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Displaying drugs 15251 - 15275 of 15280 in total

Milatuzumab

Milatuzumab has been used in trials studying the treatment of Lupus Nephritis, Multiple Myeloma (MM), GVHD (Acute or Chronic), Myelodysplastic Syndrome, and Chronic Lymphocytic Leukemia, among others.
Investigational
Matched Description: … Milatuzumab has been used in trials studying the treatment of Lupus Nephritis, Multiple Myeloma (MM), …

Rovalpituzumab tesirine

Rovalpituzumab Tesirine has been used in trials studying the treatment of GLIOBLASTOMA, Malignant Melanoma, Other Solid Tumors, Small Cell Lung Cancer, and Medullary Thyroid Cancer, among others.
Investigational
Matched Description: … Rovalpituzumab Tesirine has been used in trials studying the treatment of GLIOBLASTOMA, Malignant Melanoma …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

TZP-102

TZP-102 is under investigation in clinical trial NCT01452815 (Affects of Once-daily Oral Administration of TZP-102 on the Treatment of Symptoms Associated With Diabetic Gastroparesis).
Investigational
Matched Iupac: … (2R,5S,8R,11R,14S)-5-cyclopropyl-2,7,8,14-tetramethyl-11-(2-methylpropyl)-3,4,5,6,7,8,9,10,11,12,13,14,15,16 …
Matched Description: … TZP-102 is under investigation in clinical trial NCT01452815 (Affects of Once-daily Oral Administration …

D-Treitol

A four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator. [PubChem]
Experimental
Matched Description: … A four-carbon sugar that is found in algae, fungi, and lichens. ... It is twice as sweet as sucrose and can be used as a coronary vasodilator. [PubChem] …

Pictilisib

Pictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid Tumours, Metastatic Breast Cancer, and Non-Hodgkin's Lymphoma, Solid Cancers, among others.
Investigational
Matched Iupac: … 4-{6-[(4-methanesulfonylpiperazin-1-yl)methyl]-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl}-1H-indazole …
Matched Description: … Pictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …

MK-0767

MK0767 has been used in trials studying the treatment of Dyslipidemia, Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, and Diabetes Mellitus, Type II, among others.
Investigational
Matched Iupac: … 5-[(2,4-dioxo-1,3-oxazolidin-5-yl)methyl]-2-methoxy-N-{[4-(trifluoromethyl)phenyl]methyl}benzamide …
Matched Description: … MK0767 has been used in trials studying the treatment of Dyslipidemia, Diabetes Mellitus, Type 2 Diabetes ... Mellitus, Diabetes Mellitus, Type 2, and Diabetes Mellitus, Type II, among others. …

Tesidolumab

Tesidolumab has been used in trials studying the treatment of Geographic Atrophy, Non-infectious Panuveitis, Exudative Macular Degeneration, Non-infectious Posterior Uveitis, and Age-related Macular Degeneration, among others.
Investigational
Matched Description: … Tesidolumab has been used in trials studying the treatment of Geographic Atrophy, Non-infectious Panuveitis …

Dusigitumab

Dusigitumab has been used in trials studying the treatment of Cancer, Advanced Solid Malignancies, Unresectable or Metastatic Hepatocellular Carcinoma (HCC), and Hormone-sensitive, HER-2 Negative Metastatic Breast Cancer.
Investigational
Matched Description: … or Metastatic Hepatocellular Carcinoma (HCC), and Hormone-sensitive, HER-2 Negative Metastatic Breast ... Dusigitumab has been used in trials studying the treatment of Cancer, Advanced Solid Malignancies, Unresectable …

VTX-801

VTX-801 is a replication-deficient recombinant adeno-associated viral vector (rAAV) consisting of an AAV liver tropic capsid containing a single-stranded DNA genome carrying a shortened version of the ATP7B gene (ATP7B-minigene). It is being investigated in Wilson Disease.
Investigational
Matched Description: … It is being investigated in Wilson Disease.[L45924] ... AAV liver tropic capsid containing a single-stranded DNA genome carrying a shortened version of the ATP7B ... VTX-801 is a replication-deficient recombinant adeno-associated viral vector (rAAV) consisting of an …

Methyl undecenoyl leucinate

Methyl undecenoyl leucinate is an active ingredient in whitening creams. It is an α-MSH antagonist that inhibits melanin synthesis and tyrosinase activity and reduces expression of various melanogenic genes.
Experimental
Matched Iupac: … methyl (2S)-4-methyl-2-(undec-10-enamido)pentanoate …
Matched Description: … Methyl undecenoyl leucinate is an active ingredient in whitening creams. …

