Displaying drugs 4276 - 4300 of 5616 in total
6-(4-chloro-2-fluoro-3-phenoxybenzyl)pyridazin-3(2H)-one
Experimental
Matched Name: … 6-(4-chloro-2-fluoro-3-phenoxybenzyl)pyridazin-3(2H)-one …
Matched Iupac: … 6-[(4-chloro-2-fluoro-3-phenoxyphenyl)methyl]-2,3-dihydropyridazin-3-one …
Matched Iupac: … 6-[(4-chloro-2-fluoro-3-phenoxyphenyl)methyl]-2,3-dihydropyridazin-3-one …
Rivabazumab pegol
Rivabazumab pegol is being investigated as a treatment of Pseudomonas aeruginosa lung infections in patients with cystic fibrosis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN FAB' G1-KAPPA PEGYLATED, ANTI-PSEUDOMONAS AERUGINOSA TYPE III SECRETION SYSTEM (TTSS)PCRV PROTEIN …
Recifercept
Investigational
Matched Synonyms: … Human fibroblast growth factor receptor 3 (fgfr-3, cd333) (1-336)-(401-413) fragment (1-349) (soluble ... Recombinant human fibroblast growth factor receptor 3 ... Fibroblast growth factor receptor 3 (recombinant human soluble isoform ta-46) …
Pociredir
Investigational
Matched Synonyms: … -4-(2-methyl-3-pyridinyl)-, (7as)- ... 7h-furo(4,3,2-gh)(1,2,4)triazolo(4',3':1,6)pyrido(2,3-c)(5,2)benzoxazonine, 12-fluoro-7a,8,13,14-tetrahydro …
Matched Iupac: … (15S)-21-fluoro-10-(2-methylpyridin-3-yl)-13,17-dioxa-3,5,7,8-tetraazapentacyclo[13.6.1.0^{4,12}.0^{5,9 …
Matched Iupac: … (15S)-21-fluoro-10-(2-methylpyridin-3-yl)-13,17-dioxa-3,5,7,8-tetraazapentacyclo[13.6.1.0^{4,12}.0^{5,9 …
Lomustine
An alkylating agent of value against both hematologic malignancies and solid tumors.
Approved
Investigational
Matched Synonyms: … 1-(2-chloroethyl)-3-cyclohexylnitrosourea ... 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea …
Matched Iupac: … 3-(2-chloroethyl)-1-cyclohexyl-3-nitrosourea …
Matched Description: … An alkylating agent of value against both hematologic malignancies and solid tumors. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 3-(2-chloroethyl)-1-cyclohexyl-3-nitrosourea …
Matched Description: … An alkylating agent of value against both hematologic malignancies and solid tumors. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Rifapentine
Rifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.
Approved
Investigational
Matched Synonyms: … 3-(((4-Cyclopentyl-1-piperazinyl)imino)methyl)rifamycin …
Matched Iupac: … 8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^{5,28}]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl acetate …
Matched Salts name: … Rifapentine hydrochloride …
Matched Iupac: … 8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^{5,28}]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl acetate …
Matched Salts name: … Rifapentine hydrochloride …
Coenzyme A
Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, well known for it's role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of...
Investigational
Nutraceutical
Matched Synonyms: … 3'-phosphoadenosine-(5')diphospho(4')pantatheine …
Matched Iupac: … -3-yl]oxy}phosphonic acid ... {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl ... -3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan …
Matched Description: … of fatty acids, and the oxidation of pyruvate in the citric acid cycle. ... Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, well known for it's role in the synthesis and oxidation ... All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Enzymes and Coenzymes …
Matched Iupac: … -3-yl]oxy}phosphonic acid ... {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl ... -3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan …
Matched Description: … of fatty acids, and the oxidation of pyruvate in the citric acid cycle. ... Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, well known for it's role in the synthesis and oxidation ... All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Enzymes and Coenzymes …
(2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate
Experimental
Matched Synonyms: … 1-Octadecyl-2-acetamido-2-deoxy-SN-glycerol-3-phosphoethylmethyl sulfide …
Matched Name: … (2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate …
Matched Iupac: … [(2R)-2-acetamido-3-(octadecyloxy)propoxy][2-(methylsulfanyl)ethoxy]phosphinic acid …
Matched Name: … (2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate …
Matched Iupac: … [(2R)-2-acetamido-3-(octadecyloxy)propoxy][2-(methylsulfanyl)ethoxy]phosphinic acid …
Purvalanol A
Experimental
Matched Synonyms: … 2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine …
Matched Iupac: … (2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}amino)-3-methylbutan-1-ol …
Matched Categories: … CDC2 Protein Kinase, antagonists & inhibitors …
Matched Iupac: … (2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}amino)-3-methylbutan-1-ol …
Matched Categories: … CDC2 Protein Kinase, antagonists & inhibitors …
Rifalazil
Rifalazil is a derivative of the antibiotic rifamycin. It is being investigated by ActivBiotics for the treatment of various bacterial infections.
