| Pathway Name | Drugs | SMPDB ID |
|---|---|---|
| ACE Inhibitors | ||
| Benazepril Pathway |
Benazepril |
SMP00145 |
| Captopril Pathway |
Captopril |
SMP00146 |
| Cilazapril Pathway |
Cilazapril |
SMP00147 |
| Enalapril Pathway |
Enalapril |
SMP00148 |
| Fosinopril Pathway |
Fosinopril |
SMP00149 |
| Lisinopril Pathway |
Lisinopril |
SMP00150 |
| Moexipril Pathway |
Moexipril |
SMP00151 |
| Perindopril Pathway |
Perindopril |
SMP00152 |
| Quinapril Pathway |
Quinapril |
SMP00153 |
| Ramipril Pathway |
Ramipril |
SMP00154 |
| Rescinnamine Pathway |
Rescinnamine |
SMP00155 |
| Spirapril Pathway |
Spirapril |
SMP00156 |
| Trandolapril Pathway |
Trandolapril |
SMP00157 |
| Alkylating Agents | ||
| Cyclophosphamide Pathway |
Cyclophosphamide |
SMP00447 |
| Ifosfamide Pathway |
Ifosfamide |
SMP00448 |
| Anti-EGFR Monoclonal Antibodies | ||
| Cetuximab Pathway |
Cetuximab |
SMP00474 |
| Panitumumab Pathway |
Panitumumab |
SMP00475 |
| Trastuzumab Pathway |
Trastuzumab |
SMP00476 |
| Anti-EGFR Tyrosine Kinase Inhibitors | ||
| Erlotinib Pathway |
Erlotinib |
SMP00472 |
| Gefitinib Pathway |
Gefitinib |
SMP00473 |
| Antiarrhythmic Agents | ||
| Disopyramide Pathway |
Disopyramide |
SMP00325 |
| Flecainide Pathway |
Flecainide |
SMP00331 |
| Fosphenytoin (Antiarrhythmic) Pathway |
Fosphenytoin Phenytoin |
SMP00326 |
| Ibutilide Pathway |
Ibutilide |
SMP00332 |
| Lidocaine (Antiarrhythmic) Pathway |
Lidocaine |
SMP00328 |
| Mexiletine Pathway |
Mexiletine |
SMP00329 |
| Phenytoin (Antiarrhythmic) Pathway |
Phenytoin |
SMP00327 |
| Procainamide (Antiarrhythmic) Pathway |
Procainamide |
SMP00324 |
| Quinidine Pathway |
Quinidine |
SMP00323 |
| Tocainide Pathway |
Tocainide |
SMP00330 |
| Antibiotics, Aminoglycosides | ||
| Amikacin Pathway |
Amikacin |
SMP00253 |
| Gentamicin Pathway |
Gentamicin |
SMP00254 |
| Kanamycin Pathway |
Kanamycin |
SMP00255 |
| Neomycin Pathway |
Neomycin |
SMP00256 |
| Netilmicin Pathway |
Netilmicin |
SMP00257 |
| Streptomycin Pathway |
Streptomycin |
SMP00259 |
| Antibiotics, Macrolides | ||
| Azithromycin Pathway |
Azithromycin |
SMP00247 |
| Clarithromycin Pathway |
Clarithromycin |
SMP00248 |
| Erythromycin Pathway |
Erythromycin |
SMP00250 |
| Roxithromycin Pathway |
Roxithromycin |
SMP00251 |
| Telithromycin Pathway |
Telithromycin |
SMP00252 |
| Antibiotics, Miscellaneous | ||
| Clindamycin Pathway |
Clindamycin |
SMP00249 |
| Spectinomycin Pathway |
Spectinomycin |
SMP00258 |
| Antibiotics, Tetracyclines | ||
| Clomocycline Pathway |
Clomocycline |
SMP00262 |
| Demeclocycline Pathway |
Demeclocycline |
SMP00290 |
| Doxycycline Pathway |
Doxycycline |
SMP00291 |
| Lymecycline Pathway |
Lymecycline |
SMP00295 |
| Minocycline Pathway |
Minocycline |
SMP00292 |
| Oxytetracycline Pathway |
Oxytetracycline |
SMP00293 |
| Tetracycline Pathway |
Tetracycline |
SMP00294 |
| Antifibrinolytic Agents | ||
| Aminocaproic Acid Pathway |
Aminocaproic Acid |
SMP00286 |
| Aprotinin Pathway |
Aprotinin |
SMP00288 |
| Tranexamic Acid Pathway |
Tranexamic Acid |
SMP00287 |
| Antimuscarinic Agents | ||
| Pirenzepine Pathway |
Pirenzepine |
SMP00246 |