Rivipansel

Rivipansel has been used in trials studying the other, basic science, and treatment of Pain Crisis, Renal impairment, Anemia, Sickle Cell, Sickle Cell Disease, and Sickle Cell Disorders, among others.
Investigational
Matched Iupac: … (2S)-2-{[(2R,3R,4S,5S,6R)-3-(benzoyloxy)-2-{[(1R,2R,3S,5R)-3-(2,6-dioxo-1,2,3,6-tetrahydropyrimidine- ... 4-amido)-2-{[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}-5-({2-[2-(2-{[(3,6,8-trisulfonaphthalen ... ]methoxy}ethoxy)acetamido]ethyl}carbamoyl)cyclohexyl]oxy}-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-3- …
Matched Description: … Rivipansel has been used in trials studying the other, basic science, and treatment of Pain Crisis, Renal …
Matched Salts cas: … 1189037-60-2 …

Vaniprevir

Vaniprevir has been used in trials studying the treatment and diagnostic of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, Chronic Hepatitis C Infection, and Chronic Genotype 1 Hepatitis C Virus Infection.
Investigational
Matched Iupac: … (1R,21S,24S)-21-tert-butyl-N-[(1R,2R)-1-[(cyclopropanesulfonyl)carbamoyl]-2-ethylcyclopropyl]-16,16-dimethyl …
Matched Description: … Vaniprevir has been used in trials studying the treatment and diagnostic of Hepatitis C, Chronic Hepatitis ... C, Hepatitis C, Chronic, Chronic Hepatitis C Infection, and Chronic Genotype 1 Hepatitis C Virus Infection …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Ronacaleret

Ronacaleret is a calcium-sensing receptor antagonist.
Investigational
Matched Iupac: … 3-{3-[(2R)-3-{[1-(2,3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl]amino}-2-hydroxypropoxy]-4,5-difluorophenyl …
Matched Description: … Ronacaleret is a calcium-sensing receptor antagonist. …
Matched Salts cas: … 702686-96-2 …

Onatasertib

Onatasertib (CC-223) has been used in trials studying the treatment and basic science of Multiple Myeloma, Glioblastoma Multiforme, HepatoCellular Carcinoma, Non-small Cell Lung Cancer, and Diffuse Large B-Cell Lymphoma, among others.
Investigational
Matched Iupac: … 7-[6-(2-hydroxypropan-2-yl)pyridin-3-yl]-1-[(1r,4r)-4-methoxycyclohexyl]-1H,2H,3H,4H-pyrazino[2,3-b][ ... 1,4]diazin-2-one …
Matched Description: … Onatasertib (CC-223) has been used in trials studying the treatment and basic science of Multiple Myeloma …

Ontuxizumab

Ontuxizumab is a humanized monoclonal antibody that targets endosialin or tumour endothelial marker 1 (TEM-1). It is under investigation in clinical trial NCT01574716 (Sarcoma Study of Morab-004 Utilization: Research and Clinical Evaluation).
Investigational
Matched Description: … Ontuxizumab is a humanized monoclonal antibody that targets endosialin or tumour endothelial marker 1 ... It is under investigation in clinical trial NCT01574716 (Sarcoma Study of Morab-004 Utilization: Research …

ONT-093

ONT-093 is an orally bioavailable inhibitor of P-glycoprotein (P-gp). In pre-clinical studies, ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations with no effect on paclitaxel pharmacokinetics.
Investigational
Matched Iupac: … 4-(2-{4-[(1E)-3-ethoxyprop-1-en-1-yl]phenyl}-4-{4-[(propan-2-yl)amino]phenyl}-1H-imidazol-5-yl)-N-(propan ... -2-yl)aniline …
Matched Description: … In pre-clinical studies, ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations …

Difloxacin

Difloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. However, it presents a reduced efficacy when compared to other fluoroquinolone antibacterials.
Vet approved
Matched Iupac: … 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Difloxacin is a synthetic fluoroquinolone used in veterinary. ... However, it presents a reduced efficacy when compared to other fluoroquinolone antibacterials. ... As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Onapristone

Onapristone has been used in trials studying the treatment of Prostate Cancer, Recurrent Prostate Cancer, Metastatic Prostate Cancer, Androgen-independent Prostate Cancer, and Progesterone Receptor Positive Tumor: Max 1 Line of Prior Chemotherapy, no Prior Hormone Therapy.
Investigational
Matched Iupac: … (10S,11S,14S,15R,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-14-(3-hydroxypropyl)-15-methyltetracyclo …
Matched Description: … Onapristone has been used in trials studying the treatment of Prostate Cancer, Recurrent Prostate Cancer …

