D-glucose monohydrateProduct ingredient for D-glucose

Name
D-glucose monohydrate
Drug Entry
D-glucose

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation.2 It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative.10 The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated.12 Glucose is listed on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.

Accession Number
DBSALT001507
Structure
Thumb
Synonyms
D-glucose, hydrate (1:1) / Dextrose hydrous / Dextrose monohydrate / Glucose monohydrate
UNII
LX22YL083G
CAS Number
77938-63-7
Weight
Average: 198.171
Monoisotopic: 198.073952791
Chemical Formula
C6H14O7
InChI Key
SPFMQWBKVUQXJV-BTVCFUMJSA-N
InChI
InChI=1S/C6H12O6.H2O/c7-1-3(9)5(11)6(12)4(10)2-8;/h1,3-6,8-12H,2H2;1H2/t3-,4+,5+,6+;/m0./s1
IUPAC Name
(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal hydrate
SMILES
O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O
External Links
ChemSpider
18532158
Predicted Properties
PropertyValueSource
Water Solubility261.0 mg/mLALOGPS
logP-2.4ALOGPS
logP-3.6ChemAxon
logS0.16ALOGPS
pKa (Strongest Acidic)12.26ChemAxon
pKa (Strongest Basic)-3ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count5ChemAxon
Polar Surface Area118.22 Å2ChemAxon
Rotatable Bond Count5ChemAxon
Refractivity37.35 m3·mol-1ChemAxon
Polarizability16.14 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon