Ropivacaine hydrochloride anhydrousProduct ingredient for Ropivacaine
- Name
- Ropivacaine hydrochloride anhydrous
- Drug Entry
- Ropivacaine
Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.2
- Accession Number
- DBSALT002892
- Structure
Structure for Ropivacaine hydrochloride anhydrous (DBSALT002892)
- Synonyms
- Ropivacaine HCl anhydrous
- UNII
- 35504LBE2T
- CAS Number
- 98717-15-8
- Weight
- Average: 310.87
Monoisotopic: 310.1811912 - Chemical Formula
- C17H27ClN2O
- InChI Key
- NDNSIBYYUOEUSV-RSAXXLAASA-N
- InChI
- InChI=1S/C17H26N2O.ClH/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H/t15-;/m0./s1
- IUPAC Name
- (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride
- SMILES
- Cl.CCCN1CCCC[C@H]1C(=O)NC1=C(C)C=CC=C1C
- External Links
- ChemSpider
- 153164
- ChEBI
- 60803
- ChEMBL
- CHEMBL1889140
- Predicted Properties
Property Value Source Water Solubility 0.253 mg/mL ALOGPS logP 2.91 ALOGPS logP 4.07 Chemaxon logS -3 ALOGPS pKa (Strongest Acidic) 13.62 Chemaxon pKa (Strongest Basic) 7.82 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 32.34 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 85.59 m3·mol-1 Chemaxon Polarizability 32.9 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon