A protein required for secretion of cholera toxin through the outer membrane of Vibrio cholerae.
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Sandkvist M, Morales V, Bagdasarian M
A protein required for secretion of cholera toxin through the outer membrane of Vibrio cholerae.
Gene. 1993 Jan 15;123(1):81-6.
- PubMed ID
- 8423007 [ View in PubMed]
- Abstract
A gene essential for the secretion of cholera toxin from the periplasm of Vibrio cholerae into the extracellular medium has been isolated and its nucleotide sequence determined. It encodes a cytoplasmic protein of 56 kDa that exhibits a high degree of similarity to gene products required for extracellular protein secretion in several other Gram- organisms. Sequence similarities in its potential ATP-binding site suggest that the protein may act as an energy provider or signal transducer in the process of extracellular secretion.