Structure of the cytochrome b6f complex of oxygenic photosynthesis: tuning the cavity.

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Kurisu G, Zhang H, Smith JL, Cramer WA

Structure of the cytochrome b6f complex of oxygenic photosynthesis: tuning the cavity.

Science. 2003 Nov 7;302(5647):1009-14. Epub 2003 Oct 2.

PubMed ID
14526088 [ View in PubMed
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Abstract

The cytochrome b6f complex provides the electronic connection between the photosystem I and photosystem II reaction centers of oxygenic photosynthesis and generates a transmembrane electrochemical proton gradient for adenosine triphosphate synthesis. A 3.0 angstrom crystal structure of the dimeric b6f complex from the thermophilic cyanobacterium Mastigocladus laminosus reveals a large quinone exchange cavity, stabilized by lipid, in which plastoquinone, a quinone-analog inhibitor, and a novel heme are bound. The core of the b6f complex is similar to the analogous respiratory cytochrome bc1 complex, but the domain arrangement outside the core and the complement of prosthetic groups are strikingly different. The motion of the Rieske iron-sulfur protein extrinsic domain, essential for electron transfer, must also be different in the b6f complex.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Cytochrome b6P83791Details
Cytochrome b6-f complex subunit 4P83792Details
Cytochrome b6-f complex iron-sulfur subunitP83794Details
Cytochrome fP83793Details
Cytochrome b6-f complex subunit 5P83797Details
Cytochrome b6-f complex subunit 6P83795Details
Cytochrome b6-f complex subunit 7P83796Details
Cytochrome b6-f complex subunit 8P83798Details