Identification

Name
Eperisone
Accession Number
DB08992
Type
Small Molecule
Groups
Approved, Investigational
Description

Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression of the pain reflex. It is not approved for use in the United States, but is available in other countries like India, South Korea, and Bangladesh.

Structure
Thumb
Synonyms
  • (2RS)-1-(4-ethylphenyl)-2-methyl-3-(1-piperidyl)propan-1-one
  • Eperison
  • Eperisona
  • Epérisone
  • Eperisonum
External IDs
EMPP
Product Ingredients
IngredientUNIICASInChI Key
Eperisone hydrochlorideU38O8U7P6X56839-43-1GTAXGNCCEYZRII-UHFFFAOYSA-N
International/Other Brands
Akitonal (Choseido Pharmaceutical) / Elexin (South Korea) / Myonal (Eisai) / Myoperison (Kobayashi Kako) / Rapisone (Abbott)
Categories
UNII
2M2P0551D3
CAS number
64840-90-0
Weight
Average: 259.3865
Monoisotopic: 259.193614427
Chemical Formula
C17H25NO
InChI Key
SQUNAWUMZGQQJD-UHFFFAOYSA-N
InChI
InChI=1S/C17H25NO/c1-3-15-7-9-16(10-8-15)17(19)14(2)13-18-11-5-4-6-12-18/h7-10,14H,3-6,11-13H2,1-2H3
IUPAC Name
1-(4-ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one
SMILES
CCC1=CC=C(C=C1)C(=O)C(C)CN1CCCCC1

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteractionDrug group
2,5-Dimethoxy-4-ethylthioamphetamineThe risk or severity of adverse effects can be increased when Eperisone is combined with 2,5-Dimethoxy-4-ethylthioamphetamine.Experimental
3,4-MethylenedioxyamphetamineThe risk or severity of adverse effects can be increased when 3,4-Methylenedioxyamphetamine is combined with Eperisone.Experimental, Illicit
4-Bromo-2,5-dimethoxyamphetamineThe risk or severity of adverse effects can be increased when 4-Bromo-2,5-dimethoxyamphetamine is combined with Eperisone.Experimental, Illicit
4-MethoxyamphetamineThe risk or severity of adverse effects can be increased when 4-Methoxyamphetamine is combined with Eperisone.Experimental, Illicit
5-methoxy-N,N-dimethyltryptamineThe risk or severity of adverse effects can be increased when Eperisone is combined with 5-methoxy-N,N-dimethyltryptamine.Experimental, Illicit
7-NitroindazoleThe risk or severity of adverse effects can be increased when 7-Nitroindazole is combined with Eperisone.Experimental
7,8-Dichloro-1,2,3,4-tetrahydroisoquinolineThe risk or severity of adverse effects can be increased when 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline is combined with Eperisone.Experimental
AbafunginThe therapeutic efficacy of Abafungin can be increased when used in combination with Eperisone.Investigational
AcepromazineThe risk or severity of hypotension can be increased when Acepromazine is combined with Eperisone.Approved, Vet Approved
AceprometazineThe risk or severity of adverse effects can be increased when Aceprometazine is combined with Eperisone.Approved
AcetazolamideThe risk or severity of adverse effects can be increased when Acetazolamide is combined with Eperisone.Approved, Vet Approved
AcetophenazineThe risk or severity of adverse effects can be increased when Eperisone is combined with Acetophenazine.Approved
Acetylglycinamide chloral hydrateThe risk or severity of adverse effects can be increased when Acetylglycinamide chloral hydrate is combined with Eperisone.Experimental
AdinazolamThe risk or severity of adverse effects can be increased when Adinazolam is combined with Eperisone.Approved
AdipiplonThe risk or severity of adverse effects can be increased when Adipiplon is combined with Eperisone.Investigational
AgomelatineThe risk or severity of adverse effects can be increased when Agomelatine is combined with Eperisone.Approved, Investigational
AlaproclateThe risk or severity of adverse effects can be increased when Eperisone is combined with Alaproclate.Experimental
AlbaconazoleThe therapeutic efficacy of Albaconazole can be increased when used in combination with Eperisone.Investigational
AlcuroniumEperisone may increase the neuromuscular blocking activities of Alcuronium.Experimental
AlfaxaloneThe risk or severity of adverse effects can be increased when Alfaxalone is combined with Eperisone.Vet Approved
AlfentanilThe risk or severity of adverse effects can be increased when Alfentanil is combined with Eperisone.Approved, Illicit
AlfuzosinThe risk or severity of hypotension can be increased when Alfuzosin is combined with Eperisone.Approved, Investigational
AlimemazineThe risk or severity of adverse effects can be increased when Eperisone is combined with Alimemazine.Approved, Vet Approved
AllobarbitalThe risk or severity of adverse effects can be increased when Allobarbital is combined with Eperisone.Experimental
AllopregnanoloneThe risk or severity of adverse effects can be increased when Allopregnanolone is combined with Eperisone.Investigational
AlmotriptanThe risk or severity of adverse effects can be increased when Eperisone is combined with Almotriptan.Approved, Investigational
AlosetronThe risk or severity of adverse effects can be increased when Eperisone is combined with Alosetron.Approved, Withdrawn
AlphacetylmethadolThe risk or severity of adverse effects can be increased when Alphacetylmethadol is combined with Eperisone.Experimental, Illicit
AlphaprodineThe risk or severity of adverse effects can be increased when Alphaprodine is combined with Eperisone.Illicit
AlprazolamThe risk or severity of adverse effects can be increased when Alprazolam is combined with Eperisone.Approved, Illicit, Investigational
AlprenololThe risk or severity of adverse effects can be increased when Eperisone is combined with Alprenolol.Approved, Withdrawn
AlverineThe risk or severity of adverse effects can be increased when Eperisone is combined with Alverine.Approved, Investigational
AmikacinThe risk or severity of adverse effects can be increased when Eperisone is combined with Amikacin.Approved, Investigational, Vet Approved
AmineptineThe risk or severity of adverse effects can be increased when Amineptine is combined with Eperisone.Illicit, Withdrawn
AmiodaroneThe metabolism of Eperisone can be decreased when combined with Amiodarone.Approved, Investigational
AmisulprideThe risk or severity of adverse effects can be increased when Amisulpride is combined with Eperisone.Approved, Investigational
AmitriptylineThe risk or severity of hypotension can be increased when Amitriptyline is combined with Eperisone.Approved
AmitriptylinoxideThe risk or severity of adverse effects can be increased when Amitriptylinoxide is combined with Eperisone.Approved, Investigational
AmobarbitalThe metabolism of Eperisone can be increased when combined with Amobarbital.Approved, Illicit
AmoxapineThe risk or severity of hypotension can be increased when Amoxapine is combined with Eperisone.Approved
AmperozideThe risk or severity of adverse effects can be increased when Amperozide is combined with Eperisone.Experimental
AmphetamineThe risk or severity of adverse effects can be increased when Amphetamine is combined with Eperisone.Approved, Illicit, Investigational
Amphotericin BEperisone may decrease the nephrotoxic activities of Amphotericin B.Approved, Investigational
AmprenavirThe metabolism of Eperisone can be decreased when combined with Amprenavir.Approved, Investigational
AniracetamThe risk or severity of adverse effects can be increased when Aniracetam is combined with Eperisone.Experimental
ApalutamideThe serum concentration of Eperisone can be decreased when it is combined with Apalutamide.Approved, Investigational
APD791The risk or severity of adverse effects can be increased when Eperisone is combined with APD791.Investigational
ApomorphineThe risk or severity of adverse effects can be increased when Eperisone is combined with Apomorphine.Approved, Investigational
ApramycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Apramycin.Experimental, Vet Approved
AprepitantThe serum concentration of Eperisone can be increased when it is combined with Aprepitant.Approved, Investigational
AprobarbitalThe risk or severity of adverse effects can be increased when Aprobarbital is combined with Eperisone.Approved, Illicit
ApronalideThe risk or severity of adverse effects can be increased when Apronalide is combined with Eperisone.Experimental
Arbaclofen PlacarbilThe risk or severity of adverse effects can be increased when Eperisone is combined with Arbaclofen Placarbil.Investigational
ArbekacinThe risk or severity of adverse effects can be increased when Eperisone is combined with Arbekacin.Approved, Investigational
AripiprazoleThe risk or severity of hypotension can be increased when Aripiprazole is combined with Eperisone.Approved, Investigational
Aripiprazole lauroxilThe risk or severity of hypotension can be increased when Aripiprazole lauroxil is combined with Eperisone.Approved, Investigational
ArotinololThe risk or severity of hypotension can be increased when Arotinolol is combined with Eperisone.Investigational
AsenapineThe risk or severity of hypotension can be increased when Asenapine is combined with Eperisone.Approved
AtazanavirThe metabolism of Eperisone can be decreased when combined with Atazanavir.Approved, Investigational
AtomoxetineThe risk or severity of adverse effects can be increased when Atomoxetine is combined with Eperisone.Approved
AtracuriumEperisone may increase the neuromuscular blocking activities of Atracurium.Approved, Experimental, Investigational
Atracurium besylateEperisone may increase the neuromuscular blocking activities of Atracurium besylate.Approved
AzaperoneThe risk or severity of adverse effects can be increased when Azaperone is combined with Eperisone.Investigational, Vet Approved
AZD-3043The risk or severity of adverse effects can be increased when AZD-3043 is combined with Eperisone.Investigational
AzelastineEperisone may increase the central nervous system depressant (CNS depressant) activities of Azelastine.Approved
BaclofenThe risk or severity of adverse effects can be increased when Baclofen is combined with Eperisone.Approved
BarbexacloneThe metabolism of Eperisone can be increased when combined with Barbexaclone.Experimental
BarbitalThe metabolism of Eperisone can be increased when combined with Barbital.Illicit
BeclamideThe risk or severity of adverse effects can be increased when Eperisone is combined with Beclamide.Experimental
BekanamycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Bekanamycin.Experimental
BenactyzineThe risk or severity of adverse effects can be increased when Benactyzine is combined with Eperisone.Withdrawn
BenmoxinThe risk or severity of adverse effects can be increased when Benmoxin is combined with Eperisone.Withdrawn
BenperidolThe risk or severity of adverse effects can be increased when Benperidol is combined with Eperisone.Approved, Investigational
BenzoctamineThe risk or severity of adverse effects can be increased when Benzoctamine is combined with Eperisone.Approved
BenzphetamineThe risk or severity of adverse effects can be increased when Benzphetamine is combined with Eperisone.Approved, Illicit
Benzyl alcoholThe risk or severity of adverse effects can be increased when Benzyl alcohol is combined with Eperisone.Approved
BevantololThe risk or severity of hypotension can be increased when Bevantolol is combined with Eperisone.Approved
BifemelaneThe risk or severity of adverse effects can be increased when Bifemelane is combined with Eperisone.Experimental
BifeprunoxThe risk or severity of adverse effects can be increased when Eperisone is combined with Bifeprunox.Investigational
BifonazoleThe therapeutic efficacy of Bifonazole can be increased when used in combination with Eperisone.Approved, Investigational
BisacodylThe therapeutic efficacy of Bisacodyl can be decreased when used in combination with Eperisone.Approved
BisoxatinThe therapeutic efficacy of Bisoxatin can be decreased when used in combination with Eperisone.Approved
BL-1020The risk or severity of adverse effects can be increased when Eperisone is combined with BL-1020.Investigational
BlonanserinThe risk or severity of adverse effects can be increased when Eperisone is combined with Blonanserin.Approved, Investigational
BoceprevirThe metabolism of Eperisone can be decreased when combined with Boceprevir.Approved, Withdrawn
BosentanThe serum concentration of Eperisone can be decreased when it is combined with Bosentan.Approved, Investigational
Botulinum Toxin Type AThe risk or severity of adverse effects can be increased when Eperisone is combined with Botulinum Toxin Type A.Approved, Investigational
Botulinum Toxin Type BThe risk or severity of adverse effects can be increased when Eperisone is combined with Botulinum Toxin Type B.Approved, Investigational
BrexpiprazoleThe risk or severity of hypotension can be increased when Brexpiprazole is combined with Eperisone.Approved, Investigational
BrimonidineBrimonidine may increase the central nervous system depressant (CNS depressant) activities of Eperisone.Approved
BrivaracetamThe risk or severity of adverse effects can be increased when Eperisone is combined with Brivaracetam.Approved, Investigational
BrofaromineThe risk or severity of adverse effects can be increased when Brofaromine is combined with Eperisone.Experimental
BromazepamThe risk or severity of adverse effects can be increased when Bromazepam is combined with Eperisone.Approved, Illicit, Investigational
BromisovalThe risk or severity of adverse effects can be increased when Bromisoval is combined with Eperisone.Experimental
BromocriptineThe risk or severity of hypotension can be increased when Bromocriptine is combined with Eperisone.Approved, Investigational
BromperidolThe risk or severity of adverse effects can be increased when Bromperidol is combined with Eperisone.Approved, Investigational
BrompheniramineThe risk or severity of adverse effects can be increased when Brompheniramine is combined with Eperisone.Approved
BrotizolamThe risk or severity of adverse effects can be increased when Brotizolam is combined with Eperisone.Approved, Investigational, Withdrawn
BucindololThe risk or severity of hypotension can be increased when Bucindolol is combined with Eperisone.Investigational
