Statistics

Drug Statistics

Description	Count
Total Number of Small Molecule Drugs	6580
Total Number of Biotech Drugs	131
Total Number of Approved Drugs	1578
Total Number of Approved Small Molecule Drugs	1447
Total Number of Nutraceutical Drugs	85
Total Number of Experimental Drugs	5080
Total Number of Illicit Drugs	188
Total Number of Withdrawn Drugs	70
Total Number of Drugs	6711

Target Statistics

Drug Group	Drug Type	Number of drug-target associations	Number of unique targets
Approved	Biotech	511	208
Approved	Small Molecule	5148	1429
Nutraceutical	Small Molecule	873	691
Experimental	Small Molecule	8478	2917
Illicit	Small Molecule	567	77
Withdrawn	Biotech	5	5
Withdrawn	Small Molecule	179	111
All Drugs		14276	4081

Chart?chd=t:29,16,21,33,59,61,112,202,340,539,62&chxl=1:%7c%23%20of%20drugs%7c3:%7c%23%20of%20targets%7c&chco=4d89f9&chxp=1,50%7c3,50&chds=0,539&chs=750x275&chtt=number%20of%20targets%20per%20drug%7c(up%20to%2010)&chbh=12,5,5&cht=bhg&chxr=0,0,539&chxt=x,x,y,y

Transporter Statistics

Drug Group	Drug Type	Number of drug-transporter associations	Number of unique transporters
Approved	Biotech	14	12
Approved	Small Molecule	1263	85
Nutraceutical	Small Molecule	84	41
Experimental	Small Molecule	149	38
Illicit	Small Molecule	20	9
Withdrawn	Small Molecule	31	18
All Drugs		1440	88

Chart?chd=t:6,2,5,7,18,27,24,63,88,206,1118&chxl=1:%7c%23%20of%20drugs%7c3:%7c%23%20of%20transporters%7c&chco=4d89f9&chxp=1,50%7c3,50&chds=0,1118&chs=750x275&chtt=number%20of%20transporters%20per%20drug%7c(up%20to%2010)&chbh=12,5,5&cht=bhg&chxr=0,0,1118&chxt=x,x,y,y

Enzyme Statistics

Drug Group	Drug Type	Number of drug-enzyme associations	Number of unique enzymes
Approved	Biotech	20	13
Approved	Small Molecule	2717	180
Nutraceutical	Small Molecule	142	101
Experimental	Small Molecule	92	32
Illicit	Small Molecule	153	25
Withdrawn	Small Molecule	143	35
All Drugs		2893	184

Chart?chd=t:23,18,34,36,35,52,71,83,140,261,804&chxl=1:%7c%23%20of%20drugs%7c3:%7c%23%20of%20enzymes%7c&chco=4d89f9&chxp=1,50%7c3,50&chds=0,804&chs=750x275&chtt=number%20of%20enzymes%20per%20drug%7c(up%20to%2010)&chbh=12,5,5&cht=bhg&chxr=0,0,804&chxt=x,x,y,y

Carrier Statistics

Drug Group	Drug Type	Number of drug-carrier associations	Number of unique carriers
Approved	Biotech	2	1
Approved	Small Molecule	172	19
Nutraceutical	Small Molecule	12	8
Experimental	Small Molecule	92	16
Illicit	Small Molecule	7	3
Withdrawn	Small Molecule	3	3
All Drugs		269	24

Chart?chd=t:1,4,18,122,1433&chxl=1:%7c%23%20of%20drugs%7c3:%7c%23%20of%20carriers%7c&chco=4d89f9&chxp=1,50%7c3,50&chds=0,1433&chs=750x275&chtt=number%20of%20carriers%20per%20drug%7c(up%20to%2010)&chbh=12,5,5&cht=bhg&chxr=0,0,1433&chxt=x,x,y,y

Link-out Statistics

Resource	Approved Drugs with Links	Approved Coverage
ChemSpider (small molecule only)	1192	82.38%
PubChem Compound (small molecule only)	1203	83.14%
KEGG Compound	857	54.31%
KEGG Drug	954	60.46%
ChEBI (small molecule only)	940	59.57%
Wikipedia	1419	89.92%
Binding DB	417	26.43%
ChEMBL (small molecule only)	940	59.57%
Stitch	1203	76.24%
Therapeutic Targets Database (TTD)	1336	84.66%
PharmGKB	1135	71.93%
Drug Product Database	950	60.2%
RxList	996	63.12%
Drugs.com	1084	68.69%

Other Statistics

Description	Count
Number of PDB Accessions	3154
Total Number of Sequences	8771