Inhibitors of serine proteases as potential therapeutic agents: the road from thrombin to tryptase to cathepsin G.

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Maryanoff BE

Inhibitors of serine proteases as potential therapeutic agents: the road from thrombin to tryptase to cathepsin G.

J Med Chem. 2004 Feb 12;47(4):769-87.

PubMed ID

14761180 [ View in PubMed

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Abstract

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DrugBank Data that Cites this Article

Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
Bis-Napthyl Beta-Ketophosphonic Acid	Cathepsin G	IC 50 (nM)	4100	N/A	N/A	Details
RWJ-51084	Trypsin-1	Ki (nM)	30	N/A	N/A	Details
RWJ-56423	Trypsin-1	Ki (nM)	8.1	N/A	N/A	Details