Displaying drugs 2076 - 2100 of 2876 in total
Amiloxate
Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity .
Approved
Matched Synonyms: … 3-(4-Methoxyphenyl)-2-propenoic acid, 3-methylbutyl ester …
Matched Description: … Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916]. …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Description: … Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916]. …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Metrifonate
Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Vet approved
Matched Synonyms: … 1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester …
Matched Iupac: … dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate …
Matched Description: … It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Iupac: … dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate …
Matched Description: … It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Lesinurad
Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout. It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with...
Approved
Investigational
Matched Synonyms: … {[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Matched Iupac: … 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Matched Description: … of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with diuretic-induced ... In August 2017, a combination oral therapy consisting of lesinurad and [DB00437] was FDA-approved under ... Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Preparations Increasing Uric Acid Excretion …
Matched Iupac: … 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Matched Description: … of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with diuretic-induced ... In August 2017, a combination oral therapy consisting of lesinurad and [DB00437] was FDA-approved under ... Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Preparations Increasing Uric Acid Excretion …
Eflornithine
Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Synonyms: … (RS)-2,5-diamino-2-(difluoromethyl)pentanoic acid …
Matched Iupac: … 2,5-diamino-2-(difluoromethyl)pentanoic acid …
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and ... for the treatment of African trypanosomiasis and hirsutism, respectively, but has since been discontinued …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Agents Against Leishmaniasis and Trypanosomiasis ... Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents ... Antiparasitic Products, Insecticides and Repellents …
Matched Iupac: … 2,5-diamino-2-(difluoromethyl)pentanoic acid …
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and ... for the treatment of African trypanosomiasis and hirsutism, respectively, but has since been discontinued …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Agents Against Leishmaniasis and Trypanosomiasis ... Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents ... Antiparasitic Products, Insecticides and Repellents …
Bismuth subgallate
Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet...
Approved
Matched Synonyms: … gallic acid bismuth basic salt …
Matched Iupac: … 2,7-dihydroxy-2H-benzo[d]1,3-dioxa-2-bismacyclopentane-5-carboxylic acid …
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated ... antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter …
Matched Categories: … Antacids and Adsorbents ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Iupac: … 2,7-dihydroxy-2H-benzo[d]1,3-dioxa-2-bismacyclopentane-5-carboxylic acid …
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated ... antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter …
Matched Categories: … Antacids and Adsorbents ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
D-Tyrosine
A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.
Experimental
Matched Synonyms: … (R)-2-Amino-3-(p-hydroxyphenyl)propionic acid …
Matched Iupac: … (2R)-2-amino-3-(4-hydroxyphenyl)propanoic acid …
Matched Description: … It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. ... A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. …
Matched Iupac: … (2R)-2-amino-3-(4-hydroxyphenyl)propanoic acid …
Matched Description: … It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. ... A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. …
MG-S-2525
Investigational
Matched Synonyms: … 5-(3,5-Dimethyl-4-hydroxybenzylamino)-3-(4-morpholin-4-yl-phenylamino)-1H-pyrazole-4-carboxylic acid …
2-propenyl-N-acetyl-neuramic acid
Experimental
Matched Name: … 2-propenyl-N-acetyl-neuramic acid …
Matched Iupac: … 5R,6R)-5-acetamido-4-hydroxy-2-(prop-2-en-1-yl)-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
Matched Iupac: … 5R,6R)-5-acetamido-4-hydroxy-2-(prop-2-en-1-yl)-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
(R)-2-Hydroxy-3-Sulfopropanoic Acid
Experimental
Matched Name: … (R)-2-Hydroxy-3-Sulfopropanoic Acid …
Matched Iupac: … (2R)-2-hydroxy-3-sulfopropanoic acid …
Matched Iupac: … (2R)-2-hydroxy-3-sulfopropanoic acid …
3-deoxy-D-lyxo-hexonic acid
Experimental
Matched Name: … 3-deoxy-D-lyxo-hexonic acid …
Matched Iupac: … (2S,4R,5R)-2,4,5,6-tetrahydroxyhexanoic acid …
Matched Iupac: … (2S,4R,5R)-2,4,5,6-tetrahydroxyhexanoic acid …
3-(Phosphonomethyl)Pyridine-2-Carboxylic Acid
Experimental
Matched Name: … 3-(Phosphonomethyl)Pyridine-2-Carboxylic Acid …
Matched Iupac: … 3-(phosphonomethyl)pyridine-2-carboxylic acid …
Matched Iupac: … 3-(phosphonomethyl)pyridine-2-carboxylic acid …
2-(3-GUANIDINOPHENYL)-3-MERCAPTOPROPANOIC ACID
Experimental
Matched Name: … 2-(3-GUANIDINOPHENYL)-3-MERCAPTOPROPANOIC ACID …
Matched Iupac: … (2R)-2-{3-[(diaminomethylidene)amino]phenyl}-3-sulfanylpropanoic acid …
Matched Iupac: … (2R)-2-{3-[(diaminomethylidene)amino]phenyl}-3-sulfanylpropanoic acid …
5-(2-CHLOROBENZYL)-2-FUROIC ACID
Experimental
Matched Name: … 5-(2-CHLOROBENZYL)-2-FUROIC ACID …
