Reversal of mydriasis by dapiprazole.
Article Details
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Allinson RW, Gerber DS, Bieber S, Hodes BL
Reversal of mydriasis by dapiprazole.
Ann Ophthalmol. 1990 Apr;22(4):131-3, 138.
- PubMed ID
- 1972008 [ View in PubMed]
- Abstract
The effect of topical dapiprazole, an alpha-adrenergic receptor blocker, in reversing mydriasis was studied in 50 subjects who received tropicamide 1% and phenylephrine 2.5%. There was a significant difference in the decrease in pupil size between the eye that received dapiprazole and the control eye. This study suggests that dapiprazole 0.5% eye drops are effective and safe in reversing mydriasis after instillation of tropicamide 1% and phenylephrine 2.5%.
DrugBank Data that Cites this Article
- Drug Targets
Drug Target Kind Organism Pharmacological Action Actions Dapiprazole Alpha-1B adrenergic receptor Protein Humans YesAntagonistDetails Dapiprazole Alpha-1D adrenergic receptor Protein Humans YesAntagonistDetails