Pheniprazine hydrochlorideProduct ingredient for Pheniprazine
- Name
- Pheniprazine hydrochloride
- Drug Entry
- Pheniprazine
Pheniprazine is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used as an antidepressant in the 1960s. In addition, it was used for the treatment of other conditions, such as angina pectoris and schizophrenia. Pheniprazine was withdrawn by its manufacturer due to its ability to cause toxicity in the liver and its ability to cause optic neuritis.
- Accession Number
- DBSALT001273
- Structure
Structure for Pheniprazine hydrochloride (DBSALT001273)
- Synonyms
- Pheniprazine HCl
- UNII
- 5B3OM8452C
- CAS Number
- 66-05-7
- Weight
- Average: 186.68
Monoisotopic: 186.0923762 - Chemical Formula
- C9H15ClN2
- InChI Key
- HXCTUSBYMZQLKB-UHFFFAOYSA-N
- InChI
- InChI=1S/C9H14N2.ClH/c1-8(11-10)7-9-5-3-2-4-6-9;/h2-6,8,11H,7,10H2,1H3;1H
- IUPAC Name
- (1-phenylpropan-2-yl)hydrazine hydrochloride
- SMILES
- Cl.CC(CC1=CC=CC=C1)NN
- External Links
- ChemSpider
- 4447512
- ChEMBL
- CHEMBL2106542
- Predicted Properties
Property Value Source Water Solubility 3.75 mg/mL ALOGPS logP 1.69 ALOGPS logP 1.62 Chemaxon logS -1.6 ALOGPS pKa (Strongest Basic) 5.65 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 38.05 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 58.68 m3·mol-1 Chemaxon Polarizability 17.47 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon