severity of adverse effects can be increased when Diazepam is combined with Diphenhydramine.Approved, Illicit, Vet Approved
DiethylpropionDiethylpropion may decrease the sedative activities of Diphenhydramine.Approved, Illicit
DifenoxinThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Difenoxin.Approved, Illicit
DihydrocodeineThe metabolism of Dihydrocodeine can be decreased when combined with Diphenhydramine.Approved, Illicit
DihydroetorphineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Dihydroetorphine.Experimental, Illicit
DihydromorphineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Dihydromorphine.Experimental, Illicit
DiltiazemThe metabolism of Diltiazem can be decreased when combined with Diphenhydramine.Approved
DimenhydrinateThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Dimenhydrinate.Approved
DiphenoxylateThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Diphenoxylate.Approved, Illicit
DisopyramideDiphenhydramine may increase the QTc-prolonging activities of Disopyramide.Approved
DofetilideDiphenhydramine may increase the QTc-prolonging activities of Dofetilide.Approved
DolasetronDiphenhydramine may increase the QTc-prolonging activities of Dolasetron.Approved
DomperidoneDiphenhydramine may increase the QTc-prolonging activities of Domperidone.Approved, Investigational, Vet Approved
DonepezilThe metabolism of Donepezil can be decreased when combined with Diphenhydramine.Approved
DopamineThe metabolism of Dopamine can be decreased when combined with Diphenhydramine.Approved
DoramectinThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Doramectin.Vet Approved
DoxazosinThe metabolism of Doxazosin can be decreased when combined with Diphenhydramine.Approved
DoxepinThe metabolism of Doxepin can be decreased when combined with Diphenhydramine.Approved
DoxorubicinThe serum concentration of Doxorubicin can be increased when it is combined with Diphenhydramine.Approved, Investigational
DoxorubicinThe metabolism of Doxorubicin can be decreased when combined with Diphenhydramine.Approved, Investigational
DoxylamineDoxylamine may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine.Approved, Vet Approved
DPDPEThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with DPDPE.Investigational
DronabinolDronabinol may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine.Approved, Illicit
DronedaroneDiphenhydramine may increase the QTc-prolonging activities of Dronedarone.Approved
DroperidolDroperidol may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine.Approved, Vet Approved
DrotebanolThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Drotebanol.Experimental, Illicit
DuloxetineThe metabolism of Diphenhydramine can be decreased when combined with Duloxetine.Approved
DyclonineThe risk or severity of adverse effects can be increased when Dyclonine is combined with Diphenhydramine.Approved
EcgonineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Ecgonine.Experimental, Illicit
EcopipamThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Ecopipam.Investigational
EfavirenzThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Efavirenz.Approved, Investigational
EletriptanThe metabolism of Eletriptan can be decreased when combined with Diphenhydramine.Approved, Investigational
EliglustatThe serum concentration of Eliglustat can be increased when it is combined with Diphenhydramine.Approved
EltanoloneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Pregnanolone.Investigational
EncainideThe metabolism of Encainide can be decreased when combined with Diphenhydramine.Approved, Withdrawn
EnclomipheneThe metabolism of Enclomiphene can be decreased when combined with Diphenhydramine.Investigational
EnfluraneThe risk or severity of adverse effects can be increased when Enflurane is combined with Diphenhydramine.Approved, Vet Approved
EntacaponeThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Entacapone.Approved, Investigational
EpinastineThe metabolism of Epinastine can be decreased when combined with Diphenhydramine.Approved, Investigational
ErlotinibThe metabolism of Erlotinib can be decreased when combined with Diphenhydramine.Approved, Investigational
ErythromycinDiphenhydramine may increase the QTc-prolonging activities of Erythromycin.Approved, Vet Approved
EscitalopramDiphenhydramine may increase the QTc-prolonging activities of Escitalopram.Approved, Investigational
Eslicarbazepine acetateThe metabolism of Diphenhydramine can be decreased when combined with Eslicarbazepine acetate.Approved
EsmirtazapineThe metabolism of Esmirtazapine can be decreased when combined with Diphenhydramine.Investigational
EsomeprazoleThe metabolism of Diphenhydramine can be decreased when combined with Esomeprazole.Approved, Investigational
EstazolamThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Estazolam.Approved, Illicit
EszopicloneThe risk or severity of adverse effects can be increased when Eszopiclone is combined with Diphenhydramine.Approved
EthanolDiphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.Approved
EthchlorvynolThe risk or severity of adverse effects can be increased when Ethchlorvynol is combined with Diphenhydramine.Approved, Illicit, Withdrawn
EthosuximideThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Ethosuximide.Approved
EthotoinThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Ethotoin.Approved
Ethyl carbamateThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Ethyl carbamate.Withdrawn
Ethyl loflazepateThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Ethyl loflazepate.Approved, Illicit
EthylmorphineThe metabolism of Ethylmorphine can be decreased when combined with Diphenhydramine.Approved, Illicit
EtidocaineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Etidocaine.Approved
EtifoxineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Etifoxine.Withdrawn
EtizolamThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Etizolam.Approved
EtomidateThe risk or severity of adverse effects can be increased when Etomidate is combined with Diphenhydramine.Approved
EtoperidoneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Etoperidone.Approved
EtoricoxibThe metabolism of Etoricoxib can be decreased when combined with Diphenhydramine.Approved, Investigational
EtorphineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Etorphine.Illicit, Vet Approved
EtravirineThe metabolism of Diphenhydramine can be decreased when combined with Etravirine.Approved
EzogabineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Ezogabine.Approved
FelbamateThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Felbamate.Approved
FencamfamineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Fencamfamine.Approved, Illicit, Withdrawn
FentanylThe risk or severity of adverse effects can be increased when Fentanyl is combined with Diphenhydramine.Approved, Illicit, Investigational, Vet Approved
FesoterodineThe serum concentration of the active metabolites of Fesoterodine can be increased when Fesoterodine is used in combination with Diphenhydramine.Approved
FexofenadineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Fexofenadine.Approved
FingolimodThe metabolism of Fingolimod can be decreased when combined with Diphenhydramine.Approved, Investigational
FlecainideDiphenhydramine may increase the QTc-prolonging activities of Flecainide.Approved, Withdrawn
FlibanserinThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Flibanserin.Approved
FloxuridineThe metabolism of Diphenhydramine can be decreased when combined with Floxuridine.Approved
FluconazoleThe metabolism of Diphenhydramine can be decreased when combined with Fluconazole.Approved
FludiazepamThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Fludiazepam.Approved, Illicit
FlunarizineThe metabolism of Flunarizine can be decreased when combined with Diphenhydramine.Approved
FlunitrazepamThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Flunitrazepam.Approved, Illicit
FluorouracilThe metabolism of Diphenhydramine can be decreased when combined with Fluorouracil.Approved
FluoxetineDiphenhydramine may increase the QTc-prolonging activities of Fluoxetine.Approved, Vet Approved
FlupentixolDiphenhydramine may increase the QTc-prolonging activities of Flupentixol.Approved, Withdrawn
FluphenazineThe metabolism of Fluphenazine can be decreased when combined with Diphenhydramine.Approved
FlurazepamThe risk or severity of adverse effects can be increased when Flurazepam is combined with Diphenhydramine.Approved, Illicit
FluspirileneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Fluspirilene.Approved
Fluticasone propionateThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Fluticasone Propionate.Approved
FluvastatinThe metabolism of Fluvastatin can be decreased when combined with Diphenhydramine.Approved
FluvoxamineThe metabolism of Diphenhydramine can be decreased when combined with Fluvoxamine.Approved, Investigational
FormoterolThe metabolism of Formoterol can be decreased when combined with Diphenhydramine.Approved, Investigational
FosphenytoinThe metabolism of Diphenhydramine can be increased when combined with Fosphenytoin.Approved
FospropofolThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Fospropofol.Approved, Illicit
GabapentinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Diphenhydramine.Approved, Investigational
Gabapentin EnacarbilThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with gabapentin enacarbil.Approved
Gadobenic acidDiphenhydramine may increase the QTc-prolonging activities of Gadobenic acid.Approved
GalantamineThe metabolism of Galantamine can be decreased when combined with Diphenhydramine.Approved
Gamma Hydroxybutyric AcidThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Gamma Hydroxybutyric Acid.Approved, Illicit
GefitinibThe metabolism of Gefitinib can be decreased when combined with Diphenhydramine.Approved, Investigational
GemfibrozilThe metabolism of Diphenhydramine can be decreased when combined with Gemfibrozil.Approved
GemifloxacinDiphenhydramine may increase the QTc-prolonging activities of Gemifloxacin.Approved, Investigational
GepironeThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Gepirone.Investigational
GlutethimideThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Glutethimide.Approved, Illicit
GoserelinDiphenhydramine may increase the QTc-prolonging activities of Goserelin.Approved
GranisetronDiphenhydramine may increase the QTc-prolonging activities of Granisetron.Approved, Investigational
GuanfacineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Guanfacine.Approved, Investigational
HalazepamThe risk or severity of adverse effects can be increased when Halazepam is combined with Diphenhydramine.Approved, Illicit, Withdrawn
HalofantrineThe metabolism of Halofantrine can be decreased when combined with Diphenhydramine.Approved
HaloperidolDiphenhydramine may increase the QTc-prolonging activities of Haloperidol.Approved
HalothaneThe metabolism of Halothane can be decreased when combined with Diphenhydramine.Approved, Vet Approved
HeroinThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Heroin.Approved, Illicit
HexobarbitalThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Hexobarbital.Approved
HyaluronidaseThe therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Diphenhydramine.Approved, Investigational
HydrocodoneDiphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.Approved, Illicit
HydromorphoneThe metabolism of Hydromorphone can be decreased when combined with Diphenhydramine.Approved, Illicit
HydroxyamphetamineHydroxyamphetamine hydrobromide may decrease the sedative activities of Diphenhydramine.Approved
HydroxyzineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine.Approved
IbrutinibThe metabolism of Ibrutinib can be decreased when combined with Diphenhydramine.Approved
IbutilideDiphenhydramine may increase the QTc-prolonging activities of Ibutilide.Approved
IdarubicinThe metabolism of Idarubicin can be decreased when combined with Diphenhydramine.Approved
IloperidoneDiphenhydramine may increase the QTc-prolonging activities of Iloperidone.Approved
ImatinibThe metabolism of Imatinib can be decreased when combined with Diphenhydramine.Approved
ImipramineThe metabolism of Diphenhydramine can be decreased when combined with Imipramine.Approved
IndalpineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Indalpine.Investigational, Withdrawn
IndinavirThe metabolism of Diphenhydramine can be decreased when combined with Indinavir.Approved
Ipratropium bromideThe metabolism of Ipratropium bromide can be decreased when combined with Diphenhydramine.Approved
IrbesartanThe metabolism of Diphenhydramine can be decreased when combined with Irbesartan.Approved, Investigational
IsofluraneThe risk or severity of adverse effects can be increased when Isoflurane is combined with Diphenhydramine.Approved, Vet Approved
IsoniazidThe metabolism of Diphenhydramine can be decreased when combined with Isoniazid.Approved
IxazomibThe metabolism of Ixazomib can be decreased when combined with Diphenhydramine.Approved
KetamineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Ketamine.Approved, Vet Approved
KetazolamThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Ketazolam.Approved
KetobemidoneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Ketobemidone.Approved
KetoconazoleThe metabolism of Diphenhydramine can be decreased when combined with Ketoconazole.Approved, Investigational
LabetalolThe metabolism of Labetalol can be decreased when combined with Diphenhydramine.Approved
LamotrigineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Lamotrigine.Approved, Investigational
LeflunomideThe metabolism of Diphenhydramine can be decreased when combined with Leflunomide.Approved, Investigational
LenvatinibDiphenhydramine may increase the QTc-prolonging activities of Lenvatinib.Approved
LeuprolideDiphenhydramine may increase the QTc-prolonging activities of Leuprolide.Approved, Investigational
LevetiracetamThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Levetiracetam.Approved, Investigational
LevobupivacaineThe risk or severity of adverse effects can be increased when Levobupivacaine is combined with Diphenhydramine.Approved
LevocabastineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Levocabastine.Approved
LevocetirizineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Levocetirizine.Approved
LevodopaThe metabolism of Levodopa can be decreased when combined with Diphenhydramine.Approved
LevofloxacinDiphenhydramine may increase the QTc-prolonging activities of Levofloxacin.Approved, Investigational
Levomethadyl AcetateThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Levomethadyl Acetate.Approved
LevomilnacipranThe metabolism of Levomilnacipran can be decreased when combined with Diphenhydramine.Approved
LevorphanolThe risk or severity of adverse effects can be increased when Levorphanol is combined with Diphenhydramine.Approved
LidocaineThe metabolism of Diphenhydramine can be decreased when combined with Lidocaine.Approved, Vet Approved
LisdexamfetamineLisdexamfetamine may decrease the sedative activities of Diphenhydramine.Approved, Investigational
LisurideThe metabolism of Lisuride can be decreased when combined with Diphenhydramine.Approved
LithiumThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Lithium.Approved
LofentanilThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Lofentanil.Illicit
LomustineThe metabolism of Lomustine can be decreased when combined with Diphenhydramine.Approved
LoperamideThe metabolism of Loperamide can be decreased when combined with Diphenhydramine.Approved
LopinavirDiphenhydramine may increase the QTc-prolonging activities of Lopinavir.Approved
LoratadineThe metabolism of Loratadine can be decreased when combined with Diphenhydramine.Approved
LorazepamThe risk or severity of adverse effects can be increased when Lorazepam is combined with Diphenhydramine.Approved
LorcaserinThe metabolism of Lorcaserin can be decreased when combined with Diphenhydramine.Approved
LosartanThe metabolism of Diphenhydramine can be decreased when combined with Losartan.Approved
LovastatinThe metabolism of Diphenhydramine can be decreased when combined with Lovastatin.Approved, Investigational
LoxapineThe risk or severity of adverse effects can be increased when Loxapine is combined with Diphenhydramine.Approved
LuliconazoleThe serum concentration of Diphenhydramine can be increased when it is combined with Luliconazole.Approved
LumacaftorThe serum concentration of Diphenhydramine can be decreased when it is combined with Lumacaftor.Approved
LumefantrineDiphenhydramine may increase the QTc-prolonging activities of Lumefantrine.Approved
LurasidoneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Lurasidone.Approved
Magnesium SulfateMagnesium Sulfate may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine.Approved, Vet Approved
MaprotilineThe metabolism of Maprotiline can be decreased when combined with Diphenhydramine.Approved
MeclizineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Meclizine.Approved
MedetomidineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Medetomidine.Vet Approved
MelatoninThe risk or severity of adverse effects can be increased when Melatonin is combined with Diphenhydramine.Approved, Nutraceutical, Vet Approved
MelperoneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Melperone.Approved
MephedroneMephedrone may decrease the sedative activities of Diphenhydramine.Investigational