Investigational
Matched Synonyms: … 3'-hydroxy-5'-(4-isobutyl-1-piperazinyl)benzoxazinorifamycin …
Matched Iupac: … ),9,19,21,25,28,30,32,34-undecaen-13-yl acetate ... ,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,32-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-30 ... 8,27,38-trioxa-24,34-diazahexacyclo[23.11.1.1^{4,7}.0^{5,36}.0^{26,35}.0^{28,33}]octatriaconta-1,3,5(36 …
Matched Iupac: … ),9,19,21,25,28,30,32,34-undecaen-13-yl acetate ... ,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,32-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-30 ... 8,27,38-trioxa-24,34-diazahexacyclo[23.11.1.1^{4,7}.0^{5,36}.0^{26,35}.0^{28,33}]octatriaconta-1,3,5(36 …
Phenylalanylamide
Experimental
Matched Synonyms: … (S)-2-amino-3-phenylpropanamide …
Matched Iupac: … (2S)-2-amino-3-phenylpropanamide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … (2S)-2-amino-3-phenylpropanamide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Mirococept
Mirococept (APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and I/RI. It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct that regulates the over-production of complement at the cell surface, which occurs in inflammation. It consists...
Investigational
Matched Synonyms: … myristoylated recombinant SCR1-3 of human complement reseptor type I …
Matched Description: … APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and ... short consensus domains of human complement receptor 1 (CR1), manufactured in recombinant bacteria and …
Matched Description: … APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and ... short consensus domains of human complement receptor 1 (CR1), manufactured in recombinant bacteria and …
Imolamine
Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3-phenyl-4,5-dihydro-1,2,3-oxadiazol,-4-yl)ethyl]amine. It is developed under the brand name Coremax by Novartis consumer health SA.
Investigational
Matched Synonyms: … 3-Phenyl-4-diethylaminoethyl-5-imino-1,2,4-oxadiazol …
Matched Iupac: … diethyl[2-(5-imino-3-phenyl-4,5-dihydro-1,2,4-oxadiazol-4-yl)ethyl]amine …
Matched Description: … Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3- …
Matched Salts name: … Imolamine hydrochloride …
Matched Iupac: … diethyl[2-(5-imino-3-phenyl-4,5-dihydro-1,2,4-oxadiazol-4-yl)ethyl]amine …
Matched Description: … Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3- …
Matched Salts name: … Imolamine hydrochloride …
3-amino-1-chloro-4-phenyl-butanol-2-yl
Experimental
Matched Synonyms: … (2R,3S)-3-amino-1-chloro-4-phenylbutan-2-ol …
Matched Name: … 3-amino-1-chloro-4-phenyl-butanol-2-yl …
Matched Iupac: … (2R,3S)-3-amino-1-chloro-4-phenylbutan-2-ol …
Matched Name: … 3-amino-1-chloro-4-phenyl-butanol-2-yl …
Matched Iupac: … (2R,3S)-3-amino-1-chloro-4-phenylbutan-2-ol …
2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol
Experimental
Matched Synonyms: … 1,4:3,6-Dianhydro-2,5-bis-O-(3-carbamimidoylphenyl)-D-glucitol …
Matched Name: … 2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol …
Matched Iupac: … 3-{[(3R,3aR,6S,6aR)-6-(3-carbamimidoylphenoxy)-hexahydrofuro[3,2-b]furan-3-yl]oxy}benzene-1-carboximidamide …
Matched Name: … 2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol …
Matched Iupac: … 3-{[(3R,3aR,6S,6aR)-6-(3-carbamimidoylphenoxy)-hexahydrofuro[3,2-b]furan-3-yl]oxy}benzene-1-carboximidamide …
Valopicitabine
The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Synonyms: … 2'-C-methylcytidine 3'-O-L-valinyl ester …
Matched Iupac: … 3-yl (2S)-2-amino-3-methylbutanoate ... (2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan- …
Matched Description: … This blocks viral production of HCV RNA and thus viral replication. [from NCI] ... upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and ... The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … 3-yl (2S)-2-amino-3-methylbutanoate ... (2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan- …
Matched Description: … This blocks viral production of HCV RNA and thus viral replication. [from NCI] ... upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and ... The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Avotaciclib
Avotaciclib is under investigation in clinical trial NCT03579836 (Evaluation of Safety and Efficacy in BEY1107 in Monotherapy Gemcitabine Combination in Patient With Pancreatic Cancer).
