Potassium oxybateProduct ingredient for gamma-Hydroxybutyric acid
- Name
- Potassium oxybate
- Drug Entry
- gamma-Hydroxybutyric acid
Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple countries. It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. However, it is important to note that GHB is a designated Orphan drug (in 1985). Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem falls under penalties of Schedule I. GHB is a naturally occurring substance found in the central nervous system, wine, beef, small citrus fruits and almost all other living creatures in small amounts. It is used illegally under the street names Juice, Liquid Ecstasy or simply G, either as an intoxicant, or as a date rape drug. Xyrem is a central nervous system depressant that reduces excessive daytime sleepiness and cataplexy in patients with narcolepsy.
- Accession Number
- DBSALT002967 (DB15755)
- Structure
Structure for Potassium oxybate (DBSALT002967)
- Synonyms
- 4-Hydroxybutanoic acid potassium salt / 4-Hydroxybutyric acid potassium salt / Oxybate potassium
- UNII
- S8NKF3H3KT
- CAS Number
- 57769-01-4
- Weight
- Average: 142.195
Monoisotopic: 142.00322558 - Chemical Formula
- C4H7KO3
- InChI Key
- TXSIWDVUJVMMKM-UHFFFAOYSA-M
- InChI
- InChI=1S/C4H8O3.K/c5-3-1-2-4(6)7;/h5H,1-3H2,(H,6,7);/q;+1/p-1
- IUPAC Name
- potassium 4-hydroxybutanoate
- SMILES
- [K+].OCCCC([O-])=O
- External Links
- ChemSpider
- 8096044
- Wikipedia
- Gamma-Hydroxybutyric_acid
- Predicted Properties
Property Value Source Water Solubility 522.0 mg/mL ALOGPS logP -0.37 ALOGPS logP -0.51 Chemaxon logS 0.56 ALOGPS pKa (Strongest Acidic) 4.44 Chemaxon pKa (Strongest Basic) -2.4 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 60.36 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 34.64 m3·mol-1 Chemaxon Polarizability 9.74 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon