The homology of complement factor C8 gamma chain and alpha-1-microglobulin.
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Hunt LT, Elzanowski A, Barker WC
The homology of complement factor C8 gamma chain and alpha-1-microglobulin.
Biochem Biophys Res Commun. 1987 Nov 30;149(1):282-8.
- PubMed ID
- 2446620 [ View in PubMed]
- Abstract
The sequence of the complement factor C8 gamma chain shares a remarkable degree of similarity with that of alpha-1-microglobulin, a member of the alpha-2u-globulin superfamily. This superfamily comprises a diverse group of distantly related animal proteins possessing characteristic structural features and similar functions. Comparison of the C8 gamma chain with these proteins supports its homology to them and suggests a possible functional role.