| Antineoplastic Agents, Fluoropyrimidine Analogues | ||
| Capecitabine Pathway |
Capecitabine Fluorouracil |
SMP00469 |
| Fluorouracil Pathway |
Fluorouracil |
SMP00470 |
| Antineoplastic Agents, Nucleoside Analogues | ||
| Gemcitabine Pathway |
Gemcitabine |
SMP00446 |
| Antineoplastic Agents, Other | ||
| Irinotecan Pathway |
Irinotecan |
SMP00433 |
| Antineoplastic Agents, Vinca Alkaloids | ||
| Vinblastine Pathway |
Vinblastine |
SMP00436 |
| Vincristine Pathway |
Vincristine |
SMP00437 |
| Vindesine Pathway |
Vindesine |
SMP00438 |
| Vinorelbine Pathway |
Vinorelbine |
SMP00439 |
| Beta-blockers | ||
| Acebutolol Pathway |
Acebutolol |
SMP00296 |
| Alprenolol Pathway |
Alprenolol |
SMP00297 |
| Atenolol Pathway |
Atenolol |
SMP00298 |
| Betaxolol Pathway |
Betaxolol |
SMP00299 |
| Bisoprolol Pathway |
Bisoprolol |
SMP00300 |
| Carvedilol Pathway |
Carvedilol |
SMP00367 |
| Esmolol Pathway |
Esmolol |
SMP00301 |
| Labetalol Pathway |
Labetalol |
SMP00368 |
| Metoprolol Pathway |
Metoprolol |
SMP00302 |
| Nadolol Pathway |
Nadolol |
SMP00303 |
| Nebivolol Pathway |
Nebivolol |
SMP00366 |
| Oxprenolol Pathway |
Oxprenolol |
SMP00304 |
| Penbutolol Pathway |
Penbutolol |
SMP00305 |
| Pindolol Pathway |
Pindolol |
SMP00306 |
| Propranolol Pathway |
Propranolol |
SMP00307 |
| Bisphosphonates | ||
| Alendronate pathway |
Alendronate |
SMP00095 |
| Ibandronate Pathway |
Ibandronate |
SMP00079 |
| Pamidronate Pathway |
Pamidronate |
SMP00117 |
| Risedronate Pathway |
Risedronate |
SMP00112 |
| Zoledronate Pathway |
Zoledronate |
SMP00107 |
| Calcium Channel Blockers | ||
| Amlodipine Pathway |
Amlodipine |
SMP00376 |
| Diltiazem Pathway |
Diltiazem |
SMP00359 |
| Felodipine Pathway |
Felodipine |
SMP00377 |
| Isradipine Pathway |
Isradipine |
SMP00378 |
| Nifedipine Pathway |
Nifedipine |
SMP00379 |
| Nimodipine Pathway |
Nimodipine |
SMP00380 |
| Nisoldipine Pathway |
Nisoldipine |
SMP00381 |
| Nitrendipine Pathway |
Nitrendipine |
SMP00382 |
| Verapamil Pathway |
Verapamil |
SMP00375 |
| Direct Thrombin Inhibitors | ||
| Argatroban Pathway |
Argatroban |
SMP00276 |
| Bivalirudin Pathway |
Bivalirudin |
SMP00277 |
| Lepirudin Pathway |
Lepirudin |
SMP00278 |
| Ximelagatran Pathway |
Ximelagatran |
SMP00279 |
| Fibrinolytic Agents | ||
| Alteplase Pathway |
Alteplase |
SMP00280 |
| Anistreplase Pathway |
Anistreplase |
SMP00281 |
| Reteplase Pathway |
Reteplase |
SMP00285 |
| Streptokinase Pathway |
Streptokinase |
SMP00282 |
| Tenecteplase Pathway |
Tenecteplase |
SMP00283 |
| Urokinase Pathway |
Urokinase |
SMP00284 |
| Glucocorticoids | ||
| Prednisolone Pathway |
Prednisolone |
SMP00441 |
| Prednisone Pathway |
Prednisolone Prednisone |
SMP00440 |
| H2-receptor Antagonists | ||
| Cimetidine Pathway |
Cimetidine |
SMP00232 |
| Famotidine Pathway |
Famotidine |
SMP00231 |
| Nizatidine Pathway |
Nizatidine |
SMP00233 |
| Ranitidine Pathway |
Ranitidine |
SMP00230 |
| Heparins | ||
| Ardeparin Pathway |
Ardeparin |
SMP00275 |
| Enoxaparin Pathway |
Enoxaparin |
SMP00272 |
| Fondaparinux Pathway |
Fondaparinux sodium |
SMP00273 |
| Heparin Pathway |
Heparin |