Investigational
Matched Synonyms: … 2,6-bis(2-aminopyrimidin-4-yl)pyridin-3-ol …
Matched Iupac: … 2,6-bis(2-aminopyrimidin-4-yl)pyridin-3-ol …
Matched Description: … Avotaciclib is under investigation in clinical trial NCT03579836 (Evaluation of Safety and Efficacy in …
Matched Iupac: … 2,6-bis(2-aminopyrimidin-4-yl)pyridin-3-ol …
Matched Description: … Avotaciclib is under investigation in clinical trial NCT03579836 (Evaluation of Safety and Efficacy in …
(3r)-1-Acetyl-3-Methylpiperidine
Experimental
Matched Name: … (3r)-1-Acetyl-3-Methylpiperidine …
Matched Iupac: … 1-[(3R)-3-methylpiperidin-1-yl]ethan-1-one …
Matched Iupac: … 1-[(3R)-3-methylpiperidin-1-yl]ethan-1-one …
4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline
Experimental
Matched Name: … 4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline …
Matched Iupac: … 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol …
Matched Iupac: … 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol …
3-methyl-benzene-1,2-diol
3-methyl-benzene-1,2-diol is a solid. This compound belongs to the catechols. These are compounds containing a 1,2-benzenediol moeity. 3-methyl-benzene-1,2-diol targets the protein biphenyl-2,3-diol 1,2-dioxygenase.
Experimental
Matched Name: … 3-methyl-benzene-1,2-diol …
Matched Iupac: … 3-methylbenzene-1,2-diol …
Matched Description: … These are compounds containing a 1,2-benzenediol moeity. 3-methyl-benzene-1,2-diol targets the protein ... 3-methyl-benzene-1,2-diol is a solid. This compound belongs to the catechols. …
Matched Iupac: … 3-methylbenzene-1,2-diol …
Matched Description: … These are compounds containing a 1,2-benzenediol moeity. 3-methyl-benzene-1,2-diol targets the protein ... 3-methyl-benzene-1,2-diol is a solid. This compound belongs to the catechols. …
GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE
Experimental
Matched Name: … GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE …
Matched Iupac: … 3,4-d][1,3]dioxol-2-yl]phosphonic acid ... [(2S,3aR,4R,6R,6aR)-4-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-6-(hydroxymethyl)-tetrahydro-2H-furo[ …
Matched Iupac: … 3,4-d][1,3]dioxol-2-yl]phosphonic acid ... [(2S,3aR,4R,6R,6aR)-4-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-6-(hydroxymethyl)-tetrahydro-2H-furo[ …
N-(3-MERCAPTOPROPANOYL)-D-ALANINE
Experimental
Matched Name: … N-(3-MERCAPTOPROPANOYL)-D-ALANINE …
Matched Iupac: … (2R)-2-(3-sulfanylpropanamido)propanoic acid …
Matched Iupac: … (2R)-2-(3-sulfanylpropanamido)propanoic acid …
9-(3-IODOBENZYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE
Experimental
Matched Name: … 9-(3-IODOBENZYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE …
Matched Iupac: … N-[(3-iodophenyl)methyl]-1,2,3,4-tetrahydroacridin-9-amine …
Matched Iupac: … N-[(3-iodophenyl)methyl]-1,2,3,4-tetrahydroacridin-9-amine …
3-AMINO-AZACYCLOTRIDECAN-2-ONE
Experimental
Matched Name: … 3-AMINO-AZACYCLOTRIDECAN-2-ONE …
Matched Iupac: … (3S)-3-amino-1-azacyclotridecan-2-one …
Matched Iupac: … (3S)-3-amino-1-azacyclotridecan-2-one …
Displaying drugs 4276 - 4300 of 5616 in total