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Displaying all 9 drugs

Dihydro-alpha-ergocryptine

Alpha-dihydroergocryptine is usually referred to the mixture of the alpha and beta dihydroergocryptine. These two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine. Both compounds are hydrogenated ergot derivatives. Alpha-dihydroergocryptine approved drug product...
Approved
Matched Description: … This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine ... Alpha-dihydroergocryptine is usually referred to the mixture of the alpha and beta dihydroergocryptine …

Bacitracin

Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Bacitracin Zinc ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Up and Up First Aid Antibiotic ... Up and Up Bacitracin first aid …

Bivalirudin

Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in...
Approved
Investigational
Matched Description: … monitor changes in hematocrit, activated partial thromboplastin time, international normalized ratio and …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …

Valine

Valine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
Approved
Nutraceutical
Matched Description: … It promotes muscle growth and tissue repair. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Lepirudin

Lepirudin is a recombinant hirudin formed by 65 amino acids that acts as a highly specific and direct thrombin inhibitor.[L41539,L41569] Natural hirudin is an endogenous anticoagulant found in Hirudo medicinalis leeches. Lepirudin is produced in yeast cells and is identical to natural hirudin except for the absence of sulfate on...
Approved
Withdrawn
Matched Description: … of sulfate on the tyrosine residue at position 63 and the substitution of leucine for isoleucine at ... This activates endothelial cells and platelets and enhances the formation of thrombi. ... Lepirudin is a recombinant hirudin formed by 65 amino acids that acts as a highly specific and direct …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …

Semaglutide

Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity.[A31421,L8681] Other members of this drug class include Exenatide and Liraglutide. Semaglutide was developed by Novo Nordisk and approved by the FDA for subcutaneous injection...
Approved
Investigational
Matched Description: … and reducing blood glucose. ... [A31421,L8681] Other members of this drug class include [Exenatide] and [Liraglutide]. ... 1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Isoleucine

An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of leucine. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.
Investigational
Nutraceutical
Matched Synonyms: … Isoleucine ... L-Isoleucine …
Matched Name: … Isoleucine …
Matched Description: … It is an isomer of leucine. ... It is important in hemoglobin synthesis and regulation of blood sugar and energy levels. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Leucine

An essential branched-chain amino acid important for hemoglobin formation.
Investigational
Nutraceutical
Matched Synonyms: … Leucine ... L-Leucine ... (S)-Leucine …
Matched Name: … Leucine …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Salts name: … L-Leucine hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Obinepitide

Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which normally are released during a meal. These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from the GI-tract to the CNS. In obinepitide,...
Investigational
Matched Description: … Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which ... These hormones are known to play a role in the regulation of food intake and appetite in man as satiety …
Displaying all 9 drugs