A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells.
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Muller MM, Ruppert S, Schaffner W, Matthias P
A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells.
Nature. 1988 Dec 8;336(6199):544-51.
- PubMed ID
- 2904653 [ View in PubMed]
- Abstract
The complementary DNA coding for a lymphocyte-specific transcription factor binding to the DNA 'octamer' sequence TNATTTGCAT has been cloned. The nucleotide sequence shows homology to the homoeobox domain. Expression of this cDNA in HeLa cells is sufficient for a strong transcriptional activation of B-cell-specific promoters.