BufotenineThe risk or severity of adverse effects can be increased when Bufotenine is combined with Eperisone.Experimental, Illicit
BunazosinThe risk or severity of hypotension can be increased when Bunazosin is combined with Eperisone.Investigational
BuprenorphineEperisone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.Approved, Illicit, Investigational, Vet Approved
BupropionThe risk or severity of adverse effects can be increased when Bupropion is combined with Eperisone.Approved
BuspironeThe risk or severity of adverse effects can be increased when Buspirone is combined with Eperisone.Approved, Investigational
ButabarbitalThe risk or severity of adverse effects can be increased when Butabarbital is combined with Eperisone.Approved, Illicit
ButalbitalThe risk or severity of adverse effects can be increased when Butalbital is combined with Eperisone.Approved, Illicit
ButaperazineThe risk or severity of adverse effects can be increased when Eperisone is combined with Butaperazine.Experimental
ButethalThe risk or severity of adverse effects can be increased when Butethal is combined with Eperisone.Approved, Illicit
ButoconazoleThe therapeutic efficacy of Butoconazole can be increased when used in combination with Eperisone.Approved
ButorphanolThe risk or severity of adverse effects can be increased when Butorphanol is combined with Eperisone.Approved, Illicit, Vet Approved
ButriptylineThe risk or severity of adverse effects can be increased when Butriptyline is combined with Eperisone.Approved
CabergolineThe risk or severity of adverse effects can be increased when Eperisone is combined with Cabergoline.Approved
Calcium AcetateThe therapeutic efficacy of Eperisone can be decreased when used in combination with Calcium Acetate.Approved, Investigational
Calcium CarbonateThe therapeutic efficacy of Eperisone can be decreased when used in combination with Calcium Carbonate.Approved, Investigational
Calcium ChlorideThe therapeutic efficacy of Eperisone can be decreased when used in combination with Calcium Chloride.Approved
Calcium CitrateThe therapeutic efficacy of Eperisone can be decreased when used in combination with Calcium Citrate.Approved
Calcium glubionateThe therapeutic efficacy of Eperisone can be decreased when used in combination with Calcium glubionate.Approved
Calcium GluceptateThe therapeutic efficacy of Eperisone can be decreased when used in combination with Calcium Gluceptate.Approved
Calcium gluconateThe therapeutic efficacy of Eperisone can be decreased when used in combination with Calcium gluconate.Approved, Vet Approved
Calcium lactateThe therapeutic efficacy of Eperisone can be decreased when used in combination with Calcium lactate.Approved, Investigational, Vet Approved
Calcium lactate gluconateThe therapeutic efficacy of Eperisone can be decreased when used in combination with Calcium lactate gluconate.Experimental
Calcium levulinateThe therapeutic efficacy of Eperisone can be decreased when used in combination with Calcium levulinate.Approved, Experimental
Calcium pangamateThe therapeutic efficacy of Eperisone can be decreased when used in combination with Calcium pangamate.Experimental
Calcium PhosphateThe therapeutic efficacy of Eperisone can be decreased when used in combination with Calcium Phosphate.Approved
CamazepamThe risk or severity of adverse effects can be increased when Camazepam is combined with Eperisone.Approved, Illicit
CannabidiolThe risk or severity of adverse effects can be increased when Eperisone is combined with Cannabidiol.Approved, Investigational
CannabidivarinThe risk or severity of adverse effects can be increased when Eperisone is combined with Cannabidivarin.Investigational
CapreomycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Capreomycin.Approved
CaptodiameThe risk or severity of adverse effects can be increased when Captodiame is combined with Eperisone.Approved, Investigational
CarbamazepineThe metabolism of Eperisone can be increased when combined with Carbamazepine.Approved, Investigational
CarbinoxamineThe risk or severity of adverse effects can be increased when Carbinoxamine is combined with Eperisone.Approved
CarboxymethylcelluloseThe therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Eperisone.Approved, Investigational
CarbromalThe risk or severity of adverse effects can be increased when Carbromal is combined with Eperisone.Experimental
CarfentanilThe risk or severity of adverse effects can be increased when Carfentanil is combined with Eperisone.Illicit, Investigational, Vet Approved
CariprazineThe risk or severity of adverse effects can be increased when Eperisone is combined with Cariprazine.Approved, Investigational
CarisbamateThe risk or severity of adverse effects can be increased when Eperisone is combined with Carisbamate.Investigational
CarisoprodolThe risk or severity of adverse effects can be increased when Carisoprodol is combined with Eperisone.Approved
CaroxazoneThe risk or severity of adverse effects can be increased when Caroxazone is combined with Eperisone.Withdrawn
CarvedilolThe risk or severity of hypotension can be increased when Carvedilol is combined with Eperisone.Approved, Investigational
Castor oilThe therapeutic efficacy of Castor oil can be decreased when used in combination with Eperisone.Approved, Investigational, Nutraceutical, Vet Approved
CathinoneThe risk or severity of adverse effects can be increased when Cathinone is combined with Eperisone.Illicit
CeritinibThe serum concentration of Eperisone can be increased when it is combined with Ceritinib.Approved
CerlapirdineThe risk or severity of adverse effects can be increased when Eperisone is combined with Cerlapirdine.Investigational
CetirizineThe risk or severity of adverse effects can be increased when Cetirizine is combined with Eperisone.Approved
Chloral hydrateThe risk or severity of adverse effects can be increased when Chloral hydrate is combined with Eperisone.Approved, Illicit, Investigational, Vet Approved
ChlordiazepoxideThe risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Eperisone.Approved, Illicit, Investigational
ChlormezanoneThe risk or severity of adverse effects can be increased when Chlormezanone is combined with Eperisone.Approved, Investigational, Withdrawn
ChloroquineThe risk or severity of adverse effects can be increased when Eperisone is combined with Chloroquine.Approved, Investigational, Vet Approved
ChlorphenamineThe risk or severity of adverse effects can be increased when Chlorphenamine is combined with Eperisone.Approved
ChlorphenesinThe risk or severity of adverse effects can be increased when Eperisone is combined with Chlorphenesin.Approved, Vet Approved, Withdrawn
ChlorproethazineThe risk or severity of adverse effects can be increased when Eperisone is combined with Chlorproethazine.Experimental
ChlorpromazineThe risk or severity of hypotension can be increased when Chlorpromazine is combined with Eperisone.Approved, Investigational, Vet Approved
ChlorprothixeneThe risk or severity of adverse effects can be increased when Chlorprothixene is combined with Eperisone.Approved, Investigational, Withdrawn
ChlortetracyclineThe risk or severity of adverse effects can be increased when Eperisone is combined with Chlortetracycline.Approved, Investigational, Vet Approved
ChlorzoxazoneThe risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Eperisone.Approved
CilansetronThe risk or severity of adverse effects can be increased when Eperisone is combined with Cilansetron.Investigational
CimetidineThe serum concentration of Eperisone can be increased when it is combined with Cimetidine.Approved, Investigational
CinitaprideThe risk or severity of adverse effects can be increased when Eperisone is combined with Cinitapride.Approved, Investigational
CinolazepamThe risk or severity of adverse effects can be increased when Cinolazepam is combined with Eperisone.Approved
CisaprideThe risk or severity of adverse effects can be increased when Eperisone is combined with Cisapride.Approved, Investigational, Withdrawn
CisatracuriumEperisone may increase the neuromuscular blocking activities of Cisatracurium.Approved
CitalopramThe risk or severity of adverse effects can be increased when Eperisone is combined with Citalopram.Approved
ClarithromycinThe metabolism of Eperisone can be decreased when combined with Clarithromycin.Approved
ClemastineThe risk or severity of adverse effects can be increased when Clemastine is combined with Eperisone.Approved, Investigational
ClidiniumThe risk or severity of adverse effects can be increased when Clidinium is combined with Eperisone.Approved
ClindamycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Clindamycin.Approved, Vet Approved
ClobazamThe risk or severity of adverse effects can be increased when Clobazam is combined with Eperisone.Approved, Illicit
clomethiazoleThe risk or severity of adverse effects can be increased when clomethiazole is combined with Eperisone.Investigational
ClomipramineThe risk or severity of adverse effects can be increased when Clomipramine is combined with Eperisone.Approved, Investigational, Vet Approved
ClomocyclineThe risk or severity of adverse effects can be increased when Eperisone is combined with Clomocycline.Approved
ClonazepamThe risk or severity of adverse effects can be increased when Clonazepam is combined with Eperisone.Approved, Illicit
ClonidineThe risk or severity of adverse effects can be increased when Clonidine is combined with Eperisone.Approved
ClopenthixolThe risk or severity of adverse effects can be increased when Clopenthixol is combined with Eperisone.Experimental
ClopidogrelThe therapeutic efficacy of Clopidogrel can be decreased when used in combination with Eperisone.Approved
ClorazepateThe risk or severity of adverse effects can be increased when Clorazepate is combined with Eperisone.Approved, Illicit
ClothiapineThe risk or severity of adverse effects can be increased when Clothiapine is combined with Eperisone.Experimental
ClotiazepamThe risk or severity of adverse effects can be increased when Clotiazepam is combined with Eperisone.Approved, Illicit
ClotrimazoleThe metabolism of Eperisone can be decreased when combined with Clotrimazole.Approved, Vet Approved
CloxazolamThe risk or severity of adverse effects can be increased when Cloxazolam is combined with Eperisone.Approved, Investigational
ClozapineThe risk or severity of hypotension can be increased when Clozapine is combined with Eperisone.Approved
CobicistatThe metabolism of Eperisone can be decreased when combined with Cobicistat.Approved
CodeineThe risk or severity of adverse effects can be increased when Codeine is combined with Eperisone.Approved, Illicit
ColistimethateThe risk or severity of adverse effects can be increased when Eperisone is combined with Colistimethate.Approved, Vet Approved
ColistinThe risk or severity of adverse effects can be increased when Eperisone is combined with Colistin.Approved
ConivaptanThe serum concentration of Conivaptan can be increased when it is combined with Eperisone.Approved, Investigational
CrizotinibThe metabolism of Eperisone can be decreased when combined with Crizotinib.Approved
CurcuminThe metabolism of Eperisone can be decreased when combined with Curcumin.Approved, Investigational
CyamemazineThe risk or severity of adverse effects can be increased when Cyamemazine is combined with Eperisone.Approved
CyclizineThe risk or severity of adverse effects can be increased when Cyclizine is combined with Eperisone.Approved
CyclobarbitalThe risk or severity of adverse effects can be increased when Cyclobarbital is combined with Eperisone.Experimental
CyclobenzaprineThe risk or severity of adverse effects can be increased when Cyclobenzaprine is combined with Eperisone.Approved
CyclopropaneThe risk or severity of adverse effects can be increased when Cyclopropane is combined with Eperisone.Experimental
CyclosporineThe risk or severity of adverse effects can be increased when Eperisone is combined with Cyclosporine.Approved, Investigational, Vet Approved
CyproheptadineThe risk or severity of adverse effects can be increased when Cyproheptadine is combined with Eperisone.Approved
DabrafenibThe serum concentration of Eperisone can be decreased when it is combined with Dabrafenib.Approved, Investigational
DanazolThe metabolism of Eperisone can be decreased when combined with Danazol.Approved
DanthronThe therapeutic efficacy of Danthron can be decreased when used in combination with Eperisone.Approved, Investigational, Withdrawn
DantroleneThe risk or severity of adverse effects can be increased when Dantrolene is combined with Eperisone.Approved, Investigational
DapiprazoleThe risk or severity of hypotension can be increased when Dapiprazole is combined with Eperisone.Approved
DapoxetineThe risk or severity of adverse effects can be increased when Eperisone is combined with Dapoxetine.Investigational
DarunavirThe metabolism of Eperisone can be decreased when combined with Darunavir.Approved
DasatinibThe serum concentration of Eperisone can be increased when it is combined with Dasatinib.Approved, Investigational
DeanolThe risk or severity of adverse effects can be increased when Deanol is combined with Eperisone.Experimental
DecamethoniumThe risk or severity of adverse effects can be increased when Eperisone is combined with Decamethonium.Approved
DeferasiroxThe serum concentration of Eperisone can be decreased when it is combined with Deferasirox.Approved, Investigational
DelavirdineThe metabolism of Eperisone can be decreased when combined with Delavirdine.Approved
DelorazepamThe risk or severity of adverse effects can be increased when Delorazepam is combined with Eperisone.Approved, Illicit, Investigational
DemeclocyclineThe risk or severity of adverse effects can be increased when Eperisone is combined with Demeclocycline.Approved
DeramciclaneThe risk or severity of adverse effects can be increased when Deramciclane is combined with Eperisone.Investigational
DesfluraneThe risk or severity of adverse effects can be increased when Desflurane is combined with Eperisone.Approved
