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Displaying drugs 576 - 600 of 773 in total
Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Investigational
Matched Synonyms: … DNA (recombinant human telomerase-specific replication-competent oncolytic adenovirus 5 vector OBP-301 …
Experimental
Matched Synonyms: … Cinnamomum cassia stem bark …
Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … DNA (RECOMBINANT LENTIVIRUS VECTOR INXN-2004-TRANSDUCED HUMAN AUTOLOGOUS DYSTROPHIC EPIDERMOLYSIS BULLOSA …
Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … DNA, D(P-THIO)(C-T-A-T-C-T-RGM-RUM-M5C-C7G-T-T-C-T-C-T-RGM-RUM) …
Olezarsen is an antisense oligonucleotide targeting messenger RNA for apolipoprotein C-III (APOC3).
Investigational
Matched Synonyms: … DNA, D(P-THIO)((2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O- …
Ginseng is promoted as an adaptogen (a product that increases the body's resistance to stress), one which can to a certain extent be supported with reference to its anticarcinogenic and antioxidant properties. Ginseng is also known to contain phytoestrogens.
Investigational
Nutraceutical
Matched Products: … Stem Cell Extract of wild mountain ginseng …
Camptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Experimental
Matched Description: … This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. ... Camptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata …
Investigational
Matched Categories: … DNA-Directed DNA Polymerase ... DNA Nucleotidyltransferases ... RNA-Directed DNA Polymerase …
Experimental
Matched Categories: … DNA-Directed RNA Polymerases, antagonists & inhibitors …
Deoxyribonuclease I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7 . It is normally found in saliva, urine, pancreatic secretions, and blood . Because of the hypothesis that increased concentrations of high-molecular-weight DNA is a factor for airway obstruction, abnormal viscoelastic properties of the sputum,...
Investigational
Matched Description: … Because of the hypothesis that increased concentrations of high-molecular-weight DNA is a factor for …
Investigational
Lersivirine has been used in trials studying the treatment of HIV-1.
Investigational
Matched Categories: … RNA-Directed DNA Polymerase …
NSI-566 is a stem cell therapy consisting of human spinal cord-derived neural stem cells. Developed by Seneca Biopharma, it is being investigated for the treatment of amyotrophic lateral sclerosis (ALS), stroke, and chronic spinal cord injury (cSCI).
Investigational
Matched Description: … NSI-566 is a stem cell therapy consisting of human spinal cord-derived neural stem cells. …
Dilanubicel consists of ex vivo expanded hematopoietic stem and progenitor cells.
Investigational
Matched Description: … Dilanubicel consists of ex vivo expanded hematopoietic stem and progenitor cells. …
Amuvatinib has been used in trials studying the treatment of Solid Tumors and Small Cell Lung Carcinoma. Amuvatinib is an oral, selective multi-targeted tyrosine kinase inhibitor that suppresses c-MET, c-RET and the mutant forms of c-KIT, PDGFR and FLT3. Amuvatinib also suppresses Rad51 protein, a critical component of double-stranded DNA...
Investigational
Matched Description: … Amuvatinib also suppresses Rad51 protein, a critical component of double-stranded DNA repair in cancer …
ASP-7317 consists of human embryonic stem cell-derived retinal pigment epithelium cells.
Investigational
Matched Description: … ASP-7317 consists of human embryonic stem cell-derived retinal pigment epithelium cells. …
GIVI-MPC is a therapy that uses human-induced pluripotent stem cell-derived myogenic progenitor cells.
Investigational
Matched Description: … GIVI-MPC is a therapy that uses human-induced pluripotent stem cell-derived myogenic progenitor cells …
TBX-1400 consists of human donor hematopoietic stem and progenitor cells.
Investigational
Matched Description: … TBX-1400 consists of human donor hematopoietic stem and progenitor cells. …
OSSM-007 consists of interferon-gamma primed allogeneic mesenchymal stem cells.
Investigational
Matched Description: … OSSM-007 consists of interferon-gamma primed allogeneic mesenchymal stem cells. …
Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis).
Investigational
Matched Categories: … DNA-Binding Proteins …
Olaptesed Pegol has been investigated for the treatment of Hematopoietic Stem Cell Transplantation.
Investigational
Matched Description: … Olaptesed Pegol has been investigated for the treatment of Hematopoietic Stem Cell Transplantation. …
MDR-101 is a CD34+ hematopoietic stem and progenitor cells with CD3+ T-cells
Investigational
Matched Description: … MDR-101 is a CD34+ hematopoietic stem and progenitor cells with CD3+ T-cells …
Tallimustine, a benzoyl mustard derivative of distamycin A, is an alkylating agent that binds to the minor groove of DNA.[A182036,A182039] It's association with severe myelotoxicity lead to the end of its development in favour of α-halogenoacrylamide derivatives such as brostallicin, which have a favourable cytotoxicity/myelotoxicity ratio.[A182039,A182045] Newer generations of DNA...
Experimental
Matched Description: … benzoyl mustard derivative of distamycin A, is an alkylating agent that binds to the minor groove of DNA ... [A182039,A182045] Newer generations of DNA minor groove binding agents can more specifically recognize …
OTL-201 is an investigational hematopoietic stem cell (HSC) gene therapy being developed by Orchard Therapeutics for the treatment of mucopolysaccharidosis type IIIA (MPS-IIIA). It consists of a lentiviral vector to insert a functional copy of the human N-Sulfoglucosamine Sulfohydrolase (SGSH) gene into autologous CD34+ hematopoietic stem cells.
Investigational
Matched Description: … OTL-201 is an investigational hematopoietic stem cell (HSC) gene therapy being developed by Orchard Therapeutics ... copy of the human N-Sulfoglucosamine Sulfohydrolase (SGSH) gene into autologous CD34+ hematopoietic stem
Investigational
Matched Categories: … DNA-Binding Proteins …
Displaying drugs 576 - 600 of 773 in total