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Displaying drugs 5201 - 5225 of 11434 in total
Experimental
An octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula occludens toxin) secreted by Vibrio cholerae for treatment of Coeliac disease.
Investigational
Matched Description: … An octapeptide inhibitor of paracellular permeability whose structure is derived from a protein (zonula …
Acediasulfone (INN) is an antimicrobial and antimalarial long-acting prodrug of dapsone.
Experimental
Maduramicin is an antiprotozoal agent used in veterinary medicine as prophylaxis against coccidiosis. It is a naturally occurring compound which was first isolated from the actinomycete, Actinomadura rubra.
Vet approved
Matched Description: … It is a naturally occurring compound which was first isolated from the actinomycete, Actinomadura rubra …
Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis.[L27246, L27256] This drug has potential application for radiation-induced esophagitis and oral mucositis, in addition to being currently tested against COVID-19.
Investigational
Matched Description: … Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide …
An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem]
Experimental
Vet approved
Matched Description: … An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Experimental
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Butylphthalide has been used in trials studying the prevention of Restenosis.
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. It is an outdated drug, and its approval has been discontinued by the FDA. Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. The sodium salt of a mercury-containing derivative of salicylamide, was formerly...
Experimental
Matched Description: … Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. ... The sodium salt of a mercury-containing derivative of salicylamide, was formerly used (often in combination …
Apadenoson is a selective A2a adenosine receptor agonist designed for use as a pharmacologic stress agent in cardiac perfusion imaging studies. It is developed by Bristol-Myers Squibb and is in phase II of clinical trials.
Investigational
Matched Description: … Apadenoson is a selective A2a adenosine receptor agonist designed for use as a pharmacologic stress agent …
Matched Categories: … Adenosine A receptor agonists …
Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin, based on evidence of the drug potently disrupting topoisomerase I and II activity at nanomolar drug concentrations and triggering cell...
Experimental
Matched Description: … Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
Experimental
Matched Categories: … Monoamine Oxidase A Inhibitors …
Vitamin A-analog that increases diffusivity of oxygen in aqueous solutions, including plasma.
Investigational
Matched Description: … Vitamin A-analog that increases diffusivity of oxygen in aqueous solutions, including plasma. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Vet approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor modulator (SERM). Droloxifene also exhibits more rapid pharmacokinetics, reaching peak concentrations and being eliminated much more rapidly than tamoxifen. Its higher affinity to the estrogen receptor, higher anti-estrogenic to estrogenic ratio, more effective inhibition of cell...
Investigational
Matched Description: … Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor ... It may have a particular role in situations in which rapid pharmacokinetics, or an increased antiestrogenic ... Droloxifene may also be a potentially useful agent for the treatment of postmenopausal osteoporosis because …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Nonivamide is found in herbs and spices. It is an alkaloid from the Capsicum species. The structures of DB06774 and nonivamide differ only slightly with respect to the fatty acid moiety of the side chain (8-methyl nonenoic acid versus nonanoic acid) . Nonivamide is a flavoring ingredient. Nonivamide is an...
Investigational
Matched Description: … Nonivamide is a flavoring ingredient. Nonivamide is an organic compound and a capsaicinoid. ... It is naturally found in chili peppers but manufactured to produce a synthetic form for various pharmacologic …
Experimental
Ofranergene obadenovec is under investigation in clinical trial NCT01229865 (Safety and Efficacy of VB-111 in Subjects With Advanced Differentiated Thyroid Cancer).
Investigational
Amitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. Amitraz presents insect repellent effects and hence, it can be used as an insecticide and pesticide. Its insecticide effect is due to its agonistic activity in the alpha-adrenergic system, its interaction with...
Experimental
Vet approved
Matched Description: … It was generated in 1969 by the Boots Co. in England. ... Amitraz is a non-systemic acaricide and insecticide. ... Amitraz presents a lower effect in mammals and thus, it is widely used in the treatment of mite- or tick-infestation …
Matched Categories: … Compounds used in a research, industrial, or household setting …
AMY-101, also known as compstatin 40, is a peptidic inhibitor of the central complement component C3. AMY-101 is under investigation in clinical trial NCT03694444 (A Study of the C3 Complement Inhibitor AMY-101 in Adults With Gingivitis).
Investigational
Matched Description: … AMY-101, also known as compstatin 40, is a peptidic inhibitor of the central complement component C3. ... AMY-101 is under investigation in clinical trial NCT03694444 (A Study of the C3 Complement Inhibitor …
Displaying drugs 5201 - 5225 of 11434 in total