DesipramineThe risk or severity of adverse effects can be increased when Desipramine is combined with Eperisone.Approved, Investigational
DesloratadineThe risk or severity of adverse effects can be increased when Desloratadine is combined with Eperisone.Approved, Investigational
DesvenlafaxineThe risk or severity of adverse effects can be increased when Eperisone is combined with Desvenlafaxine.Approved, Investigational
DetomidineThe risk or severity of adverse effects can be increased when Detomidine is combined with Eperisone.Vet Approved
DexamethasoneThe serum concentration of Eperisone can be decreased when it is combined with Dexamethasone.Approved, Investigational, Vet Approved
DexbrompheniramineThe risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Eperisone.Approved
DexmedetomidineThe risk or severity of adverse effects can be increased when Dexmedetomidine is combined with Eperisone.Approved, Vet Approved
DexmethylphenidateThe risk or severity of adverse effects can be increased when Eperisone is combined with Dexmethylphenidate.Approved, Investigational
DextofisopamThe risk or severity of adverse effects can be increased when Dextofisopam is combined with Eperisone.Investigational
DextromethorphanThe risk or severity of adverse effects can be increased when Eperisone is combined with Dextromethorphan.Approved
DextromoramideThe risk or severity of adverse effects can be increased when Dextromoramide is combined with Eperisone.Experimental, Illicit
DextropropoxypheneThe risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with Eperisone.Approved, Illicit, Investigational, Withdrawn
DezocineThe risk or severity of adverse effects can be increased when Dezocine is combined with Eperisone.Approved, Investigational
DiazepamThe risk or severity of adverse effects can be increased when Diazepam is combined with Eperisone.Approved, Illicit, Investigational, Vet Approved
DibekacinThe risk or severity of adverse effects can be increased when Eperisone is combined with Dibekacin.Experimental
DibenzepinThe risk or severity of adverse effects can be increased when Dibenzepin is combined with Eperisone.Experimental
DichloralphenazoneThe risk or severity of adverse effects can be increased when Dichloralphenazone is combined with Eperisone.Approved, Illicit
Diethyl etherThe risk or severity of adverse effects can be increased when Diethyl ether is combined with Eperisone.Experimental
DifenoxinThe risk or severity of adverse effects can be increased when Difenoxin is combined with Eperisone.Approved, Illicit
DihydrocodeineThe risk or severity of adverse effects can be increased when Dihydrocodeine is combined with Eperisone.Approved, Illicit
DihydroergotamineThe risk or severity of hypotension can be increased when Dihydroergotamine is combined with Eperisone.Approved, Investigational
DihydroetorphineThe risk or severity of adverse effects can be increased when Dihydroetorphine is combined with Eperisone.Experimental, Illicit
DihydromorphineThe risk or severity of adverse effects can be increased when Dihydromorphine is combined with Eperisone.Experimental, Illicit
DihydrostreptomycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Dihydrostreptomycin.Investigational, Vet Approved
DiltiazemThe metabolism of Eperisone can be decreased when combined with Diltiazem.Approved, Investigational
DimenhydrinateThe risk or severity of adverse effects can be increased when Dimenhydrinate is combined with Eperisone.Approved
DimetacrineThe risk or severity of adverse effects can be increased when Dimetacrine is combined with Eperisone.Approved, Withdrawn
DimethyltryptamineThe risk or severity of adverse effects can be increased when Dimethyltryptamine is combined with Eperisone.Experimental, Illicit
DiphenhydramineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Eperisone.Approved, Investigational
DiphenoxylateThe risk or severity of adverse effects can be increased when Diphenoxylate is combined with Eperisone.Approved, Illicit
DixyrazineThe risk or severity of adverse effects can be increased when Dixyrazine is combined with Eperisone.Experimental
DocusateThe therapeutic efficacy of Docusate can be decreased when used in combination with Eperisone.Approved
DolasetronThe risk or severity of adverse effects can be increased when Eperisone is combined with Dolasetron.Approved, Investigational
Domoic AcidThe risk or severity of adverse effects can be increased when Eperisone is combined with Domoic Acid.Experimental
DonepezilThe risk or severity of adverse effects can be increased when Eperisone is combined with Donepezil.Approved
DopamineThe risk or severity of adverse effects can be increased when Eperisone is combined with Dopamine.Approved
DoramectinThe risk or severity of adverse effects can be increased when Doramectin is combined with Eperisone.Vet Approved
DosulepinThe risk or severity of adverse effects can be increased when Dosulepin is combined with Eperisone.Approved
DotarizineThe risk or severity of adverse effects can be increased when Eperisone is combined with Dotarizine.Investigational
DoxacuriumEperisone may increase the neuromuscular blocking activities of Doxacurium.Approved
DoxazosinThe risk or severity of hypotension can be increased when Doxazosin is combined with Eperisone.Approved
DoxefazepamThe risk or severity of adverse effects can be increased when Doxefazepam is combined with Eperisone.Experimental
DoxepinThe risk or severity of hypotension can be increased when Doxepin is combined with Eperisone.Approved, Investigational
DoxycyclineThe metabolism of Eperisone can be decreased when combined with Doxycycline.Approved, Investigational, Vet Approved
DoxylamineDoxylamine may increase the central nervous system depressant (CNS depressant) activities of Eperisone.Approved, Vet Approved
DPDPEThe risk or severity of adverse effects can be increased when DPDPE is combined with Eperisone.Experimental
DronabinolDronabinol may increase the central nervous system depressant (CNS depressant) activities of Eperisone.Approved, Illicit
DronedaroneThe risk or severity of hypotension can be increased when Dronedarone is combined with Eperisone.Approved
DroperidolDroperidol may increase the central nervous system depressant (CNS depressant) activities of Eperisone.Approved, Vet Approved
DrotebanolThe risk or severity of adverse effects can be increased when Drotebanol is combined with Eperisone.Experimental, Illicit
DuloxetineThe risk or severity of adverse effects can be increased when Eperisone is combined with Duloxetine.Approved
DyclonineThe risk or severity of adverse effects can be increased when Dyclonine is combined with Eperisone.Approved
EconazoleThe therapeutic efficacy of Econazole can be increased when used in combination with Eperisone.Approved
EcopipamThe risk or severity of adverse effects can be increased when Ecopipam is combined with Eperisone.Investigational
EdivoxetineThe risk or severity of adverse effects can be increased when Edivoxetine is combined with Eperisone.Investigational
EfavirenzThe serum concentration of Eperisone can be decreased when it is combined with Efavirenz.Approved, Investigational
EfinaconazoleThe therapeutic efficacy of Efinaconazole can be increased when used in combination with Eperisone.Approved
EletriptanThe risk or severity of adverse effects can be increased when Eperisone is combined with Eletriptan.Approved, Investigational
EltanoloneThe risk or severity of adverse effects can be increased when Eltanolone is combined with Eperisone.Investigational
EltoprazineThe risk or severity of adverse effects can be increased when Eperisone is combined with Eltoprazine.Investigational
EmeproniumThe risk or severity of adverse effects can be increased when Emepronium is combined with Eperisone.Experimental
EmylcamateThe risk or severity of adverse effects can be increased when Emylcamate is combined with Eperisone.Experimental
EnfluraneThe risk or severity of adverse effects can be increased when Enflurane is combined with Eperisone.Approved, Investigational, Vet Approved
EntacaponeThe risk or severity of adverse effects can be increased when Entacapone is combined with Eperisone.Approved, Investigational
EnzalutamideThe serum concentration of Eperisone can be decreased when it is combined with Enzalutamide.Approved
EpinastineThe risk or severity of adverse effects can be increased when Eperisone is combined with Epinastine.Approved, Investigational
EplivanserinThe risk or severity of adverse effects can be increased when Eperisone is combined with Eplivanserin.Investigational
Ergoloid mesylateThe risk or severity of adverse effects can be increased when Eperisone is combined with Ergoloid mesylate.Approved
ErgonovineThe risk or severity of adverse effects can be increased when Eperisone is combined with Ergonovine.Approved
ErgotamineThe risk or severity of hypotension can be increased when Ergotamine is combined with Eperisone.Approved
ErythromycinThe metabolism of Eperisone can be decreased when combined with Erythromycin.Approved, Investigational, Vet Approved
EscitalopramThe risk or severity of adverse effects can be increased when Eperisone is combined with Escitalopram.Approved, Investigational
Eslicarbazepine acetateThe risk or severity of adverse effects can be increased when Eslicarbazepine acetate is combined with Eperisone.Approved
EsmirtazapineThe risk or severity of adverse effects can be increased when Esmirtazapine is combined with Eperisone.Investigational
EsreboxetineThe risk or severity of adverse effects can be increased when Eperisone is combined with Esreboxetine.Investigational
EstazolamThe risk or severity of adverse effects can be increased when Estazolam is combined with Eperisone.Approved, Illicit
EszopicloneThe risk or severity of adverse effects can be increased when Eszopiclone is combined with Eperisone.Approved, Investigational
Etacrynic acidThe risk or severity of adverse effects can be increased when Eperisone is combined with Etacrynic acid.Approved, Investigational
EthadioneThe risk or severity of adverse effects can be increased when Eperisone is combined with Ethadione.Experimental
EthanolEperisone may increase the central nervous system depressant (CNS depressant) activities of Ethanol.Approved
EthchlorvynolThe risk or severity of adverse effects can be increased when Ethchlorvynol is combined with Eperisone.Approved, Illicit, Withdrawn
EthosuximideThe risk or severity of adverse effects can be increased when Ethosuximide is combined with Eperisone.Approved
EthotoinThe risk or severity of adverse effects can be increased when Ethotoin is combined with Eperisone.Approved
Ethyl carbamateThe risk or severity of adverse effects can be increased when Ethyl carbamate is combined with Eperisone.Withdrawn
Ethyl chlorideThe risk or severity of adverse effects can be increased when Ethyl chloride is combined with Eperisone.Approved, Experimental, Investigational
Ethyl loflazepateThe risk or severity of adverse effects can be increased when Ethyl loflazepate is combined with Eperisone.Approved, Illicit
EthylmorphineThe risk or severity of adverse effects can be increased when Ethylmorphine is combined with Eperisone.Approved, Illicit
EtifoxineThe risk or severity of adverse effects can be increased when Etifoxine is combined with Eperisone.Investigational, Withdrawn
EtiracetamThe risk or severity of adverse effects can be increased when Eperisone is combined with Etiracetam.Investigational
EtizolamThe risk or severity of adverse effects can be increased when Etizolam is combined with Eperisone.Approved
EtomidateThe risk or severity of adverse effects can be increased when Etomidate is combined with Eperisone.Approved
EtoperidoneThe risk or severity of adverse effects can be increased when Etoperidone is combined with Eperisone.Withdrawn
EtorphineThe risk or severity of adverse effects can be increased when Eperisone is combined with Etorphine.Illicit, Vet Approved
EtravirineThe serum concentration of Eperisone can be decreased when it is combined with Etravirine.Approved
EzogabineThe risk or severity of adverse effects can be increased when Ezogabine is combined with Eperisone.Approved, Investigational
FabomotizoleThe risk or severity of adverse effects can be increased when Fabomotizole is combined with Eperisone.Experimental
Fazadinium bromideThe risk or severity of adverse effects can be increased when Eperisone is combined with Fazadinium bromide.Experimental
FebarbamateThe risk or severity of adverse effects can be increased when Eperisone is combined with Febarbamate.Experimental
FelbamateThe risk or severity of adverse effects can be increased when Felbamate is combined with Eperisone.Approved
FencamfamineThe risk or severity of adverse effects can be increased when Fencamfamine is combined with Eperisone.Approved, Illicit, Withdrawn
FenfluramineThe risk or severity of adverse effects can be increased when Eperisone is combined with Fenfluramine.Approved, Illicit, Investigational, Withdrawn
FentanylThe risk or severity of adverse effects can be increased when Fentanyl is combined with Eperisone.Approved, Illicit, Investigational, Vet Approved
FenticonazoleThe therapeutic efficacy of Fenticonazole can be increased when used in combination with Eperisone.Experimental
FenyramidolThe risk or severity of adverse effects can be increased when Eperisone is combined with Fenyramidol.Experimental
FexofenadineThe risk or severity of adverse effects can be increased when Fexofenadine is combined with Eperisone.Approved, Investigational
FlibanserinThe risk or severity of adverse effects can be increased when Flibanserin is combined with Eperisone.Approved, Investigational
FluanisoneThe risk or severity of adverse effects can be increased when Fluanisone is combined with Eperisone.Experimental
FluconazoleThe metabolism of Eperisone can be decreased when combined with Fluconazole.Approved, Investigational
FludiazepamThe risk or severity of adverse effects can be increased when Fludiazepam is combined with Eperisone.Approved, Illicit
