Pharmacokinetic studies of the fragrance compound 1,8-cineol in humans during inhalation.
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Jager W, Nasel B, Nasel C, Binder R, Stimpfl T, Vycudilik W, Buchbauer G
Pharmacokinetic studies of the fragrance compound 1,8-cineol in humans during inhalation.
Chem Senses. 1996 Aug;21(4):477-80.
- PubMed ID
- 8866111 [ View in PubMed]
- Abstract
The present study was undertaken to investigate the pharmacokinetics of 1,8-cineol in human subjects during prolonged inhalation. The results showed that 1,8-cineol is well absorbed from breathing air, with a peak plasma concentration after approximately 18 min. The elimination of this fragrance compound from the blood is biphasic, with a mean distribution half-life of 6.7 min and an elimination half-life of 104.6 min.
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