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Displaying drugs 151 - 175 of 590 in total
Poractant alfa
Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. It is used to treat Respiratory Distress Syndrome (RDS) in premature infants with an endogenous pulmonary surfactant deficiency. Poractant alfa is an extract of natural porcine lung surfactant consisting of 99% polar lipids (mainly phospholipids)...
Approved
Matched Name: … Poractant alfa …
Matched Description: … Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. ... and SP-C). ... Poractant alfa is a creamy white suspension of this extract in 0.9% sodium chloride solution. …
Matched Description: … Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. ... and SP-C). ... Poractant alfa is a creamy white suspension of this extract in 0.9% sodium chloride solution. …
Antithrombin Alfa
Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention of thromboembolic events in patients that have hereditary deficiency of antithrombin in high risk situations.
Approved
Investigational
Matched Synonyms: … Antithrombin Alfa …
Matched Name: … Antithrombin Alfa …
Matched Description: … Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention …
Matched Name: … Antithrombin Alfa …
Matched Description: … Antithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention …
Thrombin alfa
Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human thrombin. Thrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically...
Approved
Matched Synonyms: … Thrombin alfa …
Matched Name: … Thrombin alfa …
Matched Description: … Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human ... The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious ... and the placebo treatment in patient subjects, thrombin alfa is not currently approved by certain organizations …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Name: … Thrombin alfa …
Matched Description: … Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human ... The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious ... and the placebo treatment in patient subjects, thrombin alfa is not currently approved by certain organizations …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Eftrenonacog alfa
Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H)...
Approved
Investigational
Matched Synonyms: … Eftrenonacog alfa …
Matched Name: … Eftrenonacog alfa …
Matched Description: … Eftrenonacog alfa was developed and marketed as Alprolix for intravenous injection by Biogen. ... Eftrenonacog alfa acts as a replacement therapy to restore the levels of factor IX and allow normal hemostasis ... Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Name: … Eftrenonacog alfa …
Matched Description: … Eftrenonacog alfa was developed and marketed as Alprolix for intravenous injection by Biogen. ... Eftrenonacog alfa acts as a replacement therapy to restore the levels of factor IX and allow normal hemostasis ... Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Eptotermin alfa
A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Synonyms: … Eptotermin alfa ... Eptotermina alfa …
Matched Name: … Eptotermin alfa …
Matched Description: … Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft. ... It is both a potent osteogenic factor and a specific regulator of nephrogenesis. …
Matched Categories: … eptotermin alfa ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Name: … Eptotermin alfa …
Matched Description: … Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft. ... It is both a potent osteogenic factor and a specific regulator of nephrogenesis. …
Matched Categories: … eptotermin alfa ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Dibotermin alfa
Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. It is implanted in patients undergoing bone surgeries or those with fractures. BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions on the...
Approved
Investigational
Matched Synonyms: … Dibotermin alfa ... Dibotermina alfa …
Matched Name: … Dibotermin alfa …
Matched Description: … In 2004, it was approved by the FDA and is marketed as Infuse. ... Dibotermin alfa was approved by the EMA in 2002 as Inductos for implantation matrix. ... Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant …
Matched Categories: … dibotermin alfa ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Name: … Dibotermin alfa …
Matched Description: … In 2004, it was approved by the FDA and is marketed as Infuse. ... Dibotermin alfa was approved by the EMA in 2002 as Inductos for implantation matrix. ... Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant …
Matched Categories: … dibotermin alfa ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Cerliponase alfa
Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. It was the first FDA-approved treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl...
Approved
Investigational
Matched Synonyms: … Cerliponase alfa …
Matched Name: … Cerliponase alfa …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and ... Cerliponase alfa was approved in April, 2017 (as Brineura). ... Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. …
Matched Categories: … cerliponase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Name: … Cerliponase alfa …
Matched Description: … treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and ... Cerliponase alfa was approved in April, 2017 (as Brineura). ... Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. …
Matched Categories: … cerliponase alfa ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Simlukafusp alfa
RO6874281 is under investigation in clinical trial NCT03193190 (A Study of Multiple Immunotherapy-based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-pancreatic Cancer)).
Investigational
Matched Name: … Simlukafusp alfa …
Efavaleukin alfa
Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker. It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease).
Investigational
Matched Synonyms: … Efavaleukin alfa …
Matched Name: … Efavaleukin alfa …
Matched Description: … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With ... Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin …
Matched Name: … Efavaleukin alfa …
Matched Description: … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With ... Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin …
Talditercept alfa
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … Taldefgrobep alfa ... Talditercept alfa …
Matched Name: … Talditercept alfa …
Matched Description: … Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the ... Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy) …
Matched Name: … Talditercept alfa …
Matched Description: … Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the ... Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy) …
Eflepedocokin alfa
Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant region (IgG2-Fc).[A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).
Investigational
Matched Name: … Eflepedocokin alfa …
Matched Description: … Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Efprezimod alfa
CD24Fc is a biological immunomodulator originally developed to address graft-versus-host disease in stem cell transplantation in leukemia patients.
