Error-prone DNA polymerases: novel structures and the benefits of infidelity.
Article Details
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Friedberg EC, Fischhaber PL, Kisker C
Error-prone DNA polymerases: novel structures and the benefits of infidelity.
Cell. 2001 Oct 5;107(1):9-12. doi: 10.1016/s0092-8674(01)00509-8.
- PubMed ID
- 11595180 [ View in PubMed]
- Abstract
Studies on several recently discovered error-prone DNA polymerases reveal novel structures that may explain the low fidelity of this general class of enzymes, a number of which are involved in the replicative bypass (translesion synthesis) of base damage in DNA.