Human metabotropic glutamate receptor type 7: molecular cloning and mRNA distribution in the CNS.
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Makoff A, Pilling C, Harrington K, Emson P
Human metabotropic glutamate receptor type 7: molecular cloning and mRNA distribution in the CNS.
Brain Res Mol Brain Res. 1996 Aug;40(1):165-70.
- PubMed ID
- 8840028 [ View in PubMed]
- Abstract
Human metabotropic glutamate receptor type 7 (mGluR7) cDNA clones were isolated from a medulla cDNA library. The sequence, which includes a polymorphism, has 92% DNA sequence identity with rat mGluR7 and the predicted protein sequence has 99% identity. In-situ hybridization studies on human brain sections showed that mGluR7 mRNA has a widespread distribution with highest levels in the hippocampal formation, cerebral cortex and cerebellum.