Kinase domain mutations in cancer: implications for small molecule drug design strategies.

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Bikker JA, Brooijmans N, Wissner A, Mansour TS

Kinase domain mutations in cancer: implications for small molecule drug design strategies.

J Med Chem. 2009 Mar 26;52(6):1493-509. doi: 10.1021/jm8010542.

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19239229 [ View in PubMed

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Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
Gefitinib	Epidermal growth factor receptor	Kd (nM)	35.3	N/A	N/A	Details