Sertraline-associated hair loss.

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Ghanizadeh A

Sertraline-associated hair loss.

J Drugs Dermatol. 2008 Jul;7(7):693-4.

PubMed ID

18664165 [ View in PubMed

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Abstract

INTRODUCTION: Many commonly prescribed prescription drugs such as dopaminergic therapies can cause temporary hair loss. Sertraline is a selective serotonin reuptake inhibitor. Its relative potency for dopamine reuptake inhibition is one of its differentiations with other selective serotonin reuptake inhibitors such as fluoxetine. CASE REPORT: This is a report of a woman with a major depressive disorder who complained of diffuse scalp hair loss during treatment with sertraline. This case is unique because before taking sertraline and after the discontinuation of sertraline, the patient had taken fluoxetine. There was no report of hair loss during the fluoxetine therapy. DISCUSSION: The different impacts of sertraline and fluoxetine on dopamine reuptake inhibition were identified as a possible reason for this side effect. Therefore, this rare side effect of sertraline should be noted and further studies may show that switching from one selective serotonin reuptake inhibitor to another may prevent hair loss.

DrugBank Data that Cites this Article

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Sertraline	Sodium-dependent dopamine transporter	Protein	Humans	Unknown	Inhibitor Binder	Details