Sodium seleniteProduct ingredient for Selenious acid

Name
Sodium selenite
Drug Entry
Selenious acid

Selenious acid is the acid form of sodium selenite, a form of selenium 8.

Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is a component of glutathione peroxidase enzyme, which protects cell components from oxidative damage due to peroxides produced during cellular metabolism 13.

Selenium (Se) has been demonstrated to prevent cancer in numerous animal models when administered selenium at levels exceeding the nutritional requirements. One study showed efficacy in the prevention of malignancy while utilizing a selenium supplement in humans. The reports from such studies have heightened the interest in additional human selenium supplementation studies to validate the results in larger populations 15.

Interestingly, selenium is being studied as a potential therapy in the prevention or management of atherosclerosis 18.

Accession Number
DBSALT001761
Structure
Thumb
Synonyms
Disodium selenite / Disodium selenium trioxide / Natriumselenit / Selenious acid disodium salt / Selenious acid, disodium salt / Selenious acid, sodium salt (1:2) / Sodium selenite anhydrous
UNII
HIW548RQ3W
CAS Number
10102-18-8
Weight
Average: 172.94
Monoisotopic: 173.880805044
Chemical Formula
Na2O3Se
InChI Key
BVTBRVFYZUCAKH-UHFFFAOYSA-L
InChI
InChI=1S/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2
IUPAC Name
disodium selenite
SMILES
[Na+].[Na+].[O-][Se]([O-])=O
External Links
KEGG Compound
C18385
ChemSpider
23308
ChEBI
48843
ChEMBL
CHEMBL112302
Wikipedia
Sodium_selenite
Predicted Properties
PropertyValueSource
logP-1.3ChemAxon
pKa (Strongest Acidic)11.93ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area63.19 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity17.44 m3·mol-1ChemAxon
Polarizability5.32 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon