Cloning and sequencing of the cDNA encoding human glutaredoxin.
Article Details
- CitationCopy to clipboard
Fernando MR, Sumimoto H, Nanri H, Kawabata S, Iwanaga S, Minakami S, Fukumaki Y, Takeshige K
Cloning and sequencing of the cDNA encoding human glutaredoxin.
Biochim Biophys Acta. 1994 Jun 21;1218(2):229-31.
- PubMed ID
- 8018729 [ View in PubMed]
- Abstract
Glutaredoxin (thioltransferase) is a small, heat-stable protein, which is involved in thiol/disulfide exchange reactions. We have isolated a cDNA that encodes glutaredoxin from a human brain cDNA library. The encoded protein contains 106 amino acids with a calculated molecular mass of 11.76 kDa and an isoelectric point of 8.09. The amino acid sequence deduced from the cDNA is more than 80% identical to those of other mammalian glutaredoxins.