Stepronin

Strepronin is a mucolytic drug. A mucolytic agent is any agent which dissolves thick mucus usually used to help relieve respiratory difficulties. The viscosity of mucous secretions in the lungs is dependent upon the concentrations of mucoprotein as well as the presence of disulfide bonds between these macromolecules and DNA.
Experimental
Matched Iupac: … 2-[2-(thiophene-2-carbonylsulfanyl)propanamido]acetic acid …
Matched Description: … Strepronin is a mucolytic drug. ... The viscosity of mucous secretions in the lungs is dependent upon the concentrations of mucoprotein as ... A mucolytic agent is any agent which dissolves thick mucus usually used to help relieve respiratory difficulties …

Deferitazole

Deferitazole is an iron chelator. It has been used in trials studying the treatment and basic science of Beta-thalassemia, Hepatic Impairment, Impaired Renal Function, Transfusional Iron Overload, and Iron Overload Due to Repeated Red Blood Cell Transfusions.
Investigational
Matched Iupac: … (4S)-2-(2-hydroxy-3-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}phenyl)-4-methyl-4,5-dihydro-1,3-thiazole-4- …
Matched Description: … It has been used in trials studying the treatment and basic science of Beta-thalassemia, Hepatic Impairment …

Dimenoxadol

Dimenoxadol is an opioid analgesic which produces typical opioid effects such as analgesia and sedation. It is structurally similar to methadone and is a benzilic acid derivative. In the United States it is classified as a Schedule I controlled drug.
Experimental
Illicit
Matched Iupac: … 2-(dimethylamino)ethyl 2-ethoxy-2,2-diphenylacetate …
Matched Description: … In the United States it is classified as a Schedule I controlled drug. ... It is structurally similar to methadone and is a benzilic acid derivative. …

Brifentanil

Brifentanil (also known as A-3331) is an analog of fentanyl, a potent opioid. This drug is classified as an opioid analgesic and was developed in the early 1990s. The effects of brifentanil are very similar to those of alfentanil, with strong but short lasting analgesia and sedation, and particularly notable...
Illicit
Matched Iupac: … N-[(3R,4S)-1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-1,2,3,4-tetrazol-1-yl)ethyl]-3-methylpiperidin-4-yl]-N- ... (2-fluorophenyl)-2-methoxyacetamide …
Matched Description: … Brifentanil (also known as A-3331) is an analog of fentanyl, a potent opioid. ... This drug is classified as an opioid analgesic and was developed in the early 1990s. …

Merbromin

Mercurochrome is a trade name of merbromin commonly used as a topical first-aid antiseptic agent. It is an organomercuric disodium salt compound and a fluorescein that is available in many countries, except Switzerland, France, Germany, and the United States where the drug was withdrawn from market due to the possibility...
Experimental
Matched Iupac: … disodium [2,7-dibromo-9-(2-carboxylatophenyl)-6-oxido-3-oxo-3H-xanthen-5-yl]mercurol …
Matched Description: … It is an organomercuric disodium salt compound and a fluorescein that is available in many countries, ... Mercurochrome is a trade name of merbromin commonly used as a topical first-aid antiseptic agent. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …

S-Hydroxycysteine

S-hydroxycysteine is a solid. This compound belongs to the alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof. It targets the proteins subtilisin BPN', glutathione S-transferase A1,...
Experimental
Matched Iupac: … (2R)-2-amino-3-(hydroxysulfanyl)propanoic acid …
Matched Description: … These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to ... the carboxylate group (alpha carbon), or a derivative thereof. ... S-hydroxycysteine is a solid. This compound belongs to the alpha amino acids and derivatives. …

Zilpaterol

Zilpaterol is a β2 adrenergic agonist sold under the trade name, Zilmax, produced by Intervet, a subsidiary of Merck & Co. Zilpaterol is typically fed to cattle in the last three to six weeks of life with a brief washout period to clear the drug from the tissues before slaughter.
Vet approved
Matched Iupac: … (9R,10R)-9-hydroxy-10-[(propan-2-yl)amino]-1,3-diazatricyclo[6.4.1.0^{4,13}]trideca-4,6,8(13)-trien-2 …
Matched Description: … Zilpaterol is typically fed to cattle in the last three to six weeks of life with a brief washout period ... Zilpaterol is a β2 adrenergic agonist sold under the trade name, Zilmax, produced by Intervet, a subsidiary …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 15251 - 15275 of 15280 in total