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Displaying drugs 101 - 125 of 590 in total
Efanesoctocog alfa
Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding episodes in patients with hemophilia A. The use of FVIII replacement products is beneficial in patients with hemophilia A; however, their quality...
Approved
Investigational
Matched Name: … Efanesoctocog alfa …
Matched Description: … [A257464] Efanesoctocog alfa was designed to have an extended half-life, and to surpass the half-life ... To extend the half-life of FVIII, efanesoctocog alfa is fused to dimeric Fc, a D'D3 domain of VWF, and ... routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … [A257464] Efanesoctocog alfa was designed to have an extended half-life, and to surpass the half-life ... To extend the half-life of FVIII, efanesoctocog alfa is fused to dimeric Fc, a D'D3 domain of VWF, and ... routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tividenofusp alfa
Tividenofusp alfa, also known as DNL-310, is a brain-penetrant enzyme replacement therapy being investigated for the treatment of Hunter syndrome.
Investigational
Matched Name: … Tividenofusp alfa …
Matched Description: … Tividenofusp alfa, also known as DNL-310, is a brain-penetrant enzyme replacement therapy being investigated …
Matched Description: … Tividenofusp alfa, also known as DNL-310, is a brain-penetrant enzyme replacement therapy being investigated …
Talactoferrin alfa
Talactoferrin alfa is a novel immunomodulatory 80 kD protein with demonstrated oral anti-tumor properties. Lactoferrin, a protein found in breast milk is developed by Agennix. It increases body’s immune power and also works as a natural antioxidant, helping to control cell and tissue damage caused by oxidation.
Investigational
Matched Synonyms: … Talactoferrin alfa …
Matched Name: … Talactoferrin alfa …
Matched Description: … It increases body’s immune power and also works as a natural antioxidant, helping to control cell and ... Talactoferrin alfa is a novel immunomodulatory 80 kD protein with demonstrated oral anti-tumor properties …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Name: … Talactoferrin alfa …
Matched Description: … It increases body’s immune power and also works as a natural antioxidant, helping to control cell and ... Talactoferrin alfa is a novel immunomodulatory 80 kD protein with demonstrated oral anti-tumor properties …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Lesinidase alfa
Lesinidase alfa is under investigation in clinical trial NCT02324049 (Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 in Mucopolysaccharidosis III, Type B (MPS IIIB)).
Investigational
Matched Synonyms: … Lesinidase alfa …
Matched Name: … Lesinidase alfa …
Matched Description: … Lesinidase alfa is under investigation in clinical trial NCT02324049 (Safety, Pharmacokinetics, and Pharmacodynamics …
Matched Name: … Lesinidase alfa …
Matched Description: … Lesinidase alfa is under investigation in clinical trial NCT02324049 (Safety, Pharmacokinetics, and Pharmacodynamics …
Cepeginterferon alfa-2B
Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Investigational
Matched Synonyms: … Cepeginterferon Alfa 2 B ... Cepeginterferon alfa-2B …
Matched Name: … Cepeginterferon alfa-2B …
Matched Description: … Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic ... Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative …
Matched Categories: … cepeginterferon alfa-2b ... Antineoplastic and Immunomodulating Agents …
Matched Name: … Cepeginterferon alfa-2B …
Matched Description: … Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic ... Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative …
Matched Categories: … cepeginterferon alfa-2b ... Antineoplastic and Immunomodulating Agents …
Avalglucosidase alfa
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Synonyms: … Avalglucosidase alfa ... avalglucosidase alfa-ngpt …
Matched Name: … Avalglucosidase alfa …
Matched Description: … cellular uptake of the drug and better muscle targeting. ... , especially in smooth, cardiac, and skeletal muscle cells. ... Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe …
Matched Categories: … avalglucosidase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Name: … Avalglucosidase alfa …
Matched Description: … cellular uptake of the drug and better muscle targeting. ... , especially in smooth, cardiac, and skeletal muscle cells. ... Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe …
Matched Categories: … avalglucosidase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Etafedrine
Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined with other drugs in the brand names Nethaprin and Dalmacol . It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis (now Sanofi) has been discontinued .
Ethylephedrine is...
Approved
Matched Synonyms: … alpha-(1-(ethylmethylamino)ethyl)benzyl alcohol …
Matched Description: … with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. ... Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined ... It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis …
Matched Categories: … Alcohols ... Amino Alcohols …
Matched Description: … with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. ... Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined ... It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis …
Matched Categories: … Alcohols ... Amino Alcohols …
Tapinarof
Tapinarof is a novel, first-in-class, small-molecule AhR agonist that is indicated for the treatment of adult psoriasis. It is available as a topical cream to be applied to the affected area once daily.[L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) produced in Photorhabdus luminescens, a gram-negative bacillus that...
