Use of Favipiravir to Treat Lassa Virus Infection in Macaques.
Article Details
- CitationCopy to clipboard
Rosenke K, Feldmann H, Westover JB, Hanley PW, Martellaro C, Feldmann F, Saturday G, Lovaglio J, Scott DP, Furuta Y, Komeno T, Gowen BB, Safronetz D
Use of Favipiravir to Treat Lassa Virus Infection in Macaques.
Emerg Infect Dis. 2018 Sep;24(9):1696-1699. doi: 10.3201/eid2409.180233. Epub 2018 Sep 17.
- PubMed ID
- 29882740 [ View in PubMed]
- Abstract
Lassa virus, the cause of Lassa fever in humans, is endemic to West Africa. Treatment of Lassa fever is primarily supportive, although ribavirin has shown limited efficacy if administered early during infection. We tested favipiravir in Lassa virus-viremic macaques and found that 300 mg/kg daily for 2 weeks successfully treated infection.
DrugBank Data that Cites this Article
- Drugs