FlunarizineThe risk or severity of adverse effects can be increased when Flunarizine is combined with Eperisone.Approved
FlunitrazepamThe risk or severity of adverse effects can be increased when Flunitrazepam is combined with Eperisone.Approved, Illicit
FluoxetineThe risk or severity of adverse effects can be increased when Eperisone is combined with Fluoxetine.Approved, Vet Approved
FlupentixolThe risk or severity of hypotension can be increased when Flupentixol is combined with Eperisone.Approved, Investigational, Withdrawn
FluphenazineThe risk or severity of adverse effects can be increased when Fluphenazine is combined with Eperisone.Approved
FlurazepamThe risk or severity of adverse effects can be increased when Flurazepam is combined with Eperisone.Approved, Illicit, Investigational
FluspirileneThe risk or severity of adverse effects can be increased when Fluspirilene is combined with Eperisone.Approved, Investigational
Fluticasone propionateThe risk or severity of adverse effects can be increased when Fluticasone propionate is combined with Eperisone.Approved
FlutrimazoleThe therapeutic efficacy of Flutrimazole can be increased when used in combination with Eperisone.Experimental
FluvoxamineThe risk or severity of adverse effects can be increased when Eperisone is combined with Fluvoxamine.Approved, Investigational
FosamprenavirThe metabolism of Eperisone can be decreased when combined with Fosamprenavir.Approved
FosaprepitantThe serum concentration of Eperisone can be increased when it is combined with Fosaprepitant.Approved
FosphenytoinThe serum concentration of Fosphenytoin can be increased when it is combined with Eperisone.Approved, Investigational
FospropofolThe risk or severity of adverse effects can be increased when Fospropofol is combined with Eperisone.Approved, Illicit, Investigational
FramycetinThe risk or severity of adverse effects can be increased when Eperisone is combined with Framycetin.Approved
FrovatriptanThe risk or severity of adverse effects can be increased when Eperisone is combined with Frovatriptan.Approved, Investigational
FurazolidoneThe risk or severity of adverse effects can be increased when Furazolidone is combined with Eperisone.Approved, Investigational, Vet Approved
Fusidic AcidThe serum concentration of Eperisone can be increased when it is combined with Fusidic Acid.Approved, Investigational
GabapentinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Eperisone.Approved, Investigational
Gabapentin EnacarbilThe risk or severity of adverse effects can be increased when Gabapentin Enacarbil is combined with Eperisone.Approved, Investigational
GaboxadolThe risk or severity of adverse effects can be increased when Gaboxadol is combined with Eperisone.Investigational
GallamineEperisone may increase the neuromuscular blocking activities of Gallamine.Experimental
Gallamine TriethiodideEperisone may increase the neuromuscular blocking activities of Gallamine Triethiodide.Approved
Gamma Hydroxybutyric AcidThe risk or severity of adverse effects can be increased when Gamma Hydroxybutyric Acid is combined with Eperisone.Approved, Illicit, Investigational
Gantacurium ChlorideThe risk or severity of adverse effects can be increased when Eperisone is combined with Gantacurium Chloride.Investigational
GedocarnilThe risk or severity of adverse effects can be increased when Gedocarnil is combined with Eperisone.Experimental
GeneticinThe risk or severity of adverse effects can be increased when Eperisone is combined with Geneticin.Experimental
GentamicinThe risk or severity of adverse effects can be increased when Eperisone is combined with Gentamicin.Approved, Vet Approved
GENTAMICIN C1AThe risk or severity of adverse effects can be increased when Eperisone is combined with GENTAMICIN C1A.Experimental
GepironeThe risk or severity of adverse effects can be increased when Gepirone is combined with Eperisone.Investigational
GlutethimideThe risk or severity of adverse effects can be increased when Glutethimide is combined with Eperisone.Approved, Illicit
GlycerinThe therapeutic efficacy of Glycerin can be decreased when used in combination with Eperisone.Approved, Investigational
GranisetronThe risk or severity of adverse effects can be increased when Eperisone is combined with Granisetron.Approved, Investigational
GuanfacineThe risk or severity of adverse effects can be increased when Guanfacine is combined with Eperisone.Approved, Investigational
HalazepamThe risk or severity of adverse effects can be increased when Halazepam is combined with Eperisone.Approved, Illicit, Withdrawn
HaloperidolThe risk or severity of adverse effects can be increased when Haloperidol is combined with Eperisone.Approved
HalothaneThe risk or severity of adverse effects can be increased when Halothane is combined with Eperisone.Approved, Vet Approved
HarmalineThe risk or severity of adverse effects can be increased when Harmaline is combined with Eperisone.Experimental
HeptabarbitalThe risk or severity of adverse effects can be increased when Heptabarbital is combined with Eperisone.Approved
HeroinThe risk or severity of adverse effects can be increased when Heroin is combined with Eperisone.Approved, Illicit, Investigational
HexafluroniumThe risk or severity of adverse effects can be increased when Eperisone is combined with Hexafluronium.Approved
HexamethoniumThe risk or severity of adverse effects can be increased when Eperisone is combined with Hexamethonium.Experimental
HexapropymateThe risk or severity of adverse effects can be increased when Hexapropymate is combined with Eperisone.Experimental
HexobarbitalThe metabolism of Eperisone can be increased when combined with Hexobarbital.Approved
HydracarbazineThe risk or severity of adverse effects can be increased when Hydracarbazine is combined with Eperisone.Experimental
HydrocodoneEperisone may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.Approved, Illicit
HydromorphoneThe risk or severity of adverse effects can be increased when Hydromorphone is combined with Eperisone.Approved, Illicit
HydroxyzineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Eperisone.Approved
Hygromycin BThe risk or severity of adverse effects can be increased when Eperisone is combined with Hygromycin B.Vet Approved
HypericinThe risk or severity of adverse effects can be increased when Hypericin is combined with Eperisone.Investigational
IdalopirdineThe risk or severity of adverse effects can be increased when Eperisone is combined with Idalopirdine.Investigational
IdelalisibThe metabolism of Eperisone can be decreased when combined with Idelalisib.Approved
IfenprodilThe risk or severity of adverse effects can be increased when Ifenprodil is combined with Eperisone.Approved, Investigational, Withdrawn
IferanserinThe risk or severity of adverse effects can be increased when Eperisone is combined with Iferanserin.Investigational
IloperidoneThe risk or severity of hypotension can be increased when Iloperidone is combined with Eperisone.Approved
ImagabalinThe risk or severity of adverse effects can be increased when Imagabalin is combined with Eperisone.Investigational
ImatinibThe metabolism of Eperisone can be decreased when combined with Imatinib.Approved
ImipramineThe risk or severity of hypotension can be increased when Imipramine is combined with Eperisone.Approved
Imipramine oxideThe risk or severity of adverse effects can be increased when Imipramine oxide is combined with Eperisone.Experimental
IndalpineThe risk or severity of adverse effects can be increased when Eperisone is combined with Indalpine.Investigational, Withdrawn
IndinavirThe metabolism of Eperisone can be decreased when combined with Indinavir.Approved
IndiplonThe risk or severity of adverse effects can be increased when Indiplon is combined with Eperisone.Investigational
IndoraminThe risk or severity of hypotension can be increased when Indoramin is combined with Eperisone.Withdrawn
IprazochromeThe risk or severity of adverse effects can be increased when Eperisone is combined with Iprazochrome.Experimental
IprindoleThe risk or severity of adverse effects can be increased when Iprindole is combined with Eperisone.Experimental
IproclozideThe risk or severity of adverse effects can be increased when Iproclozide is combined with Eperisone.Withdrawn
IproniazidThe risk or severity of adverse effects can be increased when Iproniazid is combined with Eperisone.Withdrawn
IsavuconazoleThe serum concentration of Eperisone can be increased when it is combined with Isavuconazole.Approved, Investigational
IsavuconazoniumThe metabolism of Eperisone can be decreased when combined with Isavuconazonium.Approved, Investigational
IsepamicinThe risk or severity of adverse effects can be increased when Eperisone is combined with Isepamicin.Experimental
IsocarboxazidThe risk or severity of adverse effects can be increased when Isocarboxazid is combined with Eperisone.Approved
IsoconazoleThe therapeutic efficacy of Isoconazole can be increased when used in combination with Eperisone.Approved
IsofluraneThe risk or severity of adverse effects can be increased when Isoflurane is combined with Eperisone.Approved, Vet Approved
IsoniazidThe metabolism of Eperisone can be decreased when combined with Isoniazid.Approved, Investigational
ItraconazoleThe metabolism of Eperisone can be decreased when combined with Itraconazole.Approved, Investigational
IvacaftorThe serum concentration of Eperisone can be increased when it is combined with Ivacaftor.Approved
KanamycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Kanamycin.Approved, Investigational, Vet Approved
KetamineThe risk or severity of adverse effects can be increased when Ketamine is combined with Eperisone.Approved, Vet Approved
KetanserinThe risk or severity of adverse effects can be increased when Eperisone is combined with Ketanserin.Investigational
KetazolamThe risk or severity of adverse effects can be increased when Ketazolam is combined with Eperisone.Approved
KetobemidoneThe risk or severity of adverse effects can be increased when Ketobemidone is combined with Eperisone.Approved, Investigational
KetoconazoleThe metabolism of Eperisone can be decreased when combined with Ketoconazole.Approved, Investigational
L-TryptophanThe risk or severity of adverse effects can be increased when L-Tryptophan is combined with Eperisone.Approved, Nutraceutical, Withdrawn
LabetalolThe risk or severity of hypotension can be increased when Labetalol is combined with Eperisone.Approved
LacosamideThe risk or severity of adverse effects can be increased when Lacosamide is combined with Eperisone.Approved
LactitolThe therapeutic efficacy of Lactitol can be decreased when used in combination with Eperisone.Investigational
LactuloseThe therapeutic efficacy of Lactulose can be decreased when used in combination with Eperisone.Approved
LamotrigineThe risk or severity of adverse effects can be increased when Lamotrigine is combined with Eperisone.Approved, Investigational
LanicemineThe risk or severity of adverse effects can be increased when Lanicemine is combined with Eperisone.Investigational
LasmiditanThe risk or severity of adverse effects can be increased when Eperisone is combined with Lasmiditan.Investigational
LevetiracetamThe risk or severity of adverse effects can be increased when Levetiracetam is combined with Eperisone.Approved, Investigational
LevocabastineThe risk or severity of adverse effects can be increased when Eperisone is combined with Levocabastine.Approved, Investigational
LevocetirizineThe risk or severity of adverse effects can be increased when Levocetirizine is combined with Eperisone.Approved
LevodopaThe risk or severity of adverse effects can be increased when Levodopa is combined with Eperisone.Approved
Levomethadyl AcetateThe risk or severity of adverse effects can be increased when Levomethadyl Acetate is combined with Eperisone.Approved, Investigational
LevomilnacipranThe risk or severity of adverse effects can be increased when Eperisone is combined with Levomilnacipran.Approved, Investigational
LevorphanolThe risk or severity of adverse effects can be increased when Levorphanol is combined with Eperisone.Approved
LinaclotideThe therapeutic efficacy of Linaclotide can be decreased when used in combination with Eperisone.Approved
LincomycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Lincomycin.Approved, Vet Approved
LinezolidThe risk or severity of adverse effects can be increased when Eperisone is combined with Linezolid.Approved, Investigational
LisurideThe risk or severity of adverse effects can be increased when Eperisone is combined with Lisuride.Approved, Investigational
Lithium carbonateThe risk or severity of adverse effects can be increased when Eperisone is combined with Lithium carbonate.Approved
Lithium cationThe risk or severity of adverse effects can be increased when Lithium cation is combined with Eperisone.Experimental
LofentanilThe risk or severity of adverse effects can be increased when Lofentanil is combined with Eperisone.Illicit
LofepramineThe risk or severity of adverse effects can be increased when Lofepramine is combined with Eperisone.Experimental
LofexidineThe therapeutic efficacy of Eperisone can be increased when used in combination with Lofexidine.Approved, Investigational
LopinavirThe metabolism of Eperisone can be decreased when combined with Lopinavir.Approved
LoprazolamThe risk or severity of adverse effects can be increased when Loprazolam is combined with Eperisone.Experimental
LoratadineThe risk or severity of adverse effects can be increased when Loratadine is combined with Eperisone.Approved, Investigational
LorazepamThe risk or severity of adverse effects can be increased when Lorazepam is combined with Eperisone.Approved
LorcaserinThe risk or severity of adverse effects can be increased when Eperisone is combined with Lorcaserin.Approved
LormetazepamThe risk or severity of adverse effects can be increased when Lormetazepam is combined with Eperisone.Approved
