Displaying drugs 1851 - 1875 of 2486 in total
nor-NOHA
N-Hydroxy-nor-L-arginine (nor-NOHA) is under investigation in clinical trial NCT02009527 (Arginase Inhibition in Ischemia-reperfusion Injury).
Investigational
Matched Synonyms: … (2S)-2-amino-4-(((hydroxyamino)iminomethyl)amino)butanoic acid …
Matched Iupac: … (2S)-2-amino-4-(N'-hydroxycarbamimidamido)butanoic acid …
Matched Iupac: … (2S)-2-amino-4-(N'-hydroxycarbamimidamido)butanoic acid …
1-Methylhistidine
Experimental
Matched Synonyms: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
Matched Iupac: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
N-methylnicotinamide
N-methylnicotinamide is an experimental drug with no approved indication or marketed formulation. It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by measuring N-methylnicotinamide in the urine.
Experimental
Matched Synonyms: … Nicotinic acid methylamide …
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Nicotinic Acids …
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Nicotinic Acids …
Mavodelpar
Investigational
Matched Synonyms: … REN-001 free acid …
Matched Iupac: … fluorophenyl)-3-{4-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}prop-2-en-1-yl]oxy}-2-methylphenoxy)acetic acid …
Matched Iupac: … fluorophenyl)-3-{4-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}prop-2-en-1-yl]oxy}-2-methylphenoxy)acetic acid …
Chloroprocaine
Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. The pharmacological profile of...
Approved
Investigational
Matched Synonyms: … 4-amino-2-chlorobenzoic acid 2-(diethylamino)ethyl ester …
Matched Description: … [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without ... formulation can be used for lumbar and caudal epidural blocks. ... increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid …
Matched Description: … [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without ... formulation can be used for lumbar and caudal epidural blocks. ... increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid …
RU85053
Experimental
Matched Synonyms: … Acetamido-3-oxo-3-[[(3S)-2-oxo-1-[(4-phenylphenyl)methyl]azepan-3-yl]amino]propyl]-2-(carboxymethyl)benzoic acid …
Matched Iupac: … [1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-(carboxymethyl)benzoic acid …
Matched Iupac: … [1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-(carboxymethyl)benzoic acid …
Acrivastine
Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and tachycardia.
Acrivastine is...
Approved
Matched Synonyms: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}acrylic acid …
Matched Iupac: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid …
Matched Description: … Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and …
Matched Iupac: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid …
Matched Description: … Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and …
Cianidanol
An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Approved
Withdrawn
Matched Synonyms: … Catechuic acid …
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
NP-51
Investigational
Matched Synonyms: … (+/-)-o-(3-piperidino-2-hydroxy-1-propyl)nicotinic acid amidoxime …
Vipoglanstat
Investigational
Matched Synonyms: … dimethyl-propionylamino)-methyl]-phenylamino}-6-(2,2-difluoroethoxy)-1-methyl-1H-benzoimidazole-5-carboxylic acid …
Perindopril
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Synonyms: … 3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid …
Matched Iupac: … 3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic acid …
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and ... be used to treat mild to moderate essential hypertension, mild to moderate congestive heart failure, and …
Matched Categories: … atorvastatin, acetylsalicylic acid and perindopril ... ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... perindopril and diuretics ... perindopril and bisoprolol …
Matched Iupac: … 3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic acid …
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and ... be used to treat mild to moderate essential hypertension, mild to moderate congestive heart failure, and …