MephentermineMephentermine may decrease the sedative activities of Diphenhydramine.Approved
MephenytoinThe metabolism of Mephenytoin can be decreased when combined with Diphenhydramine.Investigational, Withdrawn
MepivacaineThe risk or severity of adverse effects can be increased when Mepivacaine is combined with Diphenhydramine.Approved, Vet Approved
MeprobamateThe risk or severity of adverse effects can be increased when Meprobamate is combined with Diphenhydramine.Approved, Illicit
MequitazineThe metabolism of Mequitazine can be decreased when combined with Diphenhydramine.Approved
MesoridazineThe metabolism of Mesoridazine can be decreased when combined with Diphenhydramine.Approved
MetaxaloneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Metaxalone.Approved
MethadoneDiphenhydramine may increase the QTc-prolonging activities of Methadone.Approved
Methadyl AcetateThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Methadyl Acetate.Approved, Illicit
MethamphetamineThe metabolism of Methamphetamine can be decreased when combined with Diphenhydramine.Approved, Illicit
MethapyrileneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Methapyrilene.Withdrawn
MethaqualoneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Methaqualone.Illicit, Withdrawn
MethocarbamolThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Methocarbamol.Approved, Vet Approved
MethohexitalThe risk or severity of adverse effects can be increased when Methohexital is combined with Diphenhydramine.Approved
MethotrimeprazineDiphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.Approved
MethoxyfluraneThe metabolism of Methoxyflurane can be decreased when combined with Diphenhydramine.Approved, Vet Approved
MethsuximideThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Methsuximide.Approved
MethylecgonineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with ECGONINE METHYL ESTER.Experimental
MethylphenidateThe metabolism of Methylphenidate can be decreased when combined with Diphenhydramine.Approved, Investigational
MethylphenobarbitalThe risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Diphenhydramine.Approved
MethyprylonThe metabolism of Methyprylon can be decreased when combined with Diphenhydramine.Approved, Illicit, Withdrawn
MetoclopramideThe metabolism of Metoclopramide can be decreased when combined with Diphenhydramine.Approved, Investigational
MetoprololThe serum concentration of Metoprolol can be increased when it is combined with Diphenhydramine.Approved, Investigational
MetyrosineDiphenhydramine may increase the sedative activities of Metyrosine.Approved
MexiletineThe metabolism of Diphenhydramine can be decreased when combined with Mexiletine.Approved
MianserinThe metabolism of Mianserin can be decreased when combined with Diphenhydramine.Approved
MidazolamThe risk or severity of adverse effects can be increased when Midazolam is combined with Diphenhydramine.Approved, Illicit
MifepristoneThe serum concentration of Diphenhydramine can be increased when it is combined with Mifepristone.Approved, Investigational
MilnacipranThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Milnacipran.Approved
MinaprineThe metabolism of Minaprine can be decreased when combined with Diphenhydramine.Approved
MinocyclineMinocycline may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine.Approved, Investigational
MirabegronThe metabolism of Mirabegron can be decreased when combined with Diphenhydramine.Approved
MirtazapineDiphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.Approved
MMDAMMDA may decrease the sedative activities of Diphenhydramine.Experimental, Illicit
MoclobemideThe metabolism of Moclobemide can be decreased when combined with Diphenhydramine.Approved
ModafinilThe metabolism of Diphenhydramine can be decreased when combined with Modafinil.Approved, Investigational
MolindoneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Molindone.Approved
MorphineThe metabolism of Morphine can be decreased when combined with Diphenhydramine.Approved, Investigational
MoxifloxacinDiphenhydramine may increase the QTc-prolonging activities of Moxifloxacin.Approved, Investigational
NabiloneNabilone may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine.Approved, Investigational
NalbuphineThe risk or severity of adverse effects can be increased when Nalbuphine is combined with Diphenhydramine.Approved
NateglinideThe metabolism of Nateglinide can be decreased when combined with Diphenhydramine.Approved, Investigational
NebivololThe serum concentration of Nebivolol can be increased when it is combined with Diphenhydramine.Approved, Investigational
NefazodoneThe metabolism of Nefazodone can be decreased when combined with Diphenhydramine.Approved, Withdrawn
NelfinavirThe metabolism of Diphenhydramine can be decreased when combined with Nelfinavir.Approved
NetupitantThe metabolism of Netupitant can be decreased when combined with Diphenhydramine.Approved
NevirapineThe metabolism of Diphenhydramine can be increased when combined with Nevirapine.Approved
NicardipineThe metabolism of Diphenhydramine can be decreased when combined with Nicardipine.Approved
NicergolineThe metabolism of Nicergoline can be decreased when combined with Diphenhydramine.Approved
NicotineThe metabolism of Nicotine can be decreased when combined with Diphenhydramine.Approved
NifedipineThe metabolism of Nifedipine can be decreased when combined with Diphenhydramine.Approved
NilotinibDiphenhydramine may increase the QTc-prolonging activities of Nilotinib.Approved, Investigational
NitrazepamThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Nitrazepam.Approved
NitrofuralThe metabolism of Nitrofural can be decreased when combined with Diphenhydramine.Approved, Vet Approved
Nitrous oxideThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Nitrous oxide.Approved, Vet Approved
NorfluraneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with 1,1,1,2 Tetrafluoroethane.Investigational
NormethadoneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Normethadone.Approved, Illicit
NortriptylineThe metabolism of Nortriptyline can be decreased when combined with Diphenhydramine.Approved
OfloxacinDiphenhydramine may increase the QTc-prolonging activities of Ofloxacin.Approved
OlanzapineThe metabolism of Olanzapine can be decreased when combined with Diphenhydramine.Approved, Investigational
OlopatadineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Olopatadine.Approved
OmeprazoleThe metabolism of Diphenhydramine can be decreased when combined with Omeprazole.Approved, Investigational, Vet Approved
OndansetronDiphenhydramine may increase the QTc-prolonging activities of Ondansetron.Approved
OpiumThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Opium.Approved, Illicit
OrphenadrineDiphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.Approved
OsanetantThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Osanetant.Investigational
OsimertinibThe serum concentration of Diphenhydramine can be decreased when it is combined with Osimertinib.Approved
OxazepamThe risk or severity of adverse effects can be increased when Oxazepam is combined with Diphenhydramine.Approved
OxethazaineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Oxetacaine.Investigational
OxprenololThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Oxprenolol.Approved
OxybuprocaineThe risk or severity of adverse effects can be increased when Oxybuprocaine is combined with Diphenhydramine.Approved
OxycodoneThe metabolism of Oxycodone can be decreased when combined with Diphenhydramine.Approved, Illicit, Investigational
OxymorphoneThe metabolism of Oxymorphone can be decreased when combined with Diphenhydramine.Approved, Investigational, Vet Approved
PaliperidoneDiphenhydramine may increase the QTc-prolonging activities of Paliperidone.Approved
PalonosetronThe metabolism of Palonosetron can be decreased when combined with Diphenhydramine.Approved, Investigational
PanobinostatThe serum concentration of Diphenhydramine can be increased when it is combined with Panobinostat.Approved, Investigational
PantoprazoleThe metabolism of Diphenhydramine can be decreased when combined with Pantoprazole.Approved
ParaldehydeDiphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.Approved
ParoxetineThe metabolism of Diphenhydramine can be decreased when combined with Paroxetine.Approved, Investigational
PazopanibDiphenhydramine may increase the QTc-prolonging activities of Pazopanib.Approved
Peginterferon alfa-2bThe serum concentration of Diphenhydramine can be decreased when it is combined with Peginterferon alfa-2b.Approved
PentamidineDiphenhydramine may increase the QTc-prolonging activities of Pentamidine.Approved
PentazocineThe risk or severity of adverse effects can be increased when Pentazocine is combined with Diphenhydramine.Approved, Vet Approved
