Displaying drugs 4551 - 4575 of 11853 in total
N-Carbamoylaspartic acid
Experimental
Odanacatib
Odanacatib is an inhibiter of cathepsin K which was originally developed be Merck & Co as a new treatment for osteoporosis . The drug made it to phase III trials before abandoned due to increased stroke.
Investigational
Matched Description: … Odanacatib is an inhibiter of cathepsin K which was originally developed be Merck & Co as a new treatment …
Cobnabexagene anvuparvovec
Experimental
Aluminum cation
Experimental
Colforsin
Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.
Experimental
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Anti-CD5 CAR T-cell therapy
Investigational
AVI-4557
AVI-4557 is an oral antisense compound that selectively inhibits the metabolic enzyme cytochrome P450 3A4 (CYP), a liver enzyme responsible for the metabolism or breakdown of approximately half of currently marketed drugs. Studies indicate that AVI-4557 can successfully reduce the rate of metabolism for certain drugs, therefore allowing greater and...
Investigational
Matched Description: … an oral antisense compound that selectively inhibits the metabolic enzyme cytochrome P450 3A4 (CYP), a ... drugs, therefore allowing greater and longer availability of the drug in the patient's system through a ... toxicity for patients receiving highly-toxic therapeutic drugs for treatment of anxiety, cancer, and a …
Prademagene zamikeracel
Investigational
17Alpha-methyl-3beta,17beta-dihydroxy-5alpha-androstane
Experimental
Illicit
Matched Iupac: … (1S,3aS,3bR,5aS,7S,9aS,9bS,11aS)-1,9a,11a-trimethyl-hexadecahydro-1H-cyclopenta[a]phenanthrene-1,7-diol …
Equilenin
Equilenin is an estrogenic steroid produced by horses. It has a total of five double bonds in the A- and B-ring. High concentration of equilenin is found in the urine of pregnant mares.
Experimental
Matched Iupac: … (3aS,11aS)-7-hydroxy-11a-methyl-1H,2H,3H,3aH,10H,11H,11aH-cyclopenta[a]phenanthren-1-one …
Matched Description: … It has a total of five double bonds in the A- and B-ring. …
Matched Description: … It has a total of five double bonds in the A- and B-ring. …
ABT-639
ABT-639 is under investigation in clinical trial NCT01345045 (A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain).
Investigational
Matched Iupac: … 5-[(8aR)-octahydropyrrolo[1,2-a]pyrazine-2-carbonyl]-4-chloro-2-fluoro-N-(2-fluorophenyl)benzene-1-sulfonamide …
Matched Description: … ABT-639 is under investigation in clinical trial NCT01345045 (A Multicenter Study Comparing the Analgesic …
Matched Description: … ABT-639 is under investigation in clinical trial NCT01345045 (A Multicenter Study Comparing the Analgesic …
Buloxibutid
Investigational
Myrtecaine
Experimental
Matched Iupac: … (2-{2-[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]ethoxy}ethyl)diethylamine …
Cotoretigene toliparvovec
Investigational
NKG2D-ACE2 CAR-NK Cell
These cells are prepared as universal off-the-shelf CAR-NK cells from cord blood with NKG2D-ACE2 proteins engineered as part of the CARs; the cell secretes IL-15 and GM-CSF. Chimeric antigen receptors (CARs) are artificial receptors consisting of an antibody-derived antigen binding domain and transmembrane and signaling domains from T-cell receptor signalling...
Investigational
Matched Description: … The GM-CSF acts as a neutralizer for the CAR-T cell-mediated cytokine release and neurotoxicity. ... The ACE2 is a receptor for SARS-Cov-2, binding to the S-protein of the viral envelope and competitively …
13-cis-12-(3'-Carboxyphenyl)retinoic acid
Experimental
Matched Categories: … Vitamin A ... Phospholipases A, antagonists & inhibitors …
Piboserod
Piboserod (SB 207266) is a selective 5-HT(4) receptor antagonist.
Investigational
Matched Iupac: … N-[(1-butylpiperidin-4-yl)methyl]-2H,3H,4H-[1,3]oxazino[3,2-a]indole-10-carboxamide …
Matched Description: … Piboserod (SB 207266) is a selective 5-HT(4) receptor antagonist. …
Matched Description: … Piboserod (SB 207266) is a selective 5-HT(4) receptor antagonist. …
3-AMINO-3-BENZYL-9-CARBOXAMIDE[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE
Experimental
Matched Iupac: … (1S,7S)-7-amino-7-benzyl-8-oxo-hexahydro-1H-pyrazolo[1,2-a]pyridazine-1-carbaldehyde …
(R)-Praziquantel
(R)-Praziquantel is under investigation in clinical trial NCT02271984 (Relative Bioavailability Trial of L-Praziquantel in Healthy Volunteers).
Investigational
Matched Iupac: … (11bR)-2-cyclohexanecarbonyl-1H,2H,3H,4H,6H,7H,11bH-pyrazino[2,1-a]isoquinolin-4-one …
Enarodustat
Enarodustat is under investigation in clinical trial NCT02581124 (Study to Evaluate Effect of Lapatinib on Pharmacokinetics of JTZ-951 in Subjects With End-stage Renal Disease).
Investigational
Matched Iupac: … 2-{[7-hydroxy-5-(2-phenylethyl)-[1,2,4]triazolo[1,5-a]pyridin-8-yl]formamido}acetic acid …
Androstanedione
Experimental
Illicit
Matched Iupac: … (3aS,3bR,5aS,9aS,9bS,11aS)-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthrene-1,7-dione …
Etiocholanedione
Experimental
Matched Iupac: … (3aS,3bR,5aR,9aS,9bS,11aS)-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthrene-1,7-dione …
Displaying drugs 4551 - 4575 of 11853 in total