Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation.
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Crump MP, Rajarathnam K, Kim KS, Clark-Lewis I, Sykes BD
Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation.
J Biol Chem. 1998 Aug 28;273(35):22471-9.
- PubMed ID
- 9712872 [ View in PubMed]
- Abstract
The solution structure of the CCR3-specific chemokine, eotaxin, has been determined by NMR spectroscopy. The quaternary structure of eotaxin was investigated by ultracentrifugation and NMR, and it was found to be in equilibrium between monomer and dimer under a wide range of conditions. At pH