LorpiprazoleThe serum concentration of Eperisone can be increased when it is combined with Lorpiprazole.Approved
LortalamineThe risk or severity of adverse effects can be increased when Eperisone is combined with Lortalamine.Experimental
LovastatinThe metabolism of Eperisone can be decreased when combined with Lovastatin.Approved, Investigational
LoxapineThe risk or severity of adverse effects can be increased when Loxapine is combined with Eperisone.Approved
LubiprostoneThe therapeutic efficacy of Lubiprostone can be decreased when used in combination with Eperisone.Approved, Investigational
LuliconazoleThe serum concentration of Eperisone can be increased when it is combined with Luliconazole.Approved
LumacaftorThe metabolism of Eperisone can be increased when combined with Lumacaftor.Approved
LumateperoneThe risk or severity of adverse effects can be increased when Eperisone is combined with Lumateperone.Investigational
LurasidoneThe risk or severity of adverse effects can be increased when Lurasidone is combined with Eperisone.Approved, Investigational
LymecyclineThe risk or severity of adverse effects can be increased when Eperisone is combined with Lymecycline.Approved, Investigational
Lysergic Acid DiethylamideThe risk or severity of adverse effects can be increased when Lysergic Acid Diethylamide is combined with Eperisone.Illicit, Investigational, Withdrawn
m-ChlorophenylpiperazineThe risk or severity of adverse effects can be increased when Eperisone is combined with m-Chlorophenylpiperazine.Investigational
Magnesium acetateThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium acetate.Approved
Magnesium acetate tetrahydrateThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium acetate tetrahydrate.Approved
Magnesium Aluminum SilicateThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium Aluminum Silicate.Approved
Magnesium aspartateThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium aspartate.Experimental
Magnesium carbonateThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium carbonate.Approved, Investigational
Magnesium cationThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium cation.Approved, Nutraceutical
Magnesium chlorideThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium chloride.Approved
Magnesium citrateThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium citrate.Approved
Magnesium gluconateThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium gluconate.Approved, Investigational
Magnesium glycinateThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium glycinate.Approved
Magnesium hydroxideThe risk or severity of hypotension and neuromuscular blockade can be increased when Eperisone is combined with Magnesium hydroxide.Approved, Investigational
Magnesium orotateThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium orotate.Experimental
Magnesium oxideThe risk or severity of hypotension and neuromuscular blockade can be increased when Eperisone is combined with Magnesium oxide.Approved
Magnesium peroxideThe therapeutic efficacy of Magnesium peroxide can be decreased when used in combination with Eperisone.Experimental
Magnesium phosphateThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium phosphate.Experimental
Magnesium salicylateThe risk or severity of hypotension and neuromuscular blockade can be increased when Eperisone is combined with Magnesium salicylate.Approved
Magnesium silicateThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium silicate.Approved
Magnesium stearateThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium stearate.Investigational
Magnesium sulfateThe therapeutic efficacy of Eperisone can be increased when used in combination with Magnesium sulfate.Approved, Investigational, Vet Approved
Magnesium TrisilicateThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium Trisilicate.Approved
MannitolThe therapeutic efficacy of Mannitol can be decreased when used in combination with Eperisone.Approved, Investigational
MaprotilineThe risk or severity of adverse effects can be increased when Maprotiline is combined with Eperisone.Approved, Investigational
MazindolThe risk or severity of adverse effects can be increased when Mazindol is combined with Eperisone.Approved, Investigational
MebanazineThe risk or severity of adverse effects can be increased when Mebanazine is combined with Eperisone.Withdrawn
MebicarThe risk or severity of adverse effects can be increased when Mebicar is combined with Eperisone.Experimental
MebutamateThe risk or severity of adverse effects can be increased when Mebutamate is combined with Eperisone.Approved
MecamylamineThe risk or severity of adverse effects can be increased when Eperisone is combined with Mecamylamine.Approved, Investigational
MeclizineThe risk or severity of adverse effects can be increased when Meclizine is combined with Eperisone.Approved
MedazepamThe risk or severity of adverse effects can be increased when Medazepam is combined with Eperisone.Experimental
MedetomidineThe risk or severity of adverse effects can be increased when Medetomidine is combined with Eperisone.Vet Approved
MedifoxamineThe risk or severity of adverse effects can be increased when Medifoxamine is combined with Eperisone.Experimental
MelatoninThe risk or severity of adverse effects can be increased when Melatonin is combined with Eperisone.Approved, Nutraceutical, Vet Approved
MelitracenThe risk or severity of adverse effects can be increased when Melitracen is combined with Eperisone.Experimental, Investigational
MelperoneThe risk or severity of adverse effects can be increased when Melperone is combined with Eperisone.Approved, Investigational
MephenesinThe risk or severity of adverse effects can be increased when Eperisone is combined with Mephenesin.Approved
MephenoxaloneThe risk or severity of adverse effects can be increased when Mephenoxalone is combined with Eperisone.Experimental
MephenytoinThe risk or severity of adverse effects can be increased when Mephenytoin is combined with Eperisone.Investigational, Withdrawn
MeprobamateThe risk or severity of adverse effects can be increased when Meprobamate is combined with Eperisone.Approved, Illicit
MeptazinolThe risk or severity of adverse effects can be increased when Meptazinol is combined with Eperisone.Experimental
MesoridazineThe risk or severity of adverse effects can be increased when Mesoridazine is combined with Eperisone.Approved, Investigational
MetaxaloneThe risk or severity of adverse effects can be increased when Metaxalone is combined with Eperisone.Approved
MetergolineThe risk or severity of adverse effects can be increased when Eperisone is combined with Metergoline.Experimental
MethacyclineThe risk or severity of adverse effects can be increased when Eperisone is combined with Methacycline.Approved, Investigational
MethadoneThe risk or severity of adverse effects can be increased when Methadone is combined with Eperisone.Approved
Methadyl AcetateThe risk or severity of adverse effects can be increased when Methadyl Acetate is combined with Eperisone.Approved, Illicit
MethamphetamineThe risk or severity of adverse effects can be increased when Methamphetamine is combined with Eperisone.Approved, Illicit
MethapyrileneThe risk or severity of adverse effects can be increased when Methapyrilene is combined with Eperisone.Withdrawn
MethaqualoneThe risk or severity of adverse effects can be increased when Methaqualone is combined with Eperisone.Illicit, Withdrawn
MetharbitalThe risk or severity of adverse effects can be increased when Eperisone is combined with Metharbital.Withdrawn
MethohexitalThe metabolism of Eperisone can be increased when combined with Methohexital.Approved
MethotrimeprazineEperisone may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.Approved, Investigational
MethoxyfluraneThe risk or severity of adverse effects can be increased when Methoxyflurane is combined with Eperisone.Approved, Investigational, Vet Approved
MethsuximideThe risk or severity of adverse effects can be increased when Methsuximide is combined with Eperisone.Approved
Methyl celluloseThe therapeutic efficacy of Methyl cellulose can be decreased when used in combination with Eperisone.Approved
Methylene blueThe risk or severity of adverse effects can be increased when Methylene blue is combined with Eperisone.Approved, Investigational
MethylpentynolThe risk or severity of adverse effects can be increased when Methylpentynol is combined with Eperisone.Experimental
MethylphenidateThe risk or severity of adverse effects can be increased when Eperisone is combined with Methylphenidate.Approved, Investigational
MethylphenobarbitalThe metabolism of Eperisone can be increased when combined with Methylphenobarbital.Approved
MethyprylonThe risk or severity of adverse effects can be increased when Methyprylon is combined with Eperisone.Approved, Illicit, Withdrawn
MethysergideThe risk or severity of adverse effects can be increased when Eperisone is combined with Methysergide.Approved
MetocurineEperisone may increase the neuromuscular blocking activities of Metocurine.Approved
Metocurine IodideEperisone may increase the neuromuscular blocking activities of Metocurine Iodide.Approved, Withdrawn
MetyrosineEperisone may increase the sedative activities of Metyrosine.Approved
MianserinThe risk or severity of adverse effects can be increased when Mianserin is combined with Eperisone.Approved, Investigational
MibefradilThe metabolism of Eperisone can be decreased when combined with Mibefradil.Investigational, Withdrawn
MiconazoleThe metabolism of Eperisone can be decreased when combined with Miconazole.Approved, Investigational, Vet Approved
MicronomicinThe risk or severity of adverse effects can be increased when Eperisone is combined with Micronomicin.Experimental
MidazolamThe risk or severity of adverse effects can be increased when Midazolam is combined with Eperisone.Approved, Illicit
MidomafetamineThe risk or severity of adverse effects can be increased when Midomafetamine is combined with Eperisone.Experimental, Illicit, Investigational
MifepristoneThe serum concentration of Eperisone can be increased when it is combined with Mifepristone.Approved, Investigational
MilnacipranThe risk or severity of adverse effects can be increased when Eperisone is combined with Milnacipran.Approved, Investigational
MinaprineThe risk or severity of adverse effects can be increased when Minaprine is combined with Eperisone.Approved
Mineral oilThe therapeutic efficacy of Mineral oil can be decreased when used in combination with Eperisone.Approved, Vet Approved
MinocyclineMinocycline may increase the central nervous system depressant (CNS depressant) activities of Eperisone.Approved, Investigational
MirtazapineEperisone may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.Approved
MitotaneThe serum concentration of Eperisone can be decreased when it is combined with Mitotane.Approved
MivacuriumEperisone may increase the neuromuscular blocking activities of Mivacurium.Approved
MK-212The risk or severity of adverse effects can be increased when Eperisone is combined with MK-212.Investigational
MMDAThe risk or severity of adverse effects can be increased when Eperisone is combined with MMDA.Experimental, Illicit
MoclobemideThe risk or severity of adverse effects can be increased when Moclobemide is combined with Eperisone.Approved, Investigational
ModafinilThe serum concentration of Eperisone can be decreased when it is combined with Modafinil.Approved, Investigational
MolindoneThe risk or severity of adverse effects can be increased when Molindone is combined with Eperisone.Approved
MoperoneThe risk or severity of adverse effects can be increased when Eperisone is combined with Moperone.Experimental
MoricizineThe risk or severity of adverse effects can be increased when Eperisone is combined with Moricizine.Approved, Investigational, Withdrawn
MorphineThe risk or severity of adverse effects can be increased when Morphine is combined with Eperisone.Approved, Investigational
MosapramineThe risk or severity of adverse effects can be increased when Eperisone is combined with Mosapramine.Experimental
MosaprideThe risk or severity of adverse effects can be increased when Eperisone is combined with Mosapride.Investigational
MRK-409The risk or severity of adverse effects can be increased when MRK-409 is combined with Eperisone.Experimental
N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamineThe risk or severity of adverse effects can be increased when Eperisone is combined with N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine.Experimental
NabiloneNabilone may increase the central nervous system depressant (CNS depressant) activities of Eperisone.Approved, Investigational
NafcillinThe therapeutic efficacy of Eperisone can be decreased when used in combination with Nafcillin.Approved, Investigational
NaftidrofurylThe risk or severity of adverse effects can be increased when Eperisone is combined with Naftidrofuryl.Experimental
NalbuphineThe risk or severity of adverse effects can be increased when Nalbuphine is combined with Eperisone.Approved
NaloxoneThe metabolism of Eperisone can be decreased when combined with Naloxone.Approved, Vet Approved
NaluzotanThe risk or severity of adverse effects can be increased when Eperisone is combined with Naluzotan.Investigational
NaratriptanThe risk or severity of adverse effects can be increased when Eperisone is combined with Naratriptan.Approved, Investigational
NaronaprideThe risk or severity of adverse effects can be increased when Eperisone is combined with Naronapride.Investigational
NeamineThe risk or severity of adverse effects can be increased when Eperisone is combined with Neamine.Experimental
NefazodoneThe risk or severity of adverse effects can be increased when Eperisone is combined with Nefazodone.Approved, Withdrawn
NefiracetamThe risk or severity of adverse effects can be increased when Nefiracetam is combined with Eperisone.Investigational
NelfinavirThe metabolism of Eperisone can be decreased when combined with Nelfinavir.Approved