PentobarbitalThe risk or severity of adverse effects can be increased when Pentobarbital is combined with Diphenhydramine.Approved, Vet Approved
PerampanelPerampanel may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine.Approved
PerazineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Perazine.Investigational
PerflutrenDiphenhydramine may increase the QTc-prolonging activities of Perflutren.Approved
PerhexilineThe metabolism of Perhexiline can be decreased when combined with Diphenhydramine.Approved
PerospironeThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Perospirone.Approved
PerphenazineThe metabolism of Perphenazine can be decreased when combined with Diphenhydramine.Approved
PethidineThe metabolism of Pethidine can be decreased when combined with Diphenhydramine.Approved
PhenacetinThe metabolism of Phenacetin can be decreased when combined with Diphenhydramine.Withdrawn
PhenforminThe metabolism of Phenformin can be decreased when combined with Diphenhydramine.Approved, Withdrawn
PhenobarbitalThe metabolism of Diphenhydramine can be increased when combined with Phenobarbital.Approved
PhenoxyethanolThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Phenoxyethanol.Approved
PhenterminePhentermine may decrease the sedative activities of Diphenhydramine.Approved, Illicit
PhenytoinThe metabolism of Diphenhydramine can be increased when combined with Phenytoin.Approved, Vet Approved
PimozideDiphenhydramine may increase the QTc-prolonging activities of Pimozide.Approved
PindololThe metabolism of Pindolol can be decreased when combined with Diphenhydramine.Approved
PipamperoneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Pipamperone.Approved
PiperazineThe metabolism of Piperazine can be decreased when combined with Diphenhydramine.Approved, Vet Approved
PipotiazineThe metabolism of Pipotiazine can be decreased when combined with Diphenhydramine.Approved
PiritramideThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Piritramide.Investigational
PizotifenThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Pizotifen.Approved
PomalidomideThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Pomalidomide.Approved
PonatinibThe metabolism of Ponatinib can be decreased when combined with Diphenhydramine.Approved
PramipexoleDiphenhydramine may increase the sedative activities of Pramipexole.Approved, Investigational
PramocaineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Pramocaine.Approved
PrazepamThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Prazepam.Approved, Illicit
PregabalinThe risk or severity of adverse effects can be increased when Pregabalin is combined with Diphenhydramine.Approved, Illicit, Investigational
PrilocaineThe risk or severity of adverse effects can be increased when Prilocaine is combined with Diphenhydramine.Approved
PrimaquineDiphenhydramine may increase the QTc-prolonging activities of Primaquine.Approved
PrimidoneThe metabolism of Diphenhydramine can be increased when combined with Primidone.Approved, Vet Approved
ProcainamideDiphenhydramine may increase the QTc-prolonging activities of Procainamide.Approved
ProcaineThe risk or severity of adverse effects can be increased when Procaine is combined with Diphenhydramine.Approved, Investigational, Vet Approved
ProchlorperazineThe metabolism of Prochlorperazine can be decreased when combined with Diphenhydramine.Approved, Vet Approved
ProgesteroneThe metabolism of Progesterone can be decreased when combined with Diphenhydramine.Approved, Vet Approved
PromazineDiphenhydramine may increase the QTc-prolonging activities of Promazine.Approved, Vet Approved
PromethazineThe metabolism of Promethazine can be decreased when combined with Diphenhydramine.Approved
PropafenoneThe serum concentration of Diphenhydramine can be increased when it is combined with Propafenone.Approved
ProparacaineThe risk or severity of adverse effects can be increased when Proparacaine is combined with Diphenhydramine.Approved, Vet Approved
PropofolThe metabolism of Propofol can be decreased when combined with Diphenhydramine.Approved, Investigational, Vet Approved
PropoxycaineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Propoxycaine.Approved
PropranololThe metabolism of Propranolol can be decreased when combined with Diphenhydramine.Approved, Investigational
ProtriptylineThe metabolism of Protriptyline can be decreased when combined with Diphenhydramine.Approved
PSD502The risk or severity of adverse effects can be increased when Diphenhydramine is combined with PSD502.Investigational
PseudoephedrineThe metabolism of Pseudoephedrine can be decreased when combined with Diphenhydramine.Approved
PyrimethamineThe metabolism of Diphenhydramine can be decreased when combined with Pyrimethamine.Approved, Vet Approved
QuazepamThe serum concentration of Diphenhydramine can be increased when it is combined with Quazepam.Approved, Illicit
QuetiapineDiphenhydramine may increase the QTc-prolonging activities of Quetiapine.Approved
QuinidineDiphenhydramine may increase the QTc-prolonging activities of Quinidine.Approved
QuinineDiphenhydramine may increase the QTc-prolonging activities of Quinine.Approved
RacloprideThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Raclopride.Investigational
RamelteonThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Ramelteon.Approved, Investigational
RanitidineThe metabolism of Ranitidine can be decreased when combined with Diphenhydramine.Approved
RanolazineThe metabolism of Diphenhydramine can be decreased when combined with Ranolazine.Approved, Investigational
RemifentanilThe risk or severity of adverse effects can be increased when Remifentanil is combined with Diphenhydramine.Approved
RemoxiprideThe metabolism of Remoxipride can be decreased when combined with Diphenhydramine.Approved, Withdrawn
repinotanThe metabolism of repinotan can be decreased when combined with Diphenhydramine.Investigational
ReserpineThe risk or severity of adverse effects can be increased when Reserpine is combined with Diphenhydramine.Approved
RifampicinThe metabolism of Diphenhydramine can be increased when combined with Rifampicin.Approved
RifapentineThe metabolism of Diphenhydramine can be increased when combined with Rifapentine.Approved
RisperidoneThe metabolism of Risperidone can be decreased when combined with Diphenhydramine.Approved, Investigational
RitanserinThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Ritanserin.Investigational
RitobegronRitobegron may decrease the sedative activities of Diphenhydramine.Investigational
RitonavirThe metabolism of Diphenhydramine can be decreased when combined with Ritonavir.Approved, Investigational
RolapitantThe metabolism of Diphenhydramine can be decreased when combined with Rolapitant.Approved
RomifidineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Romifidine.Vet Approved
RopiniroleDiphenhydramine may increase the sedative activities of Ropinirole.Approved, Investigational
RopivacaineThe metabolism of Ropivacaine can be decreased when combined with Diphenhydramine.Approved
RotigotineDiphenhydramine may increase the sedative activities of Rotigotine.Approved
RufinamideThe risk or severity of adverse effects can be increased when Rufinamide is combined with Diphenhydramine.Approved
SaquinavirDiphenhydramine may increase the QTc-prolonging activities of Saquinavir.Approved, Investigational
ScopolamineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Scopolamine.Approved
SecobarbitalThe metabolism of Diphenhydramine can be increased when combined with Secobarbital.Approved, Vet Approved
SepranoloneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Uc1010.Investigational
SertindoleThe metabolism of Sertindole can be decreased when combined with Diphenhydramine.Approved, Withdrawn
SertralineThe metabolism of Sertraline can be decreased when combined with Diphenhydramine.Approved
SevofluraneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Sevoflurane.Approved, Vet Approved
SildenafilThe metabolism of Sildenafil can be decreased when combined with Diphenhydramine.Approved, Investigational
SimeprevirThe metabolism of Diphenhydramine can be decreased when combined with Simeprevir.Approved
SimvastatinThe metabolism of Simvastatin can be decreased when combined with Diphenhydramine.Approved
Sodium oxybateSodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine.Approved
SorafenibThe metabolism of Diphenhydramine can be decreased when combined with Sorafenib.Approved, Investigational
SotalolDiphenhydramine may increase the QTc-prolonging activities of Sotalol.Approved
SparteineThe metabolism of Sparteine can be decreased when combined with Diphenhydramine.Experimental
