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Displaying drugs 3501 - 3525 of 3718 in total

P-113D

P-113D is a novel 12 amino-acid antimicrobial peptide drug derived from histatins, which are compounds found naturally in human saliva. It is being pursued as a potential treatment for cystic fibrosis by Demegen, Inc.
Investigational

Cannabinol

Cannabinol (CBN) is a physiologically inactive constituent of Cannabis sativa.
Experimental
Investigational
Matched Synonyms: … 6,6,9-Trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol …
Matched Iupac: … 6,6,9-trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol …

Itopride

Itopride is a dopamine D2 antagonist with acetylcholinesterase inhibitory actions.
Investigational
Matched Synonyms: … N-(p-(2-(Dimethylamino)ethoxy)benzyl)veratramide …
Matched Iupac: … N-({4-[2-(dimethylamino)ethoxy]phenyl}methyl)-3,4-dimethoxybenzamide …
Matched Salts cas: … 122892-31-3 …

Nafithromycin

Nafithromycin is under investigation in clinical trial NCT02903836 (Phase II Study of Oral Nafithromycin in CABP).
Investigational
Matched Iupac: … -1,3,4-thiadiazol-2-yl]ethoxy]-tetradecahydro-2H-furo[2,3-c]oxacyclotetradecane-3-carboximidamide ... (Z,3R,3aS,4R,6R,8R,9R,10R,12R,15R,15aS)-9-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2- ... yl]oxy}-15-ethyl-8-methoxy-4,6,8,10,12,15a-hexamethyl-2,5,11,13-tetraoxo-N'-[(1S)-1-[5-(pyridin-2-yl) …

Urabrelimab

Investigational

4-Bromo-2,5-dimethoxyamphetamine

Experimental
Illicit
Matched Iupac: … 1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine …

FINLAY-FR-1

FINLAY-FR-1, also known as Soberana 01, is a vaccine candidate for COVID-19 that is being led developmentally by the Finlay Vaccine Institute . It is currently being tested in the clinical trial RPCEC00000332 (Phase I / II, randomized, controlled, adaptive, double-blind and multicenter study to evaluate the safety, reactogenicity and...
Investigational
Matched Synonyms: … FINLAY-FR-1 anti-SARS-CoV-2 vaccine candidate …
Matched Description: … evaluate the safety, reactogenicity and immunogenicity, of the prophylactic FINLAY-FR-1 anti-SARS-CoV-2 …

Calusterone

A 17-alkylated orally active androgenic steroid. A Schedule IV drug in Canada.
Experimental
Illicit
Matched Synonyms: … 17beta-Hydroxy-7beta,17-dimethylandrost-4-en-3-one ... 17-beta-Hydroxy-7-beta,17-alpha-dimethylandrost-4-ene-3-one ... 17beta-Hydroxy-7beta,17alpha-dimethylandrost-4-ene-3-one …

PEGylated Recombinant Factor VIII

PEGylated Recombinant Factor VIII is under investigation in clinical trial NCT02585960 (BAX 855 Pk-guided Dosing).
Investigational

Allogeneic natural killer cells

Investigational

Bifunctional epoxide hydrolase 2

Bifunctional epoxide hydrolase 2 is under investigation in clinical trial NCT00654966 (Evaluation of the Effects of Urotensin-II and Soluble Epoxide Hydrolase Inhibitors on Skin Microvessel Tone in Patients With Heart Failure, and in Healthy Volunteers).
Investigational
Matched Name: … Bifunctional epoxide hydrolase 2 …
Matched Description: … Bifunctional epoxide hydrolase 2 is under investigation in clinical trial NCT00654966 (Evaluation of …

2,5-Dimethoxy-4-ethylamphetamine

Experimental
Illicit
Matched Iupac: … 1-(4-ethyl-2,5-dimethoxyphenyl)propan-2-amine …

