Mitochondrial genome variation and evolutionary history of Australian and New Guinean aborigines.

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Ingman M, Gyllensten U

Mitochondrial genome variation and evolutionary history of Australian and New Guinean aborigines.

Genome Res. 2003 Jul;13(7):1600-6.

PubMed ID
12840039 [ View in PubMed
]
Abstract

To study the evolutionary history of the Australian and New Guinean indigenous peoples, we analyzed 101 complete mitochondrial genomes including populations from Australia and New Guinea as well as from Africa, India, Europe, Asia, Melanesia, and Polynesia. The genetic diversity of the Australian mitochondrial sequences is remarkably high and is similar to that found across Asia. This is in contrast to the pattern seen in previously described Y-chromosome data where an Australia-specific haplotype was found at high frequency. The mitochondrial genome data indicate that Australia was colonized between 40 and 70 thousand years ago, either by a single migration from a heterogeneous source population or by multiple movements of smaller groups occurring over a period of time. Some Australian and New Guinea sequences form clades, suggesting the possibility of a joint colonization and/or admixture between the two regions.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
NADH-ubiquinone oxidoreductase chain 3P03897Details
NADH-ubiquinone oxidoreductase chain 4LP03901Details
Cytochrome c oxidase subunit 1P00395Details
NADH-ubiquinone oxidoreductase chain 6P03923Details
NADH-ubiquinone oxidoreductase chain 1P03886Details
NADH-ubiquinone oxidoreductase chain 4P03905Details
NADH-ubiquinone oxidoreductase chain 5P03915Details
NADH-ubiquinone oxidoreductase chain 2P03891Details
Cytochrome c oxidase subunit 2P00403Details
ATP synthase subunit aP00846Details