StiripentolThe metabolism of Diphenhydramine can be decreased when combined with Stiripentol.Approved
SufentanilThe risk or severity of adverse effects can be increased when Sufentanil is combined with Diphenhydramine.Approved, Investigational
SulfadiazineThe metabolism of Diphenhydramine can be decreased when combined with Sulfadiazine.Approved, Vet Approved
SulfamethoxazoleThe metabolism of Diphenhydramine can be decreased when combined with Sulfamethoxazole.Approved
SulfisoxazoleThe metabolism of Diphenhydramine can be decreased when combined with Sulfisoxazole.Approved, Vet Approved
SulpirideThe risk or severity of adverse effects can be increased when Sulpiride is combined with Diphenhydramine.Approved
SuvorexantDiphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.Approved
TamoxifenThe serum concentration of the active metabolites of Tamoxifen can be reduced when Tamoxifen is used in combination with Diphenhydramine resulting in a loss in efficacy.Approved
TamsulosinThe metabolism of Tamsulosin can be decreased when combined with Diphenhydramine.Approved, Investigational
TandospironeThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Tandospirone.Investigational
TapentadolTapentadol may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine.Approved
TasimelteonThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Tasimelteon.Approved
Technetium Tc-99m tilmanoceptDiphenhydramine may decrease effectiveness of Technetium Tc-99m tilmanocept as a diagnostic agent.Approved
TegaserodThe metabolism of Tegaserod can be decreased when combined with Diphenhydramine.Investigational, Withdrawn
TelavancinDiphenhydramine may increase the QTc-prolonging activities of Telavancin.Approved
TelithromycinDiphenhydramine may increase the QTc-prolonging activities of Telithromycin.Approved
TemazepamThe risk or severity of adverse effects can be increased when Temazepam is combined with Diphenhydramine.Approved
Tenofovir disoproxilThe metabolism of Diphenhydramine can be decreased when combined with Tenofovir.Approved, Investigational
TerbinafineThe metabolism of Diphenhydramine can be decreased when combined with Terbinafine.Approved, Investigational, Vet Approved
TerfenadineThe metabolism of Terfenadine can be decreased when combined with Diphenhydramine.Withdrawn
TeriflunomideThe serum concentration of Diphenhydramine can be decreased when it is combined with Teriflunomide.Approved
TesmilifeneThe metabolism of Tesmilifene can be decreased when combined with Diphenhydramine.Investigational
TetrabenazineDiphenhydramine may increase the QTc-prolonging activities of Tetrabenazine.Approved
TetracaineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Tetracaine.Approved, Vet Approved
TetrodotoxinThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Tetrodotoxin.Investigational
ThalidomideDiphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.Approved, Investigational, Withdrawn
TheophyllineThe metabolism of Diphenhydramine can be decreased when combined with Theophylline.Approved
ThiamylalThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Thiamylal.Approved, Vet Approved
ThiopentalThe risk or severity of adverse effects can be increased when Thiopental is combined with Diphenhydramine.Approved, Vet Approved
ThioridazineThe serum concentration of Thioridazine can be increased when it is combined with Diphenhydramine.Withdrawn
ThiotepaThe metabolism of Diphenhydramine can be decreased when combined with Thiotepa.Approved
ThiothixeneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Thiothixene.Approved
TiagabineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Tiagabine.Approved
TiaprideThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Tiapride.Approved, Investigational
TicagrelorThe metabolism of Diphenhydramine can be decreased when combined with Ticagrelor.Approved
TiclopidineThe metabolism of Diphenhydramine can be decreased when combined with Ticlopidine.Approved
TiletamineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Tiletamine.Vet Approved
TimololThe metabolism of Timolol can be decreased when combined with Diphenhydramine.Approved
TiotropiumThe metabolism of Tiotropium can be decreased when combined with Diphenhydramine.Approved
TipranavirThe metabolism of Diphenhydramine can be decreased when combined with Tipranavir.Approved, Investigational
TizanidineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Tizanidine.Approved
TolbutamideThe metabolism of Diphenhydramine can be decreased when combined with Tolbutamide.Approved
TolcaponeThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Tolcapone.Approved, Withdrawn
TolterodineThe metabolism of Tolterodine can be decreased when combined with Diphenhydramine.Approved, Investigational
TopiramateThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Topiramate.Approved
ToremifeneDiphenhydramine may increase the QTc-prolonging activities of Toremifene.Approved, Investigational
TrabectedinThe metabolism of Trabectedin can be decreased when combined with Diphenhydramine.Approved, Investigational
TramadolThe therapeutic efficacy of Tramadol can be decreased when used in combination with Diphenhydramine.Approved, Investigational
Trans-2-PhenylcyclopropylamineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Trans-2-Phenylcyclopropylamine.Experimental
TranylcypromineThe metabolism of Diphenhydramine can be decreased when combined with Tranylcypromine.Approved
TrazodoneThe metabolism of Trazodone can be decreased when combined with Diphenhydramine.Approved, Investigational
TriazolamThe risk or severity of adverse effects can be increased when Triazolam is combined with Diphenhydramine.Approved
TrifluoperazineThe risk or severity of adverse effects can be increased when Trifluoperazine is combined with Diphenhydramine.Approved
TriflupromazineThe risk or severity of adverse effects can be increased when Triflupromazine is combined with Diphenhydramine.Approved, Vet Approved
TrimethoprimThe metabolism of Diphenhydramine can be decreased when combined with Trimethoprim.Approved, Vet Approved
TrimipramineThe metabolism of Trimipramine can be decreased when combined with Diphenhydramine.Approved
TriprolidineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Triprolidine.Approved
UmeclidiniumThe metabolism of Umeclidinium can be decreased when combined with Diphenhydramine.Approved
Valproic AcidThe risk or severity of adverse effects can be increased when Valproic Acid is combined with Diphenhydramine.Approved, Investigational
ValsartanThe metabolism of Diphenhydramine can be decreased when combined with Valsartan.Approved, Investigational
VandetanibDiphenhydramine may increase the QTc-prolonging activities of Vandetanib.Approved
VemurafenibThe serum concentration of Diphenhydramine can be increased when it is combined with Vemurafenib.Approved
VenlafaxineThe metabolism of Diphenhydramine can be decreased when combined with Venlafaxine.Approved
VigabatrinThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Vigabatrin.Approved
VilazodoneThe metabolism of Vilazodone can be decreased when combined with Diphenhydramine.Approved
VinblastineThe metabolism of Vinblastine can be decreased when combined with Diphenhydramine.Approved
VinorelbineThe metabolism of Vinorelbine can be decreased when combined with Diphenhydramine.Approved, Investigational
VoriconazoleThe metabolism of Diphenhydramine can be decreased when combined with Voriconazole.Approved, Investigational
VortioxetineThe metabolism of Vortioxetine can be decreased when combined with Diphenhydramine.Approved
XylazineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Xylazine.Vet Approved
YohimbineThe metabolism of Yohimbine can be decreased when combined with Diphenhydramine.Approved, Vet Approved
ZafirlukastThe metabolism of Diphenhydramine can be decreased when combined with Zafirlukast.Approved, Investigational
ZalcitabineThe metabolism of Zalcitabine can be decreased when combined with Diphenhydramine.Approved
ZaleplonThe risk or severity of adverse effects can be increased when Zaleplon is combined with Diphenhydramine.Approved, Illicit, Investigational
ZiconotideThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Ziconotide.Approved
ZimelidineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Zimelidine.Withdrawn
ZiprasidoneDiphenhydramine may increase the QTc-prolonging activities of Ziprasidone.Approved
ZolazepamThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Zolazepam.Vet Approved
ZolpidemDiphenhydramine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.Approved
ZonisamideThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Zonisamide.Approved, Investigational
ZopicloneThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Zopiclone.Approved
ZotepineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Zotepine.Approved
