Name
Ferrous sulfate
Drug Entry
Ferrous sulfate anhydrous

Ferrous sulfate is also known as Green vitriol. It is of synthetic origin and belongs to the pharmacological groups called hematological agents and iron salts. The molecular weight of ferrous sulfate is 278.00 11. This medication is an iron supplement used to treat or prevent low blood levels of iron (e.g., for anemia or during pregnancy) 18.

Twice the number of ferrous gluconate or ferrous fumarate tablets (other forms of iron for ingestion) are required to provide the amount of elemental iron in ferrous sulfate tablets 22. For this reason, ferrous sulfate is the gold standard (most commonly prescribed) oral iron therapy in the UK and many other countries 10.

Interestingly, research has demonstrated that unabsorbed dietary iron may possibly increase free radical production in the colon to concentrations that could lead to mucosal cell damage or increased production of carcinogens 33, 34.

Accession Number
DBSALT002666
Structure
Thumb
Synonyms
copperas / Fero-Gradumet / Ferrous sulfate heptahydrate / Ferrous sulfate, heptahydrate / Ferrous sulphate heptahydrate / green vitriol / iron vitriol / iron(2+) sulfate heptahydrate / Iron(II) sulfate heptahydrate / melanterite / melanterite mineral
UNII
39R4TAN1VT
CAS Number
7782-63-0
Weight
Average: 278.015
Monoisotopic: 277.960624113
Chemical Formula
FeH14O11S
InChI Key
SURQXAFEQWPFPV-UHFFFAOYSA-L
InChI
InChI=1S/Fe.H2O4S.7H2O/c;1-5(2,3)4;;;;;;;/h;(H2,1,2,3,4);7*1H2/q+2;;;;;;;;/p-2
IUPAC Name
lambda2-iron(2+) heptahydrate sulfate
SMILES
O.O.O.O.O.O.O.[Fe++].[O-]S([O-])(=O)=O
External Links
KEGG Drug
D01725
ChemSpider
56413
ChEBI
75836
Wikipedia
Iron(II)_sulfate
Predicted Properties
PropertyValueSource
logP-0.84ChemAxon
pKa (Strongest Acidic)-3ChemAxon
Physiological Charge-2ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area80.26 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity11.53 m3·mol-1ChemAxon
Polarizability5.81 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon