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Displaying drugs 13526 - 13550 of 13563 in total
Investigational
Matched Iupac: … 1-methyl-5-({2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl}oxy)-N-[4-(trifluoromethyl)phenyl]- ... 1H-1,3-benzodiazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Phenaridine (2,5-Dimethylfentanyl) is a synthetic fentanyl derivative opioid. It was developed in 1972, and is used for surgical anasthesia in Russia. Phenaridine has similar effects to fentanyl. In rat studies, it was less potent than fentanyl. Side effects include itching, nausea and serious to life threatening respiratory depression. Fentanyl analogs...
Illicit
Matched Iupac: … N-[2,5-dimethyl-1-(2-phenylethyl)piperidin-4-yl]-N-phenylpropanamide …
Matched Description: … Phenaridine (2,5-Dimethylfentanyl) is a synthetic fentanyl derivative opioid. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
PRLX 93936 is selectively toxic to cancer cells.
Investigational
Talarozole has been investigated for the treatment of Psoriasis and Cutaneous Inflammation.
Investigational
Matched Iupac: … N-{4-[2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl]phenyl}-1,3-benzothiazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Telcagepant has been investigated for the treatment of Migraine. It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide involved in the pathophysiology of migraine. CGRP and its receptors are found in areas of the central and peripheral nervous system that are important for the...
Investigational
Matched Iupac: … N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-{2-oxo-1H,2H,3H-imidazo ... [4,5-b]pyridin-1-yl}piperidine-1-carboxamide …
Matched Description: … It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Famprofazone is a nonsteroidal anti-inflammatory agent found in combination products such as ‘Gewodin’ which is marketed in Taiwan. It is important to note that the drug is metabolized to methamphetamine and amphetamine in the body and can lead to positive tests results for illicit drug use.[A236369,L34724] Famprofazone is included in...
Experimental
Matched Iupac: … 1-methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-4-(propan-2-yl)-2,3-dihydro-1H-pyrazol ... -3-one …
Matched Description: … Famprofazone is a nonsteroidal anti-inflammatory agent found in combination products such as ‘Gewodin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Mirfentanil is a derivative of fentanyl that presents high selectivity for the mu opioid receptor. At lower doses, it antagonizes the analgesic effects of alfentanil and substitutes for naloxone in morphine-treated monkeys; however, it also reverses naloxone-precipitated withdrawal in pigeons trained to discriminate morphine from naloxone. At high doses, it...
Experimental
Matched Iupac: … N-[1-(2-phenylethyl)piperidin-4-yl]-N-(pyrazin-2-yl)furan-2-carboxamide …
Matched Description: … Mirfentanil is a derivative of fentanyl that presents high selectivity for the mu opioid receptor. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … (2S)-2-(2-aminoacetamido)-4-carbamoylbutanoic acid …
Investigational
Matched Iupac: … (2R,3R,5S)-2-{5-amino-2-oxo-2H,3H-[1,3]thiazolo[4,5-d]pyrimidin-3-yl}-5-(hydroxymethyl)oxolan-3-yl acetate …
Investigational
Matched Iupac: … 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic …
Matched Salts cas: … 1400591-39-0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Bombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and Healthy Volunteers).
Investigational
Matched Iupac: … }butanamido]pentanamido]-4-methylpentanamido]acetamido}-3-carbamoylpropanamido]-N-[(1S)-1-{[(1S)-1-{[ ... (1S)-1-[({[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-3-(methylsulfanyl)propyl]carbamoyl}-3-methylbutyl]carbamoyl ... 1H-indol-3-yl)ethyl]pentanediamide ... (2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-5-carbamimidamido-2-[(2S)-4-carbamoyl-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido ... }-2-(1H-imidazol-4-yl)ethyl]carbamoyl}methyl)carbamoyl]-2-methylpropyl]carbamoyl}ethyl]carbamoyl}-2-( …
Matched Salts cas: … 33910-70-2
Vixotrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
Investigational
Matched Iupac: … (2S,5R)-5-{4-[(2-fluorophenyl)methoxy]phenyl}pyrrolidine-2-carboxamide …
Semapimod has been used in trials studying the treatment of Crohn Disease.
Investigational
Matched Iupac: … N,N'-bis({3,5-bis[(1E)-1-(carbamimidamidoimino)ethyl]phenyl})decanediamide …
Matched Salts cas: … 872830-80-3 ... 164301-51-3
PF-03187207 is a nitric oxide-donating prostaglandin F2-alpha analogs for the potential treatment of glaucoma. Based on the very promising preclinical results and on the well-known activities of nitric oxide, PF-03187207 is expected to have an increased capacity to reduce high IOP. The development of abnormally high IOP, due to blockage...
Investigational
Matched Description: … PF-03187207 is a nitric oxide-donating prostaglandin F2-alpha analogs for the potential treatment of …
Sesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic acid, stearic acid and other fatty acids. Sesame oil is reported to possess antioxidant, antiaging, antihypertensive, immunoregulatory and anticancer properties....
Investigational
Nutraceutical
Matched Description: … Sesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices …
LY517717 is an investigational oral direct inhibitor of activated Factor Xa. It is believed to be Lilly's PMD-3112 (licensed from Amgen).
Investigational
Matched Iupac: … N-[(1R)-2-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-2-oxo-1-phenylethyl]-1H-indole-6-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Lefradafiban is an oral platelet glycoprotein IIb/IIIa receptor antagonist being investigated in the treatment of angina.
Investigational
Matched Iupac: … oxopyrrolidin-3-yl]acetate ... methyl 2-[(3S,5S)-5-{[(4'-{[(methoxycarbonyl)amino]methanimidoyl}-[1,1'-biphenyl]-4-yl)oxy]methyl}-2- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
R-30490 is an opioid related to carfentanil used as an animal tranquilizer. It was first synthesized by Janssen Pharmaceutica as part of a structure-activity relationship study of fentanly and its derivatives. R-30490 was found to be the most selective agonist for the mu opioid receptor out of all the fentanyl...
Experimental
Matched Iupac: … N-[4-(methoxymethyl)-1-(2-phenylethyl)piperidin-4-yl]-N-phenylpropanamide …
Matched Description: … It was first synthesized by Janssen Pharmaceutica as part of a structure-activity relationship study …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … (2R,3S)-N'-hydroxy-N-[(1S)-1-(methylcarbamoyl)-2-phenylethyl]-2-(2-methylpropyl)-3-[(thiophen-2-ylsulfanyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Mitoguazone has been used in trials studying the treatment of Lymphoma, HIV Infections, and Lymphoma, Non-Hodgkin.
Investigational
Matched Iupac: … N''-[(E)-[(1E)-1-{[(diaminomethylidene)amino]imino}propan-2-ylidene]amino]guanidine …
Pyridoxamine has been used in trials studying the treatment of Kidney Stones.
Investigational
Matched Iupac: … 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol …
Matched Categories: … Vitamin B Complex ... Heterocyclic Compounds, 1-Ring …
DDP200 is developed by Dynogen for the treatment of non-incontinent form of overactive bladder (OAB) with particular focus on both male and female patients with urinary frequency, urinary urgency and nocturia.
Investigational
Experimental
Investigational
Matched Mixtures name: … Lyso-B Lozenges ... Lyso-B Oral Liquid …
Displaying drugs 13526 - 13550 of 13563 in total