Human platelet-derived growth factor (PDGF): amino-terminal amino acid sequence.
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Antoniades HN, Hunkapiller MW
Human platelet-derived growth factor (PDGF): amino-terminal amino acid sequence.
Science. 1983 May 27;220(4600):963-5.
- PubMed ID
- 6844921 [ View in PubMed]
- Abstract
Human platelet-derived growth factor (PDGF) obtained from outdated human platelets was subjected to amino-terminal amino acid sequence analysis by automated Edman degradation. Despite the apparent presence of limited proteolytic degradation of the protein derived from this method, the sequence analysis reveals two primary peptide sequences and suggests that active PDGF is composed of two, possibly homologous, peptides linked by a disulfide bond or bonds.