NeocitrullamonThe risk or severity of adverse effects can be increased when Eperisone is combined with Neocitrullamon.Experimental
NeomycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Neomycin.Approved, Vet Approved
NeosaxitoxinThe risk or severity of adverse effects can be increased when Eperisone is combined with Neosaxitoxin.Investigational
NetilmicinThe risk or severity of adverse effects can be increased when Eperisone is combined with Netilmicin.Approved, Investigational
NetupitantThe serum concentration of Eperisone can be increased when it is combined with Netupitant.Approved, Investigational
NevirapineThe metabolism of Eperisone can be increased when combined with Nevirapine.Approved
NialamideThe risk or severity of adverse effects can be increased when Nialamide is combined with Eperisone.Withdrawn
NiaprazineThe risk or severity of adverse effects can be increased when Niaprazine is combined with Eperisone.Experimental
NicardipineThe risk or severity of hypotension can be increased when Nicardipine is combined with Eperisone.Approved, Investigational
NicergolineThe risk or severity of hypotension can be increased when Nicergoline is combined with Eperisone.Approved, Investigational
NiguldipineThe risk or severity of hypotension can be increased when Niguldipine is combined with Eperisone.Experimental
NilotinibThe metabolism of Eperisone can be decreased when combined with Nilotinib.Approved, Investigational
NisoxetineThe risk or severity of adverse effects can be increased when Eperisone is combined with Nisoxetine.Experimental
NitrazepamThe risk or severity of adverse effects can be increased when Nitrazepam is combined with Eperisone.Approved
NitroprussideEperisone may increase the hypotensive activities of Nitroprusside.Approved, Investigational
Nitrous oxideThe risk or severity of adverse effects can be increased when Nitrous oxide is combined with Eperisone.Approved, Vet Approved
NomifensineThe risk or severity of adverse effects can be increased when Nomifensine is combined with Eperisone.Withdrawn
NordazepamThe risk or severity of adverse effects can be increased when Nordazepam is combined with Eperisone.Approved
NormethadoneThe risk or severity of adverse effects can be increased when Normethadone is combined with Eperisone.Approved, Illicit
NortriptylineThe risk or severity of hypotension can be increased when Nortriptyline is combined with Eperisone.Approved
OctamoxinThe risk or severity of adverse effects can be increased when Octamoxin is combined with Eperisone.Withdrawn
OlanzapineThe risk or severity of hypotension can be increased when Olanzapine is combined with Eperisone.Approved, Investigational
OlaparibThe metabolism of Eperisone can be decreased when combined with Olaparib.Approved
OlopatadineThe risk or severity of adverse effects can be increased when Olopatadine is combined with Eperisone.Approved
OmoconazoleThe therapeutic efficacy of Omoconazole can be increased when used in combination with Eperisone.Experimental
OndansetronThe risk or severity of adverse effects can be increased when Ondansetron is combined with Eperisone.Approved
OpipramolThe risk or severity of adverse effects can be increased when Opipramol is combined with Eperisone.Investigational
OpiumThe risk or severity of adverse effects can be increased when Opium is combined with Eperisone.Approved, Illicit
OrphenadrineEperisone may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.Approved
OrvepitantThe risk or severity of adverse effects can be increased when Orvepitant is combined with Eperisone.Investigational
OsanetantThe risk or severity of adverse effects can be increased when Osanetant is combined with Eperisone.Investigational
OsimertinibThe serum concentration of Eperisone can be increased when it is combined with Osimertinib.Approved
OxaflozaneThe risk or severity of adverse effects can be increased when Oxaflozane is combined with Eperisone.Experimental
OxaprotilineThe risk or severity of adverse effects can be increased when Oxaprotiline is combined with Eperisone.Experimental
OxazepamThe risk or severity of adverse effects can be increased when Oxazepam is combined with Eperisone.Approved
OxcarbazepineThe risk or severity of adverse effects can be increased when Oxcarbazepine is combined with Eperisone.Approved
OxiconazoleThe therapeutic efficacy of Oxiconazole can be increased when used in combination with Eperisone.Approved
OxiracetamThe risk or severity of adverse effects can be increased when Oxiracetam is combined with Eperisone.Experimental
OxitriptanThe risk or severity of adverse effects can be increased when Oxitriptan is combined with Eperisone.Approved, Investigational, Nutraceutical
OxprenololThe risk or severity of adverse effects can be increased when Oxprenolol is combined with Eperisone.Approved
OxycodoneThe risk or severity of adverse effects can be increased when Oxycodone is combined with Eperisone.Approved, Illicit, Investigational
OxymorphoneThe risk or severity of adverse effects can be increased when Oxymorphone is combined with Eperisone.Approved, Investigational, Vet Approved
OxypertineThe risk or severity of adverse effects can be increased when Eperisone is combined with Oxypertine.Experimental
OxyphenisatinThe therapeutic efficacy of Oxyphenisatin can be decreased when used in combination with Eperisone.Investigational, Withdrawn
OxytetracyclineThe risk or severity of adverse effects can be increased when Eperisone is combined with Oxytetracycline.Approved, Investigational, Vet Approved
PalbociclibThe serum concentration of Eperisone can be increased when it is combined with Palbociclib.Approved, Investigational
PaliperidoneThe risk or severity of hypotension can be increased when Paliperidone is combined with Eperisone.Approved
PalonosetronThe risk or severity of adverse effects can be increased when Eperisone is combined with Palonosetron.Approved, Investigational
PancuroniumEperisone may increase the neuromuscular blocking activities of Pancuronium.Approved
ParaldehydeEperisone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.Approved, Investigational
ParamethadioneThe risk or severity of adverse effects can be increased when Eperisone is combined with Paramethadione.Approved
PargylineThe risk or severity of adverse effects can be increased when Pargyline is combined with Eperisone.Approved
ParomomycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Paromomycin.Approved, Investigational
ParoxetineThe risk or severity of adverse effects can be increased when Eperisone is combined with Paroxetine.Approved, Investigational
Patent BlueThe therapeutic efficacy of Eperisone can be decreased when used in combination with Patent Blue.Approved
PenbutololThe risk or severity of adverse effects can be increased when Eperisone is combined with Penbutolol.Approved, Investigational
PenfluridolThe risk or severity of adverse effects can be increased when Penfluridol is combined with Eperisone.Experimental
PenimepicyclineThe risk or severity of adverse effects can be increased when Eperisone is combined with Penimepicycline.Experimental
PentaerithritylThe therapeutic efficacy of Pentaerithrityl can be decreased when used in combination with Eperisone.Experimental
PentazocineThe risk or severity of adverse effects can be increased when Pentazocine is combined with Eperisone.Approved, Vet Approved
PentobarbitalThe metabolism of Eperisone can be increased when combined with Pentobarbital.Approved, Investigational, Vet Approved
PerampanelPerampanel may increase the central nervous system depressant (CNS depressant) activities of Eperisone.Approved
PerazineThe risk or severity of adverse effects can be increased when Perazine is combined with Eperisone.Approved, Investigational
PergolideThe risk or severity of adverse effects can be increased when Eperisone is combined with Pergolide.Approved, Investigational, Vet Approved, Withdrawn
PerospironeThe risk or severity of adverse effects can be increased when Perospirone is combined with Eperisone.Approved
PerphenazineThe risk or severity of adverse effects can be increased when Perphenazine is combined with Eperisone.Approved
PethidineThe risk or severity of adverse effects can be increased when Pethidine is combined with Eperisone.Approved
PhenacemideThe risk or severity of adverse effects can be increased when Eperisone is combined with Phenacemide.Approved
PhenazocineThe risk or severity of adverse effects can be increased when Phenazocine is combined with Eperisone.Experimental
PhencyclidineThe risk or severity of adverse effects can be increased when Phencyclidine is combined with Eperisone.Illicit
PhenelzineThe risk or severity of adverse effects can be increased when Phenelzine is combined with Eperisone.Approved
PhenethylamineThe risk or severity of adverse effects can be increased when Phenethylamine is combined with Eperisone.Experimental
PheneturideThe risk or severity of adverse effects can be increased when Pheneturide is combined with Eperisone.Experimental
PhenibutThe risk or severity of adverse effects can be increased when Phenibut is combined with Eperisone.Experimental
PheniprazineThe risk or severity of adverse effects can be increased when Pheniprazine is combined with Eperisone.Withdrawn
PhenobarbitalThe metabolism of Eperisone can be increased when combined with Phenobarbital.Approved, Investigational
PhenolphthaleinThe therapeutic efficacy of Phenolphthalein can be decreased when used in combination with Eperisone.Approved, Withdrawn
PhenoperidineThe risk or severity of adverse effects can be increased when Phenoperidine is combined with Eperisone.Experimental
PhenoxybenzamineThe risk or severity of hypotension can be increased when Phenoxybenzamine is combined with Eperisone.Approved
PhenoxypropazineThe risk or severity of adverse effects can be increased when Phenoxypropazine is combined with Eperisone.Withdrawn
PhenprobamateThe risk or severity of adverse effects can be increased when Eperisone is combined with Phenprobamate.Experimental
PhensuximideThe risk or severity of adverse effects can be increased when Eperisone is combined with Phensuximide.Approved
PhentermineThe risk or severity of adverse effects can be increased when Eperisone is combined with Phentermine.Approved, Illicit
PhentolamineThe risk or severity of hypotension can be increased when Phentolamine is combined with Eperisone.Approved
PhenytoinThe serum concentration of Phenytoin can be increased when it is combined with Eperisone.Approved, Vet Approved
PiclozotanThe risk or severity of adverse effects can be increased when Eperisone is combined with Piclozotan.Investigational
Picosulfuric acidThe therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Eperisone.Approved
PimavanserinThe risk or severity of adverse effects can be increased when Eperisone is combined with Pimavanserin.Approved, Investigational
PimozideThe risk or severity of adverse effects can be increased when Pimozide is combined with Eperisone.Approved
PinazepamThe risk or severity of adverse effects can be increased when Pinazepam is combined with Eperisone.Experimental
PindololThe risk or severity of adverse effects can be increased when Eperisone is combined with Pindolol.Approved, Investigational
PipamperoneThe risk or severity of adverse effects can be increased when Pipamperone is combined with Eperisone.Approved, Investigational
PipecuroniumEperisone may increase the neuromuscular blocking activities of Pipecuronium.Approved
PipotiazineThe risk or severity of adverse effects can be increased when Pipotiazine is combined with Eperisone.Approved, Investigational
PiritramideThe risk or severity of adverse effects can be increased when Piritramide is combined with Eperisone.Approved, Investigational
PirlimycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Pirlimycin.Vet Approved
PirlindoleThe risk or severity of adverse effects can be increased when Pirlindole is combined with Eperisone.Approved
PitolisantThe serum concentration of Eperisone can be decreased when it is combined with Pitolisant.Approved, Investigational
PivagabineThe risk or severity of adverse effects can be increased when Pivagabine is combined with Eperisone.Investigational
PivhydrazineThe risk or severity of adverse effects can be increased when Pivhydrazine is combined with Eperisone.Withdrawn
PizotifenThe risk or severity of hypotension can be increased when Pizotifen is combined with Eperisone.Approved
Plantago seedThe therapeutic efficacy of Plantago seed can be decreased when used in combination with Eperisone.Approved, Investigational
PlazomicinThe risk or severity of adverse effects can be increased when Eperisone is combined with Plazomicin.Approved, Investigational
PlecanatideThe therapeutic efficacy of Plecanatide can be decreased when used in combination with Eperisone.Approved, Investigational
PolycarbophilThe therapeutic efficacy of Polycarbophil can be decreased when used in combination with Eperisone.Approved
Polyethylene glycolThe therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Eperisone.Approved, Vet Approved
Polymyxin B SulfateThe risk or severity of adverse effects can be increased when Eperisone is combined with Polymyxin B Sulfate.Approved, Vet Approved
PomalidomideThe risk or severity of adverse effects can be increased when Pomalidomide is combined with Eperisone.Approved
PosaconazoleThe metabolism of Eperisone can be decreased when combined with Posaconazole.Approved, Investigational, Vet Approved
Potassium acetateThe therapeutic efficacy of Potassium acetate can be decreased when used in combination with Eperisone.Approved, Investigational
PramipexoleEperisone may increase the sedative activities of Pramipexole.Approved, Investigational
PrazepamThe risk or severity of adverse effects can be increased when Prazepam is combined with Eperisone.Approved, Illicit
PrazosinThe risk or severity of hypotension can be increased when Prazosin is combined with Eperisone.Approved
PregabalinThe therapeutic efficacy of Eperisone can be increased when used in combination with Pregabalin.Approved, Illicit, Investigational
