9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl) derivatives of adenine and 3-deazaadenine: potent inhibitors of bovine liver S-adenosylhomocysteine hydrolase.

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Narayanan SR, Keller BT, Borcherding DR, Scholtz SA, Borchardt RT

9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl) derivatives of adenine and 3-deazaadenine: potent inhibitors of bovine liver S-adenosylhomocysteine hydrolase.

J Med Chem. 1988 Mar;31(3):500-3.

PubMed ID

3346868 [ View in PubMed

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Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
(1'R,2'S)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-yl)Adenine	Adenosylhomocysteinase	Ki (nM)	41	N/A	N/A	Details