Matched Iupac: … 5-[(2-chlorophenyl)methyl]furan-2-carboxylic acid …
Matched Iupac: … 5-[(2-chlorophenyl)methyl]furan-2-carboxylic acid …
2-((4'-HYDROXYPHENYL)-AZO)BENZOIC ACID
Experimental
Matched Name: … 2-((4'-HYDROXYPHENYL)-AZO)BENZOIC ACID …
Matched Iupac: … 2-[(1E)-2-(4-hydroxyphenyl)diazen-1-yl]benzoic acid …
Matched Iupac: … 2-[(1E)-2-(4-hydroxyphenyl)diazen-1-yl]benzoic acid …
4-(2-HYDROXYPHENYLTHIO)-1-BUTENYLPHOSPHONIC ACID
Experimental
Matched Name: … 4-(2-HYDROXYPHENYLTHIO)-1-BUTENYLPHOSPHONIC ACID …
Matched Iupac: … [(1E)-4-[(2-hydroxyphenyl)sulfanyl]but-1-en-1-yl]phosphonic acid …
Matched Iupac: … [(1E)-4-[(2-hydroxyphenyl)sulfanyl]but-1-en-1-yl]phosphonic acid …
(2S)-hydroxy(4-hydroxyphenyl)ethanoic acid
Experimental
Matched Name: … (2S)-hydroxy(4-hydroxyphenyl)ethanoic acid …
Matched Iupac: … (2S)-2-hydroxy-2-(4-hydroxyphenyl)acetic acid …
Matched Iupac: … (2S)-2-hydroxy-2-(4-hydroxyphenyl)acetic acid …
3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID
Experimental
Matched Name: … 3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID …
Matched Iupac: … 3-(4-sulfamoylphenyl)propanoic acid …
Matched Iupac: … 3-(4-sulfamoylphenyl)propanoic acid …
2-((4'-HYDROXYNAPHTHYL)-AZO)BENZOIC ACID
Experimental
Matched Name: … 2-((4'-HYDROXYNAPHTHYL)-AZO)BENZOIC ACID …
Matched Iupac: … 2-[(1E)-2-(4-hydroxynaphthalen-1-yl)diazen-1-yl]benzoic acid …
Matched Iupac: … 2-[(1E)-2-(4-hydroxynaphthalen-1-yl)diazen-1-yl]benzoic acid …
2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID
Experimental
Matched Name: … 2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID …
Matched Iupac: … 2-[(4-chlorophenyl)amino]pyridine-3-carboxylic acid …
Matched Iupac: … 2-[(4-chlorophenyl)amino]pyridine-3-carboxylic acid …
Candoxatril
Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
Experimental
Matched Synonyms: … 1H-Indeb5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]cyclohexanecarboxylic acid ... indan-5-yloxycarbonyl)-3-(2-methoxy-ethoxy)-propyl]-cyclopentanecarbonyl}-amino)-cyclohexanecarboxylic acid …
Matched Iupac: … 1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentaneamido}cyclohexane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … 1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentaneamido}cyclohexane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Ceftizoxime
A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Synonyms: … syn-7-(2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid ... Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … 1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … of both aerobic and anaerobic gram-positive and gram-negative organisms. ... It has few side effects and is reported to be safe and effective in aged patients and in patients with ... The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range …
Matched Iupac: … 1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … of both aerobic and anaerobic gram-positive and gram-negative organisms. ... It has few side effects and is reported to be safe and effective in aged patients and in patients with ... The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range …
Gatifloxacin
Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid ... 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid …
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. ... It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. ... Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. …
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. ... It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. ... Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. …
Methysergide
An ergot derivative that is a congener of lysergic acid diethylamide. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the...
Approved
Matched Synonyms: … 1-Methyllysergic acid butanolamide ... 1-Methyl-D-lysergic acid butanolamide ... 1-Methyl-dextro-lysergic acid (+)-1-hydroxy-2-butylamide …
Matched Description: … Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin ... It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has ... An ergot derivative that is a congener of lysergic acid diethylamide. …
Matched Categories: … Ergot Alkaloids and Derivatives ... Lysergic Acid …
Matched Description: … Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin ... It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has ... An ergot derivative that is a congener of lysergic acid diethylamide. …
Matched Categories: … Ergot Alkaloids and Derivatives ... Lysergic Acid …
Lisinopril
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched International brands: … Bellisin …
Matched Iupac: … (2S)-1-[(2S)-6-amino-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and ... [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. …
Matched Mixtures name: … Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Diuretics ... lisinopril and diuretics ... lisinopril and amlodipine …
Matched Iupac: … (2S)-1-[(2S)-6-amino-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and ... [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. …
Matched Mixtures name: … Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Diuretics ... lisinopril and diuretics ... lisinopril and amlodipine …
2,4-deoxy-4-guanidino-5-N-acetyl-neuraminic acid
Experimental
Matched Synonyms: … 5R,6R)-5-Acetamido-4-(diaminomethylideneamino)-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
Matched Name: … 2,4-deoxy-4-guanidino-5-N-acetyl-neuraminic acid …
Matched Iupac: … ,6R)-4-[(diaminomethylidene)amino]-5-acetamido-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
Matched Name: … 2,4-deoxy-4-guanidino-5-N-acetyl-neuraminic acid …
Matched Iupac: … ,6R)-4-[(diaminomethylidene)amino]-5-acetamido-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
Displaying drugs 2076 - 2100 of 2876 in total