Displaying drugs 4401 - 4425 of 11433 in total
Tianeptine
Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) . Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological properties than typical tricyclic antidepressants .
Tianeptine was discovered and...
Investigational
Matched Description: … Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied ... Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Gold Au-198
Experimental
MM-111
MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Investigational
Matched Description: … MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor …
MVA-BN-brachyury-TRICOM vaccine
MVA-BN-brachyury-TRICOM vaccine is an investigational cancer vaccine. It is composed of recombinant vaccinia viral vector, modified vaccinia Ankara-Bavarian Nordic (MVA-BN), encoding the human transcription factor and tumour-associated antigen (TAA) brachyury, and a triad of T-cell co-stimulatory molecules (TRICOM), which is comprised of the three human immune-enhancing co-stimulatory molecules B7-1, ICAM-1...
Investigational
Matched Description: … co-stimulatory molecules B7-1, ICAM-1 and LFA-3. ... MVA-BN), encoding the human transcription factor and tumour-associated antigen (TAA) brachyury, and a ... [L44513] MVA-BN-brachyury-TRICOM vaccine is administered as a priming vaccine, followed by the administration …
BEA-17
BEA-17 is a small molecule targeted degrader of the epigenetic enzyme LSD1 and its co-factor CoREST. It is under investigation for the treatment of glioblastoma.
Investigational
Matched Description: … BEA-17 is a small molecule targeted degrader of the epigenetic enzyme LSD1 and its co-factor CoREST. …
Xylose-Derived Imidazole
Experimental
Matched Iupac: … (6R,7S,8S)-5H,6H,7H,8H-imidazo[1,2-a]pyridine-6,7,8-triol …
Cetilistat
Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.
Investigational
Matched Description: … obesity and associated co-morbidities, including type 2 diabetes. ... Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of …
Resveratrol
Resveratrol (3,5,4'-trihydroxystilbene) is a polyphenolic phytoalexin. It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. It exists as cis-(Z) and trans-(E) isomers. The trans- form can undergo isomerisation to the cis- form when heated or exposed to ultraviolet...
Investigational
Matched Description: … It has been claimed that it is readily degraded by exposure to light, heat, and oxygen. ... In a 2004 issue of Science, Dr. ... It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene …
Matched Mixtures name: … Co-Balamin ... Co-Veratrol …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … Co-Balamin ... Co-Veratrol …
Matched Categories: … Compounds used in a research, industrial, or household setting …
INCB-9471
INCB-9471 is a novel, orally available CCR5 antagonist that is part of a new class of drugs to treat HIV/AIDS. It is a potent, selective inhibitor of the HIV-1 virus.
Investigational
Matched Description: … INCB-9471 is a novel, orally available CCR5 antagonist that is part of a new class of drugs to treat ... It is a potent, selective inhibitor of the HIV-1 virus. …
mRNA-3927
mRNA-3927 is an investigational mRNA therapy that consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA carboxylase (PCC) encapsulated within a lipid nanoparticle (LNP). Developed by Moderna Inc., it is being investigated for the treatment of propionic acidemia.
Investigational
Matched Description: … carboxylase (PCC) encapsulated within a lipid nanoparticle (LNP). ... consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA …
Phenacetin
Phenacetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy (damage to or disease of the kidney).
Withdrawn
PAC-1
PAC-1 has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Cancers, among others.
Investigational
Presatovir
Presatovir has been used in trials studying the treatment of RSV Infection, Respiratory Syncytial Virus (RSV), Respiratory Syncytial Virus Infections, and Respiratory Syncytial Virus (RSV) Infections.
Investigational
Matched Iupac: … N-{2-[(2S)-2-{5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl}piperidine-1-carbonyl …
Trapidil
Trapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease.
Experimental
Matched Iupac: … N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine …
Matched Description: … Trapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and …
Matched Description: … Trapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and …
Corticorelin acetate
Corticorelin acetate has been investigated for the treatment of Brain Edema and Brain Tumor.
Investigational
AG0301-COVID19
AG0301-COVID19 is a vaccine candidate developed by AnGes Inc. and Osaka University. The candidate is a plasmid DNA vaccine developed using an intradermal gene transfer method targeting the SARS-CoV-2 spike protein. The gene transfer method increases the efficiency of gene expression and antibody production capability, garnering a more efficient DNA...
Investigational
Matched Description: … AG0301-COVID19 is a vaccine candidate developed by AnGes Inc. and Osaka University. ... The candidate is a plasmid DNA vaccine developed using an intradermal gene transfer method targeting ... transfer method increases the efficiency of gene expression and antibody production capability, garnering a …
AG0302-COVID19
Sponsored by Anges, Inc. in Japan, the AG0302-COVID19 is a DNA-based vaccine that recently completed Phase I/II trials (NCT04527081)[A226813, L30548].
Investigational
Matched Description: … Sponsored by Anges, Inc. in Japan, the AG0302-COVID19 is a DNA-based vaccine that recently completed …
Autologous cord blood
Investigational
Tavapadon
Tavapadon is under investigation in clinical trial NCT02262767 (A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of PF-06649751 Co-administered With Trimethobenzamide Hydrochloride in Healthy Subjects).
Investigational
Matched Description: … , and Pharmacokinetics of PF-06649751 Co-administered With Trimethobenzamide Hydrochloride in Healthy ... Tavapadon is under investigation in clinical trial NCT02262767 (A Study to Investigate the Safety, Tolerability …
PIKA rabies vaccine
PIKA rabies vaccine is a novel vaccine developed by YS Biopharma.
Investigational
Matched Description: … PIKA rabies vaccine is a novel vaccine developed by YS Biopharma. …
2-Aminophenol
Experimental
M-Cresol
Experimental
Duroquinone
Experimental
Coelenteramide
Experimental
Displaying drugs 4401 - 4425 of 11433 in total