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Displaying drugs 951 - 975 of 1064 in total
LR-103 is a naturally occurring D-hormone that is produced by the kidneys from vitamin D. LR-103 is one of the D-hormones produced from Hectorol. It is developed for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD). Studies have shown LR-103 has the same potency as calcitriol,...
Investigational
Calcitonin is a polypeptide hormone secreted by the parafollicular cells of the thyroid gland in mammals. It inhibits bone resorption and lowers both serum and urinary calcium concentrations. Human calcitonin is available only in very small quantities but has been used in some studies. The first commercially available preparation in...
Experimental
Matched Description: … It inhibits bone resorption and lowers both serum and urinary calcium concentrations. …
Matched Categories: … Calcium Homeostasis …
Experimental
Matched Salts name: … Tuaminoheptane sulfate
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Quisqualic acid is an agonist at two subsets of excitatory amino acid receptors, ionotropic receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores. The compound is obtained from the seeds and fruit of Quisqualis chinensis.
Experimental
Matched Description: … receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium
Experimental
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Experimental
Hexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent.
Experimental
Withdrawn
Matched Salts name: … Hexoprenaline sulfate
Experimental
Matched Categories: … Calcium-Transporting ATPases, antagonists & inhibitors …
Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies. In contrast with other xanthine derivatives, doxofylline does...
Experimental
Matched Description: … Unlike theophylline, doxofylline does not affect calcium influx and does not antagonize the actions of ... calcium channel blockers which could explain reduced cardiac adverse reactions associated with the drug …
Aranidipine is a novel dihydropyridine derivative that gives rise to two active metabolites (M-1α and M-1β) that exhibit hypotensive activity. It is a calcium antagonist with the formula methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate. It was developed by Maruko Seiyaku, introduced by Taiho and launched in Japan in 1997.
Experimental
Matched Description: … It is a calcium antagonist with the formula methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl …
Matched Categories: … Calcium Channel Blockers …
Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression of the pain reflex. It is not approved for use in the United States, but is available in other countries...
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Experimental
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Experimental
Matched Categories: … Calcium-Transporting ATPases, antagonists & inhibitors …
BRX-235 (iroxanadine) is a a novel small molecule synthesized by Biorex, Hungary that acts as a cardioprotective agent. It induces phosphorylation of p38 SAPK, which plays an important role in EC homeostasis. endothelial cell (EC). EC function plays a central role in vascular diseases (e.g. atherosclerosis, restenosis, diabetic angiopathies, microvascular...
Investigational
Matched Description: … BRX-235 also causes translocation of calcium-dependent protein kinase C isoform to membranes. …
Experimental
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Tolperisone is an oral, centrally acting muscle relaxant. Its precise mechanism is not completely understood, though it blocks sodium and calcium channels. It possesses a high affinity for nervous system tissue, reaching highest concentrations in brain stem, spinal cord and peripheral nerves. Based on existing clinical data, Tolperisone is not...
Investigational
Matched Description: … Its precise mechanism is not completely understood, though it blocks sodium and calcium channels. …
Naftopidil has been investigated for the treatment of Disorder of Urinary Stent.
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Experimental
Matched Salts name: … Amfenac sodium anhydrous
PD-98059 is an inhibitor of MAP-kinase kinase activation.
Investigational
Matched Categories: … Calcium-Calmodulin-Dependent Protein Kinases, antagonists & inhibitors …
Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.
Investigational
Matched Categories: … Calcium-Calmodulin-Dependent Protein Kinases, antagonists & inhibitors …
Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. In 1982, it was approved in Japan and South Korea for the management of bronchial asthma. Indications for keloid and hypertrophic scar were added in 1993. It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis...
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Morniflumate is a non-steroidal anti-inflammatory drug with antipyretic properties. It is the morpholinoethyl ester of niflumic acid . In one study, post morniflumate ingestion, physical examination and clinical symptoms of those with bronchitis showed improvement .
Experimental
Experimental
Investigational
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents …
Investigational
Matched Categories: … Calcium-Regulating Hormones and Agents …
Displaying drugs 951 - 975 of 1064 in total