Synthesis and pharmacological studies of N-[4-[2-hydroxy-3-[[2-[4-(1H-imidazol-1- yl)phenoxy]ethyl]amino]propoxy]phenyl]methanesulfonamide, a novel antiarrhythmic agent with class II and class III activities.

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Morgan TK Jr, Lis R, Lumma WC Jr, Wohl RA, Nickisch K, Phillips GB, Lind JM, Lampe JW, Di Meo SV, Reiser HJ, et al.

Synthesis and pharmacological studies of N-[4-[2-hydroxy-3-[[2-[4-(1H-imidazol-1- yl)phenoxy]ethyl]amino]propoxy]phenyl]methanesulfonamide, a novel antiarrhythmic agent with class II and class III activities.

J Med Chem. 1990 Apr;33(4):1087-90.

PubMed ID

2319556 [ View in PubMed

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Abstract

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DrugBank Data that Cites this Article

Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
Sotalol	Beta-1 adrenergic receptor	IC 50 (nM)	9000	N/A	N/A	Details