ZuclopenthixolDiphenhydramine may increase the QTc-prolonging activities of Zuclopenthixol.Approved, Investigational
Food Interactions
  • Avoid alcohol.
  • Take with food.
References
Synthesis Reference

Alison B. Lukacsko, Joseph J. Piala, "Effect of a combination of a terbutaline, diphenhydramine and ranitidine composition on gastrointestinal injury produced by nonsteroidal anti-inflammatory compositions." U.S. Patent US5260333, issued December, 1983.

US5260333
General References
  1. Raphael GD, Angello JT, Wu MM, Druce HM: Efficacy of diphenhydramine vs desloratadine and placebo in patients with moderate-to-severe seasonal allergic rhinitis. Ann Allergy Asthma Immunol. 2006 Apr;96(4):606-14. [PubMed:16680933 ]
  2. Abdi A, Rose E, Levine M: Diphenhydramine overdose with intraventricular conduction delay treated with hypertonic sodium bicarbonate and i.v. lipid emulsion. West J Emerg Med. 2014 Nov;15(7):855-8. doi: 10.5811/westjem.2014.8.23407. Epub 2014 Sep 19. [PubMed:25493135 ]
External Links
ATC CodesD04AA32 — DiphenhydramineD04AA33 — Diphenhydramine methylbromideR06AA02 — DiphenhydramineR06AA52 — Diphenhydramine, combinations
AHFS Codes
  • 04:04.04
PDB EntriesNot Available
FDA labelNot Available
MSDSDownload (73.5 KB)
Clinical Trials
Clinical Trials
PhaseStatusPurposeConditionsCount
0Not Yet RecruitingTreatmentPost-Traumatic Headaches1
1CompletedNot AvailableAutonomic Failure / Idiopathic orthostatic hypotension1
1CompletedNot AvailableHealthy Volunteers2
1CompletedNot AvailableTherapeutic Equivalence1
1CompletedBasic ScienceAllergic Rhinitis (AR)1
1CompletedBasic ScienceNasal Stuffiness1
1CompletedTreatmentHealthy Volunteers3
1CompletedTreatmentMajor Depressive Disorder (MDD)1
1CompletedTreatmentRestless Legs Syndrome (RLS)1
1RecruitingDiagnosticPatients With Suspected Malignancies of the Pituitary Gland1
1RecruitingDiagnosticA Diagnosis of Any Resectable Lung or Pleural Nodule1
1RecruitingScreeningFibrosis1
1RecruitingTreatmentGraft Versus Host Disease (GVHD) / Sickle Cell Disorders1
1RecruitingTreatmentMultiple Myeloma (MM)1
1RecruitingTreatmentPompe's Disease1
1RecruitingTreatmentTransplantation, Liver1
1RecruitingTreatmentTumors, Solid1
1TerminatedNot AvailableHealthy Male Volunteers1
1TerminatedBasic ScienceDrug Metabolism, Poor, CYP2D6-RELATED1
1WithdrawnDiagnosticAbdominal Pain (AP) / Gallbladder disorders / Gallstone formation / Jaundice / Pancreatitis1
1, 2CompletedTreatmentKidney Diseases / Transplantation, Kidney1
1, 2CompletedTreatmentLeukemia, Acute Lymphocytic (ALL) / Leukemia, Acute Myelogenous (AML) / Leukemia, Chronic Myelogenous (CML) / Myelodysplastic Syndromes (MDS) / Non-Hodgkin's Lymphoma (NHL)1
1, 2RecruitingTreatmentAdult Living Donor Kidney Transplant Recipients / Living Kidney Donors / Transplant, Kidney1
1, 2RecruitingTreatmentLiver Transplant Recipients / Living Donor (of the Respective Liver Transplant Recipient)1
1, 2RecruitingTreatmentLung Cancers1
2Active Not RecruitingTreatmentAdvanced Stage Diffuse Large B-Cell Non-Hodgkin's Lymphoma / Non-Hodgkin's Lymphoma (NHL)1
2Active Not RecruitingTreatmentMultiple Myeloma (MM)1
2Active Not RecruitingTreatmentNephritis, Lupus1
2Active Not RecruitingTreatmentRenal Cancers1
2CompletedNot AvailableCancers / Tumors, Solid1
2CompletedSupportive CareStomatitis, Aphthous1
2CompletedTreatmentAcute Cerebrovascular Accidents / Edema of the cerebrum1
2CompletedTreatmentBlood Cancers / CLL / Graft Versus Host Disease (GVHD) / Hodgkins Disease (HD) / Leukemias / Malignancies / NHL / Smith-Magenis Syndrome1
2CompletedTreatmentCancer, Breast1
2CompletedTreatmentChronic Idiopathic Urticaria1
2CompletedTreatmentDepressive State1
2CompletedTreatmentEndometrial Cancers1
2CompletedTreatmentLupus Erythematosus, Systemic1
2CompletedTreatmentMalignant Lymphomas1
2CompletedTreatmentRejection, Transplant1
2CompletedTreatmentRenal Cell Adenocarcinoma1
2CompletedTreatmentRestless Legs Syndrome (RLS)1
2CompletedTreatmentVulvodynia1
2RecruitingTreatmentAlcohol Dependence1
2RecruitingTreatmentCocaine-Related Disorders1
2RecruitingTreatmentPlasma Cell Myeloma2
2RecruitingTreatmentT-cell Type Acute Leukemia-Precursor T-lymphoblastic Lymphoma/Leukaemia1
2RecruitingTreatmentTransplant, Kidney1
2TerminatedSupportive CareNausea / Unspecified Childhood Solid Tumor, Protocol Specific / Vomiting1
2TerminatedTreatmentProstate Cancer1
2TerminatedTreatmentTransplantation, Kidney1
2, 3CompletedTreatmentLupus Erythematosus, Systemic1
2, 3CompletedTreatmentVesicular Stomatitis1
2, 3RecruitingTreatmentMalaria caused by Plasmodium falciparum1
2, 3TerminatedTreatmentLupus Erythematosus, Systemic1
3CompletedTreatmentAcute Urticaria1
3CompletedTreatmentChronic Idiopathic Urticaria1
3CompletedTreatmentElective Caesarean Section Surgeries1
3CompletedTreatmentHealthy Volunteers1
3CompletedTreatmentMigraines1
3CompletedTreatmentNephritis, Lupus1
3Not Yet RecruitingTreatmentAcute Urticaria1
3RecruitingTreatmentAnxiety Disorder / Dementias / Depressive State / Psychosomatic Disorders / Schizophrenic Disorders1
3RecruitingTreatmentHeadaches / Intranasal Ketamine1
3RecruitingTreatmentPost-Traumatic Headaches1
3Unknown StatusTreatmentSleeplessness1
3WithdrawnTreatmentCoughing / Inflammatory Reaction / Rhinitis1
4Active Not RecruitingSupportive CareAdjunct Anesthesia Medication / Colonoscopy1
4CompletedDiagnosticAsthma Bronchial1
4CompletedPreventionHypnotic / Specified Sedative1
4CompletedTreatmentCough Reflex Sensitivity1
4CompletedTreatmentHeadaches1
4CompletedTreatmentInfections, Bacterial1
4CompletedTreatmentMigraines2
4CompletedTreatmentMigrainous Headache / Nausea / Restlessness1
4CompletedTreatmentNasal Stuffiness1
4CompletedTreatmentExtra-pyramidal symptoms / Nausea1
4CompletedTreatmentNeurogenic Intermittent Claudication / Spinal Stenosis of Lumbar Region1
4CompletedTreatmentOccasional Sleeplessness1
4RecruitingTreatmentMigraines1
4SuspendedTreatmentMigrainous Headache1
Not AvailableActive Not RecruitingScreeningAlcoholism1
Not AvailableCompletedNot AvailablePain, Neuropathic1
Not AvailableCompletedBasic ScienceHyperalgesia1
Not AvailableCompletedBasic ScienceMemory, Long-Term / Memory, Short-Term1
Not AvailableCompletedPreventionGeneral Surgery / Pain1
Not AvailableCompletedPreventionHeadaches1
Not AvailableCompletedSupportive CareFocus of Study: Absorption of the Three Components in the Topical ABH Gel in Healthy Volunteers, and Determine if There Are Any Adverse Effects / Healthy Volunteers1
Not AvailableCompletedSupportive CareNausea / Vomiting1
Not AvailableCompletedTreatmentBenign Paroxysmal Positional Vertigo (BPPV)1
Not AvailableCompletedTreatmentEndometriosis1
Not AvailableCompletedTreatmentEndoscopy / Sedation therapy1
Not AvailableCompletedTreatmentItching1
Not AvailableCompletedTreatmentPain1
Not AvailableEnrolling by InvitationTreatmentMigrainous Headache1
Not AvailableRecruitingTreatmentAlcohol-Related Disorders / Brain Injury / Chronic Diseases / Depressive State / Mild Cognitive Impairment (MCI) / Pain / Posttraumatic Stress Disorders / Quality of Life / Substance-Related Disorders / Suicidal Ideation / Wounds and Injuries1
Not AvailableRecruitingTreatmentAnxiety Disorder / Moods Disorders / Pain Disorders / Somatization Disorder1
Not AvailableSuspendedDiagnosticBulimia Nervosa (BN) / Catechol-O-methyltransferase / Dopamine / Eating Disorders / Reward1
Not AvailableTerminatedTreatmentHuman Immunodeficiency Virus (HIV) Infections1
Not AvailableTerminatedTreatmentPrimary Headaches (Includes Migraines, Tension, Cluster Headaches)1
Not AvailableUnknown StatusSupportive CareEndoscopic Retrograde Cholangiopancreatography (ERCP) / Endoscopic Ultrasound (EUS)1
Not AvailableUnknown StatusTreatmentPost Operative Nausea and Vomiting (PONV) / Rescue Emetic Therapy1
Pharmacoeconomics
ManufacturersNot Available
Packagers
Dosage forms
FormRouteStrength
LiquidOral50 mg/30mL
Capsule; kitOral
CreamTopical20 mg/mL
CreamTopical2 mL/100mL
PowderOral
PowderOral25 mg/1
LiquidOral12.5 mg
Tablet, chewableOral12.5 mg/1
Tablet, film coatedOral25 mg/1
SolutionOral12.5 mg
GelTopical2 g/100g
CreamTopical2.0 %
SprayTopical
PatchTopical
Kit
TabletOral25 mg
Tablet, coatedOral25 mg/1
Tablet, chewableOral12.5 mg
LiquidTopical
LiquidOral6.25 mg
CreamTopical2 %
ElixirOral12.5 mg
GelTopical20 mg/mL
Tablet, chewableOral25 mg
GelTopical2 %
TabletOral25 mg/250mg
StripOral25 mg
LotionTopical
TabletOral19 mg
StripOral19 mg
SuspensionOral
TabletOral12.5 mg/1
LiquidOral
LiquidOral12.5 mg/5mL
OintmentTopical
KitTopical
KitOral
TabletOral38.0 mg
CapsuleOral25 mg/1
Capsule, coatedOral25 mg/1
Injection, solutionIntravenous50 mg/mL
Capsule, liquid filledOral20 mg/1
TabletOral50 mg/1
Capsule, gelatin coatedOral25 mg/1
SyrupOral6.25 mg
LiquidIntravenous50 mg
ElixirOral12.5 mg/5mL