SMP00274 |
| Immunosuppressants | ||
| Methotrexate Pathway |
Methotrexate |
SMP00432 |
| Insulin Secretagogues | ||
| Nateglinide Pathway |
Nateglinide |
SMP00453 |
| Repaglinide Pathway |
Repaglinide |
SMP00454 |
| K+-sparing diuretics | ||
| Amiloride Pathway |
Amiloride |
SMP00133 |
| Eplerenone Pathway |
Eplerenone |
SMP00135 |
| Spironolactone Pathway |
Spironolactone |
SMP00134 |
| Triamterene Pathway |
Triamterene |
SMP00132 |
| Local Anaesthetics | ||
| Benzocaine Pathway |
Benzocaine |
SMP00392 |
| Bupivacaine Pathway |
Bupivacaine |
SMP00393 |
| Chloroprocaine Pathway |
Chloroprocaine |
SMP00394 |
| Cocaine Pathway |
Cocaine |
SMP00395 |
| Dibucaine Pathway |
Dibucaine |
SMP00396 |
| Levobupivacaine Pathway |
Levobupivacaine |
SMP00397 |
| Lidocaine (Local Anaesthetic) Pathway |
Lidocaine |
SMP00398 |
| Mepivacaine Pathway |
Mepivacaine |
SMP00399 |
| Oxybuprocaine Pathway |
Oxybuprocaine |
SMP00400 |
| Prilocaine Pathway |
Prilocaine |
SMP00401 |
| Procaine Pathway |
Procaine |
SMP00402 |
| Proparacaine Pathway |
Proparacaine |
SMP00403 |
| Ropivacaine Pathway |
Ropivacaine |
SMP00404 |
| Loop Diuretics | ||
| Bumetanide Pathway |
Bumetanide |
SMP00088 |
| Ethacrynic Acid pathway |
Ethacrynic acid |
SMP00097 |
| Furosemide Pathway |
Furosemide |
SMP00115 |
| Torsemide Pathway |
Torasemide |
SMP00118 |
| Miscellaneous | ||
| Disulfiram Pathway |
Cocaine Disulfiram |
SMP00429 |
| Nicotine Pathway |
Nicotine |
SMP00431 |
| NSAIDs | ||
| Acetylsalicylic Acid Pathway |
Acetylsalicylic acid |
SMP00083 |
| Bromfenac Pathway |
Bromfenac |
SMP00102 |
| Celecoxib Pathway |
Celecoxib |
SMP00096 |
| Diclofenac Pathway |
Diclofenac |
SMP00093 |
| Diflunisal Pathway |
Diflunisal |
SMP00289 |
| Etodolac Pathway |
Etodolac |
SMP00084 |
| Ibuprofen Pathway |
Ibuprofen |
SMP00086 |
| Indomethacin Pathway |
Indomethacin |
SMP00104 |
| Ketoprofen Pathway |
Ketoprofen |
SMP00085 |
| Ketorolac Pathway |
Ketorolac |
SMP00098 |
| Mefanamic Acid Pathway |
Mefenamic acid |
SMP00109 |
| Meloxicam Pathway |
Meloxicam |
SMP00106 |
| Nabumetone Pathway |
Nabumetone |
SMP00114 |
| Naproxen Pathway |
Naproxen |
SMP00120 |
| Oxaprozin Pathway |
Oxaprozin |
SMP00113 |
| Piroxicam Pathway |
Piroxicam |
SMP00077 |
| Rofecoxib Pathway |
Rofecoxib |
SMP00087 |
| Sulindac Pathway |
Sulindac |
SMP00094 |
| Suprofen Pathway |
Suprofen |
SMP00101 |
| Valdecoxib Pathway |
Valdecoxib |
SMP00116 |
| Nucleotide Reverse Transcriptase Inhibitors (ntRTIs) | ||
| Adefovir Dipivoxil Pathway |
Adefovir Dipivoxil |
SMP00418 |
| Tenofovir Pathway |
Tenofovir |
SMP00419 |
| Opioids | ||
| Alfentanil Pathway |
Alfentanil |
SMP00413 |
| Carfentanil Pathway |
Carfentanil |
SMP00414 |
| Codeine Pathway |
Codeine Morphine |
SMP00405 |
| Fentanyl Pathway |
Fentanyl |
SMP00415 |
| Heroin Pathway |
Morphine Heroin |
SMP00407 |
| Hydrocodone Pathway |
Hydrocodone |
SMP00411 |
| Hydromorphone Pathway |
Hydromorphone |
SMP00410 |
| Methadone Pathway |
Methadone |
SMP00408 |
| Morphine Pathway |
Morphine |
SMP00406 |
| Oxycodone Pathway |
Oxycodone |
SMP00409 |
| Oxymorphone Pathway |
Oxymorphone |
SMP00412 |
