The dinB operon and spontaneous mutation in Escherichia coli.
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McKenzie GJ, Magner DB, Lee PL, Rosenberg SM
The dinB operon and spontaneous mutation in Escherichia coli.
J Bacteriol. 2003 Jul;185(13):3972-7. doi: 10.1128/JB.185.13.3972-3977.2003.
- PubMed ID
- 12813093 [ View in PubMed]
- Abstract
Apparently conflicting data regarding the role of SOS-inducible, error-prone DNA polymerase IV (DinB) in spontaneous mutation are resolved by the finding that mutation is reduced by a polar allele with which dinB and neighboring yafN are deleted but not by two nonpolar dinB alleles. We demonstrate the existence of a dinB operon that contains four genes, dinB-yafN-yafO-yafP. The results imply a role for yafN, yafO, and/or yafP in spontaneous mutation.