ElixirOral25 mg/10mL
InjectionIntramuscular50 mg/mL
InjectionIntramuscular; Intravenous50 mg/mL
Injection, solutionIntramuscular; Intravenous50 mg/mL
SolutionOral25 mg/10mL
SolutionOral50 mg/20mL
KitOral; Topical
TabletOral
Tablet, film coatedOral
SolutionOral50 mg/40mL
KitOral
Aerosol, sprayTopical
SolutionOral12.5 mg/5mL
Tablet, coatedOral
TabletOral25 mg/1
Capsule, coatedOral
Capsule, liquid filledOral25 mg/1
SolutionOral50 mg/30mL
Capsule, liquid filledOral
LiquidTopical20.3 g/L
SprayTopical2 g/100mL
AerosolTopical
SolutionTopical
GelTopical2 g/100mL
StripOral12.5 mg
TabletOral12.5 mg
Tablet, orally disintegratingOral12.5 mg/1
LinimentTopical
LozengeOral25 mg
StripOral
CapsuleOral25 mg
SolutionOral50 mg
CapsuleOral50 mg/1
Tablet, film coatedOral50 mg/1
Capsule, liquid filledOral50 mg/21
TabletOral50 mg
Capsule, gelatin coatedOral
ElixirOral2.5 mg
LiquidIntramuscular; Intravenous50 mg
SyrupOral12.5 mg/5mL
GelTopical20.5 mg/mL
SolutionOral
PlasterTopical
SolutionIntramuscular; Intravenous50 mg
GelTopical.2 g/10mL
Capsule, liquid filledOral50 mg/1
Tablet, coatedOral50 mg/1
GelTopical
GelTopical20 mg/g
SprayTopical20 mg/mL
Powder, for solutionOral
SyrupOral
Kit; tabletOral
Kit
CapsuleOral50 mg
Tablet, chewableOral25 mg/1
LiquidOral6.25 mg/mL
CreamTopical
LiquidOral25 mg/10mL
CapsuleOral
Capsule, gelatin coatedOral50 mg/21
Granule, for solutionOral
SprayTopical2.0 %
LiquidOral50 mg
Prices
Unit descriptionCostUnit
DiphenhydrAMINE HCl 100 50 mg capsule Bottle13.99USD bottle
Diphenhydramine 50 mg/ml3.94USD ml
Diphenhydramine 50 mg/ml vial1.69USD ml
DiphenhydrAMINE HCl 50 mg/ml vial1.44USD vial
Dytan 25 mg tablet chewable1.37USD tablet
Benadryl 50 mg/ml vial1.36USD ml
Diphenmax 25 mg tablet1.24USD tablet
Benadryl allergy 25 mg strips0.45USD strip
Unisom sleep aid tablet0.34USD tablet
Sleep-eze 3 tablet0.29USD tablet
Compoz 50 mg tablet0.27USD tablet
Sominex max str 50 mg caplet0.27USD caplet
Benadryl allergy fastmelt tablet0.26USD tablet
Unisom 25 mg sleeptabs0.25USD tablet
Unisom 50 mg sleepgels0.25USD each
Unisom sleepmelts 25 mg tablet0.24USD tablet
Nytol 25 mg tablet0.23USD tablet
Benadryl allergy-sinus caplet0.22USD caplet
Compoz 25 mg gelcap0.2USD capsule
Benadryl allergy 25 mg softgel0.19USD softgel capsule
Benadryl allergy 25 mg ultratab0.19USD tablet
Benadryl allergy-cold kapgels0.19USD each
Benadryl allergy-sinus kapgels0.19USD each
Benadryl-d allergy-sinus ultratab0.19USD tablet
Diphenhydramine hcl powder0.17USD g
Eql allergy 25 mg tablet0.17USD tablet
Nighttime sleep aid 25 mg cplt0.17USD caplet
Banophen anti-itch 2% cream0.16USD g
Benadryl itch relief stick0.16USD ml
Sominex 25 mg tablet0.16USD tablet
Benadryl allergy 25 mg kapgels0.15USD each
Allergy 25 mg tablet0.14USD tablet
Benadryl 25 mg kapseals0.14USD each
Benadryl itch stopping crm0.14USD g
DiphenhydrAMINE HCl 25 mg capsule0.13USD capsule
Diphenhist with zinc cream0.12USD g
Ra allergy 25 mg tablet0.12USD tablet
CVS Pharmacy allergy 25 mg tablet0.11USD tablet
Diphenhydramine 25 mg minitab0.11USD tablet
Simply sleep 25 mg caplet0.11USD caplet
Sleep ii tablet0.11USD tablet
Diphenhydramine 50 mg capsule0.1USD capsule
Benadryl 2% spray0.09USD ml
Diphenhist 50 mg tablet0.09USD tablet
Genahist 25 mg tablet0.09USD tablet
Ra sleep tablet0.09USD tablet
Banophen 25 mg tablet0.08USD tablet
Wal-dryl anti-itch spray0.08USD ml
CVS Pharmacy allergy 25 mg caplet0.07USD caplet
Nighttime sleep aid 25 mg caplet0.07USD caplet
CVS Pharmacy itch relief spray0.06USD ml
Diphen 25 mg capsule0.06USD capsule
Diphenhist 25 mg caplet0.06USD caplet
Benadryl anti-itch 0.45% gel0.05USD g
Diphenhydramine 50 mg caplet0.05USD caplet
Benadryl itch stopping gel0.04USD g
Child benadryl-d aller-sin liquid0.04USD ml
Diphenhydramine 25 mg capsule0.04USD capsule
Vicks 44d cough & head liquid0.03USD ml
Vicks 44e cough & chest liquid0.03USD ml
Banophen allergy liquid0.02USD ml
Diphenhydramine 25 mg tablet0.02USD tablet
Ra anti-tussive dm syrup0.02USD ml
Siladryl 12.5 mg/5 ml liquid0.02USD ml
Silphen cough syrup0.02USD ml
Silphen dm cough syrup0.02USD ml
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US8883849 No2002-01-172022-01-17Us
US9155718 No2002-01-172022-01-17Us
US8263647 No2002-05-302022-05-30Us
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point (°C)161-162Martin, H., Hafliger, F.,Gatzi, K.and Grob, A.; U.S. Patent 2,397,799; April 2,1946; assigned to J.R. Geigy AG, Switzerland. Rieveschl, G. Jr.; U.S. Patent 2,421,714; June 3,1947; assigned to Parke, Davis & Co. Rieveschl, G. Jr.; U.S. Patent 2,427,878; September 23,1947; assigned to Parke, Davis & Company.
boiling point (°C)150-165 °C at 2.00E+00 mm HgPhysProp
water solubility3060 mg/L (at 37 °C)BEILSTEIN
logP3.27HANSCH,C ET AL. (1995)
pKa8.98SANGSTER (1994)
Predicted Properties
PropertyValueSource
Water Solubility0.0752 mg/mLALOGPS
logP3.44ALOGPS
logP3.65ChemAxon
logS-3.5ALOGPS
pKa (Strongest Basic)8.87ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area12.47 Å2ChemAxon
Rotatable Bond Count6ChemAxon
Refractivity79.93 m3·mol-1ChemAxon
Polarizability29.86 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9898
Blood Brain Barrier+0.9381
Caco-2 permeable+0.8744
P-glycoprotein substrateSubstrate0.6211
P-glycoprotein inhibitor INon-inhibitor0.6632
P-glycoprotein inhibitor IINon-inhibitor0.8381
Renal organic cation transporterInhibitor0.7752
CYP450 2C9 substrateNon-substrate0.7897
CYP450 2D6 substrateSubstrate0.8919
CYP450 3A4 substrateSubstrate0.6173
CYP450 1A2 substrateInhibitor0.8306
CYP450 2C9 inhibitorNon-inhibitor0.9144
CYP450 2D6 inhibitorInhibitor0.8932
CYP450 2C19 inhibitorNon-inhibitor0.9039
CYP450 3A4 inhibitorNon-inhibitor0.934
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.7293
Ames testNon AMES toxic0.9132
CarcinogenicityNon-carcinogens0.6495
BiodegradationNot ready biodegradable0.9253
Rat acute toxicity2.7846 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.536
hERG inhibition (predictor II)Inhibitor0.6318
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Spectra
Mass Spec (NIST)Not Available
Spectra
Spectrum TypeDescriptionSplash Key
Predicted GC-MSPredicted GC-MS Spectrum - GC-MSNot Available
GC-MSGC-MS Spectrum - EI-Bsplash10-0a4i-9100000000-7b9eb1f702c76f6b6062View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, N/A (Annotated)splash10-0006-0090000000-a71e531b49571f09ab25View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, N/A (Annotated)splash10-00kk-0980000000-cce91896f34562beeffaView in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, N/A (Annotated)splash10-001i-1900000000-4c29bd5e0eab94596eaaView in MoNA
LC-MS/MSLC-MS/MS Spectrum - EI-B (Unknown) , Positivesplash10-0a4i-9100000000-ab642e8f86de11af896cView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QFT , negativesplash10-000t-0910000000-3576ca5ec77ab87354ecView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QFT , positivesplash10-014i-0900000000-0ccd6de9ca58593fd490View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QFT , positivesplash10-014i-0900000000-3568aae4c27ffe333c0eView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QFT , positivesplash10-014i-0900000000-22e0c745355c836f1535View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QFT , positivesplash10-014i-0900000000-6bb69a66a343440c64f8View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QFT , positivesplash10-014i-0900000000-1b87d83415d22bb17f1bView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QFT , positivesplash10-0gb9-0900000000-50251362d768cd1b1c4fView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QFT , positivesplash10-0gb9-0900000000-9f37a733a05f5b01d313View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QFT , positivesplash10-014i-0900000000-7d73b95ed09ea2d72260View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QFT , positivesplash10-0gb9-2900000000-1666a8ab5a6d81c0bd01View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT , positivesplash10-014i-0900000000-3f31841d858381760f03View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT , positivesplash10-014i-0900000000-de872e048c7e12cef490View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT , positivesplash10-014i-0900000000-de872e048c7e12cef490View in MoNA
LC-MS/MSLC-MS/MS Spectrum - , positivesplash10-014i-0900000000-789a4a3fe118d5bf2456View in MoNA
LC-MS/MSLC-MS/MS Spectrum - , positivesplash10-014i-2900000000-8ef94659f614b9ff24caView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, NegativeNot Available
MSMass Spectrum (Electron Ionization)splash10-0a4i-9200000000-b9014c8fc8ccbba24163View in MoNA
1D NMR1H NMR SpectrumNot Available
2D NMR[1H,13C] 2D NMR SpectrumNot Available
Taxonomy
DescriptionThis compound belongs to the class of chemical entities known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.