Binodenoson

Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A2A receptor. This specificity allows Binodenoson to deliver - in a single injection - a more effective dose of medication with fewer side effects than current treatments, which typically require a...
Investigational
Matched Synonyms: … 2-((Cyclohexylmethylene)hydrazino)adenosine …
Matched Iupac: … (2R,3R,4S,5R)-2-{6-amino-2-[(2E)-2-(cyclohexylmethylidene)hydrazin-1-yl]-9H-purin-9-yl}-5-(hydroxymethyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Immucin

Investigational

Oleoyl-estrone

Oleoyl-estrone (OE) is a fatty acid ester of estrone. This hormone occurs naturally and is found circulating in various animal species and humans. It has been shown in animal studies to promote the loss of body fat while maintaining body protein storage, maintaining nitrogen balance. Body protein loss is an...
Investigational
Matched Synonyms: … Estrone 3-oleate …

Rifalazil

Rifalazil is a derivative of the antibiotic rifamycin. It is being investigated by ActivBiotics for the treatment of various bacterial infections.
Investigational
Matched Synonyms: … 3'-hydroxy-5'-(4-isobutyl-1-piperazinyl)benzoxazinorifamycin …
Matched Iupac: … 14R,15R,16R,17S,18S,19E,21Z)-2,15,17,32-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-30-[4-(2- …

3,4-Methylenedioxy-N-isopropylamphetamine

MDI-P has demonstrated potent anti-HIV activity. MDI-P has been shown to be effective in killing HIV in cell culture. HIV is the virus that causes acquired immune deficiency syndrome (AIDS). MDI-P is also a potential therapeutic agent for the treatment of the symptoms of cystic fibrosis ("CF").
Investigational
Matched Iupac: … [1-(2H-1,3-benzodioxol-5-yl)propan-2-yl](propan-2-yl)amine …

Glyceraldehyde-3-Phosphate Dehydrogenase

Investigational
Matched Name: … Glyceraldehyde-3-Phosphate Dehydrogenase …
Matched Categories: … Glyceraldehyde-3-Phosphate Dehydrogenases, antagonists & inhibitors …

INM004

INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being investigated to treat Shiga-toxin producing bacterial infection relating to the prevention of hemolytic uremic syndrome.
Investigational
Matched Synonyms: … Anti-Shiga toxin hyperimmune equine immunoglobulin F(ab')2 fragment ... Neutralizing equine anti-Stx hyperimmune immunoglobulin F(ab')2 fragment …
Matched Description: … INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being …

Tesmilifene

Tesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast cancer.
Investigational
Matched Synonyms: … N,N-diethyl-2-((4-phenylmethyl)phenoxy)ethanamine …
Matched Iupac: … [2-(4-benzylphenoxy)ethyl]diethylamine …

CTx-PDE6b

CTx-PDE6b is an adeno-associated virus (AAV) based gene therapy designed to deliver a full-length non-mutated copy of the functional human PDE6b gene. Being commercialied by Coave Therapeutics, it is being investigated for the treatment of retinitis pigmentosa due to PDE6b gene mutations.
Investigational

Sevirumab

Investigational

1-Testosterone

1-Testosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead of 4,5-double bond in its A ring.
Experimental
Illicit
Investigational
Matched Synonyms: … 17beta-hydroxy-5alpha-androst-1-en-3-one …

Tenamfetamine

An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally. [PubChem]
Experimental
Illicit
Matched Iupac: … 1-(2H-1,3-benzodioxol-5-yl)propan-2-amine …

Dimetacrine

Dimetacrine is also known as dimethacrine or acripamine. It is marketed under the names Istonil, Istonyl, Linostil, and Miroistonil. Dimetacrine is a tricyclic antidepressant (TCA) with imipramine-like effects used in Europe for the treatment of depression. Dimetacrine is no longer used in Japan.
Experimental
Withdrawn
Matched Synonyms: … 3-(9,9-dimethylacridin-10-yl)-N,N-dimethyl-propan-1-amine …
Matched Iupac: … [3-(9,9-dimethyl-9,10-dihydroacridin-10-yl)propyl]dimethylamine …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Displaying drugs 3501 - 3525 of 3718 in total