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Displaying drugs 3576 - 3600 of 11853 in total
Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171] Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Description: … [A189901] Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications …
Regdanvimab (CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. It blocks the interaction between viral spike proteins and angiotensin-converting enzyme 2 (ACE2) that allows for viral entry into the cell, thereby inhibiting the virus' ability to replicate. Trials...
Approved
Investigational
Matched Description: … Regdanvimab (CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding ... Trials investigating the use of regdanvimab as a therapeutic candidate for the treatment of COVID-19 …
Agave sisalana fiber is used in allergenic testing.
Approved
Iva axillaris pollen is the pollen of the Iva axillaris plant. Iva axillaris pollen is mainly used in allergenic testing.
Approved
Apiospora montagnei is a fungus which can provoke allergic reactions. Apiospora montagnei extract is used in allergenic testing.
Approved
Matched Description: … Apiospora montagnei is a fungus which can provoke allergic reactions. …
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Description: … a higher diuretic potential. ... Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from ... Furosemide has a fast onset and short duration of action and has been used safely and effectively in …
An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Approved
Investigational
Matched Description: … It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, …
A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Approved
Investigational
Matched Description: … A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. …
Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography (PET) imaging of the brain. It is used for the non-invasive detection of the density of ß-amyloid neuritic plaques in the brain of adult patients with cognitive impairment.
Approved
Matched Description: … Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography …
Deucravacitinib is a novel oral selective tyrosine kinase 2 (TYK2) inhibitor. Unlike other Janus kinase 1/2/3 inhibitors that bind to the conserved active domain of these non-receptor tyrosine kinases, deucravacitinib binds to the regulatory domain of TYK2 with high selectivity to this therapeutic target.[A246938, A246943] This selectivity towards TYK2 may...
Approved
Investigational
Matched Description: … Deucravacitinib is a novel oral selective tyrosine kinase 2 (TYK2) inhibitor. ... to an improved safety profile of deucravacitinib, as nonselective JAK inhibitors are associated with a
Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.[label] It mainly works by depressing the chemoreceptor trigger zone and blocking...
Approved
Vet approved
Matched Description: … Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic …
An alkylating agent of value against both hematologic malignancies and solid tumors.
Approved
Investigational
Approved
Experimental
Evinacumab is a recombinant human IgG4 monoclonal antibody targeted against angiopoietin-like protein 3 (ANGPTL3) and the first drug of its kind. The ANGPTL family of proteins serve a number of physiologic functions - including involvement in the regulation of lipid metabolism - which have made them desirable therapeutic targets in...
Approved
Investigational
Matched Description: … rationale for the development of a therapy targeted against ANGPTL3. ... Evinacumab is a recombinant human IgG4 monoclonal antibody targeted against angiopoietin-like protein ... The ANGPTL family of proteins serve a number of physiologic functions - including involvement in the …
Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Approved
Investigational
Matched Description: … Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B …
Magnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group . It is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking agent, opacifying agent, viscosity-increasing agent, suspending agent, tablet and capsule disintegrant, and tablet binder. It also...
Approved
Matched Description: … Magnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite ... It is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking ... It also has antacid properties and is used as a component of some over the counter antacid medications …
Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , . One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Description: … One of the most common uses for this drug is for a condition called _allergic rhinitis_. …
Solenopsis invicta allergenic extract is used in allergenic testing.
Approved
Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. Major brands of zuclopenthixol are Cisordinol, Acuphase, and Clopixol. This drug is a liquid. This compound...
Approved
Investigational
Matched Description: … This drug is a liquid. This compound belongs to the thioxanthenes. ... derived from xanthene by replacing the oxygen atom with a sulfur atom. ... Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine …
Iobenguane sulfate I-123 is a radiopharmaceutical used in gamma-scintigraphy of adrenergically inervated tissues [FDA Label].
Approved
Investigational
Matched Description: … Iobenguane sulfate I-123 is a radiopharmaceutical used in gamma-scintigraphy of adrenergically inervated …
Aspergillus nidulans is a fungus which can provoke allergic reactions. Aspergillus nidulans extract is used in allergenic testing.
Approved
Matched Description: … Aspergillus nidulans is a fungus which can provoke allergic reactions. …
Naloxegol, for "PEGylated naloxol" is a peripherally-selective opioid antagonist developed by AstraZeneca. It was approved by the FDA in September 2014 and is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non‑cancer pain. The advantage of naloxegol over the opioid antagonist naloxone is that its...
Approved
Matched Description: … Naloxegol, for "PEGylated naloxol" is a peripherally-selective opioid antagonist developed by AstraZeneca …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A181036,A181039] Metronidazole has been used as an antibiotic for several decades , with added antiparasitic properties that set...
Approved
Matched Description: … Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. ... antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat a
Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor dabigatran.[A177463, A6970, L34675, L34680] Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom anticoagulation therapy is indicated. In contrast to warfarin, because its anticoagulant effects...
Approved
Displaying drugs 3576 - 3600 of 11853 in total