KingdomChemical entities
Super ClassOrganic compounds
ClassBenzenoids
Sub ClassBenzene and substituted derivatives
Direct ParentDiphenylmethanes
Alternative ParentsBenzylethers / Trialkylamines / Dialkyl ethers / Organopnictogen compounds / Hydrocarbon derivatives
SubstituentsDiphenylmethane / Benzylether / Tertiary aliphatic amine / Tertiary amine / Ether / Dialkyl ether / Organic nitrogen compound / Organic oxygen compound / Organopnictogen compound / Hydrocarbon derivative
Molecular FrameworkAromatic homomonocyclic compounds
External Descriptorstertiary amino compound, ether (CHEBI:4636 ) / a small molecule (CPD-10890 )

Targets

Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
antagonist
General Function:
Histamine receptor activity
Specific Function:
In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
Gene Name:
HRH1
Uniprot ID:
P35367
Uniprot Name:
Histamine H1 receptor
Molecular Weight:
55783.61 Da
References
  1. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
  2. Piao H, Nagai S, Tsurumaki T, Niki T, Higuchi H: Potentiation by neuropeptide Y of histamine H1 receptor-mediated contraction in rat blood vessels. Vascul Pharmacol. 2007 Apr;46(4):260-70. Epub 2006 Oct 27. [PubMed:17169617 ]
  3. Kesiova M, Alexandrova A, Yordanova N, Kirkova M, Todorov S: Effects of diphenhydramine and famotidine on lipid peroxidation and activities of antioxidant enzymes in different rat tissues. Pharmacol Rep. 2006 Mar-Apr;58(2):221-8. [PubMed:16702624 ]
  4. Hasala H, Moilanen E, Janka-Junttila M, Giembycz MA, Kankaanranta H: First-generation antihistamines diphenhydramine and chlorpheniramine reverse cytokine-afforded eosinophil survival by enhancing apoptosis. Allergy Asthma Proc. 2007 Jan-Feb;28(1):79-86. [PubMed:17390763 ]
  5. Wang Z, Woolverton WL: Self-administration of cocaine-antihistamine combinations: super-additive reinforcing effects. Eur J Pharmacol. 2007 Feb 28;557(2-3):159-60. Epub 2006 Dec 1. [PubMed:17196194 ]
  6. Ishikawa T, Takechi K, Rahman A, Ago J, Matsumoto N, Murakami A, Kamei C: Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats. Biol Pharm Bull. 2007 Mar;30(3):477-80. [PubMed:17329841 ]
  7. Havas TE, Cole P, Parker L, Oprysk D, Ayiomamitis A: The effects of combined H1 and H2 histamine antagonists on alterations in nasal airflow resistance induced by topical histamine provocation. J Allergy Clin Immunol. 1986 Nov;78(5 Pt 1):856-60. [PubMed:2878016 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
antagonist
General Function:
G-protein coupled acetylcholine receptor activity
Specific Function:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then trigge...
Gene Name:
CHRM2
Uniprot ID:
P08172
Uniprot Name:
Muscarinic acetylcholine receptor M2
Molecular Weight:
51714.605 Da
References
  1. Liu H, Zheng Q, Farley JM: Antimuscarinic actions of antihistamines on the heart. J Biomed Sci. 2006 May;13(3):395-401. [PubMed:16453179 ]

Enzymes

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrateinhibitor
General Function:
Steroid hydroxylase activity
Specific Function:
Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.
Gene Name:
CYP2D6
Uniprot ID:
P10635
Uniprot Name:
Cytochrome P450 2D6
Molecular Weight:
55768.94 Da
References
  1. Hamelin BA, Bouayad A, Drolet B, Gravel A, Turgeon J: In vitro characterization of cytochrome P450 2D6 inhibition by classic histamine H1 receptor antagonists. Drug Metab Dispos. 1998 Jun;26(6):536-9. [PubMed:9616188 ]
  2. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
  3. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
  4. Drug Interactions: Cytochrome P450 Drug Interaction Table [Link]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N...
Gene Name:
CYP1A2
Uniprot ID:
P05177
Uniprot Name:
Cytochrome P450 1A2
Molecular Weight:
58293.76 Da
References
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Steroid hydroxylase activity
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenyto...
Gene Name:
CYP2C9
Uniprot ID:
P11712
Uniprot Name:
Cytochrome P450 2C9
Molecular Weight:
55627.365 Da
References
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Steroid hydroxylase activity
Specific Function:
Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine.
Gene Name:
CYP2C19
Uniprot ID:
P33261
Uniprot Name:
Cytochrome P450 2C19
Molecular Weight:
55930.545 Da
References
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Steroid hydroxylase activity
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Gene Name:
CYP2C18
Uniprot ID:
P33260
Uniprot Name:
Cytochrome P450 2C18
Molecular Weight:
55710.075 Da
References
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Steroid hydroxylase activity
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,4-cineole 2-exo-monooxygenase.
Gene Name:
CYP2B6
Uniprot ID:
P20813
Uniprot Name:
Cytochrome P450 2B6
Molecular Weight:
56277.81 Da
References
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Prostaglandin-endoperoxide synthase activity
Specific Function:
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the gener...
Gene Name:
PTGS1
Uniprot ID:
P23219
Uniprot Name:
Prostaglandin G/H synthase 1
Molecular Weight:
68685.82 Da
References
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]

Transporters

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Quaternary ammonium group transmembrane transporter activity
Specific Function:
Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridiniu...
Gene Name:
SLC22A2
Uniprot ID:
O15244
Uniprot Name:
Solute carrier family 22 member 2
Molecular Weight:
62579.99 Da
References
  1. Urakami Y, Okuda M, Masuda S, Akazawa M, Saito H, Inui K: Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules. Pharm Res. 2001 Nov;18(11):1528-34. [PubMed:11758759 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Secondary active organic cation transmembrane transporter activity
Specific Function:
Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine...
Gene Name:
SLC22A1
Uniprot ID:
O15245
Uniprot Name:
Solute carrier family 22 member 1
Molecular Weight:
61153.345 Da
References
  1. Urakami Y, Okuda M, Masuda S, Akazawa M, Saito H, Inui K: Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules. Pharm Res. 2001 Nov;18(11):1528-34. [PubMed:11758759 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Symporter activity
Specific Function:
Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine. Transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Also relative uptake activity ratio of carnitine to TEA is 11.3.
Gene Name:
SLC22A5
Uniprot ID:
O76082
Uniprot Name:
Solute carrier family 22 member 5
Molecular Weight:
62751.08 Da
References
  1. Ohashi R, Tamai I, Nezu Ji J, Nikaido H, Hashimoto N, Oku A, Sai Y, Shimane M, Tsuji A: Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2. Mol Pharmacol. 2001 Feb;59(2):358-66. [PubMed:11160873 ]
Drug created on June 13, 2005 07:24 / Updated on September 01, 2017 10:35