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Displaying drugs 1101 - 1125 of 1215 in total

Olanzapine

Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Description: … and the absence of a chloride moiety. ... [A176996] The second-generation antipsychotics were introduced in the 90s and quickly gained traction ... due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Categories: … olanzapine and samidorphan ... Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … OLANZAPIN BASICS 5MG ... OLANZAPIN BASICS 10MG ... OLANZAPIN BASICS 15MG …

Amoxicillin

Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … Clavulin 125 F Oral Sus ... Clavulin 250 F Oral Sus ... Amoxicillin/Clav Pot Oral Susp …
Matched Categories: … Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... rabeprazole, amoxicillin and clarithromycin ... vonoprazan, amoxicillin and clarithromycin ... omeprazole, amoxicillin and rifabutin …
Matched Products: … Nu-amoxi Sus 125/5ml ... Nu-amoxi Sus 250mg/5ml ... Amox S 250 Sus 250mg/5ml …

Ersodetug

Investigational
Matched Synonyms: … Immunoglobulin G2, anti-(human insulin receptor) (human monoclonal RZ358 γ2-chain), disulfide with human …

Topotecan

An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TOPOTECAN POLVO LIOFILIZADO PARA INYECCION VIAL POR 4 MG …

Clervonafusp alfa

Investigational
Matched Synonyms: … -glucosidase (human recombinant), disulfide with humanized monoclonal 3e10 .kappa.-chain ... cell-penetrating humanized fab fragment targeting the equilibrative nucleoside transporter 2 (ent2), fused with a human …

Loncastuximab tesirine

Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through …
Matched Description: … and improve survival. ... refractory B-cell lymphoma is based on promising results from the LOTIS-2 clinical trial. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

RP-A501

RP-A501 is a gene therapy product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human LAMP2B transgene (AAV9:LAMP2B), which encodes lysosome-associated membrane protein 2 (LAMP-2). It is being investigated for Danon disease.
Investigational
Matched Synonyms: … Adeno-associated virus serotype 9 vector containing the human lysosome-associated membrane glycoprotein …
Matched Description: … product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human …

Tirabrutinib

Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS-4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)).
Investigational
Matched Synonyms: … ONO-4059 (free base) …
Matched Description: … 4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)). ... Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS- …

Inolimomab

Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immunologic Factors …

Sertraline

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before...
Approved
Matched Description: … is similar to drugs such as [Citalopram] and [Fluoxetine]. ... popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and ... classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and …
Matched Products: … SERTRALIN BASICS 50MG ... SERTRALIN BASICS 100MG …

Orlistat

The global prevalence of obesity is increasing rapidly. Obesity-related complications lead to significant personal and economic burden by reducing quality of life and increasing the cost of healthcare. In some individuals, diet and exercise are insufficient to maintain weight loss, and pharmacological or surgical intervention is required. Orlistat is a...
Approved
Investigational
Matched Description: … In some individuals, diet and exercise are insufficient to maintain weight loss, and pharmacological ... life and increasing the cost of healthcare. ... [L11130] This drug is a generally well-tolerated and effective weight-loss aid and is now available in …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … SOGRAS CAPSULA POR 120MG …

Efavirenz

Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Description: … ) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency ... Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI ... For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with …
Matched Mixtures name: … Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate ... Efavirenz, Lamivudine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... lamivudine, tenofovir disoproxil and efavirenz ... emtricitabine, tenofovir disoproxil and efavirenz ... Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor …
Matched Products: … EFAVAX ® TABLETAS RECUBIERTAS POR 600MG …

Lirentelimab

Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN SIALIC ACID-BINDINGE IG-LIKE LECTIN 8) (HUMAN-MUS MUSCULUS MONOCLONAL ... AK002 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL AK002 .KAPPA. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Strimvelis

Investigational
Matched Synonyms: … enriched cell fraction that contains CD34+ cells transduced with retroviral vector that encodes for the human …

Efocipegtrutide

Efocipegtrutide is a long-acting, monomeric peptide triple agonist.
Investigational
Matched Synonyms: … GLUCAGON ANALOG CONJUGATED WITH HUMAN IMMUNOGLOBULIN G4 FRAGMENT ... IMMUNOGLOBULIN G4 (HUMAN .GAMMA.4-CHAIN C REGION C-TERMINAL FRAGMENT), DIMER, 1-(1-(3-HYDROXYPROPYL)- …

Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine

The Covifenz COVID-19 vaccine (plant-based virus-like particles (VLP), recombinant, adjuvanted) is a plant-based vaccine developed in partnership by Medicago and GlaxoSmithKline which is approved in Canada for the prevention of COVID-19. It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and is mixed with...
Approved
Matched Name: … Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine …
Matched Description: … plant-based vaccine developed in partnership by Medicago and GlaxoSmithKline which is approved in Canada ... speed and ease of manufacturing and increased immunogenicity. ... composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and …

Levocetirizine

Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of cetirizine. Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine. Levocetirizine was granted FDA approval in 1995.
Approved
Matched Categories: … Cetirizine and isomer …
Matched Products: … Basic Care Allergy Relief …

Vincristine

Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate...
Approved
Investigational
Matched Description: … several brand names, many of which have different formulations such as Marqibo (liposomal injection) and ... indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and ... part of polychemotherapy because of lack of significant bone–marrow suppression (at recommended doses) and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … VINCRISTINA 1 MG POR 1 FRASCO …

Zalifrelimab

Zalifrelimab is under investigation in clinical trial NCT03894215 (Phase 2 Study of Anti-pd-1 Independently or in Combination With Anti-ctla-4 in Second-line Cervical Cancer).
Investigational
Matched Synonyms: … A human monoclonal antibody targeting cytotoxic T lymphocyte associated protein 4 (ctla4) …

Propofol

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Description: … for induction and/or maintenance of anaesthesia prior to and during surgeries. ... Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia ... effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … NIRFOL 1 % POR 10 ML ... CRIXOFOL 10MG/1MLAMPOLLA POR 20 ML …

Eptotermin alfa

A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Synonyms: … Human recombinant bone morphogenetic protein 7 …
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. …
Matched Categories: … Biological Factors ... Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization ... Intercellular Signaling Peptides and Proteins …

Crovalimab

Crovalimab is under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human complement c5)(humanized ro7112689 heavy chain), disulfide with humanized …
Matched Description: … under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and ... Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria …

Ocaratuzumab

Ocaratuzumab is a humanized monoclonal antibody directed against CD20. It is being investigated for cancers and autoimmune disorders.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1, Bp35, leukocyte …
Matched Description: … It is being investigated for cancers and autoimmune disorders. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

D-3082-L

D-3082-L is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.
Investigational
Matched Synonyms: … Human Papilloma Virus (HPV) Type 16 E6/e7 Synthetic Long Peptide (SLP) Vaccine Component D-3082-L …
Matched Description: … D-3082-L is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide …

Alglucosidase alfa

Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Synonyms: … Human acid precursor alpha-glucosidase, recombinant …
Matched Description: … Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of a-1,4- and a-1,6- glycosidic linkages ... It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. ... glycoprotein with a calculated mass of 98,008 daltons for the 883 residue mature polypeptide chain, and …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Displaying drugs 1101 - 1125 of 1215 in total