| Remifentanil Pathway |
Remifentanil |
SMP00416 |
| Sufentanil Pathway |
Sufentanil |
SMP00417 |
| Platelet-aggregation Inhibitors | ||
| Abciximab Pathway |
Abciximab |
SMP00265 |
| Cilostazol Pathway |
Cilostazol |
SMP00263 |
| Clopidogrel Pathway |
Clopidogrel |
SMP00260 |
| Dipyridamole (Antiplatelet) Pathway |
Dipyridamole |
SMP00264 |
| Eptifibatide Pathway |
Eptifibatide |
SMP00266 |
| Ticlopidine Pathway |
Ticlopidine |
SMP00261 |
| Tirofiban Pathway |
Tirofiban |
SMP00267 |
| Podophyllotoxins | ||
| Etoposide Pathway |
Etoposide |
SMP00442 |
| Teniposide Pathway |
Teniposide |
SMP00443 |
| Proton Pump Inhibitors | ||
| Esomeprazole Pathway |
Esomeprazole |
SMP00225 |
| Lansoprazole Pathway |
Lansoprazole |
SMP00227 |
| Omeprazole Pathway |
Omeprazole |
SMP00226 |
| Pantoprazole Pathway |
Pantoprazole |
SMP00228 |
| Rabeprazole Pathway |
Rabeprazole |
SMP00229 |
| Purine Antimetabolites | ||
| Azathioprine Pathway |
Mercaptopurine Azathioprine |
SMP00427 |
| Mercaptopurine Pathway |
Mercaptopurine |
SMP00428 |
| Thioguanine Pathway |
Mercaptopurine Thioguanine |
SMP00430 |
| Selective Estrogen Receptor Modifiers | ||
| Tamoxifen Pathway |
Tamoxifen |
SMP00471 |
| Selective Serotonin Reuptake Inhibitors (SSRIs) | ||
| Citalopram Pathway |
Citalopram |
SMP00424 |
| Escitalopram Pathway |
Escitalopram |
SMP00425 |
| Fluoxetine Pathway |
Fluoxetine |
SMP00426 |
| Statins | ||
| Atorvastatin Pathway |
Atorvastatin |
SMP00131 |
| Cerivastatin Pathway |
Cerivastatin |
SMP00111 |
| Fluvastatin Pathway |
Fluvastatin |
SMP00119 |
| Lovastatin Pathway |
Lovastatin |
SMP00099 |
| Pravastatin Pathway |
Pravastatin |
SMP00089 |
| Rosuvastatin Pathway |
Rosuvastatin |
SMP00092 |
| Sulfonylureas | ||
| Glibenclamide Pathway |
Glyburide |
SMP00460 |
| Gliclazide Pathway |
Gliclazide |
SMP00461 |
| Taxanes | ||
| Docetaxel Pathway |
Docetaxel |
SMP00435 |
| Paclitaxel Pathway |
Paclitaxel |
SMP00434 |
| Thiazide Diuretics | ||
| Bendroflumethiazide Pathway |
Bendroflumethiazide |
SMP00090 |
| Chlorothiazide Pathway |
Chlorothiazide |
SMP00078 |
| Cyclothiazide Pathway |
Cyclothiazide |
SMP00103 |
| Hydrochlorothiazide Pathway |
Hydrochlorothiazide |
SMP00100 |
| Hydroflumethiazide Pathway |
Hydroflumethiazide |
SMP00108 |
| Methyclothiazide Pathway |
Methyclothiazide |
SMP00081 |
| Polythiazide Pathway |
Polythiazide |
SMP00080 |
| Quinethazone Pathway |
Quinethazone |
SMP00091 |
| Trichlormethiazide Pathway |
Trichlormethiazide |
SMP00121 |
| Thiazide-like Diuretics | ||
| Chlorthalidone Pathway |
Chlorthalidone |
SMP00122 |
| Indapamide Pathway |
Indapamide |
SMP00110 |
| Metolazone Pathway |
Metolazone |
SMP00105 |
| Tricyclic Antidepressants (TCAs) | ||
| Desipramine Pathway |
Desipramine |
SMP00423 |
| Imipramine Pathway |
Imipramine Desipramine |
SMP00422 |
| VEGF inhibitors | ||
| Bevacizumab Pathway |
Bevacizumab |
SMP00420 |
| Vitamin K Reductase Inhibitors | ||
| Acenocoumarol Pathway |
Acenocoumarol |
SMP00269 |
| Dicumarol Pathway |
Dicumarol |
SMP00270 |
| Phenprocoumon Pathway |
Phenprocoumon |
SMP00271 |
| Warfarin Pathway |
Warfarin |
SMP00268 |