Displaying drugs 76 - 100 of 590 in total
Human Embryonic Stem Cell-derived M Cell
CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can be administered through injection. These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. These cells are currently being investigated against lung injury and fibrosis -- conditions which are...
Investigational
Matched Synonyms: … immunity- and matrix-regulatory cells ... Immunity-and-matrix-regulatory cells …
Matched Description: … anti-fibrotic functions, and being stronger in potential treatment of lung injury and fibrosis. ... CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can ... These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. …
Matched Description: … anti-fibrotic functions, and being stronger in potential treatment of lung injury and fibrosis. ... CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can ... These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. …
4-(Isopropylamino)diphenylamine
4-(Isopropylamino)diphenylamine, also known as IPPD, is a chemical compound commonly used as an antiozonant in rubbers, particularly those used for tires. It is also a known allergen. Sensitivity to this compound may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … N-Fenyl-N'-isopropyl-p-fenylendiamin ... N-Isopropyl-N'-phenyl-p-phenylenediamine ... N-Isopropyl-N'-phenyl-1,4-phenylenediamine …
Carmustine
A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985)....
Approved
Investigational
Matched Description: … It is used in the treatment of brain tumors and various other malignant neoplasms. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … BiCNU-100MG (CARMUSTINE FOR INJECTION USP 100MG) & DEHYDRATED ALCOHOL INJECTION USP AS A COMBIPACK …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … BiCNU-100MG (CARMUSTINE FOR INJECTION USP 100MG) & DEHYDRATED ALCOHOL INJECTION USP AS A COMBIPACK …
Vayarin
Vayarin is a prescription medical food for the clinical dietary management of certain lipid imbalances blamed to be associated with attention deficit hyperactivity disorder (ADHD) in children. Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. Vayarin is currently available only...
Approved
Investigational
Matched Synonyms: … Phosphatidylserine, DHA, and EPA …
Matched Description: … Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and ... Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure ... Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional …
Matched Description: … Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and ... Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure ... Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional …
Trifluoroethanol
A non-aqueous co-solvent that serves as tool to study protein folding. It is also used in various pharmaceutical, chemical and engineering applications.
Experimental
Matched Synonyms: … 2,2,2-trifluoroethyl alcohol …
Matched Description: … It is also used in various pharmaceutical, chemical and engineering applications. …
Matched Categories: … Alcohols …
Matched Description: … It is also used in various pharmaceutical, chemical and engineering applications. …
Matched Categories: … Alcohols …
Vatreptacog alfa
Vatreptacog Alfa (Activated) has been used in trials studying the treatment of Haemophilia B, Haemophilia A, Congenital Bleeding Disorder, Haemophilia A With Inhibitors, and Haemophilia B With Inhibitors.
Investigational
Matched Synonyms: … Vatreptacog alfa (activated) …
Matched Name: … Vatreptacog alfa …
Matched Description: … Vatreptacog Alfa (Activated) has been used in trials studying the treatment of Haemophilia B, Haemophilia ... A, Congenital Bleeding Disorder, Haemophilia A With Inhibitors, and Haemophilia B With Inhibitors. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Name: … Vatreptacog alfa …
Matched Description: … Vatreptacog Alfa (Activated) has been used in trials studying the treatment of Haemophilia B, Haemophilia ... A, Congenital Bleeding Disorder, Haemophilia A With Inhibitors, and Haemophilia B With Inhibitors. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Dornase alfa
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Dornasa alfa ... Dornase alfa ... Dornase alfa, recombinant …
Matched Name: … Dornase alfa …
Matched Description: … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. …
Matched Categories: … dornase alfa (desoxyribonuclease) ... Enzymes and Coenzymes ... Cough and Cold Preparations ... Amino Acids, Peptides, and Proteins …
Matched Name: … Dornase alfa …
Matched Description: … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. …
Matched Categories: … dornase alfa (desoxyribonuclease) ... Enzymes and Coenzymes ... Cough and Cold Preparations ... Amino Acids, Peptides, and Proteins …
Velmanase alfa
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Synonyms: … Velmanase alfa ... Velmanase alfa-tycv …
Matched Name: … Velmanase alfa …
Matched Description: … deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... [L45295] Velmanase alfa is currently not approved in Canada. …
Matched Categories: … velmanase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Name: … Velmanase alfa …
Matched Description: … deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... [L45295] Velmanase alfa is currently not approved in Canada. …
Matched Categories: … velmanase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Etafedrine
Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined with other drugs in the brand names Nethaprin and Dalmacol . It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis (now Sanofi) has been discontinued .
Ethylephedrine is...
Approved
Matched Synonyms: … alpha-(1-(ethylmethylamino)ethyl)benzyl alcohol …
Matched Description: … with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. ... Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined ... It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis …
Matched Categories: … Alcohols ... Amino Alcohols …
Matched Description: … with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. ... Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined ... It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis …
Matched Categories: … Alcohols ... Amino Alcohols …
Interferon alfa-n3
Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Approved
Investigational
Matched Synonyms: … Interferon alfa-n3 …
Matched Name: … Interferon alfa-n3 …
Matched Description: … for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and …
Matched Categories: … Alfa Interferons ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Interferon alfa-n3 …
Matched Description: … for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and …
Matched Categories: … Alfa Interferons ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Damoctocog alfa pegol
In recent years, various extended half-life factor VIII and factor IX preparations have been studied and gained approval. In order to extend half-lives, techniques such as fusion to protein conjugates (Fc part of IgG1 or albumin), chemical modification (PEGylation), and protein sequence modification have been utilized. Also known as, BAY94-9027,...