Approved
Investigational
Matched Synonyms: … 3,5-Dihydroxy-4-isopropyl-trans-stilbene …
Carmustine
A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985)....
Approved
Investigational
Matched Description: … It is used in the treatment of brain tumors and various other malignant neoplasms. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … BiCNU-100MG (CARMUSTINE FOR INJECTION USP 100MG) & DEHYDRATED ALCOHOL INJECTION USP AS A COMBIPACK …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … BiCNU-100MG (CARMUSTINE FOR INJECTION USP 100MG) & DEHYDRATED ALCOHOL INJECTION USP AS A COMBIPACK …
Vayarin
Vayarin is a prescription medical food for the clinical dietary management of certain lipid imbalances blamed to be associated with attention deficit hyperactivity disorder (ADHD) in children. Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. Vayarin is currently available only...
Approved
Investigational
Matched Synonyms: … Phosphatidylserine, DHA, and EPA …
Matched Description: … Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and ... Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure ... Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional …
Matched Description: … Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and ... Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure ... Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional …
Purvalanol A
Experimental
Matched Synonyms: … 2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine …
Human Embryonic Stem Cell-derived M Cell
CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can be administered through injection. These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. These cells are currently being investigated against lung injury and fibrosis -- conditions which are...
Investigational
Matched Synonyms: … immunity- and matrix-regulatory cells ... Immunity-and-matrix-regulatory cells …
Matched Description: … anti-fibrotic functions, and being stronger in potential treatment of lung injury and fibrosis. ... CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can ... These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. …
Matched Description: … anti-fibrotic functions, and being stronger in potential treatment of lung injury and fibrosis. ... CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can ... These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. …
Marzeptacog alfa (activated)
Marzeptacog alfa (activated) is under investigation in clinical trial NCT01439971 (Phase 1 Safety, Pharmacokinetics And Pharmacodynamics Study Of Recombinant Factor VIIa Variant (813d) In Adult Subjects With Hemophilia).
Investigational
Matched Synonyms: … Marzeptacog alfa (activated) …
Matched Name: … Marzeptacog alfa (activated) …
Matched Description: … And Pharmacodynamics Study Of Recombinant Factor VIIa Variant (813d) In Adult Subjects With Hemophilia ... Marzeptacog alfa (activated) is under investigation in clinical trial NCT01439971 (Phase 1 Safety, Pharmacokinetics …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Name: … Marzeptacog alfa (activated) …
Matched Description: … And Pharmacodynamics Study Of Recombinant Factor VIIa Variant (813d) In Adult Subjects With Hemophilia ... Marzeptacog alfa (activated) is under investigation in clinical trial NCT01439971 (Phase 1 Safety, Pharmacokinetics …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Phenol
Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products...
Approved
Experimental
Matched Synonyms: … Phenyl alcohol ... Phenylic alcohol …
Matched Description: … Phenol is an antiseptic and disinfectant. ... Phenol has been used to disinfect skin and to relieve itching. ... It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly …
Matched Mixtures name: … Major Camphor and Phenol ... Poison Oak and Ivy ... CAMPHOR (SYNTHETIC) and PHENOL …
Matched Categories: … Phenol and Derivatives ... Antiseptics and Disinfectants …
Matched Description: … Phenol is an antiseptic and disinfectant. ... Phenol has been used to disinfect skin and to relieve itching. ... It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly …
Matched Mixtures name: … Major Camphor and Phenol ... Poison Oak and Ivy ... CAMPHOR (SYNTHETIC) and PHENOL …
Matched Categories: … Phenol and Derivatives ... Antiseptics and Disinfectants …
Turoctocog alfa pegol
Turoctocog alfa pegol is a pegylated version of turoctocog alfa. Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019.
Fundamentally, the N8-GP moiety is identical to turoctocog alfa, a recombinant human clotting factor VIII (rFVIII) with a truncated B-domain made...