Investigational
Matched Synonyms: … Human CD24 and human IgG Fc Fusion Protein …
Matched Name: … Efprezimod alfa …
Matched Name: … Efprezimod alfa …
Bucelipase alfa
Bucelipase alfa is under investigation in clinical trial NCT00743483 (Efficacy of Bucelipase Alfa (BSSL) in Patients With Cystic Fibrosis and Pancreatic Insufficiency).
Investigational
Matched Name: … Bucelipase alfa …
Matched Description: … ) in Patients With Cystic Fibrosis and Pancreatic Insufficiency). ... Bucelipase alfa is under investigation in clinical trial NCT00743483 (Efficacy of Bucelipase Alfa (BSSL …
Matched Description: … ) in Patients With Cystic Fibrosis and Pancreatic Insufficiency). ... Bucelipase alfa is under investigation in clinical trial NCT00743483 (Efficacy of Bucelipase Alfa (BSSL …
Tralesinidase alfa
Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Synonyms: … Tralesinidase alfa …
Matched Name: … Tralesinidase alfa …
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Tralesinidase alfa …
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Eftansomatropin alfa
Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Eftansomatropin alfa …
Matched Name: … Eftansomatropin alfa …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Eftansomatropin alfa …
Matched Description: … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Lusacomfar Alfa
Lusacomfar Alfa is a recombinant complement factor H
Investigational
Matched Name: … Lusacomfar Alfa …
Matched Description: … Lusacomfar Alfa is a recombinant complement factor H …
Matched Description: … Lusacomfar Alfa is a recombinant complement factor H …
Zelpultide alfa
Zelpultide alfa is a recombinant human surfactant protein D.
Investigational
Matched Synonyms: … PROTEIN D), NON-COVALENT QUADRUPLE TRIMER, PRODUCED IN HUMAN MYELOGENOUS LEUKEMIA K562 CELLS, GLYCOFORME ALFA …
Matched Name: … Zelpultide alfa …
Matched Description: … Zelpultide alfa is a recombinant human surfactant protein D. …
Matched Name: … Zelpultide alfa …
Matched Description: … Zelpultide alfa is a recombinant human surfactant protein D. …
Efbemalenograstim alfa
Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration.[L48852,A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant G-CSF like efbemalenograstim...
Approved
Matched Name: … Efbemalenograstim alfa …
Matched Description: … the production of neutrophils and thus reducing the severity and duration of neutropenia. ... Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating ... GC-627-05 in the US and Europe respectively. …
Matched Categories: … efbemalenograstim alfa ... Antineoplastic and Immunomodulating Agents …
Matched Description: … the production of neutrophils and thus reducing the severity and duration of neutropenia. ... Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating ... GC-627-05 in the US and Europe respectively. …
Matched Categories: … efbemalenograstim alfa ... Antineoplastic and Immunomodulating Agents …
Nogapendekin alfa
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Inbakicept nogapendekin alfa fusion complex ... Fusion protein consisting of il-15n72d and il-15rasu/fc …
Matched Name: … Nogapendekin alfa …
Matched Description: … Nogapendekin alfa is a human IL-15N72D variant. ... stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which also ... product also containing [inbakicept], where a single inbakicept is complexed with two nogapendekin alfa …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Nogapendekin alfa …
Matched Description: … Nogapendekin alfa is a human IL-15N72D variant. ... stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which also ... product also containing [inbakicept], where a single inbakicept is complexed with two nogapendekin alfa …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Interferon alfa
Natural interferon alpha or Multiferon is obtained from the leukocyte fraction of human blood following induction with Sendai virus. Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography. Interferon alpha proteins are mainly involved in innate immune response against viral infection. They come in 13...
Investigational
Matched Synonyms: … Interferon alfa …
Matched Name: … Interferon alfa …
Matched Description: … Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography ... Of these, IFN-α2 and IFN-α14 are glycosylated. ... Multiferon consists of the 6 major subtypes are IFN-α1, IFN-α2, IFN-α8, IFN-α10, IFN-α14 and IFN-α21. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Interferon alfa …
Matched Description: … Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography ... Of these, IFN-α2 and IFN-α14 are glycosylated. ... Multiferon consists of the 6 major subtypes are IFN-α1, IFN-α2, IFN-α8, IFN-α10, IFN-α14 and IFN-α21. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Coagulation factor VIIa Recombinant Human
Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Synonyms: … Eptacog alfa ... Eptacog alfa (activated) …
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … powder and solvent for solution for injection 2mg ... powder and solvent for solution for injection 1mg ... NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … powder and solvent for solution for injection 2mg ... powder and solvent for solution for injection 1mg ... NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
S,R-Warfarin alcohol
Experimental
Matched Name: … S,R-Warfarin alcohol …
Matched Categories: … Warfarin and isomers …
Matched Categories: … Warfarin and isomers …
Displaying drugs 151 - 175 of 590 in total