Approved
Investigational
Matched Synonyms: … Damoctocog alfa pegol …
Matched Name: … Damoctocog alfa pegol …
Matched Description: … [A38907] Also known as, BAY94-9027, Damoctocog alfa pegol is a longer-acting Factor VIII therapy formulated ... and gained approval. ... has been filed with the FDA in August 2017 and FDA approved in August 2018. …
Matched Name: … Damoctocog alfa pegol …
Matched Description: … [A38907] Also known as, BAY94-9027, Damoctocog alfa pegol is a longer-acting Factor VIII therapy formulated ... and gained approval. ... has been filed with the FDA in August 2017 and FDA approved in August 2018. …
Eftilagimod alfa
Eftilagimod alfa is under investigation in clinical trial NCT02614833 (IMP321 (Eftilagimod Alpha) as Adjunctive to a Standard Chemotherapy Paclitaxel Metastatic Breast Carcinoma).
Investigational
Matched Synonyms: … Eftilagimod alfa …
Matched Name: … Eftilagimod alfa …
Matched Description: … Eftilagimod alfa is under investigation in clinical trial NCT02614833 (IMP321 (Eftilagimod Alpha) as …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Costimulatory and Inhibitory T-Cell Receptors …
Matched Name: … Eftilagimod alfa …
Matched Description: … Eftilagimod alfa is under investigation in clinical trial NCT02614833 (IMP321 (Eftilagimod Alpha) as …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Costimulatory and Inhibitory T-Cell Receptors …
Methoxy polyethylene glycol-epoetin beta
Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
Approved
Matched Synonyms: … Pegzerepoetin alfa …
Matched Categories: … Alcohols ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Alcohols ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Baminercept
Investigational
Matched Synonyms: … Baminercept alfa …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Peginterferon alfa-2b
Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Synonyms: … Peginterferon alfa-2b …
Matched Name: … Peginterferon alfa-2b …
Matched Description: … Peginterferon alfa-2b is derived from the alfa-2b moeity of recombinant human interferon and acts by ... When combined together, Peginterferon alfa-2b and [Ribavirin] have been shown to achieve a SVR between ... aggravation and development of endocrine and autoimmune disorders, retinopathies, cardiovascular and …
Matched Categories: … Alcohols ... Alfa Interferons ... peginterferon alfa-2b ... Amino Acids, Peptides, and Proteins ... peginterferon alfa-2b, combinations …
Matched Name: … Peginterferon alfa-2b …
Matched Description: … Peginterferon alfa-2b is derived from the alfa-2b moeity of recombinant human interferon and acts by ... When combined together, Peginterferon alfa-2b and [Ribavirin] have been shown to achieve a SVR between ... aggravation and development of endocrine and autoimmune disorders, retinopathies, cardiovascular and …
Matched Categories: … Alcohols ... Alfa Interferons ... peginterferon alfa-2b ... Amino Acids, Peptides, and Proteins ... peginterferon alfa-2b, combinations …
Naphazoline
Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807].
Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Description: … It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations …
Matched Mixtures name: … COLLIRIO ALFA ANTISTAMINICO ... COLLIRIO ALFA ANTISTAMINICO ... Lubricant and Redness Reliever …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … COLLIRIO ALFA DECONGESTIONANTE …
Matched Mixtures name: … COLLIRIO ALFA ANTISTAMINICO ... COLLIRIO ALFA ANTISTAMINICO ... Lubricant and Redness Reliever …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … COLLIRIO ALFA DECONGESTIONANTE …
Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen
Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized ... allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular ... Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... developed as an alternative to autografting - the process by which a patient's own skin is harvested and …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular ... Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... developed as an alternative to autografting - the process by which a patient's own skin is harvested and …
Purvalanol A
Experimental
Matched Synonyms: … 2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine …
EDIT-301
EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2).
Investigational
Matched Synonyms: … Autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the HBG1 and HBG2 ... ) at the HBG1 and HBG2 promoters ... autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/Cas12a ribonucleoprotein (RNP …
Matched Description: … cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2). ... EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor …
Matched Description: … cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2). ... EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor …
Avalglucosidase alfa
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Synonyms: … Avalglucosidase alfa ... avalglucosidase alfa-ngpt …
Matched Name: … Avalglucosidase alfa …
Matched Description: … cellular uptake of the drug and better muscle targeting. ... , especially in smooth, cardiac, and skeletal muscle cells. ... Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe …
Matched Categories: … avalglucosidase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Name: … Avalglucosidase alfa …
Matched Description: … cellular uptake of the drug and better muscle targeting. ... , especially in smooth, cardiac, and skeletal muscle cells. ... Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe …
Matched Categories: … avalglucosidase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Cepeginterferon alfa-2B
Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Investigational
Matched Synonyms: … Cepeginterferon Alfa 2 B ... Cepeginterferon alfa-2B …
Matched Name: … Cepeginterferon alfa-2B …
Matched Description: … Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic ... Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative …
Matched Categories: … cepeginterferon alfa-2b ... Antineoplastic and Immunomodulating Agents …
Matched Name: … Cepeginterferon alfa-2B …
Matched Description: … Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic ... Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative …
Matched Categories: … cepeginterferon alfa-2b ... Antineoplastic and Immunomodulating Agents …
Displaying drugs 76 - 100 of 590 in total