Cloning and expression of human adenylyl cyclase type VI in normal thyroid tissues.
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Wicker R, Catalan AG, Cailleux A, Starenki D, Stengel D, Sarasin A, Suarez HG
Cloning and expression of human adenylyl cyclase type VI in normal thyroid tissues.
Biochim Biophys Acta. 2000 Sep 7;1493(1-2):279-83.
- PubMed ID
- 10978539 [ View in PubMed]
- Abstract
The adenylyl cyclase type VI gene expressed in human normal thyroid tissue was cloned and sequenced. The cDNA sequence (6463 nt) is susceptible to code for a 1168 aa protein. Northern blots using specific probes showed that the expression of adenylyl cyclase type VI gene was significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue, in one follicular cold adenoma or in one papillary carcinoma.