Matched Categories: … atorvastatin, acetylsalicylic acid and perindopril ... ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... perindopril and diuretics ... perindopril and bisoprolol …
Levofloxacin
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Synonyms: … methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid ... dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid ... methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid …
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid …
Matched Description: … [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... lansoprazole, amoxicillin and levofloxacin ... Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid …
Matched Description: … [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... lansoprazole, amoxicillin and levofloxacin ... Metabolic Side Effects of Drugs and Substances …
N-2-Thiophen-2-Yl-Acetamide Boronic Acid
Experimental
Matched Name: … N-2-Thiophen-2-Yl-Acetamide Boronic Acid …
Matched Iupac: … {[2-(thiophen-2-yl)acetamido]methyl}boronic acid …
Matched Iupac: … {[2-(thiophen-2-yl)acetamido]methyl}boronic acid …
Vitamin B6 Complexed with 2-Amino-Hexanoic Acid
Experimental
Matched Name: … Vitamin B6 Complexed with 2-Amino-Hexanoic Acid …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]hexanoic acid …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]hexanoic acid …
Vitamin B6 Complexed with 2-Amino-Pentanoic Acid
Experimental
Matched Name: … Vitamin B6 Complexed with 2-Amino-Pentanoic Acid …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid …
2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid
Experimental
Matched Name: … 2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid …
Matched Iupac: … (2R)-2-[(N-hydroxyformamido)methyl]-4-methylpentanoic acid …
Matched Iupac: … (2R)-2-[(N-hydroxyformamido)methyl]-4-methylpentanoic acid …
2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID
Experimental
Matched Name: … 2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID …
Matched Iupac: … 2-hydroxy-5-[(2-sulfanylethyl)sulfamoyl]benzoic acid …
Matched Iupac: … 2-hydroxy-5-[(2-sulfanylethyl)sulfamoyl]benzoic acid …
(2S)-2-HYDROXY-2H-CHROMENE-2-CARBOXYLIC ACID
Experimental
Matched Name: … (2S)-2-HYDROXY-2H-CHROMENE-2-CARBOXYLIC ACID …
Matched Iupac: … (2S)-2-hydroxy-2H-chromene-2-carboxylic acid …
Matched Iupac: … (2S)-2-hydroxy-2H-chromene-2-carboxylic acid …
5-(dodecylthio)-1H-1,2,3-triazole-4-carboxylic acid
Experimental
Matched Name: … 5-(dodecylthio)-1H-1,2,3-triazole-4-carboxylic acid …
Matched Iupac: … 5-(dodecylsulfanyl)-1H-1,2,3-triazole-4-carboxylic acid …
Matched Iupac: … 5-(dodecylsulfanyl)-1H-1,2,3-triazole-4-carboxylic acid …
[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID
Experimental
Matched Name: … [(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID …
Matched Iupac: … [({[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy}carbamoyl)methyl]phosphonic acid …
Matched Iupac: … [({[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy}carbamoyl)methyl]phosphonic acid …
(2R)-3-{[(BENZYLAMINO)CARBONYL]AMINO}-2-HYDROXYPROPANOIC ACID
Experimental
Matched Name: … (2R)-3-{[(BENZYLAMINO)CARBONYL]AMINO}-2-HYDROXYPROPANOIC ACID …
Matched Iupac: … (2R)-3-[(benzylcarbamoyl)amino]-2-hydroxypropanoic acid …
Matched Iupac: … (2R)-3-[(benzylcarbamoyl)amino]-2-hydroxypropanoic acid …
3-BENZYLOXYCARBONYLAMINO-2-HYDROXY-4-PHENYL-BUTYRIC ACID
Experimental
Matched Name: … 3-BENZYLOXYCARBONYLAMINO-2-HYDROXY-4-PHENYL-BUTYRIC ACID …
Matched Iupac: … (2R,3S)-3-{[(benzyloxy)carbonyl]amino}-2-hydroxy-4-phenylbutanoic acid …
Matched Iupac: … (2R,3S)-3-{[(benzyloxy)carbonyl]amino}-2-hydroxy-4-phenylbutanoic acid …
2-((3'-TERTBUTYL-4'-HYDROXYPHENYL)AZO)BENZOIC ACID
Experimental
Matched Name: … 2-((3'-TERTBUTYL-4'-HYDROXYPHENYL)AZO)BENZOIC ACID …
Matched Iupac: … 2-[(1E)-2-(3-tert-butyl-4-hydroxyphenyl)diazen-1-yl]benzoic acid …
Matched Iupac: … 2-[(1E)-2-(3-tert-butyl-4-hydroxyphenyl)diazen-1-yl]benzoic acid …
N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID
Experimental
Matched Name: … N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID …
Displaying drugs 1851 - 1875 of 2486 in total