PridinolThe risk or severity of adverse effects can be increased when Eperisone is combined with Pridinol.Experimental
PrimidoneThe metabolism of Eperisone can be increased when combined with Primidone.Approved, Vet Approved
ProcainamideThe risk or severity of adverse effects can be increased when Eperisone is combined with Procainamide.Approved
ProcaineThe risk or severity of adverse effects can be increased when Procaine is combined with Eperisone.Approved, Investigational, Vet Approved
ProcarbazineThe risk or severity of adverse effects can be increased when Procarbazine is combined with Eperisone.Approved, Investigational
ProchlorperazineThe risk or severity of adverse effects can be increased when Prochlorperazine is combined with Eperisone.Approved, Vet Approved
ProgabideThe risk or severity of adverse effects can be increased when Progabide is combined with Eperisone.Approved, Investigational
PromazineThe risk or severity of hypotension can be increased when Promazine is combined with Eperisone.Approved, Vet Approved
PromethazineThe risk or severity of adverse effects can be increased when Promethazine is combined with Eperisone.Approved, Investigational
PropanididThe risk or severity of adverse effects can be increased when Propanidid is combined with Eperisone.Experimental
PropericiazineThe risk or severity of hypotension can be increased when Propericiazine is combined with Eperisone.Approved, Investigational
PropiomazineThe risk or severity of hypotension can be increased when Propiomazine is combined with Eperisone.Approved
PropiopromazineThe risk or severity of adverse effects can be increased when Eperisone is combined with Propiopromazine.Vet Approved
PropiverineThe risk or severity of hypotension can be increased when Propiverine is combined with Eperisone.Approved, Investigational
PropofolThe risk or severity of adverse effects can be increased when Propofol is combined with Eperisone.Approved, Investigational, Vet Approved
ProthipendylThe risk or severity of adverse effects can be increased when Eperisone is combined with Prothipendyl.Investigational
ProtriptylineThe risk or severity of adverse effects can be increased when Protriptyline is combined with Eperisone.Approved
ProxibarbalThe risk or severity of adverse effects can be increased when Proxibarbal is combined with Eperisone.Experimental
PrucaloprideThe therapeutic efficacy of Prucalopride can be decreased when used in combination with Eperisone.Approved
PRX-08066The risk or severity of adverse effects can be increased when Eperisone is combined with PRX-08066.Investigational
PseudoephedrineThe risk or severity of adverse effects can be increased when Eperisone is combined with Pseudoephedrine.Approved
PsilocybineThe risk or severity of adverse effects can be increased when Psilocybine is combined with Eperisone.Investigational
PuromycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Puromycin.Experimental
PyrantelThe risk or severity of adverse effects can be increased when Eperisone is combined with Pyrantel.Approved, Vet Approved
PyrithyldioneThe risk or severity of adverse effects can be increased when Pyrithyldione is combined with Eperisone.Experimental
QuazepamThe risk or severity of adverse effects can be increased when Quazepam is combined with Eperisone.Approved, Illicit
QuetiapineThe risk or severity of hypotension can be increased when Quetiapine is combined with Eperisone.Approved
QuinidineThe risk or severity of hypotension can be increased when Quinidine is combined with Eperisone.Approved, Investigational
QuinineThe metabolism of Eperisone can be increased when combined with Quinine.Approved
QuinupramineThe risk or severity of adverse effects can be increased when Quinupramine is combined with Eperisone.Experimental
RacloprideThe risk or severity of adverse effects can be increased when Raclopride is combined with Eperisone.Investigational
RamelteonThe risk or severity of adverse effects can be increased when Eperisone is combined with Ramelteon.Approved, Investigational
RamosetronThe risk or severity of adverse effects can be increased when Eperisone is combined with Ramosetron.Approved, Investigational
RapacuroniumEperisone may increase the neuromuscular blocking activities of Rapacuronium.Withdrawn
RasagilineThe risk or severity of adverse effects can be increased when Rasagiline is combined with Eperisone.Approved
RavuconazoleThe therapeutic efficacy of Ravuconazole can be increased when used in combination with Eperisone.Investigational
ReboxetineThe risk or severity of adverse effects can be increased when Reboxetine is combined with Eperisone.Approved, Investigational
RemacemideThe risk or severity of adverse effects can be increased when Remacemide is combined with Eperisone.Investigational
RemifentanilThe risk or severity of adverse effects can be increased when Remifentanil is combined with Eperisone.Approved
RemoxiprideThe risk or severity of adverse effects can be increased when Remoxipride is combined with Eperisone.Approved, Withdrawn
RenzaprideThe risk or severity of adverse effects can be increased when Eperisone is combined with Renzapride.Investigational
RepinotanThe risk or severity of adverse effects can be increased when Eperisone is combined with Repinotan.Investigational
ReposalThe risk or severity of adverse effects can be increased when Reposal is combined with Eperisone.Approved
ReserpineThe risk or severity of adverse effects can be increased when Reserpine is combined with Eperisone.Approved, Investigational
RibostamycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Ribostamycin.Approved, Investigational
RifampicinThe metabolism of Eperisone can be increased when combined with Rifampicin.Approved
RifamycinThe metabolism of Eperisone can be increased when combined with Rifamycin.Investigational
RifapentineThe metabolism of Eperisone can be increased when combined with Rifapentine.Approved, Investigational
RifaximinThe metabolism of Eperisone can be increased when combined with Rifaximin.Approved, Investigational
RiluzoleThe risk or severity of adverse effects can be increased when Riluzole is combined with Eperisone.Approved, Investigational
RimexoloneThe metabolism of Eperisone can be increased when combined with Rimexolone.Approved
RisperidoneThe risk or severity of hypotension can be increased when Risperidone is combined with Eperisone.Approved, Investigational
RitanserinThe risk or severity of adverse effects can be increased when Eperisone is combined with Ritanserin.Investigational
RitonavirThe metabolism of Eperisone can be decreased when combined with Ritonavir.Approved, Investigational
RizatriptanThe risk or severity of adverse effects can be increased when Eperisone is combined with Rizatriptan.Approved
RocuroniumEperisone may increase the neuromuscular blocking activities of Rocuronium.Approved
RolipramThe risk or severity of adverse effects can be increased when Rolipram is combined with Eperisone.Investigational
RolitetracyclineThe risk or severity of adverse effects can be increased when Eperisone is combined with Rolitetracycline.Approved
RomifidineThe risk or severity of adverse effects can be increased when Romifidine is combined with Eperisone.Vet Approved
RopiniroleEperisone may increase the sedative activities of Ropinirole.Approved, Investigational
RotigotineEperisone may increase the sedative activities of Rotigotine.Approved
RP-5063The risk or severity of adverse effects can be increased when Eperisone is combined with RP-5063.Investigational
RufinamideThe risk or severity of adverse effects can be increased when Rufinamide is combined with Eperisone.Approved
SafinamideThe risk or severity of adverse effects can be increased when Eperisone is combined with Safinamide.Approved, Investigational
SafrazineThe risk or severity of adverse effects can be increased when Safrazine is combined with Eperisone.Withdrawn
SaquinavirThe metabolism of Eperisone can be decreased when combined with Saquinavir.Approved, Investigational
SaredutantThe risk or severity of adverse effects can be increased when Saredutant is combined with Eperisone.Investigational
SarilumabThe therapeutic efficacy of Eperisone can be decreased when used in combination with Sarilumab.Approved, Investigational
SarpogrelateThe risk or severity of adverse effects can be increased when Eperisone is combined with Sarpogrelate.Investigational
ScopolamineThe risk or severity of adverse effects can be increased when Scopolamine is combined with Eperisone.Approved, Investigational
SecobarbitalThe metabolism of Eperisone can be increased when combined with Secobarbital.Approved, Vet Approved
SelegilineThe risk or severity of adverse effects can be increased when Selegiline is combined with Eperisone.Approved, Investigational, Vet Approved
SennosidesThe therapeutic efficacy of Sennosides can be decreased when used in combination with Eperisone.Approved
SerotoninThe risk or severity of adverse effects can be increased when Eperisone is combined with Serotonin.Investigational, Nutraceutical
SertaconazoleThe therapeutic efficacy of Sertaconazole can be increased when used in combination with Eperisone.Approved, Investigational
SertindoleThe risk or severity of adverse effects can be increased when Sertindole is combined with Eperisone.Approved, Investigational, Withdrawn
SertralineThe risk or severity of adverse effects can be increased when Eperisone is combined with Sertraline.Approved
SevofluraneThe risk or severity of adverse effects can be increased when Sevoflurane is combined with Eperisone.Approved, Vet Approved
SibutramineThe risk or severity of adverse effects can be increased when Sibutramine is combined with Eperisone.Approved, Illicit, Investigational, Withdrawn
SilodosinThe risk or severity of hypotension can be increased when Silodosin is combined with Eperisone.Approved
SiltuximabThe serum concentration of Eperisone can be decreased when it is combined with Siltuximab.Approved, Investigational
SimeprevirThe serum concentration of Eperisone can be increased when it is combined with Simeprevir.Approved
SisomicinThe risk or severity of adverse effects can be increased when Eperisone is combined with Sisomicin.Investigational
Sodium oxybateSodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Eperisone.Approved
Sodium phosphate, monobasicThe therapeutic efficacy of Sodium phosphate, monobasic can be decreased when used in combination with Eperisone.Approved
Sodium sulfateThe therapeutic efficacy of Sodium sulfate can be decreased when used in combination with Eperisone.Approved, Vet Approved
Sodium tartrateThe therapeutic efficacy of Sodium tartrate can be decreased when used in combination with Eperisone.Approved
SorbitolThe therapeutic efficacy of Sorbitol can be decreased when used in combination with Eperisone.Approved
St. John's WortThe serum concentration of Eperisone can be decreased when it is combined with St. John's Wort.Approved, Investigational, Nutraceutical
StiripentolThe serum concentration of Eperisone can be increased when it is combined with Stiripentol.Approved
StreptomycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Streptomycin.Approved, Vet Approved
StyramateThe risk or severity of adverse effects can be increased when Eperisone is combined with Styramate.Experimental
SuccinylcholineThe risk or severity of adverse effects can be increased when Eperisone is combined with Succinylcholine.Approved
SufentanilThe risk or severity of adverse effects can be increased when Sufentanil is combined with Eperisone.Approved, Investigational
SulconazoleThe therapeutic efficacy of Sulconazole can be increased when used in combination with Eperisone.Approved
SulpirideThe risk or severity of adverse effects can be increased when Sulpiride is combined with Eperisone.Approved, Investigational
SulthiameThe risk or severity of adverse effects can be increased when Sulthiame is combined with Eperisone.Experimental
SultoprideThe risk or severity of adverse effects can be increased when Sultopride is combined with Eperisone.Experimental
SumatriptanThe risk or severity of adverse effects can be increased when Eperisone is combined with Sumatriptan.Approved, Investigational
SuvorexantEperisone may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.Approved, Investigational
TalbutalThe risk or severity of adverse effects can be increased when Talbutal is combined with Eperisone.Approved, Illicit
TalopramThe risk or severity of adverse effects can be increased when Eperisone is combined with Talopram.Experimental
TamsulosinThe risk or severity of hypotension can be increased when Tamsulosin is combined with Eperisone.Approved, Investigational
TandospironeThe risk or severity of adverse effects can be increased when Tandospirone is combined with Eperisone.Investigational
TapentadolTapentadol may increase the central nervous system depressant (CNS depressant) activities of Eperisone.Approved
TasimelteonThe risk or severity of adverse effects can be increased when Eperisone is combined with Tasimelteon.Approved, Investigational
TD-8954The risk or severity of adverse effects can be increased when Eperisone is combined with TD-8954.Investigational
Tedizolid phosphateThe risk or severity of adverse effects can be increased when Eperisone is combined with Tedizolid phosphate.Approved
TegaserodThe risk or severity of adverse effects can be increased when Eperisone is combined with Tegaserod.Approved, Investigational, Withdrawn
TelaprevirThe metabolism of Eperisone can be decreased when combined with Telaprevir.Approved, Withdrawn
TelithromycinThe metabolism of Eperisone can be decreased when combined with Telithromycin.Approved
TemazepamThe risk or severity of adverse effects can be increased when Temazepam is combined with Eperisone.Approved, Investigational
TerazosinThe risk or severity of hypotension can be increased when Terazosin is combined with Eperisone.Approved
TerconazoleThe therapeutic efficacy of Terconazole can be increased when used in combination with Eperisone.Approved
