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Displaying drugs 1951 - 1975 of 2524 in total
Investigational
Matched Synonyms: … dimethyl-propionylamino)-methyl]-phenylamino}-6-(2,2-difluoroethoxy)-1-methyl-1H-benzoimidazole-5-carboxylic acid
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Synonyms: … 3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid
Matched Iupac: … 3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic acid
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and ... be used to treat mild to moderate essential hypertension, mild to moderate congestive heart failure, and
Matched Categories: … atorvastatin, acetylsalicylic acid and perindopril ... ACE Inhibitors and Diuretics ... perindopril and diuretics ... perindopril and bisoprolol ... perindopril and amlodipine …
Investigational
Matched Synonyms: … Cotsiranib tgf-.beta.1 si-rna free acid component ... Stp-705 component tgf-.beta.1 si-rna free acid ... Tgf-.beta.1 si-rna free acid component of cotsiranib …
Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Synonyms: … -HYDROXY-, 15-ETHER WITH N-ACETYL-L-LYSYL-L-VALYL-L-.ALPHA. ... N2-ACETYL-L-LYSYL-L-VALYL-L-.ALPHA.-GLUTAMYL-L-ARGINYL-L-PHENYLALANYL-L-.ALPHA. …
Matched Iupac: … 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72-tetracosaoxapentaheptacontan-75-amido}hexanoic acid
Matched Description: … Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … N-acetyl-acth(1-13)-amide ... Valinamide, acetyl-l-seryl-l-tyrosyl-l-seryl-l-methionyl-l-glutamyl-l-histidyl-l-phenylalanyl-l-arginyl-l-tryptophyl-glycyl-l-lysyl-l-prolyl …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Name: … 3-Methyl-5-Sulfo-Pyrrolidine-2-Carboxylic Acid
Matched Iupac: … (2R,3R,5S)-3-methyl-5-sulfopyrrolidine-2-carboxylic acid
Experimental
Matched Name: … 5-Hydroxyamino-3-Methyl-Pyrrolidine-2-Carboxylic Acid
Matched Iupac: … (2R,3R,5R)-5-(hydroxyamino)-3-methylpyrrolidine-2-carboxylic acid
Experimental
Matched Name: … 2-Amino-3-Oxo-4-Sulfo-Butyric Acid
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-3-(sulfooxy)propanoic acid
Experimental
Matched Name: … 3-(4-Benzenesulfonyl-Thiophene-2-Sulfonylamino)-Phenylboronic Acid
Matched Iupac: … {3-[4-(benzenesulfonyl)thiophene-2-sulfonamido]phenyl}boronic acid
Experimental
Matched Name: … 2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-3-(phosphonooxy)propanoic acid
Experimental
Matched Name: … 11-TRANS-13-TRANS-15-CIS-OCTADECATRIENOIC ACID
Matched Iupac: … (11E,13E,15Z)-octadeca-11,13,15-trienoic acid
Experimental
Matched Name: … (2S)-2-(1H-indol-3-yl)pentanoic acid
Matched Iupac: … (2S)-2-(1H-indol-3-yl)pentanoic acid
Experimental
Matched Name: … 5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID
Matched Iupac: … 5-(2-chloro-4-nitrophenyl)furan-2-carboxylic acid
Experimental
Matched Name: … (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid
Matched Iupac: … (2S)-2-{[1,1'-biphenyl]-4-yloxy}-3-phenylpropanoic acid
Experimental
Matched Name: … METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER …
Matched Iupac: … methyl(4-nitrophenoxy)phosphinic acid
Experimental
Matched Name: … 2-METHYLCARBAMOYL-3-(4-PHOSPHONOOXY-PHENYL)-CYCLOPROPANECARBOXYLIC ACID
Matched Iupac: … (1R,2R,3S)-2-(methylcarbamoyl)-3-[4-(phosphonooxy)phenyl]cyclopropane-1-carboxylic acid
Investigational
Matched Synonyms: … PHOSPHONIC ACID, (1-((((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)AMINO)ETHYL)-, DIETHYL ESTER ... PHOSPHONIC ACID, P-(1-((((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)AMINO)ETHYL)-, DIETHYL ESTER …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and skin structure infections. Community-acquired bacterial pneumonia.
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[4-(1-methylpyridin …
Matched Description: … treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and
Trioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative obtained from several plants, mainly Psoralea corylifolia. Like other psoralens it causes photosensitization of the skin. It is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of...
Approved
Matched Synonyms: … 6-hydroxy-β,2,7-trimethyl-5-benzofuranacrylic acid, δ-lactone …
Matched Description: … Trioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative ... In research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage ... conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo and
Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.
Investigational
Matched Synonyms: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
Matched Iupac: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
Matched Description: … Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Investigational
Matched Synonyms: … Internalized-arginylglycylaspartic acid cyclic peptide …
Desmopressin (dDAVP), a synthetic analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. ADH is an endogenous pituitary hormone that has a crucial role in the control of the water content in the body. Upon release from the...
Approved
Matched Synonyms: … 1-(3-mercaptopropionic acid)-8-D-arginine-vasopressin …
Matched Description: … solution, intravenous solution, oral tablet and oral lyophilisate [A31662]. ... a prolonged half-life and duration of action compared to endogenous ADH [A31661]. ... 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Synonyms: … 5'-Thymidylic acid, 3'-deoxy-3'-fluoro- …
Matched Iupac: … ,5R)-3-fluoro-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid
Experimental
Matched Synonyms: … carboxymethylamino)-3-[(R)-hydroxy-(N-hydroxy-4-iodoanilino)methyl]sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
Matched Iupac: … carboxymethyl)carbamoyl]-2-{[(R)-hydroxy[hydroxy(4-iodophenyl)amino]methyl]sulfanyl}ethyl]carbamoyl}butanoic acid
Experimental
Matched Synonyms: … N-[(S)-5-Amino-5-carboxypentyl]-L-glutamic acid
Matched Iupac: … (2S)-2-{[(5S)-5-amino-5-carboxypentyl]amino}pentanedioic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino …
Displaying drugs 1951 - 1975 of 2524 in total