Synthesis of the bicyclic core of tagetitoxin.
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Plet JR, Porter MJ
Synthesis of the bicyclic core of tagetitoxin.
Chem Commun (Camb). 2006 Mar 21;(11):1197-9. Epub 2006 Feb 14.
- PubMed ID
- 16518489 [ View in PubMed]
- Abstract
A synthesis of the 9-oxa-3-thiabicyclo[3.3.1]nonane ring system, which constitutes the core of the RNA polymerase inhibitor tagetitoxin, has been achieved through cyclisation of a thiol onto an electrophilic ketone.
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