The electronic and serotonin receptor binding affinity properties of N,N-dimethyltryptamine analogs.
Article Details
- CitationCopy to clipboard
Glennon RA, Gessner PK
The electronic and serotonin receptor binding affinity properties of N,N-dimethyltryptamine analogs.
Res Commun Chem Pathol Pharmacol. 1977 Nov;18(3):453-65.
- PubMed ID
- 270770 [ View in PubMed]
- Abstract
The electronic properties of a series of N,N-dimethyltryptamines and related analogs, for which binding affinity data are available, were examined using both a pi-electron and an all-valence electron method. The results suggest that affinity is related to the ability of these compounds to donate electrons in a localized charge transfer manner from the 4-position of the indole nucleus.
DrugBank Data that Cites this Article
- Drug Targets
Drug Target Kind Organism Pharmacological Action Actions Dimethyltryptamine 5-hydroxytryptamine receptor 6 Protein Humans YesNot Available Details