TetracyclineThe risk or severity of adverse effects can be increased when Eperisone is combined with Tetracycline.Approved, Vet Approved
TetrahydrocannabivarinThe risk or severity of adverse effects can be increased when Eperisone is combined with Tetrahydrocannabivarin.Investigational
TetrahydropalmatineThe risk or severity of adverse effects can be increased when Tetrahydropalmatine is combined with Eperisone.Investigational
TetrazepamThe risk or severity of adverse effects can be increased when Eperisone is combined with Tetrazepam.Experimental
TetrodotoxinThe risk or severity of adverse effects can be increased when Tetrodotoxin is combined with Eperisone.Investigational
ThalidomideEperisone may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.Approved, Investigational, Withdrawn
ThiamylalThe metabolism of Eperisone can be increased when combined with Thiamylal.Approved, Vet Approved
ThiazinamThe risk or severity of adverse effects can be increased when Eperisone is combined with Thiazinam.Experimental
ThiethylperazineThe risk or severity of adverse effects can be increased when Eperisone is combined with Thiethylperazine.Withdrawn
ThiocolchicosideThe risk or severity of adverse effects can be increased when Eperisone is combined with Thiocolchicoside.Approved, Investigational
ThiopentalThe metabolism of Eperisone can be increased when combined with Thiopental.Approved, Vet Approved
ThiopropazateThe risk or severity of adverse effects can be increased when Eperisone is combined with Thiopropazate.Experimental
ThioproperazineThe risk or severity of hypotension can be increased when Thioproperazine is combined with Eperisone.Approved
ThioridazineThe risk or severity of hypotension can be increased when Thioridazine is combined with Eperisone.Approved, Withdrawn
ThiothixeneThe risk or severity of adverse effects can be increased when Thiothixene is combined with Eperisone.Approved
TiagabineThe risk or severity of adverse effects can be increased when Tiagabine is combined with Eperisone.Approved, Investigational
TianeptineThe risk or severity of adverse effects can be increased when Tianeptine is combined with Eperisone.Approved, Investigational
TiaprideThe risk or severity of adverse effects can be increased when Tiapride is combined with Eperisone.Approved, Investigational
TigecyclineThe risk or severity of adverse effects can be increased when Eperisone is combined with Tigecycline.Approved
TiletamineThe risk or severity of adverse effects can be increased when Tiletamine is combined with Eperisone.Vet Approved
TilidineThe risk or severity of adverse effects can be increased when Tilidine is combined with Eperisone.Experimental
TioconazoleThe therapeutic efficacy of Tioconazole can be increased when used in combination with Eperisone.Approved
TipranavirThe metabolism of Eperisone can be decreased when combined with Tipranavir.Approved, Investigational
TizanidineThe risk or severity of adverse effects can be increased when Tizanidine is combined with Eperisone.Approved, Investigational
TobramycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Tobramycin.Approved, Investigational
TocilizumabThe serum concentration of Eperisone can be decreased when it is combined with Tocilizumab.Approved
TofisopamThe risk or severity of adverse effects can be increased when Tofisopam is combined with Eperisone.Approved
TolazolineThe risk or severity of hypotension can be increased when Tolazoline is combined with Eperisone.Approved, Vet Approved
TolcaponeThe risk or severity of adverse effects can be increased when Tolcapone is combined with Eperisone.Approved, Withdrawn
ToloxatoneThe risk or severity of adverse effects can be increased when Toloxatone is combined with Eperisone.Approved
TolperisoneThe risk or severity of adverse effects can be increased when Eperisone is combined with Tolperisone.Approved, Investigational
TopiramateThe risk or severity of adverse effects can be increased when Topiramate is combined with Eperisone.Approved
TramadolThe risk or severity of adverse effects can be increased when Tramadol is combined with Eperisone.Approved, Investigational
TramiprosateThe risk or severity of adverse effects can be increased when Tramiprosate is combined with Eperisone.Investigational
TranylcypromineThe risk or severity of adverse effects can be increased when Tranylcypromine is combined with Eperisone.Approved, Investigational
TrazodoneThe risk or severity of adverse effects can be increased when Eperisone is combined with Trazodone.Approved, Investigational
TriazolamThe risk or severity of adverse effects can be increased when Triazolam is combined with Eperisone.Approved, Investigational
Tricaine methanesulfonateThe risk or severity of adverse effects can be increased when Tricaine methanesulfonate is combined with Eperisone.Vet Approved
TrichloroethyleneThe risk or severity of adverse effects can be increased when Trichloroethylene is combined with Eperisone.Approved
TriclofosThe risk or severity of adverse effects can be increased when Triclofos is combined with Eperisone.Withdrawn
TrifluoperazineThe risk or severity of hypotension can be increased when Trifluoperazine is combined with Eperisone.Approved, Investigational
TrifluperidolThe risk or severity of adverse effects can be increased when Trifluperidol is combined with Eperisone.Experimental
TriflupromazineThe risk or severity of adverse effects can be increased when Triflupromazine is combined with Eperisone.Approved, Vet Approved
TrimazosinThe risk or severity of hypotension can be increased when Trimazosin is combined with Eperisone.Experimental
TrimethadioneThe risk or severity of adverse effects can be increased when Trimethadione is combined with Eperisone.Approved
TrimipramineThe risk or severity of hypotension can be increased when Trimipramine is combined with Eperisone.Approved
TriprolidineThe risk or severity of adverse effects can be increased when Triprolidine is combined with Eperisone.Approved
TroleandomycinThe metabolism of Eperisone can be decreased when combined with Troleandomycin.Approved
TropisetronThe risk or severity of adverse effects can be increased when Eperisone is combined with Tropisetron.Approved, Investigational
TubocurarineEperisone may increase the neuromuscular blocking activities of Tubocurarine.Approved
UrapidilThe risk or severity of hypotension can be increased when Urapidil is combined with Eperisone.Investigational
VabicaserinThe risk or severity of adverse effects can be increased when Eperisone is combined with Vabicaserin.Investigational
ValerianThe risk or severity of adverse effects can be increased when Valerian is combined with Eperisone.Approved, Experimental, Investigational
ValnoctamideThe risk or severity of adverse effects can be increased when Valnoctamide is combined with Eperisone.Investigational
Valproic AcidThe risk or severity of adverse effects can be increased when Valproic Acid is combined with Eperisone.Approved, Investigational
ValpromideThe risk or severity of adverse effects can be increased when Valpromide is combined with Eperisone.Experimental
VancomycinThe risk or severity of adverse effects can be increased when Eperisone is combined with Vancomycin.Approved
VecuroniumEperisone may increase the neuromuscular blocking activities of Vecuronium.Approved
VemurafenibThe risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Eperisone.Approved
VenlafaxineThe risk or severity of adverse effects can be increased when Eperisone is combined with Venlafaxine.Approved
VeraliprideThe risk or severity of adverse effects can be increased when Veralipride is combined with Eperisone.Experimental
VerapamilThe risk or severity of hypotension can be increased when Verapamil is combined with Eperisone.Approved
VigabatrinThe risk or severity of adverse effects can be increased when Vigabatrin is combined with Eperisone.Approved
VilazodoneThe risk or severity of adverse effects can be increased when Vilazodone is combined with Eperisone.Approved
ViloxazineThe risk or severity of adverse effects can be increased when Viloxazine is combined with Eperisone.Approved, Investigational, Withdrawn
VinbarbitalThe risk or severity of adverse effects can be increased when Vinbarbital is combined with Eperisone.Experimental
VinpocetineThe risk or severity of adverse effects can be increased when Eperisone is combined with Vinpocetine.Investigational
Vinyl etherThe risk or severity of adverse effects can be increased when Vinyl ether is combined with Eperisone.Experimental
VinylbitalThe risk or severity of adverse effects can be increased when Vinylbital is combined with Eperisone.Experimental
VoriconazoleThe metabolism of Eperisone can be decreased when combined with Voriconazole.Approved, Investigational
VortioxetineThe risk or severity of adverse effects can be increased when Vortioxetine is combined with Eperisone.Approved, Investigational
WortmanninThe risk or severity of adverse effects can be increased when Eperisone is combined with Wortmannin.Experimental
XP19986The risk or severity of adverse effects can be increased when Eperisone is combined with XP19986.Investigational
XylazineThe risk or severity of adverse effects can be increased when Xylazine is combined with Eperisone.Vet Approved
YKP-1358The risk or severity of adverse effects can be increased when Eperisone is combined with YKP-1358.Investigational
YohimbineThe risk or severity of adverse effects can be increased when Eperisone is combined with Yohimbine.Approved, Investigational, Vet Approved
ZaleplonThe risk or severity of adverse effects can be increased when Zaleplon is combined with Eperisone.Approved, Illicit, Investigational
ZiconotideThe risk or severity of adverse effects can be increased when Ziconotide is combined with Eperisone.Approved
ZimelidineThe risk or severity of adverse effects can be increased when Eperisone is combined with Zimelidine.Withdrawn
ZiprasidoneThe risk or severity of hypotension can be increased when Ziprasidone is combined with Eperisone.Approved
ZolazepamThe risk or severity of adverse effects can be increased when Zolazepam is combined with Eperisone.Vet Approved
ZolmitriptanThe risk or severity of adverse effects can be increased when Eperisone is combined with Zolmitriptan.Approved, Investigational
ZolpidemEperisone may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.Approved
ZonisamideThe risk or severity of adverse effects can be increased when Zonisamide is combined with Eperisone.Approved, Investigational
ZopicloneThe risk or severity of adverse effects can be increased when Zopiclone is combined with Eperisone.Approved
ZotepineThe risk or severity of adverse effects can be increased when Zotepine is combined with Eperisone.Approved, Investigational, Withdrawn
ZuclopenthixolThe risk or severity of hypotension can be increased when Zuclopenthixol is combined with Eperisone.Approved, Investigational
Food Interactions
Not Available

References

General References
  1. Cabitza P, Randelli P: Efficacy and safety of eperisone in patients with low back pain: a double blind randomized study. Eur Rev Med Pharmacol Sci. 2008 Jul-Aug;12(4):229-35. [PubMed:18727454]
  2. Jeoung MK, Jeong ES, Kim NH, Kim CS, Chung YB, Lee YM, Ahn SY, Cho HE, Lee YH, Hong JT, Moon DC: Determination of eperisone in human plasma by liquid chromatography-ESI-tandem mass spectrometry. Arch Pharm Res. 2007 Sep;30(9):1174-8. [PubMed:17958338]
External Links
KEGG Drug
D01671
PubChem Compound
3236
PubChem Substance
310264953
ChemSpider
3123
ChEBI
77070
ChEMBL
CHEMBL1902981
Drugs.com
Drugs.com Drug Page
Wikipedia
Eperisone
ATC Codes
M03BX09 — Eperisone
MSDS
Download (138 KB)

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedTreatmentAcute Low Back Pain1
3CompletedTreatmentAcute Low Back Pain1
3CompletedTreatmentAcute Musculoskeletal Spasm Due to Low Back Pain1
3CompletedTreatmentMuscle Spasm; Back Pain1
Not AvailableCompletedTreatmentHealthy Volunteers1
Not AvailableRecruitingTreatmentLow Back Pain (LBP)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US3995047No1973-12-141993-03-11Us

Properties

State
Solid
Experimental Properties
PropertyValueSource
melting point (°C)170-172Morita, E. and Kanai,T.; U.S. Patent 3,995,047; November 30,1976; assigned to Eisai Co., Ltd. (Japan)
Predicted Properties
PropertyValueSource
Water Solubility0.0617 mg/mLALOGPS
logP4.27ALOGPS
logP4.01ChemAxon
logS-3.6ALOGPS
pKa (Strongest Acidic)16.34ChemAxon
pKa (Strongest Basic)8.77ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area20.31 Å2ChemAxon
Rotatable Bond Count5ChemAxon
Refractivity80.95 m3·mol-1ChemAxon
Polarizability31.74 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Download (35.3 KB)
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group.
Kingdom
Organic compounds
Super Class
Organic oxygen compounds
Class
Organooxygen compounds
Sub Class
Carbonyl compounds
Direct Parent
Alkyl-phenylketones
Alternative Parents
Phenylpropanes / Benzoyl derivatives / Aryl alkyl ketones / Piperidines / Beta-amino ketones / Trialkylamines / Azacyclic compounds / Organopnictogen compounds / Organic oxides / Hydrocarbon derivatives
Substituents
Alkyl-phenylketone / Phenylpropane / Benzoyl / Aryl alkyl ketone / Monocyclic benzene moiety / Beta-aminoketone / Piperidine / Benzenoid / Tertiary amine / Tertiary aliphatic amine
Molecular Framework
Aromatic heteromonocyclic compounds
External Descriptors
piperidines, aromatic ketone (CHEBI:77070)

Enzymes

Kind
Protein
Organism
Human
Pharmacological action
No
Actions
Substrate
General Function
Vitamin d3 25-hydroxylase activity
Specific Function
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation react...
Gene Name
CYP3A4
Uniprot ID
P08684
Uniprot Name
Cytochrome P450 3A4
Molecular Weight
57342.67 Da
References
  1. Uesawa Y, Takeuchi T, Mohri K: Integrated analysis on the physicochemical properties of dihydropyridine calcium channel blockers in grapefruit juice interactions. Curr Pharm Biotechnol. 2012 Jul;13(9):1705-17. [PubMed:22039822]

Drug created on June 11, 2014 13:41 / Updated on August 02, 2018 07:48