Approved
Matched Synonyms: … Turoctocog alfa pegol ... Turoctocog alfa pegol, N8-GP …
Matched Name: … Turoctocog alfa pegol …
Matched Description: … The essential difference between turoctocog alfa and N8-GP, however, is the specific attachment of a ... Turoctocog alfa pegol is a pegylated version of [turoctocog alfa]. ... It was developed by Novo Nordisk and approved by the US FDA on October 16, 2013 [L1104]. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Turoctocog alfa pegol …
Matched Description: … The essential difference between turoctocog alfa and N8-GP, however, is the specific attachment of a ... Turoctocog alfa pegol is a pegylated version of [turoctocog alfa]. ... It was developed by Novo Nordisk and approved by the US FDA on October 16, 2013 [L1104]. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Choriogonadotropin alfa
Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical...
Approved
Matched Synonyms: … Choriogonadotropin alfa …
Matched Name: … Choriogonadotropin alfa …
Matched Description: … O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER ... -121, SER-127, SER-132 and SER-138 (on beta subunit). ... human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and …
Matched Categories: … choriogonadotropin alfa ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …
Matched Name: … Choriogonadotropin alfa …
Matched Description: … O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER ... -121, SER-127, SER-132 and SER-138 (on beta subunit). ... human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and …
Matched Categories: … choriogonadotropin alfa ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …
Taliglucerase alfa
Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase. It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's disease.
Approved
Investigational
Matched Synonyms: … Taliglucerase alfa …
Matched Name: … Taliglucerase alfa …
Matched Description: … Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase ... It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's …
Matched Categories: … taliglucerase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Name: … Taliglucerase alfa …
Matched Description: … Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase ... It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's …
Matched Categories: … taliglucerase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Conestat alfa
C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Synonyms: … Conestat alfa …
Matched Name: … Conestat alfa …
Matched Description: … tPA and plasmin within the fibrinolytic pathway. ... Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. ... The primary function of endogenous C1INH is to regulate the activation of the complement and contact …
Matched Categories: … conestat alfa ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Name: … Conestat alfa …
Matched Description: … tPA and plasmin within the fibrinolytic pathway. ... Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. ... The primary function of endogenous C1INH is to regulate the activation of the complement and contact …
Matched Categories: … conestat alfa ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Susoctocog alfa
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … Susoctocog alfa …
Matched Name: … Susoctocog alfa …
Matched Description: … Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for ... Susoctocog alfa is a glycoprotein containing a 90 kDa heavy chain and a 80 kDa light chain with the naturally-occuring ... These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this …
Matched Categories: … susoctocog alfa ... Blood and Blood Forming Organs …
Matched Name: … Susoctocog alfa …
Matched Description: … Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for ... Susoctocog alfa is a glycoprotein containing a 90 kDa heavy chain and a 80 kDa light chain with the naturally-occuring ... These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this …
Matched Categories: … susoctocog alfa ... Blood and Blood Forming Organs …
Efmoroctocog alfa
Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as DB13999 . It is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It...
Approved
Investigational
Matched Synonyms: … Efmoroctocog alfa …
Matched Name: … Efmoroctocog alfa …
Matched Description: … Other drug products with similar structure and function to Efmoroctocog alfa include [DB13999], which ... Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life ... is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. …
Matched Name: … Efmoroctocog alfa …
Matched Description: … Other drug products with similar structure and function to Efmoroctocog alfa include [DB13999], which ... Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life ... is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. …
Beroctocog alfa
Approved
Investigational
Matched Name: … Beroctocog alfa …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pegvorhyaluronidase alfa
Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Investigational
Matched Synonyms: … Pegvorhyaluronidase alfa ... (36-482)-PEPTIDE (MATURE (1-447)-PEPTIDE), PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ALFA …
Matched Name: … Pegvorhyaluronidase alfa …
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single ... Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection). …
Matched Categories: … Enzymes and Coenzymes …
Matched Name: … Pegvorhyaluronidase alfa …
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single ... Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection). …
Matched Categories: … Enzymes and Coenzymes …
Pabinafusp alfa
Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Investigational
Matched Synonyms: … Pabinafusp alfa ... receptor 1, tfr1) humanized monoclonal antibody, fused with human iduronate-2-sulfatase, glycoform alfa …
Matched Name: … Pabinafusp alfa …
Matched Description: … Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With …
Matched Categories: … pabinafusp alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Name: … Pabinafusp alfa …
Matched Description: … Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With …
Matched Categories: … pabinafusp alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Alunacedase alfa
Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities.
Investigational
Matched Synonyms: … Alunacedase alfa …
Matched Name: … Alunacedase alfa …
Matched Description: … Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. ... This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Name: … Alunacedase alfa …
Matched Description: … Alunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. ... This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Displaying drugs 101 - 125 of 590 in total